Published in Eur J Immunol on February 01, 2005
Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover. J Exp Med (2007) 5.58
Differential natural killer cell-mediated inhibition of HIV-1 replication based on distinct KIR/HLA subtypes. J Exp Med (2007) 4.14
HIV-1 adaptation to NK-cell-mediated immune pressure. Nature (2011) 2.59
TCR clonotypes modulate the protective effect of HLA class I molecules in HIV-1 infection. Nat Immunol (2012) 2.04
A viral CTL escape mutation leading to immunoglobulin-like transcript 4-mediated functional inhibition of myelomonocytic cells. J Exp Med (2007) 1.88
NK cells in HIV-1 infection: evidence for their role in the control of HIV-1 infection. J Intern Med (2009) 1.50
Loss of viral fitness and cross-recognition by CD8+ T cells limit HCV escape from a protective HLA-B27-restricted human immune response. J Clin Invest (2009) 1.46
Correlates of protective cellular immunity revealed by analysis of population-level immune escape pathways in HIV-1. J Virol (2012) 1.29
Polymorphic sites away from the Bw4 epitope that affect interaction of Bw4+ HLA-B with KIR3DL1. J Immunol (2008) 1.19
An early HIV mutation within an HLA-B*57-restricted T cell epitope abrogates binding to the killer inhibitory receptor 3DL1. J Virol (2011) 1.13
Protective effect of human leukocyte antigen B27 in hepatitis C virus infection requires the presence of a genotype-specific immunodominant CD8+ T-cell epitope. Hepatology (2010) 1.11
KIR3DL2 binds to HLA-B27 dimers and free H chains more strongly than other HLA class I and promotes the expansion of T cells in ankylosing spondylitis. J Immunol (2013) 0.97
Contribution of KIR3DL1/3DS1 to ankylosing spondylitis in human leukocyte antigen-B27 Caucasian populations. Arthritis Res Ther (2006) 0.95
Mutational and structural analysis of KIR3DL1 reveals a lineage-defining allotypic dimorphism that impacts both HLA and peptide sensitivity. J Immunol (2014) 0.94
Genetic diversity of the KIR/HLA system and outcome of patients with metastatic colorectal cancer treated with chemotherapy. PLoS One (2014) 0.92
Peptide-Dependent Recognition of HLA-B*57:01 by KIR3DS1. J Virol (2015) 0.92
Selection of an HLA-C*03:04-Restricted HIV-1 p24 Gag Sequence Variant Is Associated with Viral Escape from KIR2DL3+ Natural Killer Cells: Data from an Observational Cohort in South Africa. PLoS Med (2015) 0.90
Sequence variations in HIV-1 p24 Gag-derived epitopes can alter binding of KIR2DL2 to HLA-C*03:04 and modulate primary natural killer cell function. AIDS (2014) 0.89
Conformation of peptides bound to the transporter associated with antigen processing (TAP). Proc Natl Acad Sci U S A (2011) 0.88
Predicting important residues and interaction pathways in proteins using Gaussian Network Model: binding and stability of HLA proteins. PLoS Comput Biol (2010) 0.86
Triple bypass: complicated paths to HIV escape. J Exp Med (2007) 0.84
The interaction of KIR3DL1*001 with HLA class I molecules is dependent upon molecular microarchitecture within the Bw4 epitope. J Immunol (2014) 0.83
Degenerate recognition of MHC class I molecules with Bw4 and Bw6 motifs by a killer cell Ig-like receptor 3DL expressed by macaque NK cells. J Immunol (2012) 0.82
Structure of HLA-A*1101 in complex with a hepatitis B peptide homologue. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.81
The structure and stability of the monomorphic HLA-G are influenced by the nature of the bound peptide. J Mol Biol (2010) 0.81
The yin-yang of KIR3DL1/S1: molecular mechanisms and cellular function. Crit Rev Immunol (2013) 0.81
The complex and specific pMHC interactions with diverse HIV-1 TCR clonotypes reveal a structural basis for alterations in CTL function. Sci Rep (2014) 0.80
MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape. Nat Struct Mol Biol (2017) 0.79
Killer cell immunoglobulin-like receptors in HLA-B27-associated acute anterior uveitis, with and without axial spondyloarthropathy. Invest Ophthalmol Vis Sci (2009) 0.79
Characterization of a proteasome and TAP-independent presentation of intracellular epitopes by HLA-B27 molecules. J Biol Chem (2012) 0.78
HLA-B27: portraying immunodominant viral epitopes. Eur J Immunol (2005) 0.78
Immunoinformatic docking approach for the analysis of KIR3DL1/HLA-B interaction. Biomed Res Int (2013) 0.77
Interaction pattern of Arg 62 in the A-pocket of differentially disease-associated HLA-B27 subtypes suggests distinct TCR binding modes. PLoS One (2012) 0.76
Key role of human leukocyte antigen in modulating human immunodeficiency virus progression: An overview of the possible applications. World J Virol (2015) 0.76
The domain landscape of virus-host interactomes. Biomed Res Int (2014) 0.76
Loss of recognition by cross-reactive T cells and its relation to a C-terminus-induced conformational reorientation of an HLA-B*2705-bound peptide. Protein Sci (2010) 0.75
Human Leukocyte Antigen (HLA) and Immune Regulation: How Do Classical and Non-Classical HLA Alleles Modulate Immune Response to Human Immunodeficiency Virus and Hepatitis C Virus Infections? Front Immunol (2017) 0.75
Prediction of peptide binding to a major histocompatibility complex class I molecule based on docking simulation. J Comput Aided Mol Des (2016) 0.75
A whole-genome association study of major determinants for host control of HIV-1. Science (2007) 15.19
Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections. Nat Med (2002) 10.03
The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection. J Exp Med (2009) 6.22
Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility. Nat Genet (2011) 5.56
A time- and cost-efficient system for high-level protein production in mammalian cells. Acta Crystallogr D Biol Crystallogr (2006) 5.17
Acute HIV-1 Infection. N Engl J Med (2011) 4.84
Preexisting influenza-specific CD4+ T cells correlate with disease protection against influenza challenge in humans. Nat Med (2012) 4.74
Medicine. The need for a global HIV vaccine enterprise. Science (2003) 4.70
Escape from the dominant HLA-B27-restricted cytotoxic T-lymphocyte response in Gag is associated with a dramatic reduction in human immunodeficiency virus type 1 replication. J Virol (2007) 4.64
Memory T cells established by seasonal human influenza A infection cross-react with avian influenza A (H5N1) in healthy individuals. J Clin Invest (2008) 4.30
Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL. Nature (2002) 3.78
A procedure for setting up high-throughput nanolitre crystallization experiments. Crystallization workflow for initial screening, automated storage, imaging and optimization. Acta Crystallogr D Biol Crystallogr (2005) 3.75
Common genetic variation and the control of HIV-1 in humans. PLoS Genet (2009) 3.68
The crystal structure of human CD1d with and without alpha-galactosylceramide. Nat Immunol (2005) 3.53
Immune activation and CD8+ T-cell differentiation towards senescence in HIV-1 infection. PLoS Biol (2004) 3.20
A structural basis for immunodominant human T cell receptor recognition. Nat Immunol (2003) 3.15
Characterization of CD4(+) CTLs ex vivo. J Immunol (2002) 3.10
Transmission of single HIV-1 genomes and dynamics of early immune escape revealed by ultra-deep sequencing. PLoS One (2010) 3.02
Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci. Nat Genet (2013) 2.87
Structure of human CD1b with bound ligands at 2.3 A, a maze for alkyl chains. Nat Immunol (2002) 2.70
Design and pre-clinical evaluation of a universal HIV-1 vaccine. PLoS One (2007) 2.61
Polyfunctional T cell responses are a hallmark of HIV-2 infection. Eur J Immunol (2008) 2.59
Structural basis of Nipah and Hendra virus attachment to their cell-surface receptor ephrin-B2. Nat Struct Mol Biol (2008) 2.58
Glycoprotein structural genomics: solving the glycosylation problem. Structure (2007) 2.40
The length of lipids bound to human CD1d molecules modulates the affinity of NKT cell TCR and the threshold of NKT cell activation. J Exp Med (2007) 2.37
Human inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind preferentially to HLA-G. Proc Natl Acad Sci U S A (2003) 2.33
A functional and structural basis for TCR cross-reactivity in multiple sclerosis. Nat Immunol (2002) 2.31
The structural dynamics and energetics of an immunodominant T cell receptor are programmed by its Vbeta domain. Immunity (2008) 2.31
Structural and kinetic basis for heightened immunogenicity of T cell vaccines. J Exp Med (2005) 2.22
Analysis of CD161 expression on human CD8+ T cells defines a distinct functional subset with tissue-homing properties. Proc Natl Acad Sci U S A (2010) 2.19
Opposing effects of HLA class I molecules in tuning autoreactive CD8+ T cells in multiple sclerosis. Nat Med (2008) 2.19
Annulling a dangerous liaison: vaccination strategies against AIDS and tuberculosis. Nat Med (2005) 2.18
Positional cloning of a novel gene influencing asthma from chromosome 2q14. Nat Genet (2003) 2.16
The arthritis-associated HLA-B*27:05 allele forms more cell surface B27 dimer and free heavy chain ligands for KIR3DL2 than HLA-B*27:09. Rheumatology (Oxford) (2013) 2.14
Molecular signatures distinguish human central memory from effector memory CD8 T cell subsets. J Immunol (2005) 2.12
Conflicting selective forces affect T cell receptor contacts in an immunodominant human immunodeficiency virus epitope. Nat Immunol (2006) 2.11
Characterization of the CD4+ T cell response to Epstein-Barr virus during primary and persistent infection. J Exp Med (2003) 2.01
T cell cross-reactivity and conformational changes during TCR engagement. J Exp Med (2004) 1.99
CD56bright human NK cells differentiate into CD56dim cells: role of contact with peripheral fibroblasts. J Immunol (2007) 1.99
Cross-reactive cytotoxic T lymphocytes against a HIV-1 p24 epitope in slow progressors with B*57. AIDS (2002) 1.92
Distinct binding modes of two epitopes in Gab2 that interact with the SH3C domain of Grb2. Structure (2009) 1.89
Mature CD8(+) T lymphocyte response to viral infection during fetal life. J Clin Invest (2003) 1.85
Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance. Nat Immunol (2009) 1.83
Th17 cells expressing KIR3DL2+ and responsive to HLA-B27 homodimers are increased in ankylosing spondylitis. J Immunol (2011) 1.81
A human immunodeficiency virus 1 (HIV-1) clade A vaccine in clinical trials: stimulation of HIV-specific T-cell responses by DNA and recombinant modified vaccinia virus Ankara (MVA) vaccines in humans. J Gen Virol (2004) 1.80
An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly. Nat Struct Mol Biol (2010) 1.80
CD56bright NK cells are enriched at inflammatory sites and can engage with monocytes in a reciprocal program of activation. J Immunol (2004) 1.78
CCL3L1 and HIV/AIDS susceptibility. Nat Med (2009) 1.73
The ligand-binding face of the semaphorins revealed by the high-resolution crystal structure of SEMA4D. Nat Struct Biol (2003) 1.68
Pivotal Advance: Invariant NKT cells reduce accumulation of inflammatory monocytes in the lungs and decrease immune-pathology during severe influenza A virus infection. J Leukoc Biol (2011) 1.66
Optimal vaccination strategies for 2009 pandemic H1N1 and seasonal influenza vaccines in humans. Vaccine (2010) 1.65
Crystal structures of the endoplasmic reticulum aminopeptidase-1 (ERAP1) reveal the molecular basis for N-terminal peptide trimming. Proc Natl Acad Sci U S A (2011) 1.64
The crystal structure of human CD1b with a bound bacterial glycolipid. J Immunol (2004) 1.64
Aromatic residues at the edge of the antibody combining site facilitate viral glycoprotein recognition through membrane interactions. Proc Natl Acad Sci U S A (2010) 1.64
Structure of a tyrosine phosphatase adhesive interaction reveals a spacer-clamp mechanism. Science (2007) 1.64
A dual binding mode for RhoGTPases in plexin signalling. PLoS Biol (2011) 1.63
HIV-specific cytotoxic T cells from long-term survivors select a unique T cell receptor. J Exp Med (2004) 1.60
Structures of an MHC class I molecule from B21 chickens illustrate promiscuous peptide binding. Immunity (2007) 1.60
Structures of three HIV-1 HLA-B*5703-peptide complexes and identification of related HLAs potentially associated with long-term nonprogression. J Immunol (2005) 1.60
Proteoglycan-specific molecular switch for RPTPσ clustering and neuronal extension. Science (2011) 1.59
Clinical experience with plasmid DNA- and modified vaccinia virus Ankara-vectored human immunodeficiency virus type 1 clade A vaccine focusing on T-cell induction. J Gen Virol (2007) 1.59
Structural basis of semaphorin-plexin signalling. Nature (2010) 1.58
Fitness costs and diversity of the cytotoxic T lymphocyte (CTL) response determine the rate of CTL escape during acute and chronic phases of HIV infection. J Virol (2011) 1.57
Cell-surface expression and immune receptor recognition of HLA-B27 homodimers. Arthritis Rheum (2002) 1.56
Vaccine route, dose and type of delivery vector determine patterns of primary CD8+ T cell responses. Eur J Immunol (2005) 1.55
Prolonged activation of virus-specific CD8+T cells after acute B19 infection. PLoS Med (2005) 1.53
Crystal structure of the GluR2 amino-terminal domain provides insights into the architecture and assembly of ionotropic glutamate receptors. J Mol Biol (2009) 1.53
Lymphoblastoid cells express HLA-B27 homodimers both intracellularly and at the cell surface following endosomal recycling. Eur J Immunol (2003) 1.53
Structural and functional studies of LRP6 ectodomain reveal a platform for Wnt signaling. Dev Cell (2011) 1.50
T cell-mediated autoimmune disease due to low-affinity crossreactivity to common microbial peptides. Immunity (2009) 1.50
Ex vivo phenotype and frequency of influenza virus-specific CD4 memory T cells. J Virol (2004) 1.48
The transmembrane semaphorin Sema4D/CD100, an inhibitor of axonal growth, is expressed on oligodendrocytes and upregulated after CNS lesion. J Neurosci (2003) 1.46
Loss of viral fitness and cross-recognition by CD8+ T cells limit HCV escape from a protective HLA-B27-restricted human immune response. J Clin Invest (2009) 1.46
HLA-B27 heavy chain homodimers are expressed in HLA-B27 transgenic rodent models of spondyloarthritis and are ligands for paired Ig-like receptors. J Immunol (2004) 1.45
Dual interaction of JAM-C with JAM-B and alpha(M)beta2 integrin: function in junctional complexes and leukocyte adhesion. Mol Biol Cell (2005) 1.45
Copy number variation of KIR genes influences HIV-1 control. PLoS Biol (2011) 1.44
Effects of cytotoxic T lymphocytes (CTL) directed against a single simian immunodeficiency virus (SIV) Gag CTL epitope on the course of SIVmac239 infection. J Virol (2002) 1.44
Dynamics of T cell responses in HIV infection. J Immunol (2002) 1.44
Biology of CD1- and MR1-restricted T cells. Annu Rev Immunol (2014) 1.44
Phenotypic analysis of antigen-specific T lymphocytes. Science. 1996. 274: 94-96. J Immunol (2011) 1.42
Relationship between functional profile of HIV-1 specific CD8 T cells and epitope variability with the selection of escape mutants in acute HIV-1 infection. PLoS Pathog (2011) 1.42
Immunoglobulin superfamily cell adhesion molecules: zippers and signals. Curr Opin Cell Biol (2007) 1.41
Eukaryotic expression: developments for structural proteomics. Acta Crystallogr D Biol Crystallogr (2006) 1.41
Structural and functional properties of the human notch-1 ligand binding region. Structure (2004) 1.40