Published in Br J Cancer on February 14, 2005
Where is VEGF in the body? A meta-analysis of VEGF distribution in cancer. Br J Cancer (2007) 1.61
A systems biology perspective on sVEGFR1: its biological function, pathogenic role and therapeutic use. J Cell Mol Med (2009) 1.59
Granulocyte macrophage colony-stimulating factor inhibits breast cancer growth and metastasis by invoking an anti-angiogenic program in tumor-educated macrophages. Cancer Res (2009) 1.57
High levels of vascular endothelial growth factor and its receptors (VEGFR-1, VEGFR-2, neuropilin-1) are associated with worse outcome in breast cancer. Hum Pathol (2008) 1.26
Overexpression of RRM2 decreases thrombspondin-1 and increases VEGF production in human cancer cells in vitro and in vivo: implication of RRM2 in angiogenesis. Mol Cancer (2009) 1.14
A single-nucleotide polymorphism in a half-binding site creates p53 and estrogen receptor control of vascular endothelial growth factor receptor 1. Mol Cell Biol (2007) 1.13
A compartment model of VEGF distribution in humans in the presence of soluble VEGF receptor-1 acting as a ligand trap. PLoS One (2009) 1.09
The association between vascular endothelial growth factor expression in invasive breast cancer and survival varies with intrinsic subtypes and use of adjuvant systemic therapy: results from the Nurses' Health Study. Breast Cancer Res Treat (2011) 1.06
Opposing roles for HIF-1α and HIF-2α in the regulation of angiogenesis by mononuclear phagocytes. Blood (2010) 1.02
Effects of oestradiol and tamoxifen on VEGF, soluble VEGFR-1, and VEGFR-2 in breast cancer and endothelial cells. Br J Cancer (2005) 1.00
Effects of diabetes on myocardial capillary density and serum angiogenesis biomarkers in male rats. Clinics (Sao Paulo) (2011) 0.93
Disrupted balance of angiogenic and antiangiogenic signalings in preeclampsia. J Pregnancy (2011) 0.91
Computational kinetic model of VEGF trapping by soluble VEGF receptor-1: effects of transendothelial and lymphatic macromolecular transport. Physiol Genomics (2009) 0.90
The prognostic and predictive value of mRNA expression of vascular endothelial growth factor family members in breast cancer: a study in primary tumors of high-risk early breast cancer patients participating in a randomized Hellenic Cooperative Oncology Group trial. Breast Cancer Res (2012) 0.89
The role of vascular endothelial growth factor a polymorphisms in breast cancer. Int J Mol Sci (2012) 0.87
Vascular endothelial growth factor receptor-1 expression in breast cancer and its correlation to vascular endothelial growth factor a. Int J Breast Cancer (2013) 0.84
Increased plasma levels of soluble vascular endothelial growth factor receptor 1 (sFlt-1) in women by moderate exercise and increased plasma levels of vascular endothelial growth factor in overweight/obese women. Eur J Cancer Prev (2013) 0.84
Mesenchymal Stem Cells Induce Directional Migration of Invasive Breast Cancer Cells through TGF-β. Sci Rep (2015) 0.82
Diabetic retinopathy and vascular endothelial growth factor. J Res Med Sci (2013) 0.77
Splice Variants of the RTK Family: Their Role in Tumour Progression and Response to Targeted Therapy. Int J Mol Sci (2017) 0.75
Expression and clinical significance of vascular endothelial growth factor and fms-related tyrosine kinase 1 in colorectal cancer. Oncol Lett (2015) 0.75
Prognostic evaluation of VEGFA genotypes and haplotypes in a cohort of Brazilian women with non metastatic breast cancer. Cancer Biol Ther (2016) 0.75
Loss of membranous VEGFR1 expression is associated with an adverse phenotype and shortened survival in breast cancer. Mol Med Rep (2016) 0.75
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med (2004) 49.02
The biology of VEGF and its receptors. Nat Med (2003) 32.13
Circulating angiogenic factors and the risk of preeclampsia. N Engl J Med (2004) 14.00
Estrogen receptor status in breast cancer is associated with remarkably distinct gene expression patterns. Cancer Res (2001) 8.34
Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor. Proc Natl Acad Sci U S A (1993) 5.02
Clinical applications of angiogenic growth factors and their inhibitors. Nat Med (1999) 4.26
Identification of a natural soluble form of the vascular endothelial growth factor receptor, FLT-1, and its heterodimerization with KDR. Biochem Biophys Res Commun (1996) 3.33
Structure and function of VEGF/VEGF-receptor system involved in angiogenesis. Cell Struct Funct (2001) 2.48
Paracrine expression of a native soluble vascular endothelial growth factor receptor inhibits tumor growth, metastasis, and mortality rate. Proc Natl Acad Sci U S A (1998) 2.11
Levels of soluble vascular endothelial growth factor (VEGF) receptor 1 in astrocytic tumors and its relation to malignancy, vascularity, and VEGF-A. Clin Cancer Res (2003) 1.82
Vascular endothelial growth factor is associated with the efficacy of endocrine therapy in patients with advanced breast carcinoma. Cancer (2003) 1.74
High tumor levels of vascular endothelial growth factor predict poor response to systemic therapy in advanced breast cancer. Cancer Res (2001) 1.70
Correlation of vascular endothelial growth factor content with recurrences, survival, and first relapse site in primary node-positive breast carcinoma after adjuvant treatment. J Clin Oncol (2000) 1.68
Prognostic value of vascular endothelial growth factor in breast cancer. Oncologist (2000) 1.61
Vascular endothelial growth factor: its prognostic, predictive, and therapeutic implications. Lancet Oncol (2001) 1.54
Heregulin selectively upregulates vascular endothelial growth factor secretion in cancer cells and stimulates angiogenesis. Oncogene (2000) 1.50
Significance of vascular endothelial growth factor (VEGF)/soluble VEGF receptor-1 relationship in breast cancer. Int J Cancer (2002) 1.34
Transcriptional regulation of vascular endothelial growth factor by estradiol and tamoxifen in breast cancer cells: a complex interplay between estrogen receptors alpha and beta. Cancer Res (2002) 1.34
The influence of oxygen tension and pH on the expression of platelet-derived endothelial cell growth factor/thymidine phosphorylase in human breast tumor cells grown in vitro and in vivo. Cancer Res (1997) 1.31
Tamoxifen inhibits secretion of vascular endothelial growth factor in breast cancer in vivo. Cancer Res (2003) 1.25
An angiogenic switch in breast cancer involves estrogen and soluble vascular endothelial growth factor receptor 1. J Natl Cancer Inst (2004) 1.24
Suppression of tumor angiogenesis and growth by gene transfer of a soluble form of vascular endothelial growth factor receptor into a remote organ. Cancer Res (2000) 1.17
Vascular endothelial growth factor up-regulates its receptor fms-like tyrosine kinase 1 (FLT-1) and a soluble variant of FLT-1 in human vascular endothelial cells. Cancer Res (1997) 1.10
Genes commonly upregulated by hypoxia in human breast cancer cells MCF-7 and MDA-MB-231. Biomed Pharmacother (2003) 0.99
Adenovirus-mediated soluble FLT-1 gene therapy for ovarian carcinoma. Clin Cancer Res (2001) 0.98
Soluble vascular endothelial growth factor receptor 1, and not receptor 2, is an independent prognostic factor in acute myeloid leukemia and myelodysplastic syndromes. Cancer (2004) 0.97
Gene therapy for pancreatic cancer using an adenovirus vector encoding soluble flt-1 vascular endothelial growth factor receptor. Pancreas (2002) 0.96
Transduction of soluble Flt-1 gene to peritoneal mesothelial cells can effectively suppress peritoneal metastasis of gastric cancer. Cancer Res (2004) 0.92
Detection and quantification of complexed and free soluble human vascular endothelial growth factor receptor-1 (sVEGFR-1) by ELISA. J Immunol Methods (1999) 0.85
Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components. Immunity (1999) 17.40
Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product. J Immunol (1999) 16.86
Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity (1999) 11.64
Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein. Cell (1992) 10.78
Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo. Nature (1992) 10.10
Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1. Blood (1996) 5.31
Cloning of human, mouse and fission yeast recombination genes homologous to RAD51 and recA. Nat Genet (1993) 4.96
Organization of the recA gene of Escherichia coli. Proc Natl Acad Sci U S A (1980) 4.90
Stimulation by Rad52 of yeast Rad51-mediated recombination. Nature (1998) 4.31
Significance of macrophage chemoattractant protein-1 in macrophage recruitment, angiogenesis, and survival in human breast cancer. Clin Cancer Res (2000) 3.86
Complex formation and functional versatility of Mre11 of budding yeast in recombination. Cell (1998) 3.80
Nucleotide sequence of the lexA gene of E. coli. Cell (1981) 3.61
Biosynthesis of a 42-kD Polypeptide in the Cytoplasmic Membrane of the Cyanobacterium Anacystis nidulans Strain R2 during Adaptation to Low CO(2) Concentration. Plant Physiol (1986) 3.18
Homologous recombination and the roles of double-strand breaks. Trends Biochem Sci (1995) 3.10
Kinetic properties of the blue-light response of stomata. Proc Natl Acad Sci U S A (1985) 3.09
Quantification of angiogenesis in solid human tumours: an international consensus on the methodology and criteria of evaluation. Eur J Cancer (1996) 3.07
Characteristics of purified recA protein and the regulation of its synthesis in vivo. Cold Spring Harb Symp Quant Biol (1979) 2.93
Type II collagen-induced murine arthritis. I. Induction and perpetuation of arthritis require synergy between humoral and cell-mediated immunity. J Immunol (1988) 2.80
Close relationship between autoimmune pancreatitis and multifocal fibrosclerosis. Gut (2003) 2.71
Rad52 forms ring structures and co-operates with RPA in single-strand DNA annealing. Genes Cells (1998) 2.66
Primary intracranial germ cell tumors: a clinical analysis of 153 histologically verified cases. J Neurosurg (1997) 2.60
Primary structure of the RAD52 gene in Saccharomyces cerevisiae. Mol Cell Biol (1984) 2.56
Significant correlation of monocyte chemoattractant protein-1 expression with neovascularization and progression of breast carcinoma. Cancer (2001) 2.51
Replication of bacteriophage DNA. I. Replication of DNA of lambda phage defective in early functions. J Mol Biol (1968) 2.46
VEGF and VEGF-C: specific induction of angiogenesis and lymphangiogenesis in the differentiated avian chorioallantoic membrane. Dev Biol (1997) 2.43
T cell activation-associated hepatic injury: mediation by tumor necrosis factors and protection by interleukin 6. J Exp Med (1994) 2.31
Replication of bacteriophage DNA, II. Structure of replicating DNA of phage lambda. Proc Natl Acad Sci U S A (1968) 2.29
Two pigment proteins in spinach chloroplasts. Biochim Biophys Acta (1966) 2.27
RNase H confers specificity in the dnaA-dependent initiation of replication at the unique origin of the Escherichia coli chromosome in vivo and in vitro. Proc Natl Acad Sci U S A (1984) 2.26
Vascular endothelial growth factor and glioma angiogenesis: coordinate induction of VEGF receptors, distribution of VEGF protein and possible in vivo regulatory mechanisms. Int J Cancer (1994) 2.24
Regulation of SOS functions: purification of E. coli LexA protein and determination of its specific site cleaved by the RecA protein. Cell (1981) 2.20
A cytotoxic ribonuclease which specifically cleaves four isoaccepting arginine tRNAs at their anticodon loops. Proc Natl Acad Sci U S A (2000) 2.19
Saccharomyces cerevisiae recA homologues RAD51 and DMC1 have both distinct and overlapping roles in meiotic recombination. Genes Cells (1997) 2.18
Discontinuous DNA replication. Annu Rev Biochem (1980) 2.14
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942. Proc Natl Acad Sci U S A (1999) 2.14
Novel mechanism for endothelial dysfunction: dysregulation of dimethylarginine dimethylaminohydrolase. Circulation (1999) 2.14
Initiation of enzymatic replication at the origin of the Escherichia coli chromosome: primase as the sole priming enzyme. Proc Natl Acad Sci U S A (1985) 2.08
Enhancement of tumor growth and vascular density by transfection of vascular endothelial cell growth factor into MCF-7 human breast carcinoma cells. J Natl Cancer Inst (1995) 2.07
IgG4-related sclerosing disease incorporating sclerosing pancreatitis, cholangitis, sialadenitis and retroperitoneal fibrosis with lymphadenopathy. Pancreatology (2005) 2.06
Effects of gender, age, and fitness level on response of VO2max to training in 60-71 yr olds. J Appl Physiol (1985) (1991) 2.05
Cellular responses to bacterial cell wall components are mediated through MyD88-dependent signaling cascades. Int Immunol (2000) 2.05
Localization of RecA-like recombination proteins on chromosomes of the lily at various meiotic stages. Genes Dev (1995) 2.04
Synthetic lipid A with endotoxic and related biological activities comparable to those of a natural lipid A from an Escherichia coli re-mutant. Infect Immun (1985) 2.04
Domain structure and dynamics in the helical filaments formed by RecA and Rad51 on DNA. Proc Natl Acad Sci U S A (2001) 2.03
Mutant p53 potentiates protein kinase C induction of vascular endothelial growth factor expression. Oncogene (1994) 2.01
Augmentation of transvascular transport of macromolecules and nanoparticles in tumors using vascular endothelial growth factor. Cancer Res (1999) 2.00
Ingested arsenic and internal cancer: a historical cohort study followed for 33 years. Am J Epidemiol (1995) 1.99
Replication of phage lambda DNA. Cold Spring Harb Symp Quant Biol (1968) 1.95
Genetically engineered mutant of the cyanobacterium Synechococcus PCC 7942 defective in nitrate transport. Proc Natl Acad Sci U S A (1989) 1.88
Two types of functionally distinct NAD(P)H dehydrogenases in Synechocystis sp. strain PCC6803. J Biol Chem (2000) 1.87
Prognostic significance of vascular endothelial growth factor protein in node-negative breast carcinoma. J Natl Cancer Inst (1997) 1.87
Gene expressions of Toll-like receptor 2, but not Toll-like receptor 4, is induced by LPS and inflammatory cytokines in mouse macrophages. J Immunol (2000) 1.86
Negative control of replication initiation by a novel chromosomal locus exhibiting exceptional affinity for Escherichia coli DnaA protein. Genes Dev (1998) 1.85
Induction of vascular endothelial growth factor by tumor necrosis factor alpha in human glioma cells. Possible roles of SP-1. J Biol Chem (1996) 1.81
Kynurenic acid concentrations are reduced in Huntington's disease cerebral cortex. J Neurol Sci (1992) 1.79
Effect of ultraviolet irradiation on bacteriophage lambda immunity. J Mol Biol (1967) 1.77
A simple assessment of dyspnoea as a prognostic indicator in idiopathic pulmonary fibrosis. Eur Respir J (2010) 1.72
Functional domains of Escherichia coli recA protein deduced from the mutational sites in the gene. Mol Gen Genet (1984) 1.71
An immunohistochemical study of developing glomeruli in human fetal kidneys. Kidney Int (2000) 1.69
Structure-activity relationships of oligo-beta-glucoside elicitors of phytoalexin accumulation in soybean. Plant Cell (1991) 1.68
The role of an alternative sigma factor in motility and pilus formation in the cyanobacterium Synechocystis sp. strain PCC6803. Proc Natl Acad Sci U S A (1999) 1.68
Regulation of nitric oxide synthesis by dimethylarginine dimethylaminohydrolase. Br J Pharmacol (1996) 1.68
Isolation of a recombinant influenza virus (Hsw 1 N2) from swine in Japan. Arch Virol (1980) 1.66
Release and complex formation of soluble VEGFR-1 from endothelial cells and biological fluids. Lab Invest (2000) 1.66
Adaptation to Low CO(2) Level in a Mutant of Anacystis nidulans R(2) which Requires High CO(2) for Growth. Plant Physiol (1987) 1.65
Construction and characterization of the deletion mutant of hupA and hupB genes in Escherichia coli. J Mol Biol (1988) 1.64
miR-489 is a tumour-suppressive miRNA target PTPN11 in hypopharyngeal squamous cell carcinoma (HSCC). Br J Cancer (2010) 1.61
Structure and expression of human thrombomodulin, a thrombin receptor on endothelium acting as a cofactor for protein C activation. EMBO J (1987) 1.60
AIDS-associated Kaposi's sarcoma cells in culture express vascular endothelial growth factor. Biochem Biophys Res Commun (1992) 1.60
Initiation of enzymatic replication at the origin of the Escherichia coli chromosome: contributions of RNA polymerase and primase. Proc Natl Acad Sci U S A (1985) 1.59
Expression of toll-like receptor 2 on gamma delta T cells bearing invariant V gamma 6/V delta 1 induced by Escherichia coli infection in mice. J Immunol (2000) 1.59
A novel DnaA protein-binding site at 94.7 min on the Escherichia coli chromosome. Mol Microbiol (1996) 1.58
Immunobiologically active lipid A analogs synthesized according to a revised structural model of natural lipid A. Infect Immun (1984) 1.57
Molecular epidemiology and phylogenetic analysis of Sapporo-like viruses. Arch Virol (2002) 1.57
Distinct constitutive and low-CO2-induced CO2 uptake systems in cyanobacteria: genes involved and their phylogenetic relationship with homologous genes in other organisms. Proc Natl Acad Sci U S A (2001) 1.57
Mutation of ndh genes leads to inhibition of CO(2) uptake rather than HCO(3)(-) uptake in Synechocystis sp. strain PCC 6803. J Bacteriol (2000) 1.56
Assay of RNA-linked nascent DNA pieces with polynucleotide kinase. Biochem Biophys Res Commun (1975) 1.55
Preparation and characterization of monoclonal antibodies directed to the tumor-associated O-linked sialosyl-2----6 alpha-N-acetylgalactosaminyl (sialosyl-Tn) epitope. Cancer Res (1988) 1.54
Computer assisted image analysis to assess colonization of recipient seminiferous tubules by spermatogonial stem cells from transgenic donor mice. Mol Reprod Dev (1999) 1.53
Cerebral infarction within six hours of onset: prediction of completed infarction with technetium-99m-HMPAO SPECT. J Nucl Med (1994) 1.51
Health-related quality of life in patients with idiopathic pulmonary fibrosis. What is the main contributing factor? Respir Med (2005) 1.51
Absortive lysogenization of bacteriophage lambda b2 and residual immunity of non-lysogenic segregants. J Mol Biol (1967) 1.51
Primary gastric T-cell lymphoma with and without human T-lymphotropic virus type 1. Cancer (1997) 1.49
Cooperative effect of TNFalpha, bFGF, and VEGF on the formation of tubular structures of human microvascular endothelial cells in a fibrin matrix. Role of urokinase activity. J Cell Biol (1996) 1.49
Concomitant major hepatectomy and inferior vena cava reconstruction. J Am Coll Surg (1999) 1.48
Pacing failure due to markedly increased stimulation threshold 2 years after implantation: successful management with oral prednisolone: a case report. Pacing Clin Electrophysiol (1989) 1.48
Tumor-induced immune dysfunction. Cancer Immunol Immunother (1999) 1.47
Effect of FK506 eye drops on late and delayed-type responses in ocular allergy models. Clin Exp Allergy (2003) 1.47
Morquio disease: isolation, characterization and expression of full-length cDNA for human N-acetylgalactosamine-6-sulfate sulfatase. Biochem Biophys Res Commun (1991) 1.46
Energization and activation of inorganic carbon uptake by light in cyanobacteria. Plant Physiol (1987) 1.46
Duocarmycin SA, a new antitumor antibiotic from Streptomyces sp. J Antibiot (Tokyo) (1990) 1.45
Purification and characterization of thin pili of IncI1 plasmids ColIb-P9 and R64: formation of PilV-specific cell aggregates by type IV pili. J Bacteriol (1998) 1.43
Germ cell genotype controls cell cycle during spermatogenesis in the rat. Biol Reprod (1998) 1.41
Comparison of treatments for hepatolithiasis: hepatic resection versus cholangioscopic lithotomy. J Am Coll Surg (1999) 1.40
Observation of B(0)(s)-->Psi(2S)Phi and measurement of the ratio of branching fractions Beta(B(0)(s)-->Psi(2S)Phi)/Beta(B(0)(s)-->J/PsiPhi). Phys Rev Lett (2006) 1.40
Cortical and subcortical vestibular response to caloric stimulation detected by functional magnetic resonance imaging. Brain Res Cogn Brain Res (2001) 1.40
Concentrations of vascular endothelial growth factor in the sera of normal controls and cancer patients. Clin Cancer Res (1996) 1.39
A case of Hashimoto's thyroiditis with antibodies to thyroid hormone analogues. Clin Chim Acta (1992) 1.39
Function of RNase H in DNA replication revealed by RNase H defective mutants of Escherichia coli. Mol Gen Genet (1984) 1.39
Renal refractoriness to phosphaturic action of parathyroid hormone in a patient with hypomagnesemia. Intern Med (1995) 1.39