Functional interaction between APOE4 and LDL receptor isoforms in Alzheimer's disease.

PubWeight™: 0.88‹?›

🔗 View Article (PMC 1735987)

Published in J Med Genet on February 01, 2005

Authors

D Cheng1, R Huang, I S Lanham, H M Cathcart, M Howard, E H Corder, S E Poduslo

Author Affiliations

1: Institute of Molecular Medicine and Genetics, Medical College of Georgia, Augusta, GA 30912, USA.

Articles cited by this

Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology (1984) 119.59

Inference of population structure using multilocus genotype data: linked loci and correlated allele frequencies. Genetics (2003) 53.11

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science (1993) 33.32

Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium. JAMA (1997) 17.88

Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. Science (1988) 13.54

Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease. Nat Genet (1994) 7.07

Molecular genetics of the LDL receptor gene in familial hypercholesterolemia. Hum Mutat (1992) 4.48

Haplotypes and SNPs in 13 lipid-relevant genes explain most of the genetic variance in high-density lipoprotein and low-density lipoprotein cholesterol. Hum Mol Genet (2004) 2.45

Harmful effects of increased LDLR expression in mice with human APOE*4 but not APOE*3. Arterioscler Thromb Vasc Biol (2003) 2.00

Genetic association of the low-density lipoprotein receptor-related protein gene (LRP), an apolipoprotein E receptor, with late-onset Alzheimer's disease. Neurology (1997) 1.58

Interactions of apolipoprotein E genotype, total cholesterol level, age, and sex in prediction of Alzheimer's disease: a case-control study. Neurology (1995) 1.55

Power for genetic association studies with random allele frequencies and genotype distributions. Am J Hum Genet (2004) 1.52

Functions of lipoprotein receptors in neurons. J Lipid Res (2003) 1.11

Potential genetic markers of sporadic Alzheimer's dementia. Psychiatr Genet (2001) 0.99

The apolipoprotein CI A allele as a risk factor for Alzheimer's disease. Neurochem Res (1998) 0.95

From cholesterol transport to signal transduction: low density lipoprotein receptor, very low density lipoprotein receptor, and apolipoprotein E receptor-2. Biochim Biophys Acta (2000) 0.92

Association of 3'-UTR polymorphisms of the oxidised LDL receptor 1 (OLR1) gene with Alzheimer's disease. J Med Genet (2003) 0.89

Molecular characterisation of a low-frequency mutation in exon 8 of the human low-density lipoprotein receptor gene. S Afr Med J (1989) 0.84

Effect of the StuI polymorphism in the LDL receptor gene (Ala 370 to Thr) on lipid levels in healthy individuals. Clin Genet (1995) 0.83

Role of common genetic polymorphisms in the LDL receptor gene in affecting plasma cholesterol levels in the general population. Arterioscler Thromb (1994) 0.81

Articles by these authors

(truncated to the top 100)

IL-10 inhibits cytokine production by activated macrophages. J Immunol (1991) 13.13

IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells. J Immunol (1991) 11.04

Identification of a T cell-derived b cell growth factor distinct from interleukin 2. J Exp Med (1982) 9.49

Mutation of unique region of Bruton's tyrosine kinase in immunodeficient XID mice. Science (1993) 5.50

Regulation of B-cell growth and differentiation by soluble factors. Annu Rev Immunol (1983) 5.09

School-based programs to reduce sexual risk behaviors: a review of effectiveness. Public Health Rep (1994) 4.50

The biochemistry, biology, and role of interleukin 2 in the induction of cytotoxic T cell and antibody-forming B cell responses. Immunol Rev (1982) 4.43

Interleukin 10, a novel B cell stimulatory factor: unresponsiveness of X chromosome-linked immunodeficiency B cells. J Exp Med (1990) 4.30

Myelination in rat brain: method of myelin isolation. J Neurochem (1973) 4.01

Ly-1 B (B-1) cells are the main source of B cell-derived interleukin 10. Eur J Immunol (1992) 3.39

Association of protein kinase A and protein phosphatase 2B with a common anchoring protein. Science (1995) 3.34

Cyclic ADP-ribose production by CD38 regulates intracellular calcium release, extracellular calcium influx and chemotaxis in neutrophils and is required for bacterial clearance in vivo. Nat Med (2001) 3.33

Genetic recombination of bacterial plasmid DNA: effect of RecF pathway mutations on plasmid recombination in Escherichia coli. J Bacteriol (1985) 2.92

Continuous administration of anti-interleukin 10 antibodies delays onset of autoimmunity in NZB/W F1 mice. J Exp Med (1994) 2.71

Rapid, sensitive assay for staphylococcal enterotoxin and a comparison of serological methods. Appl Microbiol (1968) 2.58

Evidence for two distinct classes of murine B cell growth factors with activities in different functional assays. J Exp Med (1983) 2.56

Comparison of self-collected vaginal, vulvar and urine samples with physician-collected cervical samples for human papillomavirus testing to detect high-grade squamous intraepithelial lesions. CMAJ (2000) 2.36

The earliest T lineage-committed cells depend on IL-7 for Bcl-2 expression and normal cell cycle progression. Immunity (1997) 2.33

Immunoglobulin signal transduction guides the specificity of B cell-T cell interactions and is blocked in tolerant self-reactive B cells. J Exp Med (1994) 2.23

Continuous anti-interleukin 10 antibody administration depletes mice of Ly-1 B cells but not conventional B cells. J Exp Med (1992) 2.15

Expression of high affinity receptors for murine interleukin 4 (BSF-1) on hemopoietic and nonhemopoietic cells. J Immunol (1988) 1.94

Long-term culture of normal mouse B lymphocytes. Proc Natl Acad Sci U S A (1981) 1.94

Trauma outcome improves following the advanced trauma life support program in a developing country. J Trauma (1993) 1.91

Effect of preventive home visits by a nurse on the outcomes of frail elderly people in the community: a randomized controlled trial. CMAJ (2000) 1.86

Prevalence and risk factors for common vision problems in children: data from the ALSPAC study. Br J Ophthalmol (2008) 1.85

Hypothesis: microtubule instability and paired helical filament formation in the Alzheimer disease brain are related to apolipoprotein E genotype. Exp Neurol (1994) 1.84

Molecular biology of interleukin 4 and interleukin 5 genes and biology of their products that stimulate B cells, T cells and hemopoietic cells. Immunol Rev (1988) 1.84

Universal PCR amplification of mouse immunoglobulin gene variable regions: the design of degenerate primers and an assessment of the effect of DNA polymerase 3' to 5' exonuclease activity. J Immunol Methods (2000) 1.78

Biochemical and physicochemical characterization of mouse B cell growth factor: a lymphokine distinct from interleukin 2. J Immunol (1983) 1.73

Interleukin 2 induces antigen-reactive T cell lines to secrete BCGF-I. J Exp Med (1983) 1.71

Clinical application of apolipoprotein E genotyping to Alzheimer's disease. Lancet (1994) 1.71

Role of interleukin 1 in anti-immunoglobulin-induced B cell proliferation. J Exp Med (1983) 1.69

B cell growth and differentiation factors. Immunol Rev (1984) 1.61

Myelination in rat brain: changes in myelin composition during brain maturation. J Neurochem (1973) 1.59

Postpartum depression in women receiving public assistance: pilot study of an interpersonal-therapy-oriented group intervention. Am J Psychiatry (2001) 1.58

Identification of two glycoforms of the MUC5B mucin in human respiratory mucus. Evidence for a cysteine-rich sequence repeated within the molecule. J Biol Chem (1997) 1.52

Characterization of mucins from cultured normal human tracheobronchial epithelial cells. Am J Physiol Lung Cell Mol Physiol (2000) 1.52

There is a pathologic relationship between ApoE-epsilon 4 and Alzheimer's disease. Arch Neurol (1995) 1.51

Respiratory mucins: identification of core proteins and glycoforms. Biochem J (1996) 1.50

AKAP79 inhibits calcineurin through a site distinct from the immunophilin-binding region. J Biol Chem (1998) 1.49

Two-kidney, two clip renovascular hypertensive rats can be used as stroke-prone rats. Stroke (1998) 1.49

Bleeding vascular malformations of the intestine. Surgery (1978) 1.47

Soluble factors involved in B cell differentiation: identification of two distinct T cell-replacing factors (TRF). J Immunol (1983) 1.46

Physical association of starch biosynthetic enzymes with starch granules of maize endosperm. Granule-associated forms of starch synthase I and starch branching enzyme II. Plant Physiol (1996) 1.46

Comprehensive service programs for school-age pregnant girls. Children (1968) 1.44

Genome screen of late-onset Alzheimer's extended pedigrees identifies TRPC4AP by haplotype analysis. Am J Med Genet B Neuropsychiatr Genet (2009) 1.40

Inorganic polyphosphates in the acquisition of competence in Escherichia coli. J Biol Chem (1995) 1.39

Tooth surface recording. Br Dent J (2008) 1.38

Plasma concentrations of digoxin after oral administration in the fasting and postprandial ste. Br Med J (1971) 1.36

The Eczema Priority Setting Partnership: a collaboration between patients, carers, clinicians and researchers to identify and prioritize important research questions for the treatment of eczema. Br J Dermatol (2013) 1.34

Cyclin D2 is essential for BCR-mediated proliferation and CD5 B cell development. Int Immunol (2000) 1.33

Salivary mucin MG1 is comprised almost entirely of different glycosylated forms of the MUC5B gene product. Glycobiology (1999) 1.32

Prescription and nonprescription drug use among black and white community-residing elderly. Am J Public Health (1993) 1.30

Safe at home? Domestic violence and other homicides among women in New Mexico. Ann Emerg Med (1996) 1.28

Physical characterization of the MUC5AC mucin: a highly oligomeric glycoprotein whether isolated from cell culture or in vivo from respiratory mucous secretions. Biochem J (2000) 1.28

Simultaneous detection of multiple cytokines from conditioned media and patient's sera by an antibody-based protein array system. Anal Biochem (2001) 1.27

Human cell lines U-937, THP-1 and Mono Mac 6 represent relatively immature cells of the monocyte-macrophage cell lineage. Leukemia (1994) 1.25

Subacute sclerosing leukoencephalitis. II. Chemical studies including abnormal myelin and an abnormal ganglioside pattern. J Neuropathol Exp Neurol (1966) 1.24

Interleukin 4 is a growth factor for activated thymocytes: possible role in T-cell ontogeny. Proc Natl Acad Sci U S A (1987) 1.22

Poly-3-hydroxybutyrate/polyphosphate complexes form voltage-activated Ca2+ channels in the plasma membranes of Escherichia coli. Biophys J (1995) 1.21

The left atrial appendage: our most lethal human attachment! Surgical implications. Eur J Cardiothorac Surg (2000) 1.21

The development of the avian vertebral column. Anat Embryol (Berl) (2000) 1.19

Analysis of respiratory mucus glycoproteins in asthma: a detailed study from a patient who died in status asthmaticus. Am J Respir Cell Mol Biol (1995) 1.17

Factors predicting the cumulative outcome of IVF/ICSI treatment: a multivariable analysis of 2450 patients. Hum Reprod (2011) 1.17

Expression cloning of a cDNA encoding the murine interleukin 4 receptor based on ligand binding. Proc Natl Acad Sci U S A (1990) 1.17

Chlamydial cervicitis: testing the practice guidelines for presumptive diagnosis. CMAJ (1998) 1.17

Modified immunological status of anti-IL-10 treated mice. Cell Immunol (1993) 1.17

Assessment of the cervix after acetic acid wash: inter-rater agreement using photographs. Obstet Gynecol (2002) 1.16

Methods for separation and deglycosylation of mucin subunits. Anal Biochem (1995) 1.16

Physical characterization of a low-charge glycoform of the MUC5B mucin comprising the gel-phase of an asthmatic respiratory mucous plug. Biochem J (1999) 1.16

Design of a microfabricated magnetic cell separator. Electrophoresis (2001) 1.16

Myocardial and skeletal muscle concentrations of digoxin in patients on long-term therapy. Br Med J (1972) 1.14

Identification of two major populations of mucins in respiratory secretions. Am J Respir Crit Care Med (1994) 1.13

Is sitting-while-at-work associated with low back pain? A systematic, critical literature review. Scand J Public Health (2000) 1.13

Connexin 43 (cx43) enhances chemotherapy-induced apoptosis in human glioblastoma cells. Int J Cancer (2001) 1.12

Patient choice of treatment for postpartum depression: a pilot study. Arch Womens Ment Health (2006) 1.12

Neuronal soma and whole neuroglia of rat brain: a new isolation technique. Science (1970) 1.11

T-cell hybridoma secreting hemopoietic regulatory molecules: granulocyte-macrophage and eosinophil colony-stimulating factors. Cell (1979) 1.11

Administration of intracoronary bone marrow mononuclear cells on chronic myocardial infarction improves diastolic function. Heart (2008) 1.10

Fast-scanning high-flux microprobe for biological X-ray fluorescence microscopy and microXAS. J Synchrotron Radiat (2010) 1.10

Management of Acanthamoeba keratitis. A case report and review of the literature. Ophthalmology (1984) 1.09

Trauma mannequin assessment of management skills of surgical residents after advanced trauma life support training. J Surg Res (2000) 1.09

The work-related fatal injury study: numbers, rates and trends of work-related fatal injuries in New Zealand 1985-1994. N Z Med J (2001) 1.08

Activated B cells from patients with common variable immunodeficiency proliferate and synthesize immunoglobulin. J Clin Invest (1993) 1.07

T cell dependence and factor reconstitution of in vitro antibody responses to TNP-B. Abortus and TNP-Ficoll: restoration of depleted responses with chromatographed fractions of a T cell-derived factor. J Immunol (1983) 1.07

IL-10 production by CD5 B cells. Ann N Y Acad Sci (1992) 1.06

Rare occurrence of N-ras point mutations in Philadelphia chromosome positive chronic myeloid leukemia. Blood (1989) 1.06

Novel components and enzymatic activities of the human erythrocyte plasma membrane calcium pump. FEBS Lett (1997) 1.05

Phospholipase C-beta1 knockout mice exhibit endophenotypes modeling schizophrenia which are rescued by environmental enrichment and clozapine administration. Mol Psychiatry (2007) 1.05

The cardiac sodium channel mRNA is expressed in the developing and adult rat and human brain. Brain Res (2000) 1.05

Factors affecting performance on the American Board of Surgery in-training examination. Am J Surg (2001) 1.05

Multiple endocytic signals in the C-terminal tail of the cystic fibrosis transmembrane conductance regulator. Biochem J (2001) 1.04

Association of a monoamine oxidase B allele with Parkinson's disease. Ann Neurol (1993) 1.04

CD38 unresponsiveness of xid B cells implicates Bruton's tyrosine kinase (btk) as a regular of CD38 induced signal transduction. Int Immunol (1995) 1.04

Epithelial autonomy in the development of the inner ear of a bird embryo. Dev Biol (1990) 1.04

Vaginal self sampling versus physician cervical sampling for HPV among younger and older women. Sex Transm Infect (2006) 1.03

An IFN-gamma-dependent pathway plays a critical role in the pathogenesis of murine immunodeficiency syndrome induced by LP-BM5 murine leukemia virus. Int Immunol (1994) 1.03

Two malignant tumors in a polycystic kidney. J Urol (1969) 1.03

Genetic variants in brain-derived neurotrophic factor associated with Alzheimer's disease. J Med Genet (2007) 1.03

Identification of an essential region for growth signal transduction in the cytoplasmic domain of the human interleukin-4 receptor. J Biol Chem (1992) 1.03