Published in Proc Natl Acad Sci U S A on February 28, 2005
Niche regulation of corneal epithelial stem cells at the limbus. Cell Res (2007) 1.76
Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes Dev (2008) 1.41
Multipotent skin-derived precursors: adult neural crest-related precursors with therapeutic potential. Philos Trans R Soc Lond B Biol Sci (2008) 1.33
The canonical Wnt signaling antagonist DKK2 is an essential effector of PITX2 function during normal eye development. Dev Biol (2008) 1.31
Engineering stem cells into organs: topobiological transformations demonstrated by beak, feather, and other ectodermal organ morphogenesis. Curr Top Dev Biol (2006) 1.17
Down-regulation of Pax6 is associated with abnormal differentiation of corneal epithelial cells in severe ocular surface diseases. J Pathol (2008) 1.17
A new scenario for the evolutionary origin of hair, feather, and avian scales. J Anat (2009) 1.08
Defining hair follicles in the age of stem cell bioengineering. J Invest Dermatol (2007) 1.05
Air exposure induced squamous metaplasia of human limbal epithelium. Invest Ophthalmol Vis Sci (2008) 0.95
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Co-factors of LIM domains (Clims/Ldb/Nli) regulate corneal homeostasis and maintenance of hair follicle stem cells. Dev Biol (2007) 0.90
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Localisation of epithelial cells capable of holoclone formation in vitro and direct interaction with stromal cells in the native human limbal crypt. PLoS One (2014) 0.88
In search of the Golden Fleece: unraveling principles of morphogenesis by studying the integrative biology of skin appendages. Integr Biol (Camb) (2011) 0.86
Overexpression of Pax6 in mouse cornea directly alters corneal epithelial cells: changes in immune function, vascularization, and differentiation. Invest Ophthalmol Vis Sci (2011) 0.85
Aberrant expression of a beta-catenin gain-of-function mutant induces hyperplastic transformation in the mouse cornea. J Cell Sci (2010) 0.84
An ideal society? Neighbors of diverse origins interact to create and maintain complex mini-organs in the skin. PLoS Biol (2005) 0.84
Importance of the stem cell microenvironment for ophthalmological cell-based therapy. World J Stem Cells (2015) 0.82
The homeodomain transcription factor PITX2 is required for specifying correct cell fates and establishing angiogenic privilege in the developing cornea. Dev Dyn (2014) 0.82
Reconstruction of damaged cornea by autologous transplantation of epidermal adult stem cells. Mol Vis (2008) 0.82
Pax6 downregulation mediates abnormal lineage commitment of the ocular surface epithelium in aqueous-deficient dry eye disease. PLoS One (2013) 0.81
Epidermal differentiation and loss of clonal growth potential of human limbal basal epithelial progenitor cells during intrastromal invasion. Invest Ophthalmol Vis Sci (2011) 0.81
Role of Pnn in alternative splicing of a specific subset of lncRNAs of the corneal epithelium. Mol Vis (2014) 0.80
Air exposure induced characteristics of dry eye in conjunctival tissue culture. PLoS One (2014) 0.78
ES micro-environment enhances stemness and inhibits apoptosis in human limbal stem cells via the maintenance of telomerase activity. PLoS One (2013) 0.78
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K14 + Compound niches are present on the mouse cornea early after birth and expand after debridement wounds. Dev Dyn (2015) 0.77
Reconstruction of rabbit urethral epithelium with skin keratinocytes. Acta Naturae (2015) 0.75
Foxc1 and Foxc2 in the Neural Crest Are Required for Ocular Anterior Segment Development. Invest Ophthalmol Vis Sci (2017) 0.75
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Genetic correction of stem cells in the treatment of inherited diseases and focus on xeroderma pigmentosum. Int J Mol Sci (2013) 0.75
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De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin. Cell (1998) 7.95
Involvement of follicular stem cells in forming not only the follicle but also the epidermis. Cell (2000) 6.93
WNT signals are required for the initiation of hair follicle development. Dev Cell (2002) 6.63
Morphogenesis and renewal of hair follicles from adult multipotent stem cells. Cell (2001) 6.37
Differentiation-related expression of a major 64K corneal keratin in vivo and in culture suggests limbal location of corneal epithelial stem cells. J Cell Biol (1986) 5.96
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Turning brain into blood: a hematopoietic fate adopted by adult neural stem cells in vivo. Science (1999) 5.22
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Oligodendrocyte precursor cells reprogrammed to become multipotential CNS stem cells. Science (2000) 4.65
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Wnt signaling maintains the hair-inducing activity of the dermal papilla. Genes Dev (2000) 2.77
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Autologous fibrin-cultured limbal stem cells permanently restore the corneal surface of patients with total limbal stem cell deficiency. Transplantation (2001) 1.60
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Cultured dermal papilla cells induce follicle formation and hair growth by transdifferentiation of an adult epidermis. Development (1992) 1.29
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Modulation of BMP signaling by noggin is required for induction of the secondary (nontylotrich) hair follicles. J Invest Dermatol (2002) 1.25
Integument pattern formation involves genetic and epigenetic controls: feather arrays simulated by digital hormone models. Int J Dev Biol (2004) 1.24
Corneal epithelial stem cells: past, present, and future. J Investig Dermatol Symp Proc (2004) 1.22
Pax genes and eye organogenesis. Curr Opin Genet Dev (2002) 1.20
Adult corneal epithelium basal cells possess the capacity to activate epidermal, pilosebaceous and sweat gland genetic programs in response to embryonic dermal stimuli. Development (2000) 1.20
A developmental conundrum: a stabilized form of beta-catenin lacking the transcriptional activation domain triggers features of hair cell fate in epidermal cells and epidermal cell fate in hair follicle cells. J Cell Biol (2002) 1.19
The stem cell compartment in human interfollicular epidermis. J Dermatol Sci (2002) 1.18
Cell differentiation and cell fate during urodele tail and limb regeneration. Curr Opin Genet Dev (2003) 1.13
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Stem-cell "plasticity": befuddled by the muddle. Curr Opin Hematol (2003) 1.05
PAX6 and congenital eye malformations. Pediatr Res (2003) 1.04
Cell fusion: an alternative to stem cell plasticity and its therapeutic implications. Curr Opin Genet Dev (2003) 1.00
Corneal epithelium-specific mouse keratin K12 promoter. Exp Eye Res (1999) 0.99
Keratin expression during normal epidermal differentiation. Curr Probl Dermatol (1983) 0.96
Further proof of the plasticity of adult stem cells and their role in tissue repair. J Cell Biol (2003) 0.94
Appearance of the keratin pair K3/K12 during embryonic and adult corneal epithelial differentiation in the chick and in the rabbit. Cell Differ Dev (1990) 0.90
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The different steps of skin formation in vertebrates. Int J Dev Biol (2004) 0.90
Nuclear localization of beta-catenin in the hair matrix cells and differentiated keratinocytes. J Dermatol Sci (2001) 0.80
Neural stem cells: plasticity and their transdifferentiation potential. Cells Tissues Organs (2002) 0.80
Plastic adult stem cells: will they graduate from the school of hard knocks? J Cell Sci (2003) 0.79
Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases. Cancer Cell (2011) 11.44
N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO. Nat Chem Biol (2011) 5.96
Role of detection method in predicting breast cancer survival: analysis of randomized screening trials. J Natl Cancer Inst (2005) 4.01
Extra-embryonic function of Rb is essential for embryonic development and viability. Nature (2003) 3.92
Vasculotropic, paracrine actions of infused mesenchymal stem cells are important to the recovery from acute kidney injury. Am J Physiol Renal Physiol (2007) 3.54
Gene transfer into genomes of human cells by the sleeping beauty transposon system. Mol Ther (2003) 3.34
Pediatric mastocytosis is a clonal disease associated with D816V and other activating c-KIT mutations. J Invest Dermatol (2009) 2.94
Is breast cancer survival improving? Cancer (2004) 2.73
Pax6 is a human neuroectoderm cell fate determinant. Cell Stem Cell (2010) 2.46
Single-spike detection in vitro and in vivo with a genetic Ca2+ sensor. Nat Methods (2008) 2.44
Activation of the Akt/mammalian target of rapamycin/4E-BP1 pathway by ErbB2 overexpression predicts tumor progression in breast cancers. Clin Cancer Res (2004) 2.28
Oncogenic properties of PPM1D located within a breast cancer amplification epicenter at 17q23. Nat Genet (2002) 2.23
Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease. Nat Genet (2012) 2.17
Bcl-2 and Bcl-xL play important roles in the crosstalk between autophagy and apoptosis. FEBS J (2010) 2.13
Ascorbic acid enhances Tet-mediated 5-methylcytosine oxidation and promotes DNA demethylation in mammals. J Am Chem Soc (2013) 1.90
A cytochrome C oxidase model catalyzes oxygen to water reduction under rate-limiting electron flux. Science (2007) 1.84
DACH1 is a cell fate determination factor that inhibits cyclin D1 and breast tumor growth. Mol Cell Biol (2006) 1.80
Response of a KIT-positive extra-abdominal fibromatosis to imatinib mesylate and KIT genetic analysis. J Natl Cancer Inst (2006) 1.80
Bax regulates primary necrosis through mitochondrial dynamics. Proc Natl Acad Sci U S A (2012) 1.80
Lifetime prevalence of mood and anxiety disorders in fragile X premutation carriers. J Clin Psychiatry (2010) 1.79
Rb function in extraembryonic lineages suppresses apoptosis in the CNS of Rb-deficient mice. Proc Natl Acad Sci U S A (2003) 1.74
Effects of berberine on glucose metabolism in vitro. Metabolism (2002) 1.74
The nuclear hormone receptor Coup-TFII is required for the initiation and early maintenance of Prox1 expression in lymphatic endothelial cells. Genes Dev (2010) 1.73
Optical recording of neuronal activity with a genetically-encoded calcium indicator in anesthetized and freely moving mice. Front Neural Circuits (2010) 1.71
Reciprocal regulation of Akt and Oct4 promotes the self-renewal and survival of embryonal carcinoma cells. Mol Cell (2012) 1.63
Enhanced radical scavenging activity by antioxidant-functionalized gold nanoparticles: a novel inspiration for development of new artificial antioxidants. Free Radic Biol Med (2007) 1.59
Pluripotency can be rapidly and efficiently induced in human amniotic fluid-derived cells. Hum Mol Genet (2009) 1.54
Prognostic factors and treatment of patients with T-cell non-Hodgkin lymphoma: the M. D. Anderson Cancer Center experience. Cancer (2005) 1.53
Left atrial regional phasic strain, strain rate and velocity by speckle-tracking echocardiography: normal values and effects of aging in a large group of normal subjects. Int J Cardiol (2013) 1.52
DACH1 inhibits transforming growth factor-beta signaling through binding Smad4. J Biol Chem (2003) 1.47
Characterizing the viscoelastic properties of thin hydrogel-based constructs for tissue engineering applications. J R Soc Interface (2005) 1.47
Dyssynchronous pacing triggers endothelial-mesenchymal transition through heterogeneity of mechanical stretch in a canine model. Circ J (2014) 1.41
Phosphorylation of tau antagonizes apoptosis by stabilizing beta-catenin, a mechanism involved in Alzheimer's neurodegeneration. Proc Natl Acad Sci U S A (2007) 1.41
Autologous and allogeneic marrow stromal cells are safe and effective for the treatment of acute kidney injury. Stem Cells Dev (2009) 1.41
Plasma catecholamine release-inhibitory peptide catestatin in patients with essential hypertension. J Cardiovasc Med (Hagerstown) (2011) 1.41
Berberine stimulates glucose transport through a mechanism distinct from insulin. Metabolism (2007) 1.40
Treatment effects of selegiline transdermal system on symptoms of major depressive disorder: a meta-analysis of short-term, placebo-controlled, efficacy trials. Psychopharmacol Bull (2007) 1.40
Insertion of a Pax6 consensus binding site into the alphaA-crystallin promoter acts as a lens epithelial cell enhancer in transgenic mice. Invest Ophthalmol Vis Sci (2004) 1.40
Mapping Cu(II) binding sites in prion proteins by diethyl pyrocarbonate modification and matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometric footprinting. J Biol Chem (2001) 1.39
Study of gemcitabine-sensitive/resistant cancer cells by cell cloning and synchrotron FTIR microspectroscopy. Cytometry A (2014) 1.38
Transcriptome analysis of early organogenesis in human embryos. Dev Cell (2010) 1.37
Glycine metabolism in animals and humans: implications for nutrition and health. Amino Acids (2013) 1.36
Bioluminescence imaging to monitor the in vivo distribution of administered mesenchymal stem cells in acute kidney injury. Am J Physiol Renal Physiol (2008) 1.36
Polymorphisms of KDR gene are associated with coronary heart disease. J Am Coll Cardiol (2007) 1.35
The public health impact of coccidioidomycosis in Arizona and California. Int J Environ Res Public Health (2011) 1.35
Development of the mammalian lymphatic vasculature. J Clin Invest (2014) 1.34
Gain-of-function mutations in the extracellular domain of KIT are common in canine mast cell tumors. Mol Cancer Res (2008) 1.31
Prognostic significance of phosphorylated P38 mitogen-activated protein kinase and HER-2 expression in lymph node-positive breast carcinoma. Cancer (2004) 1.30
FLEXIBLE CULM 1 encoding a cinnamyl-alcohol dehydrogenase controls culm mechanical strength in rice. Plant Mol Biol (2008) 1.29
Carbon nanofibers prepared via electrospinning. Adv Mater (2012) 1.28
Optical coherence tomography: real-time imaging of bronchial airways microstructure and detection of inflammatory/neoplastic morphologic changes. Clin Cancer Res (2006) 1.27
The identification of potential factors associated with the development of type 2 diabetes: a quantitative proteomics approach. Mol Cell Proteomics (2008) 1.27
Characterization of the complete mitochondrial genome of the giant silkworm moth, Eriogyna pyretorum (Lepidoptera: Saturniidae). Int J Biol Sci (2009) 1.24
Change in tumor cellularity of breast carcinoma after neoadjuvant chemotherapy as a variable in the pathologic assessment of response. Cancer (2004) 1.22
Gab2-mediated signaling promotes melanoma metastasis. Am J Pathol (2009) 1.21
PRC17, a novel oncogene encoding a Rab GTPase-activating protein, is amplified in prostate cancer. Cancer Res (2002) 1.20
Regulation of gene expression by Pax6 in ocular cells: a case of tissue-preferred expression of crystallins in lens. Int J Dev Biol (2004) 1.20
CD44 expression is associated with increased survival in node-negative invasive breast carcinoma. Clin Cancer Res (2005) 1.19
Identification of pax6-dependent gene regulatory networks in the mouse lens. PLoS One (2009) 1.19
Hair follicle stem cells. J Investig Dermatol Symp Proc (2003) 1.19
A functional nitric oxide reductase model. Proc Natl Acad Sci U S A (2008) 1.14
Functional interactions between alternatively spliced forms of Pax6 in crystallin gene regulation and in haploinsufficiency. Nucleic Acids Res (2004) 1.14
CD25 expression is correlated with histological grade and response to denileukin diftitox in cutaneous T-cell lymphoma. J Invest Dermatol (2006) 1.12
Stk40 links the pluripotency factor Oct4 to the Erk/MAPK pathway and controls extraembryonic endoderm differentiation. Proc Natl Acad Sci U S A (2010) 1.12
JAK2/STAT3 pathway is involved in the early stage of adipogenesis through regulating C/EBPβ transcription. J Cell Biochem (2011) 1.12
Predictive value of serum CEA, CA19-9 and CA72.4 in early diagnosis of recurrence after radical resection of gastric cancer. Hepatogastroenterology (2012) 1.09
Dietary requirements of "nutritionally non-essential amino acids" by animals and humans. Amino Acids (2012) 1.09
Cell autonomous roles for AP-2alpha in lens vesicle separation and maintenance of the lens epithelial cell phenotype. Dev Dyn (2008) 1.08
Ordered mesoporous black TiO(2) as highly efficient hydrogen evolution photocatalyst. J Am Chem Soc (2014) 1.08
Identification of the transmembrane metal binding site in Cu+-transporting PIB-type ATPases. J Biol Chem (2004) 1.08
High frequency of submicroscopic hemizygous deletion is a major mechanism of loss of expression of PTEN in uveal melanoma. J Clin Oncol (2005) 1.08
Ginsenoside Rb1 stimulates glucose uptake through insulin-like signaling pathway in 3T3-L1 adipocytes. J Endocrinol (2008) 1.08
Fibroblast growth factor receptor 1 (Fgfr1) is not essential for lens fiber differentiation in mice. Mol Vis (2006) 1.08
Laparoscopic choledochal cyst excision, hepaticojejunostomy, and extracorporeal Roux-en-Y anastomosis: a technical skill and intermediate-term report in 62 cases. Surg Endosc (2010) 1.08
Molecular mechanisms controlling dorsal dermis generation from the somitic dermomyotome. Int J Dev Biol (2004) 1.07
Case-control cohort study of patients' perceptions of disability in mastocytosis. PLoS One (2008) 1.07
Plasma uric acid and hypertension in a Chinese community: prospective study and metaanalysis. Clin Chem (2009) 1.07
A comparative cDNA microarray analysis reveals a spectrum of genes regulated by Pax6 in mouse lens. Genes Cells (2002) 1.06
Ixodes scapularis JAK-STAT pathway regulates tick antimicrobial peptides, thereby controlling the agent of human granulocytic anaplasmosis. J Infect Dis (2012) 1.06
ErbB2 overexpression correlates with increased expression of vascular endothelial growth factors A, C, and D in human breast carcinoma. Cancer (2002) 1.06
Cytoprotective doses of erythropoietin or carbamylated erythropoietin have markedly different procoagulant and vasoactive activities. Proc Natl Acad Sci U S A (2006) 1.05
Design and synthesis of potent inhibitors of beta-ketoacyl-acyl carrier protein synthase III (FabH) as potential antibacterial agents. Eur J Med Chem (2010) 1.04
TLP-1 is an asymmetric cell fate determinant that responds to Wnt signals and controls male tail tip morphogenesis in C. elegans. Development (2002) 1.03
Beta4 integrin subunit gene expression correlates with tumor size and nuclear grade in early breast cancer. Mod Pathol (2005) 1.03
Contractile dysfunction in hypertrophied hearts with deficient insulin receptor signaling: possible role of reduced capillary density. J Mol Cell Cardiol (2005) 1.03
Combination of carotid intima-media thickness and plaque for better predicting risk of ischaemic cardiovascular events. Heart (2011) 1.03
TNFα-induced up-regulation of miR-155 inhibits adipogenesis by down-regulating early adipogenic transcription factors. Biochem Biophys Res Commun (2011) 1.02
Jun activation domain binding protein 1 expression is associated with low p27(Kip1)levels in node-negative breast cancer. Clin Cancer Res (2003) 1.02
Catalytic reduction of O2 by cytochrome C using a synthetic model of cytochrome C oxidase. J Am Chem Soc (2009) 1.02
BMP2 and BMP7 play antagonistic roles in feather induction. Development (2008) 1.01
Strain and sex differences in anxiety-like and social behaviors in C57BL/6J and BALB/cJ mice. Exp Anim (2011) 1.01
Transformation of amnion epithelium into skin and hair follicles. Differentiation (2004) 1.01
The complete nucleotide sequence of the mitochondrial genome of the cabbage butterfly, Artogeia melete (Lepidoptera: Pieridae). Acta Biochim Biophys Sin (Shanghai) (2009) 1.01
Germline-competent mouse-induced pluripotent stem cell lines generated on human fibroblasts without exogenous leukemia inhibitory factor. PLoS One (2009) 1.01
Correlation of metastasis related gene expression and relapse-free survival in patients with locally advanced bladder cancer treated with cystectomy and chemotherapy. J Urol (2004) 1.00
Ginsenoside Rb1 promotes adipogenesis in 3T3-L1 cells by enhancing PPARgamma2 and C/EBPalpha gene expression. Life Sci (2006) 1.00
LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation. Mol Cell (2012) 1.00
Lipid-lowering and antioxidant activities of Jiang-Zhi-Ning in Traditional Chinese Medicine. J Ethnopharmacol (2011) 1.00
Activation of ERK-p53 and ERK-mediated phosphorylation of Bcl-2 are involved in autophagic cell death induced by the c-Met inhibitor SU11274 in human lung cancer A549 cells. J Pharmacol Sci (2012) 0.99
Serum CRP levels are equally elevated in newly diagnosed type 2 diabetes and impaired glucose tolerance and related to adiponectin levels and insulin sensitivity. Diabetes Res Clin Pract (2005) 0.99