Cortical lesions in multiple sclerosis: combined postmortem MR imaging and histopathology.

PubWeight™: 2.07‹?› | Rank: Top 2%

🔗 View Article (PMID 15760868)

Published in AJNR Am J Neuroradiol on March 01, 2005

Authors

Jeroen J G Geurts1, Lars Bö, Petra J W Pouwels, Jonas A Castelijns, Chris H Polman, Frederik Barkhof

Author Affiliations

1: Department of Radiology, VU University Medical Center, Amsterdam, the Netherlands.

Articles citing this

In vivo imaging of cortical pathology in multiple sclerosis using ultra-high field MRI. Neurology (2009) 1.64

Unified approach for multiple sclerosis lesion segmentation on brain MRI. Ann Biomed Eng (2006) 1.58

Cortical atrophy is relevant in multiple sclerosis at clinical onset. J Neurol (2007) 1.51

Cortical lesions in multiple sclerosis. Nat Rev Neurol (2010) 1.47

Improved in vivo detection of cortical lesions in multiple sclerosis using double inversion recovery MR imaging at 3 Tesla. Eur Radiol (2010) 1.41

3D MPRAGE improves classification of cortical lesions in multiple sclerosis. Mult Scler (2008) 1.39

Magnetic resonance spectroscopy in the monitoring of multiple sclerosis. J Neuroimaging (2005) 1.36

Multi-contrast, isotropic, single-slab 3D MR imaging in multiple sclerosis. Eur Radiol (2008) 1.22

Proton magnetic resonance spectroscopy in multiple sclerosis. Neuroimaging Clin N Am (2009) 1.17

Seizures in patients with multiple sclerosis: epidemiology, pathophysiology and management. CNS Drugs (2009) 1.14

High-resolution phased-array MRI of the human brain at 7 tesla: initial experience in multiple sclerosis patients. J Neuroimaging (2009) 1.09

Quantification and clinical relevance of brain atrophy in multiple sclerosis: a review. J Neurol (2009) 1.08

Clinically feasible MTR is sensitive to cortical demyelination in MS. Neurology (2012) 1.07

Does high-field MR imaging improve cortical lesion detection in multiple sclerosis? J Neurol (2008) 1.05

Clinical trials in progressive multiple sclerosis: lessons learned and future perspectives. Lancet Neurol (2015) 1.05

Extensive cortical inflammation is associated with epilepsy in multiple sclerosis. J Neurol (2008) 1.03

Gray matter imaging in multiple sclerosis: what have we learned? BMC Neurol (2011) 1.03

Diffusion tensor imaging in acute optic neuropathies: predictor of clinical outcomes. Arch Neurol (2011) 1.02

Intracortical lesions by 3T magnetic resonance imaging and correlation with cognitive impairment in multiple sclerosis. Mult Scler (2011) 1.01

Normal-appearing white and grey matter damage in MS. A volumetric and diffusion tensor MRI study at 3.0 Tesla. J Neurol (2007) 1.01

Postmortem magnetic resonance imaging to guide the pathologic cut: individualized, 3-dimensionally printed cutting boxes for fixed brains. J Neuropathol Exp Neurol (2014) 0.99

An animal model of cortical and callosal pathology in multiple sclerosis. Brain Pathol (2010) 0.97

Increased radial diffusivity in spinal cord lesions in neuromyelitis optica compared with multiple sclerosis. Mult Scler (2012) 0.97

Focal cortical lesion detection in multiple sclerosis: 3 Tesla DIR versus 7 Tesla FLASH-T2. J Magn Reson Imaging (2011) 0.97

Clinical correlates of grey matter pathology in multiple sclerosis. BMC Neurol (2012) 0.94

T2 lesion location really matters: a 10 year follow-up study in primary progressive multiple sclerosis. J Neurol Neurosurg Psychiatry (2010) 0.94

Exogenous leukemia inhibitory factor stimulates oligodendrocyte progenitor cell proliferation and enhances hippocampal remyelination. J Neurosci (2012) 0.94

Cognitive dysfunction in multiple sclerosis. Front Neurol (2012) 0.94

Multimodal white matter imaging to investigate reduced fractional anisotropy and its age-related decline in schizophrenia. Psychiatry Res (2014) 0.93

Fast whole-brain three-dimensional macromolecular proton fraction mapping in multiple sclerosis. Radiology (2014) 0.93

Grey matter damage in multiple sclerosis: a pathology perspective. Prion (2013) 0.93

Imaging cadavers: cold FLAIR and noninvasive brain thermometry using CSF diffusion. Magn Reson Med (2008) 0.91

Magnetisation transfer ratio in the normal appearing white matter predicts progression of disability over 1 year in early primary progressive multiple sclerosis. J Neurol Neurosurg Psychiatry (2007) 0.91

Jacobian integration method increases the statistical power to measure gray matter atrophy in multiple sclerosis. Neuroimage Clin (2013) 0.91

Quantitative magnetic resonance imaging of cortical multiple sclerosis pathology. Mult Scler Int (2012) 0.90

Axonal damage in multiple sclerosis. Mt Sinai J Med (2011) 0.87

Ultrahigh field MRI in clinical neuroimmunology: a potential contribution to improved diagnostics and personalised disease management. EPMA J (2015) 0.86

Magnetization transfer ratio abnormalities reflect clinically relevant grey matter damage in multiple sclerosis. Mult Scler (2009) 0.85

Neuroimaging in multiple sclerosis: neurotherapeutic implications. Neurotherapeutics (2011) 0.85

Multisequence-imaging protocols to detect cortical lesions of patients with multiple sclerosis: observations from a post-mortem 3 Tesla imaging study. J Neurol Sci (2009) 0.85

Advances in understanding gray matter pathology in multiple sclerosis: are we ready to redefine disease pathogenesis? BMC Neurol (2012) 0.84

Thalamic-hippocampal-prefrontal disruption in relapsing-remitting multiple sclerosis. Neuroimage Clin (2014) 0.83

Microstructural changes in the striatum and their impact on motor and neuropsychological performance in patients with multiple sclerosis. PLoS One (2014) 0.83

Iron in Multiple Sclerosis and Its Noninvasive Imaging with Quantitative Susceptibility Mapping. Int J Mol Sci (2016) 0.82

Perfusion reduction in the absence of structural differences in cognitively impaired versus unimpaired RRMS patients. Mult Scler (2016) 0.82

Prevalence of grey matter pathology in early multiple sclerosis assessed by magnetization transfer ratio imaging. PLoS One (2011) 0.81

A 3-year diffusion tensor MRI study of grey matter damage progression during the earliest clinical stage of MS. J Neurol (2008) 0.81

Comparison of double inversion recovery and conventional magnetic resonance brain imaging in patients with multiple sclerosis and relations with disease disability. Neuroradiol J (2013) 0.81

Progressive multiple sclerosis and gray matter pathology: an MRI perspective. Mt Sinai J Med (2011) 0.81

Oligodendroglia in cortical multiple sclerosis lesions decrease with disease progression, but regenerate after repeated experimental demyelination. Acta Neuropathol (2014) 0.81

Grey matter lesions in MS: from histology to clinical implications. Prion (2012) 0.81

The Parallel Analysis of Phase Sensitive Inversion Recovery (PSIR) and Double Inversion Recovery (DIR) Images Significantly Improves the Detection of Cortical Lesions in Multiple Sclerosis (MS) since Clinical Onset. PLoS One (2015) 0.80

Grey matter magnetization transfer ratio independently correlates with neurological deficit in secondary progressive multiple sclerosis. J Neurol (2009) 0.80

Effects of formalin fixation on magnetic resonance indices in multiple sclerosis cortical gray matter. J Magn Reson Imaging (2010) 0.80

Expansion of CD27high plasmablasts in transverse myelitis patients that utilize VH4 and JH6 genes and undergo extensive somatic hypermutation. Genes Immun (2013) 0.80

Gray Matter Pathology in MS: Neuroimaging and Clinical Correlations. Mult Scler Int (2013) 0.80

Focal and diffuse cortical degenerative changes in a marmoset model of multiple sclerosis. Mult Scler (2010) 0.80

Imaging as an Outcome Measure in Multiple Sclerosis. Neurotherapeutics (2016) 0.79

Use of Magnetic Resonance Imaging as Well as Clinical Disease Activity in the Clinical Classification of Multiple Sclerosis and Assessment of Its Course: A Report from an International CMSC Consensus Conference, March 5-7, 2010. Int J MS Care (2012) 0.79

Natalizumab prevents the accumulation of cortical lesions in relapsing remitting multiple sclerosis: a preliminary report. Neurol Sci (2011) 0.78

Immunopathogenesis of multiple sclerosis. Ann Indian Acad Neurol (2009) 0.78

Bimonthly Evolution of Cortical Atrophy in Early Relapsing-Remitting Multiple Sclerosis over 2 Years: A Longitudinal Study. Mult Scler Int (2013) 0.77

Advanced MRI and staging of multiple sclerosis lesions. Nat Rev Neurol (2016) 0.77

DIR-visible grey matter lesions and atrophy in multiple sclerosis: partners in crime? J Neurol Neurosurg Psychiatry (2015) 0.77

Disease-modifying drugs reduce cortical lesion accumulation and atrophy progression in relapsing-remitting multiple sclerosis: results from a 48-month extension study. Mult Scler Int (2015) 0.76

Detection and quantification of regional cortical gray matter damage in multiple sclerosis utilizing gradient echo MRI. Neuroimage Clin (2015) 0.76

Delineation of cortical pathology in multiple sclerosis using multi-surface magnetization transfer ratio imaging. Neuroimage Clin (2016) 0.76

Reliability of cortical lesion detection on double inversion recovery MRI applying the MAGNIMS-Criteria in multiple sclerosis patients within a 16-months period. PLoS One (2017) 0.75

Unilateral olfactory sensitivity in multiple sclerosis. Physiol Behav (2016) 0.75

Phase-Sensitive Inversion-Recovery MRI Improves Longitudinal Cortical Lesion Detection in Progressive MS. PLoS One (2016) 0.75

Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination. J Vis Exp (2016) 0.75

Spring cleaning: time to rethink imaging research lines in MS? J Neurol (2016) 0.75

Sativex in the management of multiple sclerosis-related spasticity: role of the corticospinal modulation. Neural Plast (2015) 0.75

Ex vivo tissue imaging for radiology-pathology correlation: a pilot study with a small bore 7-T MRI in a rare pigmented ganglioglioma exhibiting complex MR signal characteristics associated with melanin and hemosiderin. J Med Imaging (Bellingham) (2017) 0.75

Altered signal intensity of active enhancing inflammatory lesions using post-contrast double inversion recovery MR sequence. Eur Radiol (2016) 0.75

7T MRI Visualization of Cortical Lesions in Adolescents and Young Adults with Pediatric-Onset Multiple Sclerosis. J Neuroimaging (2017) 0.75

Articles by these authors

Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis. N Engl J Med (2010) 13.82

Oral fingolimod (FTY720) for relapsing multiple sclerosis. N Engl J Med (2006) 7.18

Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration. Lancet Neurol (2013) 6.18

Evaluation of patients treated with natalizumab for progressive multifocal leukoencephalopathy. N Engl J Med (2006) 5.20

Further Implications of Off-Label Use of Acetazolamide in the Management of Moyamoya Disease in Japan: Response. Radiology (2017) 4.99

T helper type 1 and 17 cells determine efficacy of interferon-beta in multiple sclerosis and experimental encephalomyelitis. Nat Med (2010) 4.78

Altered resting state networks in mild cognitive impairment and mild Alzheimer's disease: an fMRI study. Hum Brain Mapp (2005) 4.11

PML in a patient treated with dimethyl fumarate from a compounding pharmacy. N Engl J Med (2013) 4.02

Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. Hum Mol Genet (2008) 3.93

Pathway and network-based analysis of genome-wide association studies in multiple sclerosis. Hum Mol Genet (2009) 3.92

Ocrelizumab in relapsing-remitting multiple sclerosis: a phase 2, randomised, placebo-controlled, multicentre trial. Lancet (2011) 3.76

Efficacy and safety of oral fumarate in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study. Lancet (2008) 3.68

Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. Ann Neurol (2011) 3.52

MRI criteria for multiple sclerosis in patients presenting with clinically isolated syndromes: a multicentre retrospective study. Lancet Neurol (2007) 3.47

Long-term effect of early treatment with interferon beta-1b after a first clinical event suggestive of multiple sclerosis: 5-year active treatment extension of the phase 3 BENEFIT trial. Lancet Neurol (2009) 3.42

Effect of early versus delayed interferon beta-1b treatment on disability after a first clinical event suggestive of multiple sclerosis: a 3-year follow-up analysis of the BENEFIT study. Lancet (2007) 3.29

Comparison of fingolimod with interferon beta-1a in relapsing-remitting multiple sclerosis: a randomised extension of the TRANSFORMS study. Lancet Neurol (2011) 3.16

Comparison of subcutaneous interferon beta-1a with glatiramer acetate in patients with relapsing multiple sclerosis (the REbif vs Glatiramer Acetate in Relapsing MS Disease [REGARD] study): a multicentre, randomised, parallel, open-label trial. Lancet Neurol (2008) 3.01

Effect of natalizumab on clinical and radiological disease activity in multiple sclerosis: a retrospective analysis of the Natalizumab Safety and Efficacy in Relapsing-Remitting Multiple Sclerosis (AFFIRM) study. Lancet Neurol (2009) 2.82

Mechanism of amyloid removal in patients with Alzheimer disease treated with gantenerumab. Arch Neurol (2011) 2.75

Performance of immuno-positron emission tomography with zirconium-89-labeled chimeric monoclonal antibody U36 in the detection of lymph node metastases in head and neck cancer patients. Clin Cancer Res (2006) 2.71

Chronic cerebrospinal venous insufficiency and multiple sclerosis. Ann Neurol (2010) 2.63

Small vessel disease and general cognitive function in nondisabled elderly: the LADIS study. Stroke (2005) 2.59

Progression of white matter hyperintensities and incidence of new lacunes over a 3-year period: the Leukoaraiosis and Disability study. Stroke (2008) 2.57

Changes in white matter as determinant of global functional decline in older independent outpatients: three year follow-up of LADIS (leukoaraiosis and disability) study cohort. BMJ (2009) 2.51

Intracortical lesions in multiple sclerosis: improved detection with 3D double inversion-recovery MR imaging. Radiology (2005) 2.47

Tumefactive multiple sclerosis lesions under fingolimod treatment. Neurology (2012) 2.44

Heterogeneity of small vessel disease: a systematic review of MRI and histopathology correlations. J Neurol Neurosurg Psychiatry (2010) 2.44

MRI and the diagnosis of multiple sclerosis: expanding the concept of "no better explanation". Lancet Neurol (2006) 2.44

Measurement of atrophy in multiple sclerosis: pathological basis, methodological aspects and clinical relevance. Brain (2002) 2.30

Homogeneity of active demyelinating lesions in established multiple sclerosis. Ann Neurol (2008) 2.29

Magnetic resonance imaging pattern recognition in hypomyelinating disorders. Brain (2010) 2.19

Loss of 'small-world' networks in Alzheimer's disease: graph analysis of FMRI resting-state functional connectivity. PLoS One (2010) 2.12

Clinically isolated syndromes suggestive of multiple sclerosis, part I: natural history, pathogenesis, diagnosis, and prognosis. Lancet Neurol (2005) 2.10

MRI in multiple sclerosis: current status and future prospects. Lancet Neurol (2008) 2.08

Outcome of patients with early stage oral cancer managed by an observation strategy towards the N0 neck using ultrasound guided fine needle aspiration cytology: No survival difference as compared to elective neck dissection. Oral Oncol (2012) 2.08

Grey matter volume in a large cohort of MS patients: relation to MRI parameters and disability. Mult Scler (2011) 2.07

Lack of association between antimyelin antibodies and progression to multiple sclerosis. N Engl J Med (2007) 2.06

Safety, anxiety and natalizumab continuation in JC virus-seropositive MS patients. Mult Scler (2013) 2.04

Grey matter pathology in multiple sclerosis. Lancet Neurol (2008) 1.97

Interferon beta-1a for brain tissue loss in patients at presentation with syndromes suggestive of multiple sclerosis: a randomised, double-blind, placebo-controlled trial. Lancet (2004) 1.93

Therapeutic IgG4 antibodies engage in Fab-arm exchange with endogenous human IgG4 in vivo. Nat Biotechnol (2009) 1.90

Impact of white matter hyperintensities scoring method on correlations with clinical data: the LADIS study. Stroke (2006) 1.88

Health-related quality of life in multiple sclerosis: effects of natalizumab. Ann Neurol (2007) 1.88

Intravenous immunoglobulin for treatment of mild-to-moderate Alzheimer's disease: a phase 2, randomised, double-blind, placebo-controlled, dose-finding trial. Lancet Neurol (2013) 1.84

Precuneus atrophy in early-onset Alzheimer's disease: a morphometric structural MRI study. Neuroradiology (2007) 1.80

Comparison of two dosing frequencies of subcutaneous interferon beta-1a in patients with a first clinical demyelinating event suggestive of multiple sclerosis (REFLEX): a phase 3 randomised controlled trial. Lancet Neurol (2011) 1.79

Imaging markers for Alzheimer disease: which vs how. Neurology (2013) 1.76

The pathology of multiple sclerosis is location-dependent: no significant complement activation is detected in purely cortical lesions. J Neuropathol Exp Neurol (2005) 1.76

Unusual variants of Alexander's disease. Ann Neurol (2005) 1.76

On the etiology of incident brain lacunes: longitudinal observations from the LADIS study. Stroke (2008) 1.75

Clinico-pathological evidence that axonal loss underlies disability in progressive multiple sclerosis. Mult Scler (2010) 1.72

Association between pathological and MRI findings in multiple sclerosis. Lancet Neurol (2012) 1.70

Radiation dosimetry of 89Zr-labeled chimeric monoclonal antibody U36 as used for immuno-PET in head and neck cancer patients. J Nucl Med (2009) 1.68

Assessment of JC virus DNA in blood and urine from natalizumab-treated patients. Ann Neurol (2010) 1.68

No association of abnormal cranial venous drainage with multiple sclerosis: a magnetic resonance venography and flow-quantification study. J Neurol Neurosurg Psychiatry (2010) 1.68

Improved detection of active multiple sclerosis lesions: 3D subtraction imaging. Radiology (2010) 1.68

Accelerated aging, decreased white matter integrity, and associated neuropsychological dysfunction 25 years after pediatric lymphoid malignancies. J Clin Oncol (2013) 1.67

Whole-brain atrophy rate and CSF biomarker levels in MCI and AD: a longitudinal study. Neurobiol Aging (2008) 1.67

Structural magnetic resonance imaging in the practical assessment of dementia: beyond exclusion. Lancet Neurol (2002) 1.64

Microbleeds do not affect rate of cognitive decline in Alzheimer disease. Neurology (2012) 1.62

Overdiagnosis of multiple sclerosis and magnetic resonance imaging criteria. Ann Neurol (2005) 1.61

Steps to standardization and validation of hippocampal volumetry as a biomarker in clinical trials and diagnostic criterion for Alzheimer's disease. Alzheimers Dement (2011) 1.59

Model-free group analysis shows altered BOLD FMRI networks in dementia. Hum Brain Mapp (2009) 1.59

Patients with Alzheimer disease with multiple microbleeds: relation with cerebrospinal fluid biomarkers and cognition. Stroke (2009) 1.57

Location of brain lesions predicts conversion of clinically isolated syndromes to multiple sclerosis. Neurology (2012) 1.57

Injury markers but not amyloid markers are associated with rapid progression from mild cognitive impairment to dementia in Alzheimer's disease. J Alzheimers Dis (2012) 1.57

A new leukoencephalopathy with brainstem and spinal cord involvement and high lactate. Ann Neurol (2003) 1.57

White matter tract integrity in aging and Alzheimer's disease. Hum Brain Mapp (2009) 1.57

Whole-brain atrophy rate and cognitive decline: longitudinal MR study of memory clinic patients. Radiology (2008) 1.56

Remyelinated lesions in multiple sclerosis: magnetic resonance image appearance. Arch Neurol (2003) 1.55

Resting-state fMRI changes in Alzheimer's disease and mild cognitive impairment. Neurobiol Aging (2011) 1.54

Diffusion changes predict cognitive and functional outcome: the LADIS study. Ann Neurol (2013) 1.54

Histopathologic correlates of radial stripes on MR images in lysosomal storage disorders. AJNR Am J Neuroradiol (2005) 1.53

Clinical proton MR spectroscopy in central nervous system disorders. Radiology (2014) 1.53

Frontal-striatal dysfunction during planning in obsessive-compulsive disorder. Arch Gen Psychiatry (2005) 1.53

Risk of rapid global functional decline in elderly patients with severe cerebral age-related white matter changes: the LADIS study. Arch Intern Med (2007) 1.52

Prediction of dementia in MCI patients based on core diagnostic markers for Alzheimer disease. Neurology (2013) 1.51

Clinical effect of neutralizing antibodies to interferon beta that persist long after cessation of therapy for multiple sclerosis. Arch Neurol (2010) 1.50

Disability outcome measures in multiple sclerosis clinical trials: current status and future prospects. Lancet Neurol (2012) 1.50

Determinants of cerebral atrophy rate at the time of diagnosis of multiple sclerosis. Arch Neurol (2007) 1.47

The clinical profile of right temporal lobe atrophy. Brain (2009) 1.46

Mutations in DARS cause hypomyelination with brain stem and spinal cord involvement and leg spasticity. Am J Hum Genet (2013) 1.46

The efficacy of natalizumab in patients with relapsing multiple sclerosis: subgroup analyses of AFFIRM and SENTINEL. J Neurol (2009) 1.46