Published in Drug Discov Today on May 15, 2005
Subambient pressure ionization with nanoelectrospray source and interface for improved sensitivity in mass spectrometry. Anal Chem (2008) 1.40
Optimized proteomic analysis of a mouse model of cerebellar dysfunction using amine-specific isobaric tags. Proteomics (2006) 1.37
A bayesian approach to protein inference problem in shotgun proteomics. J Comput Biol (2009) 1.26
STAT1-dependent expression of energy metabolic pathways links tumour growth and radioresistance to the Warburg effect. BMC Med (2009) 1.26
Applications of proteomics in the study of inflammatory bowel diseases: Current status and future directions with available technologies. Inflamm Bowel Dis (2009) 1.05
Verification of single-peptide protein identifications by the application of complementary database search algorithms. J Biomol Tech (2006) 0.91
Effects of column and gradient lengths on peak capacity and peptide identification in nanoflow LC-MS/MS of complex proteomic samples. J Am Soc Mass Spectrom (2012) 0.91
Characterizing the Escherichia coli O157:H7 proteome including protein associations with higher order assemblies. PLoS One (2011) 0.84
Improving liquid chromatography-mass spectrometry sensitivity using a subambient pressure ionization with nanoelectrospray (SPIN) interface. J Am Soc Mass Spectrom (2011) 0.84
Discrimination of grade 2 and 3 cervical intraepithelial neoplasia by means of analysis of water soluble proteins recovered from cervical biopsies. Proteome Sci (2011) 0.82
The EIPeptiDi tool: enhancing peptide discovery in ICAT-based LC MS/MS experiments. BMC Bioinformatics (2007) 0.80
Comprehensive analysis of proteins of pH fractionated samples using monolithic LC/MS/MS, intact MW measurement and MALDI-QIT-TOF MS. J Mass Spectrom (2007) 0.78
Prediction of spontaneous regression of cervical intraepithelial neoplasia lesions grades 2 and 3 by proteomic analysis. Int J Proteomics (2014) 0.77
A tool to evaluate correspondence between extraction ion chromatographic peaks and peptide-spectrum matches in shotgun proteomics experiments. Proteomics (2013) 0.75
Screening Method for the Discovery of Potential Bioactive Cysteine-Containing Peptides Using 3D Mass Mapping. J Am Soc Mass Spectrom (2015) 0.75
Histone H3 methylation by Set2 directs deacetylation of coding regions by Rpd3S to suppress spurious intragenic transcription. Cell (2005) 10.68
A proteomic view of the Plasmodium falciparum life cycle. Nature (2002) 10.65
Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein. Nature (2011) 7.92
Statistical analysis of membrane proteome expression changes in Saccharomyces cerevisiae. J Proteome Res (2006) 6.43
AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia. Mol Cell (2010) 4.99
Acetylation by Tip60 is required for selective histone variant exchange at DNA lesions. Science (2004) 4.97
Histone crosstalk between H2B monoubiquitination and H3 methylation mediated by COMPASS. Cell (2007) 4.49
Correlation of relative abundance ratios derived from peptide ion chromatograms and spectrum counting for quantitative proteomic analysis using stable isotope labeling. Anal Chem (2005) 4.16
Quantitative proteomic analysis of distinct mammalian Mediator complexes using normalized spectral abundance factors. Proc Natl Acad Sci U S A (2006) 3.71
Analyzing chromatin remodeling complexes using shotgun proteomics and normalized spectral abundance factors. Methods (2006) 3.37
A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology. Mol Cell (2004) 3.34
Lentiviral Vpx accessory factor targets VprBP/DCAF1 substrate adaptor for cullin 4 E3 ubiquitin ligase to enable macrophage infection. PLoS Pathog (2008) 3.27
Probabilistic assembly of human protein interaction networks from label-free quantitative proteomics. Proc Natl Acad Sci U S A (2008) 3.23
Proteasome recruitment and activation of the Uch37 deubiquitinating enzyme by Adrm1. Nat Cell Biol (2006) 3.14
Refinements to label free proteome quantitation: how to deal with peptides shared by multiple proteins. Anal Chem (2010) 3.07
Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler. Proc Natl Acad Sci U S A (2009) 3.02
Molecular regulation of histone H3 trimethylation by COMPASS and the regulation of gene expression. Mol Cell (2005) 2.89
Scm3 is essential to recruit the histone h3 variant cse4 to centromeres and to maintain a functional kinetochore. Mol Cell (2007) 2.82
Evolutionarily conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence. Mol Cell (2007) 2.74
Proteomic analysis by multidimensional protein identification technology. Methods Mol Biol (2006) 2.69
Lentiviral Vpr usurps Cul4-DDB1[VprBP] E3 ubiquitin ligase to modulate cell cycle. Proc Natl Acad Sci U S A (2007) 2.64
Human mediator subunit MED26 functions as a docking site for transcription elongation factors. Cell (2011) 2.53
Linking H3K79 trimethylation to Wnt signaling through a novel Dot1-containing complex (DotCom). Genes Dev (2010) 2.53
Chromatin remodelers Isw1 and Chd1 maintain chromatin structure during transcription by preventing histone exchange. Nat Struct Mol Biol (2012) 2.37
Proteomic survey of metabolic pathways in rice. Proc Natl Acad Sci U S A (2002) 2.27
Subunit composition and substrate specificity of a MOF-containing histone acetyltransferase distinct from the male-specific lethal (MSL) complex. J Biol Chem (2009) 2.23
SCF(Cyclin F) controls centrosome homeostasis and mitotic fidelity through CP110 degradation. Nature (2010) 2.15
A mammalian chromatin remodeling complex with similarities to the yeast INO80 complex. J Biol Chem (2005) 2.10
Statistical similarities between transcriptomics and quantitative shotgun proteomics data. Mol Cell Proteomics (2007) 2.05
Cyclin F-mediated degradation of ribonucleotide reductase M2 controls genome integrity and DNA repair. Cell (2012) 1.98
The deubiquitylation activity of Ubp8 is dependent upon Sgf11 and its association with the SAGA complex. Mol Cell Biol (2005) 1.95
The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes. J Biol Chem (2005) 1.93
ATAC is a double histone acetyltransferase complex that stimulates nucleosome sliding. Nat Struct Mol Biol (2008) 1.90
Parallel identification of new genes in Saccharomyces cerevisiae. Genome Res (2002) 1.89
Characterization of Cullin-box sequences that direct recruitment of Cul2-Rbx1 and Cul5-Rbx2 modules to Elongin BC-based ubiquitin ligases. J Biol Chem (2008) 1.82
DYRK1A protein kinase promotes quiescence and senescence through DREAM complex assembly. Genes Dev (2011) 1.82
Purification of a human SRCAP complex that remodels chromatin by incorporating the histone variant H2A.Z into nucleosomes. Biochemistry (2006) 1.81
YY1 functions with INO80 to activate transcription. Nat Struct Mol Biol (2007) 1.79
Delayed correlation of mRNA and protein expression in rapamycin-treated cells and a role for Ggc1 in cellular sensitivity to rapamycin. Mol Cell Proteomics (2009) 1.76
Distinct modes of regulation of the Uch37 deubiquitinating enzyme in the proteasome and in the Ino80 chromatin-remodeling complex. Mol Cell (2008) 1.71
Rtr1 is a CTD phosphatase that regulates RNA polymerase II during the transition from serine 5 to serine 2 phosphorylation. Mol Cell (2009) 1.68
Stable incorporation of sequence specific repressors Ash1 and Ume6 into the Rpd3L complex. Biochim Biophys Acta (2005) 1.66
Host cell factor and an uncharacterized SANT domain protein are stable components of ATAC, a novel dAda2A/dGcn5-containing histone acetyltransferase complex in Drosophila. Mol Cell Biol (2006) 1.60
The HIR corepressor complex binds to nucleosomes generating a distinct protein/DNA complex resistant to remodeling by SWI/SNF. Genes Dev (2005) 1.57
The COMPASS family of H3K4 methylases in Drosophila. Mol Cell Biol (2011) 1.54
Ctk complex-mediated regulation of histone methylation by COMPASS. Mol Cell Biol (2006) 1.50
The super elongation complex family of RNA polymerase II elongation factors: gene target specificity and transcriptional output. Mol Cell Biol (2012) 1.49
Quantitative shotgun proteomics using a protease with broad specificity and normalized spectral abundance factors. Mol Biosyst (2007) 1.44
Effect of dynamic exclusion duration on spectral count based quantitative proteomics. Anal Chem (2009) 1.44
The inhibition of polo kinase by matrimony maintains G2 arrest in the meiotic cell cycle. PLoS Biol (2007) 1.42
Proteomic analysis of Sox2-associated proteins during early stages of mouse embryonic stem cell differentiation identifies Sox21 as a novel regulator of stem cell fate. Stem Cells (2010) 1.40
Heterochromatin protein 1a stimulates histone H3 lysine 36 demethylation by the Drosophila KDM4A demethylase. Mol Cell (2008) 1.38
Retracted DNA-PKcs-PIDDosome: a nuclear caspase-2-activating complex with role in G2/M checkpoint maintenance. Cell (2009) 1.37
INTS3 controls the hSSB1-mediated DNA damage response. J Cell Biol (2009) 1.31
Ssu72 phosphatase-dependent erasure of phospho-Ser7 marks on the RNA polymerase II C-terminal domain is essential for viability and transcription termination. J Biol Chem (2012) 1.30
Combinatorial depletion analysis to assemble the network architecture of the SAGA and ADA chromatin remodeling complexes. Mol Syst Biol (2011) 1.29
FBH1 promotes DNA double-strand breakage and apoptosis in response to DNA replication stress. J Cell Biol (2013) 1.28
Structural changes in TAF4b-TFIID correlate with promoter selectivity. Mol Cell (2008) 1.27
Yeast Sgf73/Ataxin-7 serves to anchor the deubiquitination module into both SAGA and Slik(SALSA) HAT complexes. Epigenetics Chromatin (2009) 1.27
Subunit organization of the human INO80 chromatin remodeling complex: an evolutionarily conserved core complex catalyzes ATP-dependent nucleosome remodeling. J Biol Chem (2011) 1.27
Multidimensional separations-based shotgun proteomics. Chem Rev (2007) 1.23
Genomic and proteomic analysis of phiEco32, a novel Escherichia coli bacteriophage. J Mol Biol (2008) 1.21
CHD8 associates with human Staf and contributes to efficient U6 RNA polymerase III transcription. Mol Cell Biol (2007) 1.20
Highly reproducible label free quantitative proteomic analysis of RNA polymerase complexes. Mol Cell Proteomics (2010) 1.18
Regulation of H3K4 trimethylation via Cps40 (Spp1) of COMPASS is monoubiquitination independent: implication for a Phe/Tyr switch by the catalytic domain of Set1. Mol Cell Biol (2009) 1.18
An ortholog of the Ro autoantigen functions in 23S rRNA maturation in D. radiodurans. Genes Dev (2007) 1.17
Characterization of the yeast trimeric-SAS acetyltransferase complex. J Biol Chem (2005) 1.16
PARC and CUL7 form atypical cullin RING ligase complexes. Cancer Res (2007) 1.15
The ATAC acetyltransferase complex coordinates MAP kinases to regulate JNK target genes. Cell (2010) 1.15
Heterochromatin protein 1 (HP1) connects the FACT histone chaperone complex to the phosphorylated CTD of RNA polymerase II. Genes Dev (2010) 1.10
Polycomb repressive complex 2-dependent and -independent functions of Jarid2 in transcriptional regulation in Drosophila. Mol Cell Biol (2012) 1.10
Determination of protein interactome of transcription factor Sox2 in embryonic stem cells engineered for inducible expression of four reprogramming factors. J Biol Chem (2012) 1.10
Neuralized-like 1 (Neurl1) targeted to the plasma membrane by N-myristoylation regulates the Notch ligand Jagged1. J Biol Chem (2007) 1.09
Deacetylase inhibitors dissociate the histone-targeting ING2 subunit from the Sin3 complex. Chem Biol (2010) 1.09
Advances in shotgun proteomics and the analysis of membrane proteomes. J Proteomics (2010) 1.08
Post-transcription initiation function of the ubiquitous SAGA complex in tissue-specific gene activation. Genes Dev (2011) 1.08
The little elongation complex regulates small nuclear RNA transcription. Mol Cell (2011) 1.06
FBXL2- and PTPL1-mediated degradation of p110-free p85β regulatory subunit controls the PI(3)K signalling cascade. Nat Cell Biol (2013) 1.04
The tumour antigen PRAME is a subunit of a Cul2 ubiquitin ligase and associates with active NFY promoters. EMBO J (2011) 1.03
Examining the complexity of human RNA polymerase complexes using HaloTag technology coupled to label free quantitative proteomics. J Proteome Res (2012) 1.02
Mnd1/Hop2 facilitates Dmc1-dependent interhomolog crossover formation in meiosis of budding yeast. Mol Cell Biol (2006) 1.02
The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells. PLoS One (2013) 0.99
Evaluation of clustering algorithms for protein complex and protein interaction network assembly. J Proteome Res (2009) 0.97
A novel histone fold domain-containing protein that replaces TAF6 in Drosophila SAGA is required for SAGA-dependent gene expression. Genes Dev (2009) 0.97
A label free quantitative proteomic analysis of the Saccharomyces cerevisiae nucleus. J Proteomics (2008) 0.96
Determining protein complex connectivity using a probabilistic deletion network derived from quantitative proteomics. PLoS One (2009) 0.96
Shaggy/glycogen synthase kinase 3β and phosphorylation of Sarah/regulator of calcineurin are essential for completion of Drosophila female meiosis. Proc Natl Acad Sci U S A (2012) 0.95
Unraveling the ubiquitome of the human malaria parasite. J Biol Chem (2011) 0.95
Identification of FAM111A as an SV40 host range restriction and adenovirus helper factor. PLoS Pathog (2012) 0.95
A mammalian mediator subunit that shares properties with Saccharomyces cerevisiae mediator subunit Cse2. J Biol Chem (2003) 0.94
Identification and Characterization of a Schizosaccharomyces pombe RNA Polymerase II Elongation Factor with Similarity to the Metazoan Transcription Factor ELL. J Biol Chem (2006) 0.94
Human family with sequence similarity 60 member A (FAM60A) protein: a new subunit of the Sin3 deacetylase complex. Mol Cell Proteomics (2012) 0.93
The mammalian Mediator complex. FEBS Lett (2005) 0.92
Regulation of the CRL4(Cdt2) ubiquitin ligase and cell-cycle exit by the SCF(Fbxo11) ubiquitin ligase. Mol Cell (2013) 0.92
Building protein-protein interaction networks with proteomics and informatics tools. J Biol Chem (2011) 0.92
Nuclear cGMP-dependent kinase regulates gene expression via activity-dependent recruitment of a conserved histone deacetylase complex. PLoS Genet (2011) 0.91
The essential gene wda encodes a WD40 repeat subunit of Drosophila SAGA required for histone H3 acetylation. Mol Cell Biol (2006) 0.91
Loss of Drosophila Ataxin-7, a SAGA subunit, reduces H2B ubiquitination and leads to neural and retinal degeneration. Genes Dev (2014) 0.91
Quantitative proteomics demonstrates that the RNA polymerase II subunits Rpb4 and Rpb7 dissociate during transcriptional elongation. Mol Cell Proteomics (2013) 0.90
Improving proteomics mass accuracy by dynamic offline lock mass. Anal Chem (2011) 0.88