PubRank

Peter J van den Elsen

Author PubWeight™ 41.84‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 NLR family member NLRC5 is a transcriptional regulator of MHC class I genes. Proc Natl Acad Sci U S A 2010 1.90
2 Genetic variation in PCAF, a key mediator in epigenetics, is associated with reduced vascular morbidity and mortality: evidence for a new concept from three independent prospective studies. Heart 2010 1.46
3 HLA-E and HLA-G expression in classical HLA class I-negative tumors is of prognostic value for clinical outcome of early breast cancer patients. J Immunol 2010 1.38
4 NLRC5 cooperates with the RFX transcription factor complex to induce MHC class I gene expression. J Immunol 2012 1.29
5 Activated human T cells accomplish MHC class II expression through T cell-specific occupation of class II transactivator promoter III. J Immunol 2002 1.25
6 Mutations in ZBTB24 are associated with immunodeficiency, centromeric instability, and facial anomalies syndrome type 2. Am J Hum Genet 2011 1.24
7 Epigenetics in atherosclerosis and inflammation. J Cell Mol Med 2010 1.21
8 NLRC5: a key regulator of MHC class I-dependent immune responses. Nat Rev Immunol 2012 1.17
9 Epigenetic histone acetylation modifiers in vascular remodelling: new targets for therapy in cardiovascular disease. Eur Heart J 2009 1.14
10 Clusters of activated microglia in normal-appearing white matter show signs of innate immune activation. J Neuroinflammation 2012 1.09
11 Reduced human leukocyte antigen expression in advanced-stage Ewing sarcoma: implications for immune recognition. J Pathol 2009 1.09
12 Differential expression regulation of the alpha and beta subunits of the PA28 proteasome activator in mature dendritic cells. J Immunol 2005 1.09
13 E47, IRF-4, and PU.1 synergize to induce B-cell-specific activation of the class II transactivator promoter III (CIITA-PIII). Blood 2004 1.05
14 Heterogeneous clinical presentation in ICF syndrome: correlation with underlying gene defects. Eur J Hum Genet 2013 1.02
15 Unravelling the T-cell-mediated autoimmune attack on CNS myelin in a new primate EAE model induced with MOG34-56 peptide in incomplete adjuvant. Eur J Immunol 2011 0.98
16 CX3CL1 and CX3CR1 expression in human brain tissue: noninflammatory control versus multiple sclerosis. J Neuropathol Exp Neurol 2003 0.96
17 HLA-G transactivation by cAMP-response element-binding protein (CREB). An alternative transactivation pathway to the conserved major histocompatibility complex (MHC) class I regulatory routes. J Biol Chem 2002 0.94
18 Structural and functional differences between the promoters of independently expressed killer cell Ig-like receptors. Eur J Immunol 2005 0.94
19 CC chemokine receptor 5 gene promoter activation by the cyclic AMP response element binding transcription factor. Blood 2008 0.94
20 Preactive multiple sclerosis lesions offer novel clues for neuroprotective therapeutic strategies. CNS Neurol Disord Drug Targets 2011 0.93
21 Regulation of MHC class II expression in human T-cell malignancies. Blood 2003 0.92
22 Lack of IFN-gamma-mediated induction of the class II transactivator (CIITA) through promoter methylation is predominantly found in developmental tumor cell lines. Int J Cancer 2002 0.92
23 Epigenetic control of CCR5 transcript levels in immune cells and modulation by small molecules inhibitors. J Cell Mol Med 2012 0.92
24 Epigenetic silencing of MHC2TA transcription in cancer. Biochem Pharmacol 2006 0.91
25 Immunomodulation by statins: inhibition of cholesterol vs. isoprenoid biosynthesis. Biomed Pharmacother 2007 0.91
26 Oxidative phosphorylation induces de novo expression of the MHC class I in tumor cells through the ERK5 pathway. J Immunol 2010 0.89
27 Statins affect cell-surface expression of major histocompatibility complex class II molecules by disrupting cholesterol-containing microdomains. Hum Immunol 2005 0.87
28 Lack of MHC-II expression in activated mouse T cells correlates with DNA methylation at the CIITA-PIII region. Immunogenetics 2005 0.85
29 Uveal and cutaneous melanoma: shared expression characteristics of melanoma-associated antigens. Invest Ophthalmol Vis Sci 2005 0.84
30 Antigen-independent acquisition of MHC class II molecules by human T lymphocytes. Int Immunol 2004 0.83
31 Transcriptional regulation of the MHC class II trans-activator (CIITA) promoter III: identification of a novel regulatory region in the 5'-untranslated region and an important role for cAMP-responsive element binding protein 1 and activating transcription factor-1 in CIITA-promoter III transcriptional activation in B lymphocytes. J Immunol 2002 0.82
32 Genetic and epigenetic control of the major histocompatibility complex class Ib gene HLA-G in trophoblast cell lines. Ann N Y Acad Sci 2009 0.81
33 Hantaviral mechanisms driving HLA class I antigen presentation require both RIG-I and TRIF. Eur J Immunol 2013 0.81
34 Prenatal exposure to apoE deficiency and postnatal hypercholesterolemia are associated with altered cell-specific lysine methyltransferase and histone methylation patterns in the vasculature. Am J Pathol 2009 0.81
35 The single antigen expressing lines (SALs) concept: an excellent tool for screening for HLA-specific antibodies. Hum Immunol 2005 0.79
36 Epigenetic regulation of CIITA expression in human T-cells. Biochem Pharmacol 2011 0.79
37 Class II transactivator (CIITA) deficiency in tumor cells: complicated mechanisms or not? Am J Pathol 2003 0.78
38 Statins and control of MHC2TA gene transcription. Nat Med 2005 0.78
39 Transcriptional silencing of RFXAP in MHC class II-deficiency. Mol Immunol 2008 0.77
40 Simvastatin affects cell motility and actin cytoskeleton distribution of microglia. Glia 2006 0.77
41 Chromatin status of apoptosis genes correlates with sensitivity to chemo-, immune- and radiation therapy in colorectal cancer cell lines. Apoptosis 2014 0.77
42 Constitutive and IFNgamma-induced activation of MHC2TA promoter type III in human melanoma cell lines is governed by separate regulatory elements within the PIII upstream regulatory region. Mol Immunol 2006 0.76
43 Pre-term birth and severe pre-eclampsia are not associated with altered expression of HLA on human trophoblasts. Am J Reprod Immunol 2003 0.75
44 Bringing antigens to attention: a conspiracy of genes, proteins and cells. Curr Opin Immunol 2010 0.75