Published in Nature on June 26, 2005
FERONIA receptor-like kinase regulates RHO GTPase signaling of root hair development. Proc Natl Acad Sci U S A (2010) 1.82
Cell polarity signaling in Arabidopsis. Annu Rev Cell Dev Biol (2008) 1.81
Cis-element- and transcriptome-based screening of root hair-specific genes and their functional characterization in Arabidopsis. Plant Physiol (2009) 1.80
ROP/RAC GTPase signaling. Curr Opin Plant Biol (2007) 1.57
A distinct mechanism regulating a pollen-specific guanine nucleotide exchange factor for the small GTPase Rop in Arabidopsis thaliana. Proc Natl Acad Sci U S A (2007) 1.56
Members of a novel class of Arabidopsis Rho guanine nucleotide exchange factors control Rho GTPase-dependent polar growth. Plant Cell (2006) 1.49
Rho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and disease. Oncogene (2013) 1.44
Regulation of membrane trafficking, cytoskeleton dynamics, and cell polarity by ROP/RAC GTPases. Plant Physiol (2008) 1.37
Tobacco RhoGTPase ACTIVATING PROTEIN1 spatially restricts signaling of RAC/Rop to the apex of pollen tubes. Plant Cell (2006) 1.37
Tip growth: signaling in the apical dome. Curr Opin Plant Biol (2008) 1.26
Glycosylphosphatidylinositol-anchored proteins as chaperones and co-receptors for FERONIA receptor kinase signaling in Arabidopsis. Elife (2015) 1.14
New insights into Rho signaling from plant ROP/Rac GTPases. Trends Cell Biol (2012) 1.11
Coexpression-based clustering of Arabidopsis root genes predicts functional modules in early phosphate deficiency signaling. Plant Physiol (2011) 1.11
A SPIKE1 signaling complex controls actin-dependent cell morphogenesis through the heteromeric WAVE and ARP2/3 complexes. Proc Natl Acad Sci U S A (2008) 1.11
The pollen receptor kinase LePRK2 mediates growth-promoting signals and positively regulates pollen germination and tube growth. Plant Physiol (2008) 1.06
Differential effects of prenylation and s-acylation on type I and II ROPS membrane interaction and function. Plant Physiol (2010) 1.02
RAC/ROP GTPases and auxin signaling. Plant Cell (2011) 1.00
AtPRK2 promotes ROP1 activation via RopGEFs in the control of polarized pollen tube growth. Mol Plant (2012) 1.00
Ectopic expression of constitutively activated RACB in barley enhances susceptibility to powdery mildew and abiotic stress. Plant Physiol (2005) 0.98
Are small GTPases signal hubs in sugar-mediated induction of fructan biosynthesis? PLoS One (2009) 0.95
The dynamic interplay of plasma membrane domains and cortical microtubules in secondary cell wall patterning. Front Plant Sci (2013) 0.93
RHO GTPase in plants: Conservation and invention of regulators and effectors. Small GTPases (2010) 0.93
Invasive cells in animals and plants: searching for LECA machineries in later eukaryotic life. Biol Direct (2013) 0.92
F-actin organization and pollen tube tip growth in Arabidopsis are dependent on the gametophyte-specific Armadillo repeat protein ARO1. Plant Cell (2008) 0.90
Rho family GTPase-dependent immunity in plants and animals. Front Plant Sci (2014) 0.90
A G-protein activation cascade from Arl13B to Arl3 and implications for ciliary targeting of lipidated proteins. Elife (2015) 0.88
STIL, a peculiar molecule from styles, specifically dephosphorylates the pollen receptor kinase LePRK2 and stimulates pollen tube growth in vitro. BMC Plant Biol (2010) 0.87
Tip-localized receptors control pollen tube growth and LURE sensing in Arabidopsis. Nature (2016) 0.86
RopGEF7 regulates PLETHORA-dependent maintenance of the root stem cell niche in Arabidopsis. Plant Cell (2011) 0.85
Receptor-like kinases as surface regulators for RAC/ROP-mediated pollen tube growth and interaction with the pistil. AoB Plants (2011) 0.83
Brassica napus Rop GTPases and their expression in microspore cultures. Planta (2006) 0.83
FERONIA as an upstream receptor kinase for polar cell growth in plants. Proc Natl Acad Sci U S A (2010) 0.83
The Arabidopsis Rho of plants GTPase AtROP6 functions in developmental and pathogen response pathways. Plant Physiol (2013) 0.82
Overexpression of the tomato pollen receptor kinase LePRK1 rewires pollen tube growth to a blebbing mode. Plant Cell (2014) 0.82
The juxtamembrane and carboxy-terminal domains of Arabidopsis PRK2 are critical for ROP-induced growth in pollen tubes. J Exp Bot (2013) 0.80
ROP3 GTPase contributes to polar auxin transport and auxin responses and is important for embryogenesis and seedling growth in Arabidopsis. Plant Cell (2014) 0.80
Ethylene negatively regulates transcript abundance of ROP-GAP rheostat-encoding genes and affects apoplastic reactive oxygen species homeostasis in epicarps of cold stored apple fruits. J Exp Bot (2015) 0.80
The Arabidopsis small GTPase AtRAC7/ROP9 is a modulator of auxin and abscisic acid signalling. J Exp Bot (2013) 0.79
Regulation of pollen tube polarity: Feedback loops rule. Plant Signal Behav (2008) 0.79
Purification and crystallization of the catalytic PRONE domain of RopGEF8 and its complex with Rop4 from Arabidopsis thaliana. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.78
FERONIA and Her Pals: Functions and Mechanisms. Plant Physiol (2016) 0.78
The Interaction of CCDC104/BARTL1 with Arl3 and Implications for Ciliary Function. Structure (2015) 0.78
Arabidopsis RhoGDIs Are Critical for Cellular Homeostasis of Pollen Tubes. Plant Physiol (2015) 0.77
Release of GTP Exchange Factor Mediated Down-Regulation of Abscisic Acid Signal Transduction through ABA-Induced Rapid Degradation of RopGEFs. PLoS Biol (2016) 0.76
Novel ABP1-TMK auxin sensing system controls ROP GTPase-mediated interdigitated cell expansion in Arabidopsis. Small GTPases (2014) 0.76
SPIKE1 Activates ROP GTPase to Modulate Petal Growth and Shape. Plant Physiol (2016) 0.76
A pull-down procedure for the identification of unknown GEFs for small GTPases. Small GTPases (2016) 0.76
CPK3-phosphorylated RhoGDI1 is essential in the development of Arabidopsis seedlings and leaf epidermal cells. J Exp Bot (2013) 0.75
Conserved Roles of CrRLK1L Receptor-Like Kinases in Cell Expansion and Reproduction from Algae to Angiosperms. Front Plant Sci (2016) 0.75
Function of Arabidopsis SWAP70 GEF in immune response. Plant Signal Behav (2012) 0.75
New insights into the dimerization of small GTPase Rac/ROP guanine nucleotide exchange factors in rice. Plant Signal Behav (2015) 0.75
Identification of the arabidopsis RAM/MOR signalling network: adding new regulatory players in plant stem cell maintenance and cell polarization. Ann Bot (2015) 0.75
Purification, crystallization and preliminary X-ray diffraction analysis of the plant Rho protein ROP5. Acta Crystallogr Sect F Struct Biol Cryst Commun (2007) 0.75
Auxin Signaling in Regulation of Plant Translation Reinitiation. Front Plant Sci (2017) 0.75
GEFs and GAPs: critical elements in the control of small G proteins. Cell (2007) 7.32
An acylation cycle regulates localization and activity of palmitoylated Ras isoforms. Science (2005) 5.99
Small molecule inhibition of the KRAS-PDEδ interaction impairs oncogenic KRAS signalling. Nature (2013) 5.04
Structural basis of Wnt recognition by Frizzled. Science (2012) 4.31
Structural insight into filament formation by mammalian septins. Nature (2007) 2.90
It takes two to tango: regulation of G proteins by dimerization. Nat Rev Mol Cell Biol (2009) 2.34
The complex of Arl2-GTP and PDE delta: from structure to function. EMBO J (2002) 2.24
Structure and regulation of the cAMP-binding domains of Epac2. Nat Struct Biol (2003) 2.11
The regulation of mDia1 by autoinhibition and its release by Rho*GTP. EMBO J (2005) 2.10
Capturing cyclic nucleotides in action: snapshots from crystallographic studies. Nat Rev Mol Cell Biol (2007) 2.07
The GTPase-activating protein Rap1GAP uses a catalytic asparagine. Nature (2004) 2.06
Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo. Nat Chem Biol (2011) 2.00
How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP. Nature (2006) 1.92
Structure of the cyclic-AMP-responsive exchange factor Epac2 in its auto-inhibited state. Nature (2006) 1.88
The GDI-like solubilizing factor PDEδ sustains the spatial organization and signalling of Ras family proteins. Nat Cell Biol (2011) 1.87
Dimerisation-dependent GTPase reaction of MnmE: how potassium acts as GTPase-activating element. EMBO J (2006) 1.75
The core FH2 domain of diaphanous-related formins is an elongated actin binding protein that inhibits polymerization. Mol Cell (2004) 1.74
A restricted spectrum of NRAS mutations causes Noonan syndrome. Nat Genet (2009) 1.71
Structure of a 14-3-3 coordinated hexamer of the plant plasma membrane H+ -ATPase by combining X-ray crystallography and electron cryomicroscopy. Mol Cell (2007) 1.67
Structural view of a fungal toxin acting on a 14-3-3 regulatory complex. EMBO J (2003) 1.67
The retinitis pigmentosa 2 gene product is a GTPase-activating protein for Arf-like 3. Nat Struct Mol Biol (2008) 1.64
Structural basis for the reversible activation of a Rho protein by the bacterial toxin SopE. EMBO J (2002) 1.64
Structural snapshots of full-length Jak1, a transmembrane gp130/IL-6/IL-6Rα cytokine receptor complex, and the receptor-Jak1 holocomplex. Structure (2011) 1.63
Structure of the Roc-COR domain tandem of C. tepidum, a prokaryotic homologue of the human LRRK2 Parkinson kinase. EMBO J (2008) 1.62
The VASP tetramerization domain is a right-handed coiled coil based on a 15-residue repeat. Proc Natl Acad Sci U S A (2004) 1.57
Ligand-mediated activation of the cAMP-responsive guanine nucleotide exchange factor Epac. J Biol Chem (2003) 1.53
RanGAP mediates GTP hydrolysis without an arginine finger. Nature (2002) 1.50
Structural insights into HypB, a GTP-binding protein that regulates metal binding. J Biol Chem (2006) 1.47
Prevalence and clinical characteristics of symptomatic patients with obstructive coronary artery disease in the absence of coronary calcifications. Acad Radiol (2010) 1.39
Structural and dynamic determinants of type I interferon receptor assembly and their functional interpretation. Immunol Rev (2012) 1.38
Phosphorylation-independent interaction between 14-3-3 and exoenzyme S: from structure to pathogenesis. EMBO J (2007) 1.38
GTP-induced conformational changes in septins and implications for function. Proc Natl Acad Sci U S A (2009) 1.35
Regulation of dynamic polarity switching in bacteria by a Ras-like G-protein and its cognate GAP. EMBO J (2010) 1.35
Nucleotide binding and filament assembly of recombinant yeast septin complexes. Biol Chem (2005) 1.34
The structure of the TrmE GTP-binding protein and its implications for tRNA modification. EMBO J (2004) 1.34
The GAP arginine finger movement into the catalytic site of Ras increases the activation entropy. Proc Natl Acad Sci U S A (2008) 1.30
Rap-specific GTPase activating protein follows an alternative mechanism. J Biol Chem (2002) 1.28
The Rap-RapGAP complex: GTP hydrolysis without catalytic glutamine and arginine residues. EMBO J (2008) 1.28
Human OLA1 defines an ATPase subfamily in the Obg family of GTP-binding proteins. J Biol Chem (2007) 1.28
Specificity of interactions between mDia isoforms and Rho proteins. J Biol Chem (2008) 1.27
Stabilizing a weak binding state for effectors in the human ras protein by cyclen complexes. Angew Chem Int Ed Engl (2010) 1.25
Germline KRAS mutations cause aberrant biochemical and physical properties leading to developmental disorders. Hum Mutat (2010) 1.24
GAP1 family members constitute bifunctional Ras and Rap GTPase-activating proteins. J Biol Chem (2006) 1.22
Structural evidence for a common intermediate in small G protein-GEF reactions. Mol Cell (2007) 1.20
Communication between the regulatory and the catalytic region of the cAMP-responsive guanine nucleotide exchange factor Epac. J Biol Chem (2003) 1.18
Specificity of Arl2/Arl3 signaling is mediated by a ternary Arl3-effector-GAP complex. FEBS Lett (2008) 1.17
Structural analysis of the Ras-like G protein MglA and its cognate GAP MglB and implications for bacterial polarity. EMBO J (2011) 1.16
Crystal structure of the human retinitis pigmentosa 2 protein and its interaction with Arl3. Structure (2006) 1.15
Characterization of the GbpD-activated Rap1 pathway regulating adhesion and cell polarity in Dictyostelium discoideum. J Biol Chem (2006) 1.14
Reassessment of the role of FKBP38 in the Rheb/mTORC1 pathway. FEBS Lett (2009) 1.13
Structural basis for Arl3-specific release of myristoylated ciliary cargo from UNC119. EMBO J (2012) 1.12
SOS1 is the second most common Noonan gene but plays no major role in cardio-facio-cutaneous syndrome. J Med Genet (2007) 1.08
Perturbation of the conformational equilibria in Ras by selective mutations as studied by 31P NMR spectroscopy. FEBS Lett (2004) 1.08
Synthesis of the Rheb and K-Ras4B GTPases. Angew Chem Int Ed Engl (2010) 1.07
A phosphoryl transfer intermediate in the GTPase reaction of Ras in complex with its GTPase-activating protein. Proc Natl Acad Sci U S A (2006) 1.06
Fluorescence methods in the study of small GTP-binding proteins. Methods Mol Biol (2002) 1.05
Characterisation of PDZ-GEFs, a family of guanine nucleotide exchange factors specific for Rap1 and Rap2. Biochim Biophys Acta (2003) 1.02
The structure of an Arf-ArfGAP complex reveals a Ca2+ regulatory mechanism. Cell (2010) 1.02
Fourier transform infrared spectroscopy on the Rap.RapGAP reaction, GTPase activation without an arginine finger. J Biol Chem (2004) 1.02
Biochemical characterization of the Ran-RanBP1-RanGAP system: are RanBP proteins and the acidic tail of RanGAP required for the Ran-RanGAP GTPase reaction? Mol Cell Biol (2003) 1.02
Kissing G domains of MnmE monitored by X-ray crystallography and pulse electron paramagnetic resonance spectroscopy. PLoS Biol (2009) 1.01
Assessment of an advanced image-based technique to calculate virtual monoenergetic computed tomographic images from a dual-energy examination to improve contrast-to-noise ratio in examinations using iodinated contrast media. Invest Radiol (2014) 1.01
Performing MR-guided biopsies in clinical routine: factors that influence accuracy and procedure time. Eur Radiol (2011) 0.99
Roco kinase structures give insights into the mechanism of Parkinson disease-related leucine-rich-repeat kinase 2 mutations. Proc Natl Acad Sci U S A (2012) 0.99
Lipidated ras and rab peptides and proteins--synthesis, structure, and function. Angew Chem Int Ed Engl (2006) 0.99
The interplay between RPGR, PDEδ and Arl2/3 regulate the ciliary targeting of farnesylated cargo. EMBO Rep (2013) 0.98
Coronary CT angiography with dual source computed tomography in 170 patients. Eur J Radiol (2009) 0.98
Rho proteins of plants--functional cycle and regulation of cytoskeletal dynamics. Eur J Cell Biol (2011) 0.98
G-domain dimerization orchestrates the tRNA wobble modification reaction in the MnmE/GidA complex. J Mol Biol (2009) 0.97
A Rap/phosphatidylinositol 3-kinase pathway controls pseudopod formation [corrected]. Mol Biol Cell (2010) 0.96
Unravelling the mechanism of dual-specificity GAPs. EMBO J (2010) 0.96
Clinical evaluation and potential radiation dose reduction of the novel sinogram-affirmed iterative reconstruction technique (SAFIRE) in abdominal computed tomography angiography. Acad Radiol (2012) 0.96
Structure and function of Rho-type molecular switches in plants. Plant Physiol Biochem (2007) 0.95
Properties of the interaction of Arf-like protein 2 with PDEdelta. J Mol Biol (2005) 0.94
Diagnostic and interventional MRI of the sacroiliac joints using a 1.5-T open-bore magnet: a one-stop-shopping approach. AJR Am J Roentgenol (2008) 0.93
Conformational states of Ras complexed with the GTP analogue GppNHp or GppCH2p: implications for the interaction with effector proteins. Biochemistry (2005) 0.93
Structural and biochemical properties of Sept7, a unique septin required for filament formation. Biol Chem (2011) 0.92
RPGR and RP2: targets for the treatment of X-linked retinitis pigmentosa? Expert Opin Ther Targets (2009) 0.91
Amino acids of the bacterial toxin SopE involved in G nucleotide exchange on Cdc42. J Biol Chem (2003) 0.91
Cardiac dual-source computed tomography: effect of body mass index on image quality and diagnostic accuracy. Invest Radiol (2008) 0.91
Freehand real-time MRI-guided lumbar spinal injection procedures at 1.5 T: feasibility, accuracy, and safety. AJR Am J Roentgenol (2009) 0.90
Dual-source computed tomography: estimation of radiation exposure of ECG-gated and ECG-triggered coronary angiography. Eur J Radiol (2008) 0.90
The accuracy of 1- and 3-mm slices in coronary calcium scoring using multi-slice CT in vitro and in vivo. Eur Radiol (2006) 0.90
Estimation of radiation exposure of 128-slice 4D-perfusion CT for the assessment of tumor vascularity. Korean J Radiol (2010) 0.90
Insight into catalysis of a unique GTPase reaction by a combined biochemical and FTIR approach. J Mol Biol (2006) 0.89
Automated computed tomography dose-saving algorithm to protect radiosensitive tissues: estimation of radiation exposure and image quality considerations. Invest Radiol (2012) 0.89
Fluoride complexes of oncogenic Ras mutants to study the Ras-RasGap interaction. Biol Chem (2008) 0.89
Estimation of the radiation exposure of a chest pain protocol with ECG-gating in dual-source computed tomography. Eur Radiol (2008) 0.89
Quantitative parameters to compare image quality of non-invasive coronary angiography with 16-slice, 64-slice and dual-source computed tomography. Eur Radiol (2008) 0.88
Single-source dual-energy computed tomography: use of monoenergetic extrapolation for a reduction of metal artifacts. Invest Radiol (2014) 0.88
Magnetic resonance imaging-guided osseous biopsy in children with chronic recurrent multifocal osteomyelitis. Cardiovasc Intervent Radiol (2011) 0.87
A structural rationale for selective stabilization of anti-tumor interactions of 14-3-3 proteins by cotylenin A. J Mol Biol (2009) 0.87
The crystal structure of the Ran-Nup153ZnF2 complex: a general Ran docking site at the nuclear pore complex. Structure (2008) 0.87
Evaluation of automated attenuation-based tube current adaptation for coronary calcium scoring in MDCT in a cohort of 262 patients. Eur Radiol (2007) 0.86
Virtual nonenhanced dual-energy CT urography with tin-filter technology: determinants of detection of urinary calculi in the renal collecting system. Radiology (2012) 0.86
Human septin isoforms and the GDP-GTP cycle. Biol Chem (2014) 0.85
Ras GTPase activating (RasGAP) activity of the dual specificity GAP protein Rasal requires colocalization and C2 domain binding to lipid membranes. Proc Natl Acad Sci U S A (2012) 0.85
Predicted incorporation of non-native substrates by a polyketide synthase yields bioactive natural product derivatives. Chembiochem (2014) 0.85
Stabilization of G domain conformations in the tRNA-modifying MnmE-GidA complex observed with double electron electron resonance spectroscopy. J Biol Chem (2010) 0.85