Protein identification using sequential ion/ion reactions and tandem mass spectrometry.

PubWeight™: 3.77‹?› | Rank: Top 1%

🔗 View Article (PMC 1172258)

Published in Proc Natl Acad Sci U S A on June 27, 2005

Authors

Joshua J Coon1, Beatrix Ueberheide, John E P Syka, Deanna D Dryhurst, Juan Ausio, Jeffrey Shabanowitz, Donald F Hunt

Author Affiliations

1: Department of Chemistry, and Engineering Physics Program, University of Virginia, Charlottesville, VA 22901, USA.

Articles citing this

(truncated to the top 100)

Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry. Proc Natl Acad Sci U S A (2007) 5.09

Decision tree-driven tandem mass spectrometry for shotgun proteomics. Nat Methods (2008) 3.53

Supplemental activation method for high-efficiency electron-transfer dissociation of doubly protonated peptide precursors. Anal Chem (2007) 3.32

Cathepsin L proteolytically processes histone H3 during mouse embryonic stem cell differentiation. Cell (2008) 3.09

The utility of ETD mass spectrometry in proteomic analysis. Biochim Biophys Acta (2006) 2.85

Decoding protein modifications using top-down mass spectrometry. Nat Methods (2007) 2.62

High throughput characterization of combinatorial histone codes. Mol Cell Proteomics (2009) 2.52

Long-distance combinatorial linkage between methylation and acetylation on histone H3 N termini. Proc Natl Acad Sci U S A (2007) 2.43

Mass spectrometry for proteomics. Curr Opin Chem Biol (2008) 2.31

Mass spectrometry identifies and quantifies 74 unique histone H4 isoforms in differentiating human embryonic stem cells. Proc Natl Acad Sci U S A (2008) 2.29

A proteomics grade electron transfer dissociation-enabled hybrid linear ion trap-orbitrap mass spectrometer. J Proteome Res (2008) 1.92

Implementation of electron-transfer dissociation on a hybrid linear ion trap-orbitrap mass spectrometer. Anal Chem (2007) 1.92

Methods for analyzing peptides and proteins on a chromatographic timescale by electron-transfer dissociation mass spectrometry. Nat Protoc (2008) 1.87

Post-acquisition ETD spectral processing for increased peptide identifications. J Am Soc Mass Spectrom (2009) 1.86

Implementation of ion/ion reactions in a quadrupole/time-of-flight tandem mass spectrometer. Anal Chem (2006) 1.72

Mass spectrometry and the emerging field of glycomics. Chem Biol (2008) 1.69

Collisions or electrons? Protein sequence analysis in the 21st century. Anal Chem (2009) 1.62

Top-down proteomics on a chromatographic time scale using linear ion trap fourier transform hybrid mass spectrometers. Anal Chem (2007) 1.60

Comprehensive comparison of collision induced dissociation and electron transfer dissociation. Anal Chem (2008) 1.58

Analysis of intact proteins on a chromatographic time scale by electron transfer dissociation tandem mass spectrometry. Int J Mass Spectrom (2007) 1.56

Improving software performance for peptide electron transfer dissociation data analysis by implementation of charge state- and sequence-dependent scoring. Mol Cell Proteomics (2010) 1.50

On-line LC-MS approach combining collision-induced dissociation (CID), electron-transfer dissociation (ETD), and CID of an isolated charge-reduced species for the trace-level characterization of proteins with post-translational modifications. J Proteome Res (2007) 1.44

Breaking the histone code with quantitative mass spectrometry. Expert Rev Proteomics (2011) 1.39

Accurate mass measurements in proteomics. Chem Rev (2007) 1.36

CDK9 regulates AR promoter selectivity and cell growth through serine 81 phosphorylation. Mol Endocrinol (2010) 1.35

New and automated MSn approaches for top-down identification of modified proteins. J Am Soc Mass Spectrom (2005) 1.33

Covalent modification of gaseous peptide ions with N-hydroxysuccinimide ester reagent ions. J Am Chem Soc (2010) 1.32

Top-down identification and characterization of biomolecules by mass spectrometry. J Am Soc Mass Spectrom (2008) 1.31

Mitochondrial phosphoproteome revealed by an improved IMAC method and MS/MS/MS. Mol Cell Proteomics (2007) 1.27

Assessing the dynamic range and peak capacity of nanoflow LC-FAIMS-MS on an ion trap mass spectrometer for proteomics. Anal Chem (2008) 1.24

Phosphopeptide anion characterization via sequential charge inversion and electron-transfer dissociation. Anal Chem (2006) 1.23

Phage infection of an environmentally relevant marine bacterium alters host metabolism and lysate composition. ISME J (2013) 1.23

Rapid sensitive analysis of cysteine rich peptide venom components. Proc Natl Acad Sci U S A (2009) 1.21

An integrated top-down and bottom-up strategy for broadly characterizing protein isoforms and modifications. J Proteome Res (2009) 1.21

Capillary electrophoresis-mass spectrometry as a powerful tool in biomarker discovery and clinical diagnosis: an update of recent developments. Mass Spectrom Rev (2009) 1.19

Histone variants: emerging players in cancer biology. Cell Mol Life Sci (2013) 1.17

Characterization of the histone H2A.Z-1 and H2A.Z-2 isoforms in vertebrates. BMC Biol (2009) 1.17

High-resolution proteome/peptidome analysis of peptides and low-molecular-weight proteins in urine. Proteomics Clin Appl (2007) 1.17

Analysis of proteins and peptides on a chromatographic timescale by electron-transfer dissociation MS. FEBS J (2007) 1.14

The evolutionary differentiation of two histone H2A.Z variants in chordates (H2A.Z-1 and H2A.Z-2) is mediated by a stepwise mutation process that affects three amino acid residues. BMC Evol Biol (2009) 1.12

Analysis of histones in Xenopus laevis. II. mass spectrometry reveals an index of cell type-specific modifications on H3 and H4. J Biol Chem (2008) 1.12

Sensitive and specific identification of wild type and variant proteins from 8 to 669 kDa using top-down mass spectrometry. Mol Cell Proteomics (2008) 1.09

Intra- and inter-molecular cross-linking of peptide ions in the gas phase: reagents and conditions. J Am Soc Mass Spectrom (2011) 1.07

Laserspray ionization, a new atmospheric pressure MALDI method for producing highly charged gas-phase ions of peptides and proteins directly from solid solutions. Mol Cell Proteomics (2009) 1.06

Characterization and diagnostic value of amino acid side chain neutral losses following electron-transfer dissociation. J Am Soc Mass Spectrom (2011) 1.05

Accurate localization and relative quantification of arginine methylation using nanoflow liquid chromatography coupled to electron transfer dissociation and orbitrap mass spectrometry. J Am Soc Mass Spectrom (2008) 1.03

A combination of H2A.Z and H4 acetylation recruits Brd2 to chromatin during transcriptional activation. PLoS Genet (2012) 1.02

Modification of Pseudomonas aeruginosa Pa5196 type IV Pilins at multiple sites with D-Araf by a novel GT-C family Arabinosyltransferase, TfpW. J Bacteriol (2008) 1.02

Dual electrospray ion source for electron-transfer dissociation on a hybrid linear ion trap-orbitrap mass spectrometer. Anal Chem (2007) 1.01

Taking aim at shotgun phosphoproteomics. Anal Biochem (2007) 0.99

A combinatorial H4 tail library for exploring the histone code. Biochemistry (2008) 0.99

Gas-phase chemistry of multiply charged bioions in analytical mass spectrometry. Annu Rev Anal Chem (Palo Alto Calif) (2010) 0.99

Hydrophilic interaction liquid chromatography (HILIC) in proteomics. Anal Bioanal Chem (2008) 0.99

Mass spectrometry-based strategies for characterization of histones and their post-translational modifications. Expert Rev Proteomics (2007) 0.98

Glycosylation and disulfide bond analysis of transiently and stably expressed clade C HIV-1 gp140 trimers in 293T cells identifies disulfide heterogeneity present in both proteins and differences in O-linked glycosylation. J Proteome Res (2014) 0.97

Optimization of electron transfer dissociation via informed selection of reagents and operating parameters. Anal Chem (2012) 0.97

Electron transfer dissociation mass spectrometry in proteomics. Proteomics (2012) 0.97

Stable high volumetric production of glycosylated human recombinant IFNalpha2b in HEK293 cells. BMC Biotechnol (2008) 0.97

Nano-LC FTICR tandem mass spectrometry for top-down proteomics: routine baseline unit mass resolution of whole cell lysate proteins up to 72 kDa. Anal Chem (2012) 0.97

Sources of Urinary Proteins and their Analysis by Urinary Proteomics for the Detection of Biomarkers of Disease. Proteomics Clin Appl (2009) 0.97

Ion/ion reactions: new chemistry for analytical MS. Anal Chem (2009) 0.96

Evolution of instrumentation for the study of gas-phase ion/ion chemistry via mass spectrometry. J Am Soc Mass Spectrom (2007) 0.96

Xlink-identifier: an automated data analysis platform for confident identifications of chemically cross-linked peptides using tandem mass spectrometry. J Proteome Res (2011) 0.96

Toward defining the phosphoproteome of Xenopus laevis embryos. Dev Dyn (2009) 0.94

Protein derivatization and sequential ion/ion reactions to enhance sequence coverage produced by electron transfer dissociation mass spectrometry. Int J Mass Spectrom (2015) 0.94

De novo protein sequence analysis of Macaca mulatta. BMC Genomics (2007) 0.93

Gas-phase rearrangements do not affect site localization reliability in phosphoproteomics data sets. J Proteome Res (2010) 0.93

Spatially-directed protein identification from tissue sections by top-down LC-MS/MS with electron transfer dissociation. Anal Chem (2013) 0.93

Top-down protein identification/characterization of a priori unknown proteins via ion trap collision-induced dissociation and ion/ion reactions in a quadrupole/time-of-flight tandem mass spectrometer. Anal Chem (2009) 0.92

A semisynthetic strategy to generate phosphorylated and acetylated histone H2B. Chembiochem (2009) 0.91

Peptide identification by tandem mass spectrometry with alternate fragmentation modes. Mol Cell Proteomics (2012) 0.91

Fragmentation of multiply-charged intact protein ions using MALDI TOF-TOF mass spectrometry. J Am Soc Mass Spectrom (2007) 0.91

Coupling capillary zone electrophoresis with electron transfer dissociation and activated ion electron transfer dissociation for top-down proteomics. Anal Chem (2015) 0.91

Electron transfer dissociation of doubly sodiated glycerophosphocholine lipids. J Am Soc Mass Spectrom (2007) 0.89

Electron transfer dissociation (ETD): the mass spectrometric breakthrough essential for O-GlcNAc protein site assignments-a study of the O-GlcNAcylated protein host cell factor C1. Proteomics (2013) 0.88

Ultratrace liquid chromatography/mass spectrometry analysis of large peptides with post-translational modifications using narrow-bore poly(styrene-divinylbenzene) monolithic columns and extended range proteomic analysis. J Chromatogr A (2007) 0.88

Identification and characterization of the two isoforms of the vertebrate H2A.Z histone variant. Nucleic Acids Res (2010) 0.87

Valence anions of N-acetylproline in the gas phase: computational and anion photoelectron spectroscopic studies. J Chem Phys (2011) 0.87

Unraveling the histone's potential: a proteomics perspective. Epigenetics (2008) 0.86

Analytical technologies for identification and characterization of the plant N-glycoproteome. Front Plant Sci (2012) 0.86

Mass spectrometry based proteomics in urine biomarker discovery. World J Urol (2007) 0.86

Extensive and varied modifications in histone H2B of wild-type and histone deacetylase 1 mutant Neurospora crassa. Biochemistry (2010) 0.85

Chemical and biochemical approaches in the study of histone methylation and demethylation. Med Res Rev (2012) 0.85

Structural identification of electron transfer dissociation products in mass spectrometry using infrared ion spectroscopy. Nat Commun (2016) 0.85

Exploring salt bridge structures of gas-phase protein ions using multiple stages of electron transfer and collision induced dissociation. J Am Soc Mass Spectrom (2014) 0.85

Integrated workflow for characterizing intact phosphoproteins from complex mixtures. Anal Chem (2009) 0.84

Chemical derivatization of peptide carboxyl groups for highly efficient electron transfer dissociation. J Am Soc Mass Spectrom (2013) 0.84

Modern approaches for investigating epigenetic signaling pathways. J Appl Physiol (1985) (2010) 0.84

Histone H2A.Z deregulation in prostate cancer. Cause or effect? Cancer Metastasis Rev (2014) 0.84

Recent advances in the MS analysis of glycoproteins: Theoretical considerations. Electrophoresis (2010) 0.84

A Calibration Routine for Efficient ETD in Large-Scale Proteomics. J Am Soc Mass Spectrom (2015) 0.84

Enhanced Dissociation of Intact Proteins with High Capacity Electron Transfer Dissociation. J Am Soc Mass Spectrom (2015) 0.83

Cigarette smoke induces distinct histone modifications in lung cells: implications for the pathogenesis of COPD and lung cancer. J Proteome Res (2013) 0.83

Methylation of histone H3K23 blocks DNA damage in pericentric heterochromatin during meiosis. Elife (2014) 0.83

Identification of phosphorylation sites in betaPIX and PAK1. J Cell Sci (2007) 0.81

Top-down protein characterization facilitated by ion/ion reactions on a quadrupole/time of flight platform. Proteomics (2010) 0.81

In vacuo formation of peptide-metal coordination complexes. Int J Mass Spectrom (2008) 0.81

Increasing peptide identifications and decreasing search times for ETD spectra by pre-processing and calculation of parent precursor charge. Proteome Sci (2012) 0.81

Ion-Ion Reactions with Fixed-Charge Modified Proteins to Produce Ions in a Single, Very High Charge State. Int J Mass Spectrom (2008) 0.80

Proteomics and systems biology for understanding diabetic nephropathy. J Cardiovasc Transl Res (2012) 0.80

Articles cited by this

Basic local alignment search tool. J Mol Biol (1990) 659.07

An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database. J Am Soc Mass Spectrom (1994) 45.51

Crystal structure of the nucleosome core particle at 2.8 A resolution. Nature (1997) 44.55

Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays. Science (2003) 16.80

Peptide and protein sequence analysis by electron transfer dissociation mass spectrometry. Proc Natl Acad Sci U S A (2004) 13.14

Function of alternative splicing. Gene (2004) 5.95

Binary switches and modification cassettes in histone biology and beyond. Nature (2003) 4.75

Novel linear quadrupole ion trap/FT mass spectrometer: performance characterization and use in the comparative analysis of histone H3 post-translational modifications. J Proteome Res (2004) 4.32

Histone H2A.Z regulats transcription and is partially redundant with nucleosome remodeling complexes. Cell (2000) 3.50

Subfemtomole MS and MS/MS peptide sequence analysis using nano-HPLC micro-ESI fourier transform ion cyclotron resonance mass spectrometry. Anal Chem (2000) 3.38

Top-down proteomics. Anal Chem (2004) 3.01

Top down characterization of larger proteins (45 kDa) by electron capture dissociation mass spectrometry. J Am Chem Soc (2002) 2.72

Assessing the impact of alternative splicing on domain interactions in the human proteome. J Proteome Res (2004) 2.71

H2A.Z alters the nucleosome surface to promote HP1alpha-mediated chromatin fiber folding. Mol Cell (2004) 2.63

Top-down mass spectrometry of a 29-kDa protein for characterization of any posttranslational modification to within one residue. Proc Natl Acad Sci U S A (2002) 2.62

Ion/ion chemistry of high-mass multiply charged ions. Mass Spectrom Rev (1999) 2.35

Gas-phase concentration, purification, and identification of whole proteins from complex mixtures. J Am Chem Soc (2002) 2.18

A histone variant, Htz1p, and a Sir1p-like protein, Esc2p, mediate silencing at HMR. Mol Cell (2000) 2.18

'Top down' protein characterization via tandem mass spectrometry. J Mass Spectrom (2002) 2.11

Secondary and tertiary structures of gaseous protein ions characterized by electron capture dissociation mass spectrometry and photofragment spectroscopy. Proc Natl Acad Sci U S A (2002) 1.85

Kinetic intermediates in the folding of gaseous protein ions characterized by electron capture dissociation mass spectrometry. J Am Chem Soc (2001) 1.75

Tandem mass spectrometry for peptide and protein sequence analysis. Biotechniques (2005) 1.70

Controlling charge states of large ions. Science (1999) 1.61

Whole protein dissociation in a quadrupole ion trap: identification of an a priori unknown modified protein. Anal Chem (2004) 1.57

Charge reduction electrospray mass spectrometry. Anal Chem (2000) 1.50

Sequence tag identification of intact proteins by matching tanden mass spectral data against sequence data bases. Proc Natl Acad Sci U S A (1996) 1.47

The enhancement of histone H4 and H2A serine 1 phosphorylation during mitosis and S-phase is evolutionarily conserved. Chromosoma (2004) 1.47

Simplification of product ion spectra derived from multiply charged parent ions via ion/ion chemistry. Anal Chem (1998) 1.47

Ion/ion proton-transfer kinetics: implications for analysis of ions derived from electrospray of protein mixtures. Anal Chem (1998) 1.43

Top down characterization of secreted proteins from Mycobacterium tuberculosis by electron capture dissociation mass spectrometry. J Am Soc Mass Spectrom (2003) 1.41

Perspectives for mass spectrometry and functional proteomics. Mass Spectrom Rev (2001) 1.33

Protein identification using 2D-LC-MS/MS. Methods (2005) 1.30

Targeted analysis and discovery of posttranslational modifications in proteins from methanogenic archaea by top-down MS. Proc Natl Acad Sci U S A (2004) 1.26

Proton transfer reaction studies of multiply charged proteins in a high mass-to-charge ratio quadrupole mass spectrometer. J Am Soc Mass Spectrom (1994) 1.26

Phosphorylation site identification via ion trap tandem mass spectrometry of whole protein and peptide ions: bovine alpha-crystallin A chain. Anal Chem (2003) 1.24

Ion/ion proton transfer reactions for protein mixture analysis. Anal Chem (1996) 1.19

The many tales of a tail: carboxyl-terminal tail heterogeneity specializes histone H2A variants for defined chromatin function. Biochemistry (2002) 1.19

Improved molecular weight-based processing of intact proteins for interrogation by quadrupole-enhanced FT MS/MS. J Proteome Res (2004) 1.01

New twists on H2A.Z: a histone variant with a controversial structural and functional past. Biochem Cell Biol (2004) 1.00

Perspectives in spicing up proteomics with splicing. Proteomics (2005) 1.00

Articles by these authors

Peptide and protein sequence analysis by electron transfer dissociation mass spectrometry. Proc Natl Acad Sci U S A (2004) 13.14

Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding. Science (2011) 9.00

Phosphoproteome analysis by mass spectrometry and its application to Saccharomyces cerevisiae. Nat Biotechnol (2002) 8.37

Histone methyltransferases direct different degrees of methylation to define distinct chromatin domains. Mol Cell (2003) 6.44

Regulation of HP1-chromatin binding by histone H3 methylation and phosphorylation. Nature (2005) 6.40

A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis. Nature (2002) 6.19

Set2 is a nucleosomal histone H3-selective methyltransferase that mediates transcriptional repression. Mol Cell Biol (2002) 5.42

Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry. Proc Natl Acad Sci U S A (2007) 5.09

Novel linear quadrupole ion trap/FT mass spectrometer: performance characterization and use in the comparative analysis of histone H3 post-translational modifications. J Proteome Res (2004) 4.32

Aurora B phosphorylates centromeric MCAK and regulates its localization and microtubule depolymerization activity. Curr Biol (2004) 4.20

Organismal differences in post-translational modifications in histones H3 and H4. J Biol Chem (2006) 3.84

Chemical derivatization of histones for facilitated analysis by mass spectrometry. Nat Protoc (2007) 3.78

Gene silencing: trans-histone regulatory pathway in chromatin. Nature (2002) 3.77

Identification of the beta cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes. Proc Natl Acad Sci U S A (2003) 3.75

A two-dimensional quadrupole ion trap mass spectrometer. J Am Soc Mass Spectrom (2002) 3.65

Supplemental activation method for high-efficiency electron-transfer dissociation of doubly protonated peptide precursors. Anal Chem (2007) 3.32

Cathepsin L proteolytically processes histone H3 during mouse embryonic stem cell differentiation. Cell (2008) 3.09

A neutral loss activation method for improved phosphopeptide sequence analysis by quadrupole ion trap mass spectrometry. Anal Chem (2004) 3.08

Expression patterns and post-translational modifications associated with mammalian histone H3 variants. J Biol Chem (2005) 3.00

The utility of ETD mass spectrometry in proteomic analysis. Biochim Biophys Acta (2006) 2.85

Extensive crosstalk between O-GlcNAcylation and phosphorylation regulates cytokinesis. Sci Signal (2010) 2.79

Recognition of a mononucleosomal histone modification pattern by BPTF via multivalent interactions. Cell (2011) 2.68

MAPKAP kinase 2 phosphorylates tristetraprolin on in vivo sites including Ser178, a site required for 14-3-3 binding. J Biol Chem (2003) 2.53

Long-distance combinatorial linkage between methylation and acetylation on histone H3 N termini. Proc Natl Acad Sci U S A (2007) 2.43

N-terminal alpha-methylation of RCC1 is necessary for stable chromatin association and normal mitosis. Nat Cell Biol (2007) 2.36

Insulin controls subcellular localization and multisite phosphorylation of the phosphatidic acid phosphatase, lipin 1. J Biol Chem (2006) 2.32

The vertebrate Ndc80 complex contains Spc24 and Spc25 homologs, which are required to establish and maintain kinetochore-microtubule attachment. Curr Biol (2004) 2.31

Mass spectrometry analysis of Arabidopsis histone H3 reveals distinct combinations of post-translational modifications. Nucleic Acids Res (2004) 2.28

O-GlcNAc regulates FoxO activation in response to glucose. J Biol Chem (2008) 2.27

Electron transfer dissociation of peptide anions. J Am Soc Mass Spectrom (2005) 2.26

RNAi-dependent H3K27 methylation is required for heterochromatin formation and DNA elimination in Tetrahymena. Genes Dev (2007) 2.26

Saccharomyces cerevisiae Rad9 acts as a Mec1 adaptor to allow Rad53 activation. Curr Biol (2005) 2.20

Androgen receptor phosphorylation. Regulation and identification of the phosphorylation sites. J Biol Chem (2002) 2.01

Genomic and functional evolution of the Drosophila melanogaster sperm proteome. Nat Genet (2006) 1.97

Phosphoproteome analysis of capacitated human sperm. Evidence of tyrosine phosphorylation of a kinase-anchoring protein 3 and valosin-containing protein/p97 during capacitation. J Biol Chem (2002) 1.96

NRMT is an alpha-N-methyltransferase that methylates RCC1 and retinoblastoma protein. Nature (2010) 1.95

Characterization of histones and their post-translational modifications by mass spectrometry. Curr Opin Chem Biol (2006) 1.92

A proteomics grade electron transfer dissociation-enabled hybrid linear ion trap-orbitrap mass spectrometer. J Proteome Res (2008) 1.92

Serine 31 phosphorylation of histone variant H3.3 is specific to regions bordering centromeres in metaphase chromosomes. Proc Natl Acad Sci U S A (2005) 1.91

Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire. Proc Natl Acad Sci U S A (2012) 1.89

Methods for analyzing peptides and proteins on a chromatographic timescale by electron-transfer dissociation mass spectrometry. Nat Protoc (2008) 1.87

Par3 controls epithelial spindle orientation by aPKC-mediated phosphorylation of apical Pins. Curr Biol (2010) 1.86

Post-acquisition ETD spectral processing for increased peptide identifications. J Am Soc Mass Spectrom (2009) 1.86

Proteome-wide prediction of acetylation substrates. Proc Natl Acad Sci U S A (2009) 1.81

A PGC-1alpha-O-GlcNAc transferase complex regulates FoxO transcription factor activity in response to glucose. J Biol Chem (2008) 1.76

Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets. Proc Natl Acad Sci U S A (2012) 1.75

Enrichment and site mapping of O-linked N-acetylglucosamine by a combination of chemical/enzymatic tagging, photochemical cleavage, and electron transfer dissociation mass spectrometry. Mol Cell Proteomics (2009) 1.72

A novel histone deacetylase pathway regulates mitosis by modulating Aurora B kinase activity. Genes Dev (2006) 1.70

Tandem mass spectrometry for peptide and protein sequence analysis. Biotechniques (2005) 1.70

Codependent functions of RSK2 and the apoptosis-promoting factor TIA-1 in stress granule assembly and cell survival. Mol Cell (2008) 1.67