Published in Circulation on July 05, 2005
Sudden unexpected death in epilepsy: risk factors and potential pathomechanisms. Nat Rev Neurol (2009) 1.97
Molecular and functional characterization of novel glycerol-3-phosphate dehydrogenase 1 like gene (GPD1-L) mutations in sudden infant death syndrome. Circulation (2007) 1.64
Genetic testing and common disorders in a public health framework: how to assess relevance and possibilities. Background Document to the ESHG recommendations on genetic testing and common disorders. Eur J Hum Genet (2011) 1.57
The molecular autopsy: should the evaluation continue after the funeral? Pediatr Cardiol (2012) 1.57
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Inherited cardiac arrhythmias: diagnosis, treatment, and prevention. Dtsch Arztebl Int (2011) 1.01
State of postmortem genetic testing known as the cardiac channel molecular autopsy in the forensic evaluation of unexplained sudden cardiac death in the young. Pacing Clin Electrophysiol (2009) 0.98
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Novel mutations in the KCND3-encoded Kv4.3 K+ channel associated with autopsy-negative sudden unexplained death. Hum Mutat (2012) 0.93
Periodical cardiovascular screening is mandatory for elite athletes. Neth Heart J (2007) 0.91
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Rationale and design of the CAREFUL study : The yield of CARdiogenetic scrEening in First degree relatives of sudden cardiac and UnexpLained death victims <45 years. Neth Heart J (2010) 0.90
Genetic screening in sudden cardiac death in the young can save future lives. Int J Legal Med (2015) 0.90
Criteria for arrhythmogenicity in genetically-modified Langendorff-perfused murine hearts modelling the congenital long QT syndrome type 3 and the Brugada syndrome. Pflugers Arch (2007) 0.89
The investigation of sudden arrhythmic death syndrome (SADS)-the current approach to family screening and the future role of genomics and stem cell technology. Front Physiol (2013) 0.86
Causes and prevention of sudden cardiac death in the elderly. Nat Rev Cardiol (2013) 0.85
Prevalence of arrhythmia-associated gene mutations and risk of sudden cardiac death in the Finnish population. Ann Med (2013) 0.85
Pediatric basic and advanced life support: 2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with Treatment Recommendations. Pediatrics (2010) 0.85
Clinical interpretation of genetic variants in arrhythmogenic right ventricular cardiomyopathy. Clin Res Cardiol (2014) 0.85
Population-based incidence of sudden cardiac and unexpected death before and after the 2011 earthquake and tsunami in Iwate, northeast Japan. J Am Heart Assoc (2014) 0.84
Sudden Cardiac Death in the Young. Circulation (2016) 0.83
Exercise: friend or foe? Nat Rev Cardiol (2013) 0.81
Evaluating the role of Cardiac Genetics Nurses in inherited cardiac conditions services using a Maturity Matrix. Eur J Cardiovasc Nurs (2013) 0.80
The molecular autopsy: an indispensable step following sudden cardiac death in the young? Herzschrittmacherther Elektrophysiol (2012) 0.80
A review of sudden unexpected death in the young in British Columbia. Can J Cardiol (2010) 0.79
Near death and neurocardiogenic syncope. Clin Auton Res (2007) 0.79
Role of congenital long-QT syndrome in unexplained sudden infant death: proposal for an electrocardiographic screening in relatives. Eur J Pediatr (2009) 0.79
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Pathogenesis and management of Brugada syndrome. Nat Rev Cardiol (2016) 0.78
Sequenom MassARRAY approach in the arrhythmogenic right ventricular cardiomyopathy post-mortem setting: clinical and forensic implications. Int J Legal Med (2014) 0.78
Family-based associations in measures of psychological distress and quality of life in a cardiac screening clinic for inheritable cardiac diseases: a cross-sectional study. BMC Med Genet (2013) 0.78
[Primary electrical heart disease in adulthood--electrophysiological findings and therapy]. Herzschrittmacherther Elektrophysiol (2005) 0.77
Vasovagal syncope or ventricular fibrillation. Your diagnosis better be accurate. Clin Auton Res (2007) 0.77
A case control study on autopsy findings in sudden unexplained nocturnal death syndrome. Heart Asia (2014) 0.76
Arrhythmias: Unexplained sudden cardiac death--back to clinical evaluation. Nat Rev Cardiol (2009) 0.76
The SPORTCOR registry: a national databank for sports cardiology. Neth Heart J (2007) 0.75
Identification of pathogenic variants in genes related to channelopathy and cardiomyopathy in Korean sudden cardiac arrest survivors. J Hum Genet (2017) 0.75
A human MYBPC3 mutation appearing about 10 centuries ago results in a hypertrophic cardiomyopathy with delayed onset, moderate evolution but with a risk of sudden death. BMC Med Genet (2012) 0.75
Sudden Unexplained Death - Treating the Family. Arrhythm Electrophysiol Rev (2014) 0.75
Molecular autopsy in victims of inherited arrhythmias. J Arrhythm (2015) 0.75
Diabetic Dead-in-Bed Syndrome: A Possible Link to a Cardiac Ion Channelopathy. Case Rep Med (2014) 0.75
Sudden cardiac death: what should we tell the family? Neth Heart J (2010) 0.75
Sudden cardiac death in young athletes. Asian J Sports Med (2011) 0.75
Inpatient detection of cardiac-inherited disease: the impact of improving family history taking. Open Heart (2016) 0.75
Sudden arrhythmic death syndrome. Heart (2007) 0.75
Should I be worried? Neth Heart J (2006) 0.75
Preventing sudden cardiac death in the young: Is electrocardiogram screening the most effective means? Paediatr Child Health (2009) 0.75
Assessing the knowledge of sudden unexpected death in the young among Canadian medical students and recent graduates: a cross-sectional study. BMJ Open (2012) 0.75
Sudden cardiac death, aborted, in healthy 34-year-old male. J Family Med Prim Care (2014) 0.75
Family History of Sudden Cardiac Death of the Young: Prevalence and Associated Factors. Healthcare (Basel) (2015) 0.75
Genetic analysis of Iranian family with hereditary cardiac arrhythmias by next generation sequencing. Adv Biomed Res (2016) 0.75
Soccer and Sudden Cardiac Death in Young Competitive Athletes: A Review. J Sports Med (Hindawi Publ Corp) (2013) 0.75
Risk stratification in young patients with channelopathies. Indian Pacing Electrophysiol J (2010) 0.75
Radiofrequency Ablation to Prevent Sudden Cardiac Death. Methodist Debakey Cardiovasc J (2015) 0.75
Genetic Basis of Ventricular Arrhythmias. Curr Cardiovasc Risk Rep (2010) 0.75
Medico-legal perspectives on sudden cardiac death in young athletes. Int J Legal Med (2016) 0.75
Molecular investigation by whole exome sequencing revealed a high proportion of pathogenic variants among Thai victims of sudden unexpected death syndrome. PLoS One (2017) 0.75
Sudden cardiac death in the young: how can disease recognition and prevention in family members be improved? Herzschrittmacherther Elektrophysiol (2012) 0.75
[Genetic testing in hereditary arrythmia syndromes today and in the future]. Herzschrittmacherther Elektrophysiol (2012) 0.75
An international compendium of mutations in the SCN5A-encoded cardiac sodium channel in patients referred for Brugada syndrome genetic testing. Heart Rhythm (2009) 4.99
Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies. Lancet (2012) 4.63
MiR423-5p as a circulating biomarker for heart failure. Circ Res (2010) 3.83
Plakophilin-2 mutations are the major determinant of familial arrhythmogenic right ventricular dysplasia/cardiomyopathy. Circulation (2006) 3.44
Flecainide prevents catecholaminergic polymorphic ventricular tachycardia in mice and humans. Nat Med (2009) 3.35
Right ventricular fibrosis and conduction delay in a patient with clinical signs of Brugada syndrome: a combined electrophysiological, genetic, histopathologic, and computational study. Circulation (2005) 3.30
Genetic testing for long-QT syndrome: distinguishing pathogenic mutations from benign variants. Circulation (2009) 3.11
Presence of older thrombus is an independent predictor of long-term mortality in patients with ST-elevation myocardial infarction treated with thrombus aspiration during primary percutaneous coronary intervention. Circulation (2008) 2.96
Clinical aspects of type-1 long-QT syndrome by location, coding type, and biophysical function of mutations involving the KCNQ1 gene. Circulation (2007) 2.88
Thoracoscopic video-assisted pulmonary vein antrum isolation, ganglionated plexus ablation, and periprocedural confirmation of ablation lesions: first results of a hybrid surgical-electrophysiological approach for atrial fibrillation. Circ Arrhythm Electrophysiol (2011) 2.84
Mutation in the KCNQ1 gene leading to the short QT-interval syndrome. Circulation (2004) 2.82
Spectrum and prevalence of mutations from the first 2,500 consecutive unrelated patients referred for the FAMILION long QT syndrome genetic test. Heart Rhythm (2009) 2.81
Common sodium channel promoter haplotype in asian subjects underlies variability in cardiac conduction. Circulation (2006) 2.72
Neutrophil infiltration of culprit lesions in acute coronary syndromes. Circulation (2002) 2.67
Absence of calsequestrin 2 causes severe forms of catecholaminergic polymorphic ventricular tachycardia. Circ Res (2002) 2.66
Genotype-phenotype aspects of type 2 long QT syndrome. J Am Coll Cardiol (2009) 2.65
Familial sudden death is an important risk factor for primary ventricular fibrillation: a case-control study in acute myocardial infarction patients. Circulation (2006) 2.63
Relationship of thrombus healing to underlying plaque morphology in sudden coronary death. J Am Coll Cardiol (2009) 2.59
Genotype-phenotype relationship in Brugada syndrome: electrocardiographic features differentiate SCN5A-related patients from non-SCN5A-related patients. J Am Coll Cardiol (2002) 2.58
The response of the QT interval to the brief tachycardia provoked by standing: a bedside test for diagnosing long QT syndrome. J Am Coll Cardiol (2010) 2.56
Diagnostic criteria for congenital long QT syndrome in the era of molecular genetics: do we need a scoring system? Eur Heart J (2006) 2.54
Sodium channel β1 subunit mutations associated with Brugada syndrome and cardiac conduction disease in humans. J Clin Invest (2008) 2.54
A gain-of-function TBX5 mutation is associated with atypical Holt-Oram syndrome and paroxysmal atrial fibrillation. Circ Res (2008) 2.39
Disruption of Abcc6 in the mouse: novel insight in the pathogenesis of pseudoxanthoma elasticum. Hum Mol Genet (2005) 2.36
Distinguishing arrhythmogenic right ventricular cardiomyopathy/dysplasia-associated mutations from background genetic noise. J Am Coll Cardiol (2011) 2.31
Genetic variation in SCN10A influences cardiac conduction. Nat Genet (2010) 2.30
Unmasking of brugada syndrome by lithium. Circulation (2005) 2.30
Impact of genetics on the clinical management of channelopathies. J Am Coll Cardiol (2013) 2.30
Clinical aspects and prognosis of Brugada syndrome in children. Circulation (2007) 2.29
Risk factors for malignant ventricular arrhythmias in lamin a/c mutation carriers a European cohort study. J Am Coll Cardiol (2012) 2.28
A mutation in the human cardiac sodium channel (E161K) contributes to sick sinus syndrome, conduction disease and Brugada syndrome in two families. J Mol Cell Cardiol (2005) 2.21
Risk for life-threatening cardiac events in patients with genotype-confirmed long-QT syndrome and normal-range corrected QT intervals. J Am Coll Cardiol (2011) 2.15
A cardiac sodium channel mutation cosegregates with a rare connexin40 genotype in familial atrial standstill. Circ Res (2003) 2.15
Contribution of sodium channel mutations to bradycardia and sinus node dysfunction in LQT3 families. Circ Res (2003) 2.14
Inaccessibility to quinidine therapy is about to get worse. J Am Coll Cardiol (2013) 2.12
Activation delay and VT parameters in arrhythmogenic right ventricular dysplasia/cardiomyopathy: toward improvement of diagnostic ECG criteria. J Cardiovasc Electrophysiol (2008) 2.09
Pathophysiological mechanisms of Brugada syndrome: depolarization disorder, repolarization disorder, or more? Cardiovasc Res (2005) 2.06
Homozygous and compound heterozygous mutations in ZMPSTE24 cause the laminopathy restrictive dermopathy. J Invest Dermatol (2005) 2.06
Active cascade screening in primary inherited arrhythmia syndromes: does it lead to prophylactic treatment? J Am Coll Cardiol (2010) 2.06
Brugada syndrome. Circ Arrhythm Electrophysiol (2012) 2.03
Con: Newborn screening to prevent sudden cardiac death? Heart Rhythm (2006) 2.02
Role of programmed ventricular stimulation in patients with Brugada syndrome: a meta-analysis of worldwide published data. Eur Heart J (2007) 1.98
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. Am J Hum Genet (2012) 1.96
The Brugada ECG pattern: a marker of channelopathy, structural heart disease, or neither? Toward a unifying mechanism of the Brugada syndrome. Circ Arrhythm Electrophysiol (2010) 1.96
The entirely subcutaneous implantable cardioverter-defibrillator: initial clinical experience in a large Dutch cohort. J Am Coll Cardiol (2012) 1.93
Permanent leadless cardiac pacing: results of the LEADLESS trial. Circulation (2014) 1.93
Drugs and Brugada syndrome patients: review of the literature, recommendations, and an up-to-date website (www.brugadadrugs.org). Heart Rhythm (2009) 1.92
Incidence, causes, and outcomes of out-of-hospital cardiac arrest in children. A comprehensive, prospective, population-based study in the Netherlands. J Am Coll Cardiol (2011) 1.92
Phylogenetic and physicochemical analyses enhance the classification of rare nonsynonymous single nucleotide variants in type 1 and 2 long-QT syndrome. Circ Cardiovasc Genet (2012) 1.91
Long QT syndrome caused by a large duplication in the KCNH2 (HERG) gene undetectable by current polymerase chain reaction-based exon-scanning methodologies. Heart Rhythm (2006) 1.90
Mutations in cytoplasmic loops of the KCNQ1 channel and the risk of life-threatening events: implications for mutation-specific response to β-blocker therapy in type 1 long-QT syndrome. Circulation (2012) 1.89
A common polymorphism in KCNH2 (HERG) hastens cardiac repolarization. Cardiovasc Res (2003) 1.89
A new ECG sign of proximal LAD occlusion. N Engl J Med (2008) 1.89
Flecainide therapy reduces exercise-induced ventricular arrhythmias in patients with catecholaminergic polymorphic ventricular tachycardia. J Am Coll Cardiol (2011) 1.89
Desmin mutations as a cause of right ventricular heart failure affect the intercalated disks. Heart Rhythm (2010) 1.85
A calcium sensor in the sodium channel modulates cardiac excitability. Nature (2002) 1.83
Compound heterozygosity for mutations (W156X and R225W) in SCN5A associated with severe cardiac conduction disturbances and degenerative changes in the conduction system. Circ Res (2003) 1.82
Not all beta-blockers are equal in the management of long QT syndrome types 1 and 2: higher recurrence of events under metoprolol. J Am Coll Cardiol (2012) 1.81
Long-term prognosis of individuals with right precordial ST-segment-elevation Brugada syndrome. Circulation (2005) 1.78
Overlap syndrome of cardiac sodium channel disease in mice carrying the equivalent mutation of human SCN5A-1795insD. Circulation (2006) 1.76
Epidemiologic, molecular, and functional evidence suggest A572D-SCN5A should not be considered an independent LQT3-susceptibility mutation. Heart Rhythm (2010) 1.76
Expanding spectrum of human RYR2-related disease: new electrocardiographic, structural, and genetic features. Circulation (2007) 1.74
Brugada phenocopy: new terminology and proposed classification. Ann Noninvasive Electrocardiol (2012) 1.74
Mechanism of right precordial ST-segment elevation in structural heart disease: excitation failure by current-to-load mismatch. Heart Rhythm (2009) 1.73
Local depolarization abnormalities are the dominant pathophysiologic mechanism for type 1 electrocardiogram in brugada syndrome a study of electrocardiograms, vectorcardiograms, and body surface potential maps during ajmaline provocation. J Am Coll Cardiol (2010) 1.71
Irreversible electroporation: just another form of thermal therapy? Prostate (2014) 1.71
Cardiac sodium channel overlap syndromes: different faces of SCN5A mutations. Trends Cardiovasc Med (2008) 1.68
The diagnostic and therapeutic aspects of loss-of-function cardiac sodium channelopathies in children. Heart Rhythm (2012) 1.66
Value of history-taking in syncope patients: in whom to suspect long QT syndrome? Europace (2009) 1.65
SCN5A mutations and the role of genetic background in the pathophysiology of Brugada syndrome. Circ Cardiovasc Genet (2009) 1.64
Structural abnormalities of the inferoseptal left ventricular wall detected by cardiac magnetic resonance imaging in carriers of hypertrophic cardiomyopathy mutations. J Am Coll Cardiol (2006) 1.63
Recurrent intrauterine fetal loss due to near absence of HERG: clinical and functional characterization of a homozygous nonsense HERG Q1070X mutation. Heart Rhythm (2008) 1.62
Delay in right ventricular activation contributes to Brugada syndrome. Circulation (2004) 1.61
The common long-QT syndrome mutation KCNQ1/A341V causes unusually severe clinical manifestations in patients with different ethnic backgrounds: toward a mutation-specific risk stratification. Circulation (2007) 1.58
Genetic testing and common disorders in a public health framework: how to assess relevance and possibilities. Background Document to the ESHG recommendations on genetic testing and common disorders. Eur J Hum Genet (2011) 1.57
Arrhythmogenic right ventricular cardiomyopathy due to a novel plakophilin 2 mutation: wide spectrum of disease in mutation carriers within a family. Heart Rhythm (2006) 1.57
Type of SCN5A mutation determines clinical severity and degree of conduction slowing in loss-of-function sodium channelopathies. Heart Rhythm (2008) 1.56
A family with Andersen-Tawil syndrome and dilated cardiomyopathy. Heart Rhythm (2006) 1.56
Desmoglein-2 and desmocollin-2 mutations in dutch arrhythmogenic right ventricular dysplasia/cardiomypathy patients: results from a multicenter study. Circ Cardiovasc Genet (2009) 1.54
Mutation and gender-specific risk in type 2 long QT syndrome: implications for risk stratification for life-threatening cardiac events in patients with long QT syndrome. Heart Rhythm (2011) 1.54
In silico cardiac risk assessment in patients with long QT syndrome: type 1: clinical predictability of cardiac models. J Am Coll Cardiol (2012) 1.53
Cardiomyocytes derived from pluripotent stem cells recapitulate electrophysiological characteristics of an overlap syndrome of cardiac sodium channel disease. Circulation (2012) 1.53
Low numbers of FOXP3 positive regulatory T cells are present in all developmental stages of human atherosclerotic lesions. PLoS One (2007) 1.51
Phospholamban R14del mutation in patients diagnosed with dilated cardiomyopathy or arrhythmogenic right ventricular cardiomyopathy: evidence supporting the concept of arrhythmogenic cardiomyopathy. Eur J Heart Fail (2012) 1.51
Microvolt T-wave alternans during exercise and pacing are not comparable. Europace (2009) 1.49