Published in BMC Genet on July 18, 2005
Dietary xenosterols lead to infertility and loss of abdominal adipose tissue in sterolin-deficient mice. J Lipid Res (2012) 0.84
Dietary phytosterols and phytostanols decrease cholesterol levels but increase blood pressure in WKY inbred rats in the absence of salt-loading. Nutr Metab (Lond) (2010) 0.84
Kinetics of phytosterol metabolism in neonates receiving parenteral nutrition. Pediatr Res (2015) 0.75
Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters. Science (2000) 6.73
Identification of Cd36 (Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats. Nat Genet (1999) 4.48
Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol. J Clin Invest (2002) 3.85
Regulation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors alpha and beta. J Biol Chem (2002) 3.52
Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion. Proc Natl Acad Sci U S A (2002) 3.09
Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption. Nat Genet (2001) 2.84
ABCG5 and ABCG8 are obligate heterodimers for protein trafficking and biliary cholesterol excretion. J Biol Chem (2003) 2.48
Two genes that map to the STSL locus cause sitosterolemia: genomic structure and spectrum of mutations involving sterolin-1 and sterolin-2, encoded by ABCG5 and ABCG8, respectively. Am J Hum Genet (2001) 2.08
Coexpression of ATP-binding cassette proteins ABCG5 and ABCG8 permits their transport to the apical surface. J Clin Invest (2002) 2.02
New target regions for human hypertension via comparative genomics. Genome Res (2000) 1.75
Expression of ABCG5 and ABCG8 is required for regulation of biliary cholesterol secretion. J Biol Chem (2004) 1.57
Mapping a gene involved in regulating dietary cholesterol absorption. The sitosterolemia locus is found at chromosome 2p21. J Clin Invest (1998) 1.55
Genetic basis of sitosterolemia. Curr Opin Lipidol (2001) 1.48
A mouse model of sitosterolemia: absence of Abcg8/sterolin-2 results in failure to secrete biliary cholesterol. BMC Med (2004) 1.28
Techniques for the collection of lymph from the liver, small intestine, or thoracic duct of the rat. J Lab Clin Med (1948) 1.27
Comparison of intestinal absorption of cholesterol with different plant sterols in man. Eur J Clin Invest (1993) 1.15
Vegetable oils high in phytosterols make erythrocytes less deformable and shorten the life span of stroke-prone spontaneously hypertensive rats. J Nutr (2000) 1.14
Molecular cloning, genomic organization, genetic variations, and characterization of murine sterolin genes Abcg5 and Abcg8. J Lipid Res (2002) 1.13
Molecular evidence of genetic heterogeneity in Wistar-Kyoto rats: implications for research with the spontaneously hypertensive rat. Hypertension (1989) 1.12
Trafficking of canalicular ABC transporters in hepatocytes. Annu Rev Physiol (2002) 1.09
Loci on chromosomes 14 and 2, distinct from ABCG5/ABCG8, regulate plasma plant sterol levels in a C57BL/6J x CASA/Rk intercross. Proc Natl Acad Sci U S A (2002) 1.06
High-resolution physical and transcript map of human chromosome 2p21 containing the sitosterolaemia locus. Eur J Hum Genet (2001) 1.01
Localization of ABCG5 and ABCG8 proteins in human liver, gall bladder and intestine. BMC Gastroenterol (2004) 0.95
A missense mutation in kynurenine aminotransferase-1 in spontaneously hypertensive rats. J Biol Chem (2002) 0.93
Influence of sources of dietary oils on the life span of stroke-prone spontaneously hypertensive rats. Lipids (2000) 0.93
ABCG5 and ABCG8 are expressed in gallbladder epithelial cells. Biochem Biophys Res Commun (2003) 0.90
Phytosterol additives increase blood pressure and promote stroke onset in salt-loaded stroke-prone spontaneously hypertensive rats. Clin Exp Pharmacol Physiol (2003) 0.90
Thirteen-week dietary intake of rapeseed oil or soybean oil as the only dietary fat in Wistar Kyoto rats-change in blood pressure. Food Chem Toxicol (2000) 0.89
Diosgenin-induced biliary cholesterol secretion in mice requires Abcg8. Hepatology (2005) 0.88
The rat STSL locus: characterization, chromosomal assignment, and genetic variations in sitosterolemic hypertensive rats. BMC Cardiovasc Disord (2003) 0.86
A missense mutation in the Abcg5 gene causes phytosterolemia in SHR, stroke-prone SHR, and WKY rats. J Lipid Res (2003) 0.84
Genetic regulation of cholesterol absorption and plasma plant sterol levels: commonalities and differences. J Lipid Res (2003) 0.83
Identification of a mutation in ADD1/SREBP-1 in the spontaneously hypertensive rat. Mamm Genome (2001) 0.82
Blood coagulation and osmolar tolerance of erythrocytes in stroke-prone spontaneously hypertensive rats given rapeseed oil or soybean oil as the only dietary fat. Toxicol Lett (2000) 0.80
Dietary intake of rapeseed oil or soybean oil as the only fat nutrient in spontaneously hypertensive rats and Wistar Kyoto rats - blood pressure and pathophysiology. Toxicology (2000) 0.80
Mechanisms of phytosterolemia in stroke-prone spontaneously hypertensive and WKY rats. Metabolism (2001) 0.78
HIF-2alpha regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth. Genes Dev (2006) 5.15
FoxO1 regulates multiple metabolic pathways in the liver: effects on gluconeogenic, glycolytic, and lipogenic gene expression. J Biol Chem (2006) 3.35
Acute toxicity and biodistribution of different sized titanium dioxide particles in mice after oral administration. Toxicol Lett (2006) 3.06
A controlled high-fat diet induces an obese syndrome in rats. J Nutr (2003) 2.80
Human cholesterol 7alpha-hydroxylase (CYP7A1) deficiency has a hypercholesterolemic phenotype. J Clin Invest (2002) 2.12
Phase III trial of ursodeoxycholic acid to prevent colorectal adenoma recurrence. J Natl Cancer Inst (2005) 2.12
CD36 deficiency impairs intestinal lipid secretion and clearance of chylomicrons from the blood. J Clin Invest (2005) 2.04
A novel, noninvasive method for the measurement of intestinal fat absorption. Gastroenterology (2004) 2.02
Cerebrotendinous xanthomatosis: a rare disease with diverse manifestations. Arch Neurol (2002) 1.94
Complex inheritance of familial hypercholanemia with associated mutations in TJP2 and BAAT. Nat Genet (2003) 1.85
Splenic injury as a complication of colonoscopy: a case series. Am J Gastroenterol (2009) 1.83
Effects of permissive hypercapnia on transient global cerebral ischemia-reperfusion injury in rats. Anesthesiology (2010) 1.78
CD36 is important for chylomicron formation and secretion and may mediate cholesterol uptake in the proximal intestine. Gastroenterology (2006) 1.67
Selective deficits in the omega-3 fatty acid docosahexaenoic acid in the postmortem orbitofrontal cortex of patients with major depressive disorder. Biol Psychiatry (2006) 1.67
Apolipoprotein A-IV inhibits experimental colitis. J Clin Invest (2004) 1.66
Docosahexaenoic acid supplementation increases prefrontal cortex activation during sustained attention in healthy boys: a placebo-controlled, dose-ranging, functional magnetic resonance imaging study. Am J Clin Nutr (2010) 1.66
Sleeve gastrectomy in rats improves postprandial lipid clearance by reducing intestinal triglyceride secretion. Gastroenterology (2011) 1.64
Duodenal-jejunal exclusion improves glucose tolerance in the diabetic, Goto-Kakizaki rat by a GLP-1 receptor-mediated mechanism. J Gastrointest Surg (2009) 1.54
Intestinal adaptation after ileal interposition surgery increases bile acid recycling and protects against obesity-related comorbidities. Am J Physiol Gastrointest Liver Physiol (2010) 1.54
Brain glucose metabolism controls the hepatic secretion of triglyceride-rich lipoproteins. Nat Med (2007) 1.51
Omega-3 fatty acid deficiency increases stearoyl-CoA desaturase expression and activity indices in rat liver: positive association with non-fasting plasma triglyceride levels. Prostaglandins Leukot Essent Fatty Acids (2011) 1.46
The von Hippel-Lindau Chuvash mutation promotes pulmonary hypertension and fibrosis in mice. J Clin Invest (2010) 1.46
Consumption of a high-fat diet alters the homeostatic regulation of energy balance. Physiol Behav (2004) 1.43
Structures of two coronavirus main proteases: implications for substrate binding and antiviral drug design. J Virol (2007) 1.41
GATA4 is essential for jejunal function in mice. Gastroenterology (2008) 1.39
The use of the Dhcr7 knockout mouse to accurately determine the origin of fetal sterols. J Lipid Res (2006) 1.34
Colesevelam improves insulin resistance in a diet-induced obesity (F-DIO) rat model by increasing the release of GLP-1. Am J Physiol Gastrointest Liver Physiol (2009) 1.31
Targeted ablation of glucose-dependent insulinotropic polypeptide-producing cells in transgenic mice reduces obesity and insulin resistance induced by a high fat diet. J Biol Chem (2008) 1.31
Pseudomonas aeruginosa biofilm infections in cystic fibrosis: insights into pathogenic processes and treatment strategies. Expert Opin Ther Targets (2010) 1.29
A mouse model of sitosterolemia: absence of Abcg8/sterolin-2 results in failure to secrete biliary cholesterol. BMC Med (2004) 1.28
Fasting and postprandial concentrations of GLP-1 in intestinal lymph and portal plasma: evidence for selective release of GLP-1 in the lymph system. Am J Physiol Regul Integr Comp Physiol (2007) 1.27
Cross-sectional analysis of clinical and environmental isolates of Pseudomonas aeruginosa: biofilm formation, virulence, and genome diversity. Infect Immun (2004) 1.27
Reduced absorption of saturated fatty acids and resistance to diet-induced obesity and diabetes by ezetimibe-treated and Npc1l1-/- mice. Am J Physiol Gastrointest Liver Physiol (2008) 1.26
Hypercholesterolemia and changes in lipid and bile acid metabolism in male and female cyp7A1-deficient mice. J Lipid Res (2003) 1.24
Mechanisms of oleoylethanolamide-induced changes in feeding behavior and motor activity. Am J Physiol Regul Integr Comp Physiol (2005) 1.23
Selective deficits in erythrocyte docosahexaenoic acid composition in adult patients with bipolar disorder and major depressive disorder. J Affect Disord (2010) 1.23
Assessment of feeding behavior in laboratory mice. Cell Metab (2010) 1.22
CYP3A4 is a human microsomal vitamin D 25-hydroxylase. J Bone Miner Res (2003) 1.19
The roles of serum selenium and selenoproteins on mercury toxicity in environmental and occupational exposure. Environ Health Perspect (2006) 1.19
GLP-1 reduces intestinal lymph flow, triglyceride absorption, and apolipoprotein production in rats. Am J Physiol Gastrointest Liver Physiol (2005) 1.18
Why does the gut choose apolipoprotein B48 but not B100 for chylomicron formation? Am J Physiol Gastrointest Liver Physiol (2007) 1.18
Gene therapy in a humanized mouse model of familial hypercholesterolemia leads to marked regression of atherosclerosis. PLoS One (2010) 1.18
Deficits in docosahexaenoic acid and associated elevations in the metabolism of arachidonic acid and saturated fatty acids in the postmortem orbitofrontal cortex of patients with bipolar disorder. Psychiatry Res (2008) 1.17
Antiobesity and antihyperglycemic effects of ginsenoside Rb1 in rats. Diabetes (2010) 1.15
A transmission disequilibrium test for general pedigrees that is robust to the presence of random genotyping errors and any number of untyped parents. Eur J Hum Genet (2004) 1.13
Molecular cloning, genomic organization, genetic variations, and characterization of murine sterolin genes Abcg5 and Abcg8. J Lipid Res (2002) 1.13
A three-dimensional homology model of lipid-free apolipoprotein A-IV using cross-linking and mass spectrometry. J Biol Chem (2008) 1.10
Characterization of mice lacking the gene for cholecystokinin. Am J Physiol Regul Integr Comp Physiol (2007) 1.09
Effects of yo-yo diet, caloric restriction, and olestra on tissue distribution of hexachlorobenzene. Am J Physiol Gastrointest Liver Physiol (2004) 1.09
Apolipoprotein A-IV improves glucose homeostasis by enhancing insulin secretion. Proc Natl Acad Sci U S A (2012) 1.08
Stimulation of incretin secretion by dietary lipid: is it dose dependent? Am J Physiol Gastrointest Liver Physiol (2009) 1.08
Consumption of a high-fat diet induces central insulin resistance independent of adiposity. Physiol Behav (2011) 1.07
Gender differences in rat erythrocyte and brain docosahexaenoic acid composition: role of ovarian hormones and dietary omega-3 fatty acid composition. Psychoneuroendocrinology (2008) 1.07
Inhibition of ileal bile acid transport lowers plasma cholesterol levels by inactivating hepatic farnesoid X receptor and stimulating cholesterol 7 alpha-hydroxylase. Metabolism (2004) 1.07
Loci on chromosomes 14 and 2, distinct from ABCG5/ABCG8, regulate plasma plant sterol levels in a C57BL/6J x CASA/Rk intercross. Proc Natl Acad Sci U S A (2002) 1.06
The regulation of the lymphatic secretion of glucagon-like peptide-1 (GLP-1) by intestinal absorption of fat and carbohydrate. Am J Physiol Gastrointest Liver Physiol (2007) 1.04
Increased neonatal mortality in mice lacking cellular retinol-binding protein II. J Biol Chem (2002) 1.04
The mechanism of the formation and secretion of chylomicrons. Atheroscler Suppl (2010) 1.04
Antioxidative function and biodistribution of [Gd@C82(OH)22]n nanoparticles in tumor-bearing mice. Biochem Pharmacol (2006) 1.03
Expression of biologically active rat apolipoprotein AIV in Escherichia coli. Physiol Behav (2003) 1.02
Angiotensin I is largely converted to angiotensin (1-7) and angiotensin (2-10) by isolated rat glomeruli. Hypertension (2009) 1.02
Bypassing the duodenum does not improve insulin resistance associated with diet-induced obesity in rodents. Obesity (Silver Spring) (2010) 1.02
Apolipoprotein A-IV regulates chylomicron metabolism-mechanism and function. Am J Physiol Gastrointest Liver Physiol (2011) 1.01
Treatment with a dietary fat substitute decreased Arochlor 1254 contamination in an obese diabetic male. J Nutr Biochem (2005) 1.01
Identification of an endogenous ligand that activates pregnane X receptor-mediated sterol clearance. Proc Natl Acad Sci U S A (2003) 1.01
Bile salt-stimulated carboxyl ester lipase influences lipoprotein assembly and secretion in intestine: a process mediated via ceramide hydrolysis. J Biol Chem (2001) 1.01
Diurnal rhythm of apolipoprotein A-IV in rat hypothalamus and its relation to food intake and corticosterone. Endocrinology (2004) 1.00
Modulation of apolipoprotein A-IV lipid binding by an interaction between the N and C termini. J Biol Chem (2007) 1.00
Hypothalamic apolipoprotein A-IV is regulated by leptin. Endocrinology (2007) 1.00
Using the lymph fistula rat model to study the potentiation of GIP secretion by the ingestion of fat and glucose. Am J Physiol Gastrointest Liver Physiol (2008) 1.00
Substrate specificities of rat oatp1 and ntcp: implications for hepatic organic anion uptake. Am J Physiol Gastrointest Liver Physiol (2003) 0.99
FXR-activating ligands inhibit rabbit ASBT expression via FXR-SHP-FTF cascade. Am J Physiol Gastrointest Liver Physiol (2005) 0.99
The aging human orbitofrontal cortex: decreasing polyunsaturated fatty acid composition and associated increases in lipogenic gene expression and stearoyl-CoA desaturase activity. Prostaglandins Leukot Essent Fatty Acids (2008) 0.99
Abnormalities in the fatty acid composition of the postmortem orbitofrontal cortex of schizophrenic patients: gender differences and partial normalization with antipsychotic medications. Schizophr Res (2007) 0.99
Role of CYP27A in cholesterol and bile acid metabolism. J Lipid Res (2004) 0.99
Direct injection into the dorsal root ganglion: technical, behavioral, and histological observations. J Neurosci Methods (2011) 0.98
Characterization of apolipoprotein A-IV in brain areas involved in energy homeostasis. Physiol Behav (2008) 0.98
Quantifying anomalous intestinal sterol uptake, lymphatic transport, and biliary secretion in Abcg8(-/-) mice. Hepatology (2007) 0.98
Identification of a putative nuclear localization sequence within ANG II AT(1A) receptor associated with nuclear activation. Am J Physiol Cell Physiol (2006) 0.98
Differential effects of antipsychotic medications on polyunsaturated fatty acid biosynthesis in rats: Relationship with liver delta6-desaturase expression. Schizophr Res (2011) 0.98
Brain apolipoprotein E: an important regulator of food intake in rats. Diabetes (2008) 0.97
Stigmasterol reduces plasma cholesterol levels and inhibits hepatic synthesis and intestinal absorption in the rat. Metabolism (2006) 0.97
Preclinical evaluation of a clinical candidate AAV8 vector for ornithine transcarbamylase (OTC) deficiency reveals functional enzyme from each persisting vector genome. Mol Genet Metab (2011) 0.96
Specific sequences in the N and C termini of apolipoprotein A-IV modulate its conformation and lipid association. J Biol Chem (2005) 0.96
Structure of human apolipoprotein A-IV: a distinct domain architecture among exchangeable apolipoproteins with potential functional implications. Biochemistry (2004) 0.96
The structure of dimeric apolipoprotein A-IV and its mechanism of self-association. Structure (2012) 0.95
Liver transplantation in a patient with sitosterolemia and cirrhosis. Gastroenterology (2006) 0.95
Localization of ABCG5 and ABCG8 proteins in human liver, gall bladder and intestine. BMC Gastroenterol (2004) 0.95