Published in Neuron on July 21, 2005
Aggressive pancreatic ductal adenocarcinoma in mice caused by pancreas-specific blockade of transforming growth factor-beta signaling in cooperation with active Kras expression. Genes Dev (2006) 3.16
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GABAergic neuron specification in the spinal cord, the cerebellum, and the cochlear nucleus. Neural Plast (2012) 0.81
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SMAD4 is essential for generating subtypes of neurons during cerebellar development. Dev Biol (2012) 0.80
Deregulated proliferation and differentiation in brain tumors. Cell Tissue Res (2014) 0.80
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Distinct enhancers of ptf1a mediate specification and expansion of ventral pancreas in zebrafish. Dev Biol (2013) 0.80
Cerebellar granule cell replenishment postinjury by adaptive reprogramming of Nestin(+) progenitors. Nat Neurosci (2017) 0.80
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GLUT2-mediated glucose uptake and availability are required for embryonic brain development in zebrafish. J Cereb Blood Flow Metab (2014) 0.79
Hypoxic preconditioning differentially affects GABAergic and glutamatergic neuronal cells in the injured cerebellum of the neonatal rat. PLoS One (2014) 0.79
Signals that regulate the oncogenic fate of neural stem cells and progenitors. Exp Neurol (2013) 0.79
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En1 directs superior olivary complex neuron positioning, survival, and expression of FoxP1. Dev Biol (2015) 0.78
From induction to conduction: how intrinsic transcriptional priming of extrinsic neuronal connectivity shapes neuronal identity. Open Biol (2014) 0.77
Tfap2a and 2b act downstream of Ptf1a to promote amacrine cell differentiation during retinogenesis. Mol Brain (2015) 0.77
Widespread transcription at neuronal activity-regulated enhancers. Nature (2010) 16.52
Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse. Cancer Cell (2003) 15.43
Neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker for acute renal injury after cardiac surgery. Lancet (2005) 13.77
The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors. Nat Genet (2002) 8.28
Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease. Nat Genet (2009) 8.11
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The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth. J Clin Invest (2002) 4.05
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Association between increases in urinary neutrophil gelatinase-associated lipocalin and acute renal dysfunction after adult cardiac surgery. Anesthesiology (2006) 3.66
A vasculature-associated niche for undifferentiated spermatogonia in the mouse testis. Science (2007) 3.60
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An iron delivery pathway mediated by a lipocalin. Mol Cell (2002) 3.38
Identification of Sox9-dependent acinar-to-ductal reprogramming as the principal mechanism for initiation of pancreatic ductal adenocarcinoma. Cancer Cell (2012) 3.36
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Conditional inactivation of the TGF-beta type II receptor using Cre:Lox. Genesis (2002) 3.21
The Ngal reporter mouse detects the response of the kidney to injury in real time. Nat Med (2011) 3.20
Aggressive pancreatic ductal adenocarcinoma in mice caused by pancreas-specific blockade of transforming growth factor-beta signaling in cooperation with active Kras expression. Genes Dev (2006) 3.16
Klotho, a gene related to a syndrome resembling human premature aging, functions in a negative regulatory circuit of vitamin D endocrine system. Mol Endocrinol (2003) 3.15
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Neutrophil gelatinase-associated lipocalin: a novel early urinary biomarker for cisplatin nephrotoxicity. Am J Nephrol (2004) 2.91
Results of a multicenter study of 1,057 cases of rectal cancer treated by laparoscopic surgery. Surg Endosc (2008) 2.88
Reduction in pancreatic transcription factor PDX-1 impairs glucose-stimulated insulin secretion. J Biol Chem (2002) 2.87
Irinotecan plus S-1 (IRIS) versus fluorouracil and folinic acid plus irinotecan (FOLFIRI) as second-line chemotherapy for metastatic colorectal cancer: a randomised phase 2/3 non-inferiority study (FIRIS study). Lancet Oncol (2010) 2.73
The CB1 cannabinoid receptor is the major cannabinoid receptor at excitatory presynaptic sites in the hippocampus and cerebellum. J Neurosci (2006) 2.66
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Complementary roles of cholecystokinin- and parvalbumin-expressing GABAergic neurons in hippocampal network oscillations. J Neurosci (2005) 2.64
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Cbln1 is essential for synaptic integrity and plasticity in the cerebellum. Nat Neurosci (2005) 2.29
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Ptf1a determines horizontal and amacrine cell fates during mouse retinal development. Development (2006) 2.09
Overexpression of CNP in chondrocytes rescues achondroplasia through a MAPK-dependent pathway. Nat Med (2003) 2.09
Iron traffics in circulation bound to a siderocalin (Ngal)-catechol complex. Nat Chem Biol (2010) 2.06
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Natriuretic peptides/cGMP/cGMP-dependent protein kinase cascades promote muscle mitochondrial biogenesis and prevent obesity. Diabetes (2009) 2.03
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Distinct functions of kainate receptors in the brain are determined by the auxiliary subunit Neto1. Nat Neurosci (2011) 2.00
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Regulation of osteoclast differentiation and function by the CaMK-CREB pathway. Nat Med (2006) 1.93
Impaired CNS leptin action is implicated in depression associated with obesity. Endocrinology (2011) 1.92
Ptf1a determines GABAergic over glutamatergic neuronal cell fate in the spinal cord dorsal horn. Development (2005) 1.90
Mediation of unusually high concentrations of 1,25-dihydroxyvitamin D in homozygous klotho mutant mice by increased expression of renal 1alpha-hydroxylase gene. Endocrinology (2002) 1.90
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Urinary neutrophil gelatinase-associated lipocalin levels reflect damage to glomeruli, proximal tubules, and distal nephrons. Kidney Int (2008) 1.85
Origin of climbing fiber neurons and their developmental dependence on Ptf1a. J Neurosci (2007) 1.84
Spatiotemporal patterns of multipotentiality in Ptf1a-expressing cells during pancreas organogenesis and injury-induced facultative restoration. Development (2013) 1.83
Role of premature leptin surge in obesity resulting from intrauterine undernutrition. Cell Metab (2005) 1.83
T-type Ca2+ channels, SK2 channels and SERCAs gate sleep-related oscillations in thalamic dendrites. Nat Neurosci (2008) 1.79
Persistent expression of PDX-1 in the pancreas causes acinar-to-ductal metaplasia through Stat3 activation. Genes Dev (2006) 1.76