Published in Science on July 29, 2005
How reliable are empirical genomic scans for selective sweeps? Genome Res (2006) 4.14
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Genomewide spatial correspondence between nonsynonymous divergence and neutral polymorphism reveals extensive adaptation in Drosophila. Genetics (2007) 1.89
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Sequencing of pooled DNA samples (Pool-Seq) uncovers complex dynamics of transposable element insertions in Drosophila melanogaster. PLoS Genet (2012) 1.59
High rate of recent transposable element-induced adaptation in Drosophila melanogaster. PLoS Biol (2008) 1.52
A Polymorphism in the Processing Body Component Ge-1 Controls Resistance to a Naturally Occurring Rhabdovirus in Drosophila. PLoS Pathog (2016) 1.44
Field, genetic, and modeling approaches show strong positive selection acting upon an insecticide resistance mutation in Anopheles gambiae s.s. Mol Biol Evol (2010) 1.42
Evolution of hydra, a recently evolved testis-expressed gene with nine alternative first exons in Drosophila melanogaster. PLoS Genet (2007) 1.36
Successive increases in the resistance of Drosophila to viral infection through a transposon insertion followed by a Duplication. PLoS Genet (2011) 1.30
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The role of transposable elements in the evolution of non-mammalian vertebrates and invertebrates. Genome Biol (2010) 1.29
Genome-wide patterns of adaptation to temperate environments associated with transposable elements in Drosophila. PLoS Genet (2010) 1.24
Recent selective sweeps in North American Drosophila melanogaster show signatures of soft sweeps. PLoS Genet (2015) 1.18
Genome-wide association studies reveal a simple genetic basis of resistance to naturally coevolving viruses in Drosophila melanogaster. PLoS Genet (2012) 1.14
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Overexpression of the 14alpha-demethylase target gene (CYP51) mediates fungicide resistance in Blumeriella jaapii. Appl Environ Microbiol (2006) 1.13
Abundance and distribution of transposable elements in two Drosophila QTL mapping resources. Mol Biol Evol (2013) 1.12
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Population dynamics of PIWI-interacting RNAs (piRNAs) and their targets in Drosophila. Genome Res (2009) 1.10
Adaptation to diverse nitrogen-limited environments by deletion or extrachromosomal element formation of the GAP1 locus. Proc Natl Acad Sci U S A (2010) 1.10
Adaptive evolution involving gene duplication and insertion of a novel Ty1/copia-like retrotransposon in soybean. J Mol Evol (2009) 1.07
Nonadaptive explanations for signatures of partial selective sweeps in Drosophila. Mol Biol Evol (2008) 1.04
Heat-shock promoters: targets for evolution by P transposable elements in Drosophila. PLoS Genet (2006) 1.02
Population and sex differences in Drosophila melanogaster brain gene expression. BMC Genomics (2012) 1.01
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Insights from natural host-parasite interactions: the Drosophila model. Dev Comp Immunol (2013) 0.95
Vertically transmitted viral endosymbionts of insects: do sigma viruses walk alone? Proc Biol Sci (2012) 0.93
Transposable elements in natural populations of Drosophila melanogaster. Philos Trans R Soc Lond B Biol Sci (2010) 0.92
A recent adaptive transposable element insertion near highly conserved developmental loci in Drosophila melanogaster. Mol Biol Evol (2009) 0.92
Soft selective sweeps in complex demographic scenarios. Genetics (2014) 0.92
The contribution of transposable elements to expressed coding sequence in Arabidopsis thaliana. J Mol Evol (2009) 0.92
Evolutionary genomics of transposable elements in Saccharomyces cerevisiae. PLoS One (2012) 0.91
Remarkable site specificity of local transposition into the Hsp70 promoter of Drosophila melanogaster. Genetics (2006) 0.91
Being positive about selection. PLoS Biol (2006) 0.87
Drosophila americana as a model species for comparative studies on the molecular basis of phenotypic variation. Genome Biol Evol (2013) 0.87
The Role of piRNA-Mediated Epigenetic Silencing in the Population Dynamics of Transposable Elements in Drosophila melanogaster. PLoS Genet (2015) 0.86
Long-term and short-term evolutionary impacts of transposable elements on Drosophila. Genetics (2012) 0.85
Coexistence of trichome variation in a natural plant population: a combined study using ecological and candidate gene approaches. PLoS One (2011) 0.84
The standing pool of genomic structural variation in a natural population of Mimulus guttatus. Genome Biol Evol (2014) 0.84
Longevity GWAS Using the Drosophila Genetic Reference Panel. J Gerontol A Biol Sci Med Sci (2015) 0.84
Divergence of Drosophila melanogaster repeatomes in response to a sharp microclimate contrast in Evolution Canyon, Israel. Proc Natl Acad Sci U S A (2014) 0.83
A transposable element insertion confers xenobiotic resistance in Drosophila. PLoS Genet (2014) 0.83
Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data. G3 (Bethesda) (2015) 0.83
Population Structure Shapes Copy Number Variation in Malaria Parasites. Mol Biol Evol (2015) 0.82
Haplotype structure and expression divergence at the Drosophila cellular immune gene eater. Mol Biol Evol (2010) 0.82
Antagonistic changes in sensitivity to antifungal drugs by mutations of an important ABC transporter gene in a fungal pathogen. PLoS One (2010) 0.81
Adaptive divergence of a transcriptional enhancer between populations of Drosophila melanogaster. Philos Trans R Soc Lond B Biol Sci (2013) 0.81
Population- and sex-biased gene expression in the excretion organs of Drosophila melanogaster. G3 (Bethesda) (2014) 0.81
An age-of-allele test of neutrality for transposable element insertions. Genetics (2013) 0.80
Contrasting patterns of transposable element insertions in Drosophila heat-shock promoters. PLoS One (2009) 0.79
An adaptive allelic series featuring complex gene rearrangements. PLoS Genet (2011) 0.79
Association of hOGG1 Ser326Cys polymorphism with susceptibility to hepatocellular carcinoma. Int J Clin Exp Med (2015) 0.78
Enhancing the mathematical properties of new haplotype homozygosity statistics for the detection of selective sweeps. Theor Popul Biol (2015) 0.78
Transposable elements in cancer as a by-product of stress-induced evolvability. Front Genet (2014) 0.78
The genetics of host-virus coevolution in invertebrates. Curr Opin Virol (2014) 0.77
Elevated Linkage Disequilibrium and Signatures of Soft Sweeps Are Common in Drosophila melanogaster. Genetics (2016) 0.77
Lack of population differentiation patterns of previously identified putatively adaptive transposable element insertions at microgeographic scales. Biol Direct (2015) 0.77
Genomic and Transcriptomic Associations Identify a New Insecticide Resistance Phenotype for the Selective Sweep at the Cyp6g1 Locus of Drosophila melanogaster. G3 (Bethesda) (2016) 0.76
Survey of Global Genetic Diversity Within the Drosophila Immune System. Genetics (2016) 0.75
Parallel Evolution of Copy-Number Variation across Continents in Drosophila melanogaster. Mol Biol Evol (2016) 0.75
Reexamining the P-Element Invasion of Drosophila melanogaster Through the Lens of piRNA Silencing. Genetics (2016) 0.75
Adaptation of the osmotolerant yeast Zygosaccharomyces rouxii to an osmotic environment through copy number amplification of FLO11D. Genetics (2013) 0.75
Recurrent Gene Duplication Diversifies Genome Defense Repertoire in Drosophila. Mol Biol Evol (2016) 0.75
Genes belonging to the insulin and ecdysone signaling pathways can contribute to developmental time, lifespan and abdominal size variation in Drosophila americana. PLoS One (2014) 0.75
Natural selection in a population of Drosophila melanogaster explained by changes in gene expression caused by sequence variation in core promoter regions. BMC Evol Biol (2016) 0.75
Evolution. Rogue fruit fly DNA offers protection from insecticides. Science (2005) 0.75
Molecular Population Genetics. Genetics (2017) 0.75
The mechanism (Phe362Tyr mutation) behind resistance in Lepeophtheirus salmonis pre-dates organophosphate use in salmon farming. Sci Rep (2017) 0.75
Web-based, participant-driven studies yield novel genetic associations for common traits. PLoS Genet (2010) 5.02
High functional diversity in Mycobacterium tuberculosis driven by genetic drift and human demography. PLoS Biol (2008) 4.74
Pervasive hitchhiking at coding and regulatory sites in humans. PLoS Genet (2009) 4.02
Selection on codon bias. Annu Rev Genet (2008) 3.83
Pervasive natural selection in the Drosophila genome? PLoS Genet (2009) 3.27
Evidence that mutation is universally biased towards AT in bacteria. PLoS Genet (2010) 2.95
Evidence that adaptation in Drosophila is not limited by mutation at single sites. PLoS Genet (2010) 2.41
The large genome constraint hypothesis: evolution, ecology and phenotype. Ann Bot (2005) 2.33
Preferential duplication of conserved proteins in eukaryotic genomes. PLoS Biol (2004) 1.96
Genomewide spatial correspondence between nonsynonymous divergence and neutral polymorphism reveals extensive adaptation in Drosophila. Genetics (2007) 1.89
Drosophila melanogaster recombination rate calculator. Gene (2010) 1.78
Distinct changes of genomic biases in nucleotide substitution at the time of Mammalian radiation. Mol Biol Evol (2003) 1.72
General rules for optimal codon choice. PLoS Genet (2009) 1.71
Pervasive and persistent redundancy among duplicated genes in yeast. PLoS Genet (2008) 1.66
Efficient replication of over 180 genetic associations with self-reported medical data. PLoS One (2011) 1.65
Genomic heterogeneity of background substitutional patterns in Drosophila melanogaster. Genetics (2004) 1.61
Population genomics of rapid adaptation by soft selective sweeps. Trends Ecol Evol (2013) 1.60
Cryptic distant relatives are common in both isolated and cosmopolitan genetic samples. PLoS One (2012) 1.55
Genome patterns of selection and introgression of haplotypes in natural populations of the house mouse (Mus musculus). PLoS Genet (2012) 1.54
High rate of recent transposable element-induced adaptation in Drosophila melanogaster. PLoS Biol (2008) 1.52
Substantial regional variation in substitution rates in the human genome: importance of GC content, gene density, and telomere-specific effects. J Mol Evol (2005) 1.45
Reduced selection leads to accelerated gene loss in Shigella. Genome Biol (2007) 1.41
Relaxed purifying selection and possibly high rate of adaptation in primate lineage-specific genes. Genome Biol Evol (2010) 1.40
Do disparate mechanisms of duplication add similar genes to the genome? Trends Genet (2005) 1.39
Frequent adaptation and the McDonald-Kreitman test. Proc Natl Acad Sci U S A (2013) 1.37
Strong purifying selection at synonymous sites in D. melanogaster. PLoS Genet (2013) 1.34
Rates of DNA duplication and mitochondrial DNA insertion in the human genome. J Mol Evol (2003) 1.34
Heterozygote advantage as a natural consequence of adaptation in diploids. Proc Natl Acad Sci U S A (2011) 1.33
Host species and environmental effects on bacterial communities associated with Drosophila in the laboratory and in the natural environment. PLoS One (2013) 1.30
Protein evolution in the context of Drosophila development. J Mol Evol (2005) 1.29
X-linked genes evolve higher codon bias in Drosophila and Caenorhabditis. Genetics (2005) 1.26
Genome-wide patterns of adaptation to temperate environments associated with transposable elements in Drosophila. PLoS Genet (2010) 1.24
Empirical validation of pooled whole genome population re-sequencing in Drosophila melanogaster. PLoS One (2012) 1.16
Similar levels of X-linked and autosomal nucleotide variation in African and non-African populations of Drosophila melanogaster. BMC Evol Biol (2007) 1.15
The adaptive role of transposable elements in the Drosophila genome. Gene (2009) 1.14
Broker genes in human disease. Genome Biol Evol (2010) 1.13
Origins and rates of aneuploidy in human blastomeres. Fertil Steril (2011) 1.10
Codon bias and noncoding GC content correlate negatively with recombination rate on the Drosophila X chromosome. J Mol Evol (2005) 1.09
T-lex: a program for fast and accurate assessment of transposable element presence using next-generation sequencing data. Nucleic Acids Res (2010) 1.09
A spatially explicit nanomechanical model of the half-sarcomere: myofilament compliance affects Ca(2+)-activation. Ann Biomed Eng (2004) 1.08
Similarly strong purifying selection acts on human disease genes of all evolutionary ages. Genome Biol Evol (2009) 1.07
Nonadaptive explanations for signatures of partial selective sweeps in Drosophila. Mol Biol Evol (2008) 1.04
How intron splicing affects the deletion and insertion profile in Drosophila melanogaster. Genetics (2002) 1.03
Enhancer choice in cis and in trans in Drosophila melanogaster: role of the promoter. Genetics (2004) 1.03
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Evolutionary biology for the 21st century. PLoS Biol (2013) 1.01
Paucity of chimeric gene-transposable element transcripts in the Drosophila melanogaster genome. BMC Biol (2005) 1.00
Rapid sequence turnover at an intergenic locus in Drosophila. Mol Biol Evol (2004) 1.00
Population genomics of transposable elements in Drosophila. Annu Rev Genet (2014) 0.97
LDx: estimation of linkage disequilibrium from high-throughput pooled resequencing data. PLoS One (2012) 0.95
A novel method distinguishes between mutation rates and fixation biases in patterns of single-nucleotide substitution. J Mol Evol (2005) 0.93
Faster than neutral evolution of constrained sequences: the complex interplay of mutational biases and weak selection. Genome Biol Evol (2011) 0.93
Evolution of genome content: population dynamics of transposable elements in flies and humans. Methods Mol Biol (2012) 0.93
A recent adaptive transposable element insertion near highly conserved developmental loci in Drosophila melanogaster. Mol Biol Evol (2009) 0.92
Minor shift in background substitutional patterns in the Drosophila saltans and willistoni lineages is insufficient to explain GC content of coding sequences. BMC Biol (2006) 0.87
Inferring the strength of selection in Drosophila under complex demographic models. Mol Biol Evol (2008) 0.85
Molecular evolution of the testis TAFs of Drosophila. Mol Biol Evol (2009) 0.83
Genomic inference accurately predicts the timing and severity of a recent bottleneck in a nonmodel insect population. Mol Ecol (2013) 0.82
On the limitations of using ribosomal genes as references for the study of codon usage: a rebuttal. PLoS One (2012) 0.81
Correction: More effective drugs lead to harder selective sweeps in the evolution of drug resistance in HIV-1. Elife (2017) 0.75