Published in Proc Natl Acad Sci U S A on August 01, 2005
Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells. Proc Natl Acad Sci U S A (2007) 2.78
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Labeling live cells by copper-catalyzed alkyne--azide click chemistry. Bioconjug Chem (2010) 1.86
Quantitative biological imaging by ptychographic x-ray diffraction microscopy. Proc Natl Acad Sci U S A (2009) 1.78
A selective turn-on fluorescent sensor for imaging copper in living cells. J Am Chem Soc (2006) 1.72
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Molecular pathogenesis of Wilson and Menkes disease: correlation of mutations with molecular defects and disease phenotypes. J Med Genet (2007) 1.66
Fluxes in "free" and total zinc are essential for progression of intraerythrocytic stages of Plasmodium falciparum. Chem Biol (2012) 1.59
X-ray fluorescence microscopy reveals large-scale relocalization and extracellular translocation of cellular copper during angiogenesis. Proc Natl Acad Sci U S A (2007) 1.55
Calcium-dependent copper redistributions in neuronal cells revealed by a fluorescent copper sensor and X-ray fluorescence microscopy. Proc Natl Acad Sci U S A (2011) 1.40
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Highly sensitive and selective colorimetric sensors for uranyl (UO2(2+)): development and comparison of labeled and label-free DNAzyme-gold nanoparticle systems. J Am Chem Soc (2008) 1.28
Bio-metals imaging and speciation in cells using proton and synchrotron radiation X-ray microspectroscopy. J R Soc Interface (2009) 1.22
Labeling TiO2 nanoparticles with dyes for optical fluorescence microscopy and determination of TiO2-DNA nanoconjugate stability. Small (2009) 1.21
A targetable fluorescent sensor reveals that copper-deficient SCO1 and SCO2 patient cells prioritize mitochondrial copper homeostasis. J Am Chem Soc (2011) 1.16
Copper and angiogenesis: unravelling a relationship key to cancer progression. Clin Exp Pharmacol Physiol (2008) 1.15
Visualizing ascorbate-triggered release of labile copper within living cells using a ratiometric fluorescent sensor. J Am Chem Soc (2010) 1.13
Wilson disease at a single cell level: intracellular copper trafficking activates compartment-specific responses in hepatocytes. J Biol Chem (2010) 1.11
Visualizing metal ions in cells: an overview of analytical techniques, approaches, and probes. Biochim Biophys Acta (2012) 1.10
Differential tuning of the electron transfer parameters in 1,3,5-triarylpyrazolines: a rational design approach for optimizing the contrast ratio of fluorescent probes. J Am Chem Soc (2008) 1.08
Electronically tuned 1,3,5-triarylpyrazolines as Cu(I)-selective fluorescent probes. Org Biomol Chem (2009) 1.03
Kinetically controlled photoinduced electron transfer switching in Cu(I)-responsive fluorescent probes. J Am Chem Soc (2010) 0.99
Designed to dissolve: suppression of colloidal aggregation of Cu(I)-selective fluorescent probes in aqueous buffer and in-gel detection of a metallochaperone. J Am Chem Soc (2011) 0.97
Near-infrared fluorescent sensor for in vivo copper imaging in a murine Wilson disease model. Proc Natl Acad Sci U S A (2012) 0.97
Copper redistribution in Atox1-deficient mouse fibroblast cells. J Biol Inorg Chem (2009) 0.97
Synthetic fluorescent probes for studying copper in biological systems. Chem Soc Rev (2015) 0.96
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Sensing metal ions with DNA building blocks: fluorescent pyridobenzimidazole nucleosides. J Am Chem Soc (2006) 0.93
The interaction of biological and noxious transition metals with the zinc probes FluoZin-3 and Newport Green. Anal Biochem (2008) 0.93
Elemental and chemically specific X-ray fluorescence imaging of biological systems. Chem Rev (2014) 0.93
Metal acquisition and availability in the mitochondria. Chem Rev (2009) 0.93
Synchrotron X-ray imaging reveals a correlation of tumor copper speciation with Clioquinol's anticancer activity. J Cell Biochem (2009) 0.92
Predicting the photoinduced electron transfer thermodynamics in polyfluorinated 1,3,5-triarylpyrazolines based on multiple linear free energy relationships. Org Biomol Chem (2009) 0.92
High-contrast Cu(I)-selective fluorescent probes based on synergistic electronic and conformational switching. Chem Sci (2011) 0.91
Probing oxidative stress: Small molecule fluorescent sensors of metal ions, reactive oxygen species, and thiols. Coord Chem Rev (2012) 0.90
Experimental demonstration of novel imaging geometries for x-ray fluorescence computed tomography. Med Phys (2013) 0.90
Recognition- and reactivity-based fluorescent probes for studying transition metal signaling in living systems. Acc Chem Res (2015) 0.89
Synthetic fluorescent probes for monovalent copper. Curr Opin Chem Biol (2013) 0.88
Effect of cerebral amyloid angiopathy on brain iron, copper, and zinc in Alzheimer's disease. J Alzheimers Dis (2011) 0.87
Opportunities in multidimensional trace metal imaging: taking copper-associated disease research to the next level. Anal Bioanal Chem (2012) 0.87
Human macrophage ATP7A is localized in the trans-Golgi apparatus, controls intracellular copper levels, and mediates macrophage responses to dermal wounds. Inflammation (2012) 0.86
Radioactivity-synchronized fluorescence enhancement using a radionuclide fluorescence-quenched dye. J Am Chem Soc (2009) 0.86
Copper import into the mitochondrial matrix in Saccharomyces cerevisiae is mediated by Pic2, a mitochondrial carrier family protein. J Biol Chem (2013) 0.85
Plutonium uptake and distribution in mammalian cells: molecular vs. polymeric plutonium. Int J Radiat Biol (2011) 0.85
A cell-permeable gadolinium contrast agent for magnetic resonance imaging of copper in a Menkes disease model. Chem Sci (2012) 0.84
DNA as sensors and imaging agents for metal ions. Inorg Chem (2013) 0.84
High-contrast fluorescence sensing of aqueous Cu(I) with triarylpyrazoline probes: dissecting the roles of ligand donor strength and excited state proton transfer. Dalton Trans (2012) 0.84
Assembling the pieces. Nat Chem Biol (2008) 0.83
Age-related cellular copper dynamics in the fungal ageing model Podospora anserina and in ageing human fibroblasts. PLoS One (2009) 0.83
Demand for Zn2+ in acid-secreting gastric mucosa and its requirement for intracellular Ca2+. PLoS One (2011) 0.82
Copper-triggered aggregation of ubiquitin. PLoS One (2009) 0.82
Synchrotron radiation induced X-ray emission studies of the antioxidant mechanism of the organoselenium drug ebselen. J Biol Inorg Chem (2012) 0.82
Subcellular redistribution and mitotic inheritance of transition metals in proliferating mouse fibroblast cells. Metallomics (2013) 0.82
Loss of pluripotency in human embryonic stem cells directly correlates with an increase in nuclear zinc. PLoS One (2010) 0.81
Detection of genetically altered copper levels in Drosophila tissues by synchrotron x-ray fluorescence microscopy. PLoS One (2011) 0.80
Fluorescence lifetime imaging of physiological free Cu(II) levels in live cells with a Cu(II)-selective carbonic anhydrase-based biosensor. Metallomics (2014) 0.79
Structure and dynamics of metalloproteins in live cells. Methods Cell Biol (2008) 0.79
Toward the detection of cellular copper(II) by a light-activated fluorescence increase. Inorg Chem (2010) 0.78
DNAzyme catalytic beacon sensors that resist temperature-dependent variations. Chem Commun (Camb) (2009) 0.78
Labile Low-Molecular-Mass Metal Complexes in Mitochondria: Trials and Tribulations of a Burgeoning Field. Biochemistry (2016) 0.77
X-ray fluorescence microscopy for investigation of archival tissues. Health Phys (2012) 0.77
Probing ternary complex equilibria of crown ether ligands by time-resolved fluorescence spectroscopy. J Phys Chem B (2014) 0.77
Detection of Labile Low-Molecular-Mass Transition Metal Complexes in Mitochondria. Biochemistry (2015) 0.77
Nanodiamonds act as Trojan horse for intracellular delivery of metal ions to trigger cytotoxicity. Part Fibre Toxicol (2015) 0.77
Sequence-specific DNA cleavage mediated by bipyridine polyamide conjugates. Nucleic Acids Res (2008) 0.77
Overlap of copper and iron uptake systems in mitochondria in Saccharomyces cerevisiae. Open Biol (2016) 0.77
Preparing adherent cells for X-ray fluorescence imaging by chemical fixation. J Vis Exp (2015) 0.76
Imaging trace element distributions in single organelles and subcellular features. Sci Rep (2016) 0.76
Bioavailability of metal ions and evolutionary adaptation. Life (Basel) (2012) 0.76
Preserving elemental content in adherent mammalian cells for analysis by synchrotron-based x-ray fluorescence microscopy. J Microsc (2016) 0.75
A benzothiazole alkyne fluorescent sensor for Cu detection in living cell. Bioorg Med Chem Lett (2012) 0.75
Development of a single-cell X-ray fluorescence flow cytometer. J Synchrotron Radiat (2016) 0.75
The effect of metalloprotein inhibitors on cellular metal ion content and distribution. Metallomics (2017) 0.75
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Organelle pH studies using targeted avidin and fluorescein-biotin. Chem Biol (2000) 1.64
Quantifying trace elements in individual aquatic protist cells with a synchrotron X-ray fluorescence microprobe. Anal Chem (2003) 1.64
The role of copper in neurodegenerative disease. Neurobiol Dis (1999) 1.63
Essential role for Atox1 in the copper-mediated intracellular trafficking of the Menkes ATPase. Proc Natl Acad Sci U S A (2003) 1.62
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Illuminating zinc in biological systems. Chemistry (2004) 1.29
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Copper chaperones: personal escorts for metal ions. J Bioenerg Biomembr (2002) 1.19
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A general strategy to convert the MerR family proteins into highly sensitive and selective fluorescent biosensors for metal ions. J Am Chem Soc (2004) 1.16
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Complex formation constants for the aqueous copper(I)-acetonitrile system by a simple general method. Inorg Chem (2001) 0.90
Protein oxidation implicated as the primary determinant of bacterial radioresistance. PLoS Biol (2007) 3.22
c-Type cytochrome-dependent formation of U(IV) nanoparticles by Shewanella oneidensis. PLoS Biol (2006) 2.80
Neural circuits underlying imitation learning of hand actions: an event-related fMRI study. Neuron (2004) 2.73
Biology of TiO2-oligonucleotide nanocomposites. Nat Mater (2003) 2.68
A fluorogenic probe for the copper(I)-catalyzed azide-alkyne ligation reaction: modulation of the fluorescence emission via 3(n,pi)-1(pi,pi) inversion. J Am Chem Soc (2004) 2.37
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Ductal carcinoma in situ: X-ray fluorescence microscopy and dynamic contrast-enhanced MR imaging reveals gadolinium uptake within neoplastic mammary ducts in a murine model. Radiology (2009) 2.02
Mechanisms of gold biomineralization in the bacterium Cupriavidus metallidurans. Proc Natl Acad Sci U S A (2009) 1.81
Zinc availability regulates exit from meiosis in maturing mammalian oocytes. Nat Chem Biol (2010) 1.76
Quantifying trace elements in individual aquatic protist cells with a synchrotron X-ray fluorescence microprobe. Anal Chem (2003) 1.64
High resolution 3D x-ray diffraction microscopy. Phys Rev Lett (2002) 1.63
Zinc concentration in esophageal biopsy specimens measured by x-ray fluorescence and esophageal cancer risk. J Natl Cancer Inst (2005) 1.63
Elemental and redox analysis of single bacterial cells by x-ray microbeam analysis. Science (2004) 1.62
X-ray fluorescence microscopy reveals large-scale relocalization and extracellular translocation of cellular copper during angiogenesis. Proc Natl Acad Sci U S A (2007) 1.55
Imaging metals in proteins by combining electrophoresis with rapid x-ray fluorescence mapping. ACS Chem Biol (2010) 1.55
Migration of mercury from dental amalgam through human teeth. J Synchrotron Radiat (2008) 1.53
Deinococcus geothermalis: the pool of extreme radiation resistance genes shrinks. PLoS One (2007) 1.52
Intracellular distribution of TiO2-DNA oligonucleotide nanoconjugates directed to nucleolus and mitochondria indicates sequence specificity. Nano Lett (2007) 1.43
Radiation damage in protein crystals is reduced with a micron-sized X-ray beam. Proc Natl Acad Sci U S A (2011) 1.42
Calcium-dependent copper redistributions in neuronal cells revealed by a fluorescent copper sensor and X-ray fluorescence microscopy. Proc Natl Acad Sci U S A (2011) 1.40
Zinc sparks are triggered by fertilization and facilitate cell cycle resumption in mammalian eggs. ACS Chem Biol (2011) 1.37
Nanoparticles for applications in cellular imaging. Nanoscale Res Lett (2007) 1.34
Hard X-ray fluorescence tomography--an emerging tool for structural visualization. Curr Opin Struct Biol (2010) 1.32
Quantitative 3D elemental microtomography of Cyclotella meneghiniana at 400-nm resolution. Proc Natl Acad Sci U S A (2010) 1.32
The cellular distribution and oxidation state of platinum(II) and platinum(IV) antitumour complexes in cancer cells. J Biol Inorg Chem (2003) 1.25
Synthesis, characterization, and in vitro testing of superparamagnetic iron oxide nanoparticles targeted using folic Acid-conjugated dendrimers. ACS Nano (2008) 1.22
Labeling TiO2 nanoparticles with dyes for optical fluorescence microscopy and determination of TiO2-DNA nanoconjugate stability. Small (2009) 1.21
DNA-TiO2 nanoconjugates labeled with magnetic resonance contrast agents. J Am Chem Soc (2007) 1.19
A high-performance nanobio photocatalyst for targeted brain cancer therapy. Nano Lett (2009) 1.19
Melanosomal sequestration of cytotoxic drugs contributes to the intractability of malignant melanomas. Proc Natl Acad Sci U S A (2006) 1.18
Changes of the phagosomal elemental concentrations by Mycobacterium tuberculosis Mramp. Microbiology (2005) 1.17
Copper and angiogenesis: unravelling a relationship key to cancer progression. Clin Exp Pharmacol Physiol (2008) 1.15
Unexpected role of the copper transporter ATP7A in PDGF-induced vascular smooth muscle cell migration. Circ Res (2010) 1.12
Zinc(II)-selective ratiometric fluorescent sensors based on inhibition of excited-state intramolecular proton transfer. Chemistry (2004) 1.12
Quantitative X-ray imaging of intraplaque hemorrhage in aortas of apoE(-/-)/LDL(-/-) double knockout mice. Invest Radiol (2007) 1.11
Selective sequestration of strontium in desmid green algae by biogenic co-precipitation with barite. ChemSusChem (2011) 1.11
Trace metal imaging with high spatial resolution: applications in biomedicine. Metallomics (2010) 1.11
Wilson disease at a single cell level: intracellular copper trafficking activates compartment-specific responses in hepatocytes. J Biol Chem (2010) 1.11
Nanocarriers enhance Doxorubicin uptake in drug-resistant ovarian cancer cells. Cancer Res (2011) 1.09
X-ray fluorescence microscopy reveals accumulation and secretion of discrete intracellular zinc pools in the lactating mouse mammary gland. PLoS One (2010) 1.09
Differential tuning of the electron transfer parameters in 1,3,5-triarylpyrazolines: a rational design approach for optimizing the contrast ratio of fluorescent probes. J Am Chem Soc (2008) 1.08
Uptake and distribution of ultrasmall anatase TiO2 Alizarin red S nanoconjugates in Arabidopsis thaliana. Nano Lett (2010) 1.08
Epidermal growth factor receptor targeted nuclear delivery and high-resolution whole cell X-ray imaging of Fe3O4@TiO2 nanoparticles in cancer cells. ACS Nano (2013) 1.07
Multiple protective activities of neuroglobin in cultured neuronal cells exposed to hypoxia re-oxygenation injury. J Neurochem (2009) 1.06
Quantification of phosphorus in single cells using synchrotron X-ray fluorescence. J Synchrotron Radiat (2010) 1.04
Past and future work on radiobiology mega-studies: a case study at Argonne National Laboratory. Health Phys (2011) 1.04
Quantitative imaging of cell-permeable magnetic resonance contrast agents using x-ray fluorescence. Mol Imaging (2006) 1.04
Electronically tuned 1,3,5-triarylpyrazolines as Cu(I)-selective fluorescent probes. Org Biomol Chem (2009) 1.03
Hard X-ray microprobe studies of chromium(VI)-treated V79 Chinese hamster lung cells: intracellular mapping of the biotransformation products of a chromium carcinogen. J Biol Inorg Chem (2002) 1.00
A method for phase reconstruction from measurements obtained using a configured detector with a scanning transmission X-ray microscope. Nucl Instrum Methods Phys Res A (2007) 1.00
The role of CAX1 and CAX3 in elemental distribution and abundance in Arabidopsis seed. Plant Physiol (2011) 0.99
Kinetically controlled photoinduced electron transfer switching in Cu(I)-responsive fluorescent probes. J Am Chem Soc (2010) 0.99
Gadolinium-conjugated TiO2-DNA oligonucleotide nanoconjugates show prolonged intracellular retention period and T1-weighted contrast enhancement in magnetic resonance images. Nanomedicine (2008) 0.99
Quantitative comparison of preparation methodologies for X-ray fluorescence microscopy of brain tissue. Anal Bioanal Chem (2011) 0.99
Metal exposure and Alzheimer's pathogenesis. J Struct Biol (2006) 0.98
The unique biogeochemical signature of the marine diazotroph trichodesmium. Front Microbiol (2012) 0.98
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A fluorogenic probe for the catalyst-free detection of azide-tagged molecules. J Am Chem Soc (2012) 0.98
Designed to dissolve: suppression of colloidal aggregation of Cu(I)-selective fluorescent probes in aqueous buffer and in-gel detection of a metallochaperone. J Am Chem Soc (2011) 0.97
Increased brain iron coincides with early plaque formation in a mouse model of Alzheimer's disease. Neuroimage (2010) 0.97
X-ray fluorescence microscopy reveals the role of selenium in spermatogenesis. J Mol Biol (2009) 0.97
The direct mapping of the uptake of platinum anticancer agents in individual human ovarian adenocarcinoma cells using a hard X-ray microprobe. Cancer Res (2003) 0.97
Copper redistribution in Atox1-deficient mouse fibroblast cells. J Biol Inorg Chem (2009) 0.97
Role of copper transport protein antioxidant 1 in angiotensin II-induced hypertension: a key regulator of extracellular superoxide dismutase. Hypertension (2012) 0.96
Biological applications of X-ray microprobes. Int J Radiat Biol (2009) 0.95
Observation of an x-ray vortex. Opt Lett (2002) 0.94
The fate of platinum(II) and platinum(IV) anti-cancer agents in cancer cells and tumours. J Struct Biol (2006) 0.94
Cell-permeable MR contrast agents with increased intracellular retention. Bioconjug Chem (2008) 0.94
Correlative microXRF and optical immunofluorescence microscopy of adherent cells labeled with ultrasmall gold particles. J Struct Biol (2006) 0.94
Signal Discrimination Between Fluorescent Proteins in Live Cells by Long-wavelength Optical Modulation. J Phys Chem Lett (2012) 0.94
Iron accumulates in Huntington's disease neurons: protection by deferoxamine. PLoS One (2013) 0.93
Silicon nitride as a versatile growth substrate for microspectroscopic imaging and mapping of individual cells. Mol Biosyst (2010) 0.93
Effect of manual lymph drainage on the course of serum levels of muscle enzymes after treadmill exercise. Am J Phys Med Rehabil (2006) 0.92
Predicting the photoinduced electron transfer thermodynamics in polyfluorinated 1,3,5-triarylpyrazolines based on multiple linear free energy relationships. Org Biomol Chem (2009) 0.92
Levels of zinc, selenium, calcium, and iron in benign breast tissue and risk of subsequent breast cancer. Cancer Epidemiol Biomarkers Prev (2007) 0.92
Design of emission ratiometric metal-ion sensors with enhanced two-photon cross section and brightness. J Am Chem Soc (2007) 0.91
High-resolution X-ray imaging of Plasmodium falciparum-infected red blood cells. Cytometry A (2008) 0.91
Reduced utilization of selenium by naked mole rats due to a specific defect in GPx1 expression. J Biol Chem (2011) 0.91