Published in JAMA on August 10, 2005
Managing incidental findings in human subjects research: analysis and recommendations. J Law Med Ethics (2008) 12.10
Managing incidental findings and research results in genomic research involving biobanks and archived data sets. Genet Med (2012) 9.65
Public expectations for return of results from large-cohort genetic research. Am J Bioeth (2008) 7.63
Ethical and practical guidelines for reporting genetic research results to study participants: updated guidelines from a National Heart, Lung, and Blood Institute working group. Circ Cardiovasc Genet (2010) 6.74
Compliance with results reporting at ClinicalTrials.gov. N Engl J Med (2015) 4.17
Ethics. Incidental findings in brain imaging research. Science (2006) 3.10
Communicating the results of clinical research to participants: attitudes, practices, and future directions. PLoS Med (2008) 3.05
Implications of disclosing individual results of clinical research. JAMA (2006) 2.75
Understanding incidental findings in the context of genetics and genomics. J Law Med Ethics (2008) 2.50
Public preferences regarding the return of individual genetic research results: findings from a qualitative focus group study. Genet Med (2012) 2.39
Practical implementation issues and challenges for biobanks in the return of individual research results. Genet Med (2012) 2.32
Providing research results to participants: attitudes and needs of adolescents and parents of children with cancer. J Clin Oncol (2009) 2.28
Incidental findings in human subjects research: what do investigators owe research participants? J Law Med Ethics (2008) 2.28
The legal risks of returning results of genomics research. Genet Med (2012) 2.15
Incidental findings in genetics research using archived DNA. J Law Med Ethics (2008) 2.03
Genomic research and incidental findings. J Law Med Ethics (2008) 2.02
Informed consent in genomics and genetic research. Annu Rev Genomics Hum Genet (2010) 1.98
The law of incidental findings in human subjects research: establishing researchers' duties. J Law Med Ethics (2008) 1.84
Toxic ignorance and right-to-know in biomonitoring results communication: a survey of scientists and study participants. Environ Health (2009) 1.74
Communicating results in post-Belmont era biomonitoring studies: lessons from genetics and neuroimaging research. Environ Res (2014) 1.68
Considerations for designing a prototype genetic test for use in translational research. Public Health Genomics (2009) 1.67
Prospective biorepository participants' perspectives on access to research results. J Empir Res Hum Res Ethics (2009) 1.67
Changing perspectives in biobank research: from individual rights to concerns about public health regarding the return of results. Eur J Hum Genet (2009) 1.64
Using AD biomarker research results for clinical care: a survey of ADNI investigators. Neurology (2013) 1.63
Researcher perspectives on disclosure of incidental findings in genetic research. J Empir Res Hum Res Ethics (2010) 1.55
Offering results to research participants. BMJ (2006) 1.54
Taking aims seriously: repository research and limits on the duty to return individual research findings. Genet Med (2012) 1.49
Confronting real time ethical, legal, and social issues in the Electronic Medical Records and Genomics (eMERGE) Consortium. Genet Med (2010) 1.47
IRB perspectives on the return of individual results from genomic research. Genet Med (2012) 1.47
Public perspectives on returning genetics and genomics research results. Public Health Genomics (2011) 1.42
Disclosing individual CDKN2A research results to melanoma survivors: interest, impact, and demands on researchers. Cancer Epidemiol Biomarkers Prev (2011) 1.32
Ethical challenges in genotype-driven research recruitment. Genome Res (2010) 1.26
What is a meaningful result? Disclosing the results of genomic research in autism to research participants. Eur J Hum Genet (2010) 1.26
Institutional review board challenges related to community-based participatory research on human exposure to environmental toxins: a case study. Environ Health (2010) 1.23
Returning individual research results: development of a cancer genetics education and risk communication protocol. J Empir Res Hum Res Ethics (2010) 1.22
Testing for sexually transmitted infections in a population-based sexual health survey: development of an acceptable ethical approach. J Med Ethics (2012) 1.21
Incidental findings found in "healthy" volunteers during imaging performed for research: current legal and ethical implications. Br J Radiol (2010) 1.18
Genetics specialists' perspectives on disclosure of genomic incidental findings in the clinical setting. Patient Educ Couns (2012) 1.17
Return of results: ethical and legal distinctions between research and clinical care. Am J Med Genet C Semin Med Genet (2014) 1.16
Incidental findings in pediatric research. J Law Med Ethics (2008) 1.15
Participant experiences in a breastmilk biomonitoring study: a qualitative assessment. Environ Health (2009) 1.14
When research seems like clinical care: a qualitative study of the communication of individual cancer genetic research results. BMC Med Ethics (2008) 1.13
Ethical, legal, and social considerations in conducting the Human Microbiome Project. Genome Res (2008) 1.10
Returning genetic research results: study type matters. Per Med (2013) 1.09
Detecting awareness after severe brain injury. Nat Rev Neurosci (2013) 1.09
Researcher practices on returning genetic research results. Genet Test Mol Biomarkers (2010) 1.08
A framework for analyzing the ethics of disclosing genetic research findings. J Law Med Ethics (2014) 1.04
Preferences regarding genetic research results: comparing veterans and nonveterans responses. Public Health Genomics (2010) 1.03
Offering results to research participants. BMJ (2006) 1.01
Not so simple: a quasi-experimental study of how researchers adjudicate genetic research results. Eur J Hum Genet (2011) 1.00
Genetic susceptibility testing for neurodegenerative diseases: ethical and practice issues. Prog Neurobiol (2013) 0.98
Environmental health research on hazards in the home and the duty to warn. Bioethics (2008) 0.96
Issues and challenges of involving users in medical device development. Health Expect (2008) 0.95
Individual genetic and genomic research results and the tradition of informed consent: exploring US review board guidance. J Med Ethics (2012) 0.95
Approaches to informed consent for hypothesis-testing and hypothesis-generating clinical genomics research. BMC Med Genomics (2012) 0.93
Community-based participatory research (CBPR) approach to study children's health in China: experiences and reflections. Int J Nurs Stud (2011) 0.92
Attitudes of Canadian researchers toward the return to participants of incidental and targeted genomic findings obtained in a pediatric research setting. Genet Med (2013) 0.91
IRB chairs' perspectives on genotype-driven research recruitment. IRB (2012) 0.91
One thing leads to another: the cascade of obligations when researchers report genetic research results to study participants. Eur J Hum Genet (2012) 0.90
The Legal Implications of Report Back in Household Exposure Studies. Environ Health Perspect (2016) 0.90
Funding considerations for the disclosure of genetic incidental findings in biobank research. Clin Genet (2013) 0.87
The current impact of incidental findings found during neuroimaging on neurologists' workloads. PLoS One (2015) 0.86
Should we disclose amyloid imaging results to cognitively normal individuals? Neurodegener Dis Manag (2013) 0.86
Participants' experiences of being debriefed to placebo allocation in a clinical trial. Qual Health Res (2012) 0.85
Amyloid imaging, risk disclosure and Alzheimer's disease: ethical and practical issues. Neurodegener Dis Manag (2015) 0.84
Genomic sequencing in clinical trials. J Transl Med (2011) 0.83
Opinions and intentions of parents of an autistic child toward genetic research results: two typical profiles. Eur J Hum Genet (2011) 0.83
Recommendations for the return of research results to study participants and guardians: a report from the Children's Oncology Group. J Clin Oncol (2012) 0.83
Participant use and communication of findings from exome sequencing: a mixed-methods study. Genet Med (2015) 0.82
Reporting actionable research results: shared secrets can save lives. Sci Transl Med (2012) 0.81
Subjects' views of obligations to ensure post-trial access to drugs, care and information: qualitative results from the Experiences of Participants in Clinical Trials (EPIC) study. J Med Ethics (2009) 0.80
Recommendations for ethical approaches to genotype-driven research recruitment. Hum Genet (2012) 0.80
Initial experience with a group presentation of study results to research participants. Trials (2008) 0.79
Acknowledging awareness: informing families of individual research results for patients in the vegetative state. J Med Ethics (2014) 0.79
Trials and tribulations of protecting children from environmental hazards. Environ Health Perspect (2006) 0.78
Patient involvement in clinical research: why, when, and how. Patient Prefer Adherence (2016) 0.77
Genotype-driven recruitment: a strategy whose time has come? BMC Med Genomics (2013) 0.77
Reciprocity-based reasons for benefiting research participants: most fail, the most plausible is problematic. Bioethics (2013) 0.75
Disclosure of individualized research results: a precautionary approach. Account Res (2011) 0.75
Post-genomic clinical trials: the perspective of ACGT. Ecancermedicalscience (2008) 0.75
Automatic Placement of Genomic Research Results in Medical Records: Do Researchers Have a Duty? Should Participants Have a Choice? J Law Med Ethics (2015) 0.75
Lay Attitudes Toward Trust, Uncertainty, and the Return of Pediatric Research Results in Biobanking. AJOB Empir Bioeth (2015) 0.75
A Systematic Review of the Management of Incidental Findings in Genomic Research. BEOnline (2016) 0.75
Guidelines for genetic testing of healthy children - addendum: A joint statement with the Canadian College of Medical Geneticists. Paediatr Child Health (2008) 0.75
Teaching health law. J Law Med Ethics (2012) 0.75
Ethical issues in diagnosing and treating Alzheimer disease. Psychiatry (Edgmont) (2006) 0.75
Return of individual genomic research results: what do consent forms tell participants? Eur J Hum Genet (2016) 0.75
Views of Cohort Study Participants about Returning Research Results in the Context of Precision Medicine. Public Health Genomics (2016) 0.75
Changing the conversation about brain death. Am J Bioeth (2014) 8.71
A plea for pragmatism in clinical research ethics. Am J Bioeth (2008) 6.91
A critique of clinical equipoise. Therapeutic misconception in the ethics of clinical trials. Hastings Cent Rep (2003) 6.00
Bench to bedside: mapping the moral terrain of clinical research. Hastings Cent Rep (2008) 4.98
Money and distorted ethical judgments about research: ethical assessment of the TeGenero TGN1412 trial. Am J Bioeth (2007) 4.81
Clinical trials and medical care: defining the therapeutic misconception. PLoS Med (2007) 3.77
What makes killing wrong? J Med Ethics (2012) 3.74
Communicating the results of clinical research to participants: attitudes, practices, and future directions. PLoS Med (2008) 3.05
Placebos without deception: a randomized controlled trial in irritable bowel syndrome. PLoS One (2010) 3.03
Informed consent for pragmatic trials--the integrated consent model. N Engl J Med (2014) 3.01
Prescribing "placebo treatments": results of national survey of US internists and rheumatologists. BMJ (2008) 2.84
Rethinking risk-benefit assessment for phase I cancer trials. J Clin Oncol (2006) 2.73
Medicare's requirement for research participation as a condition of coverage: is it ethical? JAMA (2006) 2.43
Research with stored biological samples: what do research participants want? Arch Intern Med (2005) 2.43
Can research and care be ethically integrated? Hastings Cent Rep (2011) 2.15
Going off-label without venturing off-course: evidence and ethical off-label prescribing. Arch Intern Med (2009) 2.12
Deception in the pursuit of science. Arch Intern Med (2004) 1.99
Is placebo surgery unethical? N Engl J Med (2002) 1.94
Ethical issues in community-based participatory research: balancing rigorous research with community participation in community intervention studies. Prog Community Health Partnersh (2007) 1.90
Viewpoint: what is the best and most ethical model for the relationship between mainstream and alternative medicine: opposition, integration, or pluralism? Acad Med (2005) 1.79
Clinical pragmatism: a method of moral problem solving. Kennedy Inst Ethics J (1997) 1.74
Control group selection in critical care randomized controlled trials evaluating interventional strategies: An ethical assessment. Crit Care Med (2004) 1.71
The nocebo effect and its relevance for clinical practice. Psychosom Med (2011) 1.69
Is emergency research without initial consent justified?: the consent substitute model. Arch Intern Med (2010) 1.65
A normative justification for distinguishing the ethics of clinical research from the ethics of medical care. J Law Med Ethics (2005) 1.47
Misunderstanding, period. IRB (2011) 1.40
Clinical research and the physician-patient relationship. Ann Intern Med (2003) 1.39
Defining death: the importance of scientific candor and transparency. Intensive Care Med (2014) 1.38
Enrolling the uninsured in clinical trials: an ethical perspective. Crit Care Med (2003) 1.37
National Depressive and Manic-Depressive Association consensus statement on the use of placebo in clinical trials of mood disorders. Arch Gen Psychiatry (2002) 1.29
Money, coercion, and undue inducement: attitudes about payments to research participants. IRB (2012) 1.29
Placebo Effects in Medicine. N Engl J Med (2015) 1.29
The clinician-investigator: unavoidable but manageable tension. Kennedy Inst Ethics J (2003) 1.28
The dead donor rule and organ transplantation. N Engl J Med (2008) 1.28
Pragmatic Randomized Trials Without Standard Informed Consent?: A National Survey. Ann Intern Med (2015) 1.20
The randomized controlled trial as a demonstration project: an ethical perspective. Am J Psychiatry (2009) 1.15
How placebo responses are formed: a learning perspective. Philos Trans R Soc Lond B Biol Sci (2011) 1.15
Placebo effect studies are susceptible to response bias and to other types of biases. J Clin Epidemiol (2011) 1.13
Performing nondiagnostic research biopsies in irradiated tissue: a review of scientific, clinical, and ethical considerations. J Clin Oncol (2008) 1.12
Harnessing the placebo effect: the need for translational research. Philos Trans R Soc Lond B Biol Sci (2011) 1.11
Patients' attitudes about the use of placebo treatments: telephone survey. BMJ (2013) 1.10
Ethical framework for the use of sham procedures in clinical trials. Crit Care Med (2003) 1.08
Role of expectations in health. Curr Opin Psychiatry (2011) 1.08
Alternative medicine research in clinical practice: a US national survey. Arch Intern Med (2009) 1.07
The dead-donor rule and the future of organ donation. N Engl J Med (2013) 1.05
Justice and fairness in the Kennedy Krieger Institute lead paint study: the ethics of public health research on less expensive, less effective interventions. Am J Public Health (2006) 1.04
Screening and cognitive impairment: ethics of forgoing mammography in older women. J Am Geriatr Soc (2004) 1.00
Lessons from recent research about the placebo effect--from art to science. JAMA (2011) 1.00
Enrolling decisionally impaired adults in clinical research. Med Care (2002) 1.00
Misconceptions about coercion and undue influence: reflections on the views of IRB members. Bioethics (2012) 1.00
The placebo phenomenon: implications for the ethics of shared decision-making. J Gen Intern Med (2012) 0.98
Ethical aspects of research into the etiology of autism. Ment Retard Dev Disabil Res Rev (2003) 0.97
Clinical pragmatism: bridging theory and practice. Kennedy Inst Ethics J (1998) 0.96
Principles of early stopping of randomized trials for efficacy: a critique of equipoise and an alternative nonexploitation ethical framework. Kennedy Inst Ethics J (2005) 0.94
Clinical research before informed consent. Kennedy Inst Ethics J (2014) 0.94
Self-reported practices and attitudes of US oncologists regarding off-protocol therapy. J Clin Oncol (2008) 0.93
Evidence-based medicine: watching out for its friends. Perspect Biol Med (2005) 0.91
What counts as reliable evidence for public health policy: the case of circumcision for preventing HIV infection. BMC Med Res Methodol (2011) 0.90
The research-clinical practice distinction, learning health systems, and relationships. Hastings Cent Rep (2013) 0.89
Equipoise: asking the right questions for clinical trial design. Nat Rev Clin Oncol (2012) 0.89
Simulated patient studies: an ethical analysis. Milbank Q (2012) 0.89
Research ethics and misguided moral intuition. J Law Med Ethics (2004) 0.89
Twenty-five years of therapeutic misconception. Hastings Cent Rep (2008) 0.86
The potential benefit of the placebo effect in sham-controlled trials: implications for risk-benefit assessments and informed consent. J Med Ethics (2012) 0.86
Vertebroplasty and the placebo response. Radiology (2011) 0.86
Ethical significance of ethics-related empirical research. J Natl Cancer Inst (2002) 0.85
Responding to medical pluralism in practice: a principled ethical approach. J Am Board Fam Med (2007) 0.85
What physician-investigators owe patients who participate in research. JAMA (2010) 0.84
Can we handle the truth? Legal fictions in the determination of death. Am J Law Med (2010) 0.84
The surgical intensivist as mediator of end-of-life issues in the care of critically ill patients. J Am Coll Surg (2003) 0.83
When scientists deceive: applying the federal regulations. J Law Med Ethics (2009) 0.83
A prescription for ethical learning. Commentary. Hastings Cent Rep (2013) 0.83
Waivers and Alterations to Consent in Pragmatic Clinical Trials: Respecting the Principle of Respect for Persons. IRB (2016) 0.83
Does the evidence make a difference in consumer behavior? Sales of supplements before and after publication of negative research results. J Gen Intern Med (2008) 0.82
A planned death in the family. Hastings Cent Rep (2009) 0.81
Placebo-controlled procedural trials for neurological conditions. Neurotherapeutics (2007) 0.80
Ethical considerations in psychopharmacological research involving decisionally impaired subjects. Psychopharmacology (Berl) (2003) 0.80
Acupuncture for chronic low back pain. N Engl J Med (2010) 0.80
Religion, clinicians, and the integration of complementary and alternative medicines. J Altern Complement Med (2009) 0.79
Can coverage be rescinded when negative trial results threaten a popular procedure? The ongoing saga of vertebroplasty. Health Aff (Millwood) (2011) 0.79
The Stateville penitentiary malaria experiments: a case study in retrospective ethical assessment. Perspect Biol Med (2013) 0.78
The ethics of sham invasive intervention trials. Clin Trials (2009) 0.78
The ethics of research on enhancement interventions. Kennedy Inst Ethics J (2010) 0.78
Factors that influence practitioners' interpretations of evidence from alternative medicine trials: a factorial vignette experiment embedded in a national survey. Med Care (2010) 0.78
Viewpoint: Randomised controlled trials using invasive control interventions should be included in Cochrane Reviews. Cochrane Database Syst Rev (2011) 0.78
Understanding and translating the knowledge about placebo effects: the contribution of psychology. Curr Opin Psychiatry (2014) 0.77
Counterpoint: are donors after circulatory death really dead, and does it matter? No and not really. Chest (2010) 0.77
Placebo Effects and the Ethics of Therapeutic Communication: A Pragmatic Perspective. Kennedy Inst Ethics J (2016) 0.77
The patient's work. Camb Q Healthc Ethics (2007) 0.77
Evidence, errors, and ethics. Perspect Biol Med (2014) 0.76
Painful deception. Science (2004) 0.75
End-of-life care for patients with dementia. N Engl J Med (2004) 0.75
Treatment of acute migraine. Lancet (2002) 0.75
Academic-industrial relationships. N Engl J Med (2005) 0.75
Controversies about brain death. JAMA (2009) 0.75
Placebo research and the spirit of informed consent. Psychosom Med (2005) 0.75
To publish or not to publish? J Lab Clin Med (2005) 0.75
Justice and health care in the rheumatic diseases. HSS J (2005) 0.75
Direct-to-consumer advertising and physician prescribing. JAMA (2005) 0.75