Dirk Winkler

Author PubWeight™ 50.53‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 TP53 mutation and survival in chronic lymphocytic leukemia. J Clin Oncol 2010 3.26
2 Bendamustine combined with rituximab in patients with relapsed and/or refractory chronic lymphocytic leukemia: a multicenter phase II trial of the German Chronic Lymphocytic Leukemia Study Group. J Clin Oncol 2011 3.21
3 Bendamustine in combination with rituximab for previously untreated patients with chronic lymphocytic leukemia: a multicenter phase II trial of the German Chronic Lymphocytic Leukemia Study Group. J Clin Oncol 2012 3.00
4 Allogeneic stem cell transplantation provides durable disease control in poor-risk chronic lymphocytic leukemia: long-term clinical and MRD results of the German CLL Study Group CLL3X trial. Blood 2010 2.87
5 miR-34a as part of the resistance network in chronic lymphocytic leukemia. Blood 2008 2.58
6 Monoallelic TP53 inactivation is associated with poor prognosis in chronic lymphocytic leukemia: results from a detailed genetic characterization with long-term follow-up. Blood 2008 2.46
7 Additional genetic high-risk features such as 11q deletion, 17p deletion, and V3-21 usage characterize discordance of ZAP-70 and VH mutation status in chronic lymphocytic leukemia. J Clin Oncol 2006 2.15
8 Detailed analysis of p53 pathway defects in fludarabine-refractory chronic lymphocytic leukemia (CLL): dissecting the contribution of 17p deletion, TP53 mutation, p53-p21 dysfunction, and miR34a in a prospective clinical trial. Blood 2009 2.01
9 Subcutaneous alemtuzumab in fludarabine-refractory chronic lymphocytic leukemia: clinical results and prognostic marker analyses from the CLL2H study of the German Chronic Lymphocytic Leukemia Study Group. J Clin Oncol 2009 2.00
10 Clonal evolution in chronic lymphocytic leukemia: acquisition of high-risk genomic aberrations associated with unmutated VH, resistance to therapy, and short survival. Haematologica 2007 1.99
11 High-resolution genomic profiling of chronic lymphocytic leukemia reveals new recurrent genomic alterations. Blood 2012 1.58
12 Distinct gene expression patterns in chronic lymphocytic leukemia defined by usage of specific VH genes. Blood 2005 1.16
13 Intraoperative MRI to guide the resection of primary supratentorial glioblastoma multiforme--a quantitative radiological analysis. Neuroradiology 2005 1.15
14 NOTCH1, SF3B1, and TP53 mutations in fludarabine-refractory CLL patients treated with alemtuzumab: results from the CLL2H trial of the GCLLSG. Blood 2013 1.09
15 Small molecules inhibit the interaction of Nrf2 and the Keap1 Kelch domain through a non-covalent mechanism. Bioorg Med Chem 2013 1.07
16 A novel paradigm to trigger apoptosis in chronic lymphocytic leukemia. Cancer Res 2009 0.94
17 Rapid analysis of Forster resonance energy transfer by two-color global fluorescence correlation spectroscopy: trypsin proteinase reaction. Biophys J 2005 0.93
18 Gene expression factors as predictors of genetic risk and survival in chronic lymphocytic leukemia. Haematologica 2009 0.91
19 Effects of subthalamic nucleus stimulation on striatal dopaminergic transmission in patients with Parkinson's disease within one-year follow-up. J Neurol 2008 0.89
20 DNA damage-induced transcriptional program in CLL: biological and diagnostic implications for functional p53 testing. Blood 2010 0.89
21 Discovery and structure-activity relationship of potent and selective covalent inhibitors of transglutaminase 2 for Huntington's disease. J Med Chem 2012 0.87
22 BRAF mutations in chronic lymphocytic leukemia. Leuk Lymphoma 2012 0.87
23 Identification of novel Kv1.3 blockers using a fluorescent cell-based ion channel assay. J Biomol Screen 2005 0.85
24 Ala228 variant of trail receptor 1 affecting the ligand binding site is associated with chronic lymphocytic leukemia, mantle cell lymphoma, prostate cancer, head and neck squamous cell carcinoma and bladder cancer. Int J Cancer 2006 0.85
25 Development of a 1-microl scale assay for mitogen-activated kinase kinase 7 using 2-D fluorescence intensity distribution analysis anisotropy. J Biomol Screen 2002 0.83
26 Early autologous stem cell transplantation for chronic lymphocytic leukemia: long-term follow-up of the German CLL Study Group CLL3 trial. Blood 2012 0.83
27 Development of a series of aryl pyrimidine kynurenine monooxygenase inhibitors as potential therapeutic agents for the treatment of Huntington's disease. J Med Chem 2015 0.83
28 Property- and structure-guided discovery of a tetrahydroindazole series of interleukin-2 inducible T-cell kinase inhibitors. J Med Chem 2014 0.82
29 Fragment-based identification of Hsp90 inhibitors. ChemMedChem 2009 0.82
30 Sequential chemoimmunotherapy of fludarabine, mitoxantrone, and cyclophosphamide induction followed by alemtuzumab consolidation is effective in T-cell prolymphocytic leukemia. Cancer 2013 0.80
31 Mutation analysis of the TNFAIP3 (A20) tumor suppressor gene in CLL. Int J Cancer 2010 0.80
32 The impact of psychiatric comorbidity on the return to work in patients undergoing herniated disc surgery. J Occup Rehabil 2011 0.80
33 Peptide based adsorbers for therapeutic immunoadsorption. Ther Apher Dial 2003 0.79
34 Investigation of 3 industry-wide applied storage conditions for compound libraries. J Biomol Screen 2006 0.78
35 Investigation of time-dependency of intracranial brain shift and its relation to the extent of tumor removal using intra-operative MRI. Neurol Res 2003 0.77
36 Unusual penetrating cranio-orbital injury by a cut-off wheel. J Craniofac Surg 2004 0.77
37 Metabolism and pharmacokinetics of JM6 in mice: JM6 is not a prodrug for Ro-61-8048. Drug Metab Dispos 2012 0.76
38 Novel MK2 inhibitors by fragment screening. Comb Chem High Throughput Screen 2009 0.76
39 Increase of frequency in deep brain stimulation relieves apraxia of eyelid opening in patients with Parkinson's disease: case report. Neurosurgery 2008 0.75
40 A multiplexed approach to hit finding. Curr Opin Drug Discov Devel 2009 0.75
41 Correction: Pelvic Belt Effects on Health Outcomes and Functional Parameters of Patients with Sacroiliac Joint Pain. PLoS One 2015 0.75
42 Positional Relations of the Cervical Vagus Nerve Revisited. Neuromodulation 2017 0.75
43 A label-free LC/MS/MS-based enzymatic activity assay for the detection of genuine caspase inhibitors and SAR development. J Biomol Screen 2013 0.75
44 NEUROGATE: a new MR-compatible device for realizing minimally invasive treatment of intracerebral tumors. Comput Aided Surg 2004 0.75
45 NanoStore: a concept for logistical improvements of compound handling in high-throughput screening. J Biomol Screen 2005 0.75