Published in Nature on August 28, 2005
Polo-like kinases: conservation and divergence in their functions and regulation. Nat Rev Mol Cell Biol (2009) 4.09
Regulation of APC/C activators in mitosis and meiosis. Annu Rev Cell Dev Biol (2008) 2.46
Use of the novel Plk1 inhibitor ZK-thiazolidinone to elucidate functions of Plk1 in early and late stages of mitosis. Mol Biol Cell (2007) 2.38
The M phase kinase Greatwall (Gwl) promotes inactivation of PP2A/B55delta, a phosphatase directed against CDK phosphosites. Mol Biol Cell (2009) 2.09
Roles of Greatwall kinase in the regulation of cdc25 phosphatase. Mol Biol Cell (2008) 1.68
The transforming parasite Theileria co-opts host cell mitotic and central spindles to persist in continuously dividing cells. PLoS Biol (2010) 1.60
Plk1 regulates mitotic Aurora A function through betaTrCP-dependent degradation of hBora. Chromosoma (2008) 1.60
Mouse Emi2 is required to enter meiosis II by reestablishing cyclin B1 during interkinesis. J Cell Biol (2006) 1.55
Mammalian Emi2 mediates cytostatic arrest and transduces the signal for meiotic exit via Cdc20. EMBO J (2006) 1.49
The roles of Ca2+, downstream protein kinases, and oscillatory signaling in regulating fertilization and the activation of development. Dev Biol (2008) 1.34
A role for Cdc2- and PP2A-mediated regulation of Emi2 in the maintenance of CSF arrest. Curr Biol (2007) 1.27
Spatiotemporal regulation of the anaphase-promoting complex in mitosis. Nat Rev Mol Cell Biol (2015) 1.25
CaMKII and polo-like kinase 1 sequentially phosphorylate the cytostatic factor Emi2/XErp1 to trigger its destruction and meiotic exit. Proc Natl Acad Sci U S A (2006) 1.20
Restarting life: fertilization and the transition from meiosis to mitosis. Nat Rev Mol Cell Biol (2013) 1.18
Prophase I arrest and progression to metaphase I in mouse oocytes are controlled by Emi1-dependent regulation of APC(Cdh1). J Cell Biol (2006) 1.16
Regulation of postsynaptic RapGAP SPAR by Polo-like kinase 2 and the SCFbeta-TRCP ubiquitin ligase in hippocampal neurons. J Biol Chem (2008) 1.10
Developmental control of oocyte maturation and egg activation in metazoan models. Cold Spring Harb Perspect Biol (2011) 1.09
Control of Emi2 activity and stability through Mos-mediated recruitment of PP2A. Proc Natl Acad Sci U S A (2007) 1.09
Pumilio 2 controls translation by competing with eIF4E for 7-methyl guanosine cap recognition. RNA (2009) 1.08
Dephosphorylation of Cdc20 is required for its C-box-dependent activation of the APC/C. EMBO J (2012) 1.07
Mouse Emi2 as a distinctive regulatory hub in second meiotic metaphase. Development (2010) 1.07
A zinc-dependent mechanism regulates meiotic progression in mammalian oocytes. Biol Reprod (2012) 1.04
State of the APC/C: organization, function, and structure. Crit Rev Biochem Mol Biol (2011) 1.02
Emi2 inhibition of the anaphase-promoting complex/cyclosome absolutely requires Emi2 binding via the C-terminal RL tail. Mol Biol Cell (2010) 1.01
How eggs arrest at metaphase II: MPF stabilisation plus APC/C inhibition equals Cytostatic Factor. Cell Div (2007) 1.01
Control of oocyte growth and meiotic maturation in Caenorhabditis elegans. Adv Exp Med Biol (2013) 1.00
Mechanism of degradation of CPEB during Xenopus oocyte maturation. Proc Natl Acad Sci U S A (2007) 0.99
Second meiotic arrest and exit in frogs and mice. EMBO Rep (2008) 0.98
Inositol 1,4,5-trisphosphate receptor 1, a widespread Ca2+ channel, is a novel substrate of polo-like kinase 1 in eggs. Dev Biol (2008) 0.94
Protein phosphorylation changes reveal new candidates in the regulation of egg activation and early embryogenesis in D. melanogaster. Dev Biol (2012) 0.92
Cdc2 and Mos regulate Emi2 stability to promote the meiosis I-meiosis II transition. Mol Biol Cell (2008) 0.92
Molecular changes during egg activation. Curr Top Dev Biol (2013) 0.90
Regulation of inositol 1,4,5-trisphosphate receptor type 1 function during oocyte maturation by MPM-2 phosphorylation. Cell Calcium (2009) 0.88
Modulation of cell cycle control during oocyte-to-embryo transitions. EMBO J (2013) 0.87
Ca(2+) signaling, genes and the cell cycle. Cell Calcium (2010) 0.86
Mes1 controls the meiosis I to meiosis II transition by distinctly regulating the anaphase-promoting complex/cyclosome coactivators Fzr1/Mfr1 and Slp1 in fission yeast. Mol Biol Cell (2011) 0.86
CaM kinase II initiates meiotic spindle depolymerization independently of APC/C activation. J Cell Biol (2008) 0.86
Mos in the oocyte: how to use MAPK independently of growth factors and transcription to control meiotic divisions. J Signal Transduct (2010) 0.85
Oocyte maturation failure: a syndrome of bad eggs. Fertil Steril (2010) 0.84
Dimethyl sulfoxide inhibits spontaneous oocyte fragmentation and delays inactivation of maturation promoting factor (MPF) during the prolonged culture of ovulated murine oocytes in vitro. Cytotechnology (2011) 0.82
Regulation of store-operated Ca2+ entry during the cell cycle. J Cell Sci (2010) 0.81
Does the potential for chaos constrain the embryonic cell-cycle oscillator? PLoS Comput Biol (2011) 0.81
Pig oocyte activation using a Zn²⁺ chelator, TPEN. Theriogenology (2015) 0.78
Release from meiotic arrest in ascidian eggs requires the activity of two phosphatases but not CaMKII. Development (2013) 0.78
PP2A as a mercenary for warring kinases in the egg. Proc Natl Acad Sci U S A (2007) 0.78
Non-proteolytic ubiquitylation counteracts the APC/C-inhibitory function of XErp1. EMBO Rep (2011) 0.78
Developmental biology: cell cycle unleashed. Nature (2005) 0.76
Vertebrate Reproduction. Cold Spring Harb Perspect Biol (2015) 0.76
Canonical and Alternative Pathways in Cyclin-Dependent Kinase 1/Cyclin B Inactivation upon M-Phase Exit in Xenopus laevis Cell-Free Extracts. Enzyme Res (2011) 0.75
Vitamin D3 suppresses morphological evolution of the cribriform cancerous phenotype. Oncotarget (2016) 0.75
Xenopus extract approaches to studying microtubule organization and signaling in cytokinesis. Methods Cell Biol (2016) 0.75
Transmembrane signal transduction in oocyte maturation and fertilization: focusing on Xenopus laevis as a model animal. Int J Mol Sci (2014) 0.75
Structural basis for recognition of Emi2 by Polo-like kinase 1 and development of peptidomimetics blocking oocyte maturation and fertilization. Sci Rep (2015) 0.75
Transcriptomic features of Pecten maximus oocyte quality and maturation. PLoS One (2017) 0.75
Calcium signaling and meiotic exit at fertilization in Xenopus egg. Int J Mol Sci (2014) 0.75
Cyclin A2 modulates kinetochore-microtubule attachment in meiosis II. J Cell Biol (2017) 0.75
Proteomic characterization of the human centrosome by protein correlation profiling. Nature (2003) 8.74
Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. Sci Signal (2010) 8.61
Polo-like kinases and the orchestration of cell division. Nat Rev Mol Cell Biol (2004) 7.22
Stattic: a small-molecule inhibitor of STAT3 activation and dimerization. Chem Biol (2006) 6.38
The Polo kinase Plk4 functions in centriole duplication. Nat Cell Biol (2005) 5.84
Plk4-induced centriole biogenesis in human cells. Dev Cell (2007) 5.68
The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4. Nat Genet (2006) 5.36
Role of Hec1 in spindle checkpoint signaling and kinetochore recruitment of Mad1/Mad2. Science (2002) 4.94
Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells. EMBO J (2002) 4.54
Active cyclin B1-Cdk1 first appears on centrosomes in prophase. Nat Cell Biol (2003) 4.31
Exploring the functional interactions between Aurora B, INCENP, and survivin in mitosis. Mol Biol Cell (2003) 4.28
Structure of a Survivin-Borealin-INCENP core complex reveals how chromosomal passengers travel together. Cell (2007) 3.98
Cep164, a novel centriole appendage protein required for primary cilium formation. J Cell Biol (2007) 3.88
PICH, a centromere-associated SNF2 family ATPase, is regulated by Plk1 and required for the spindle checkpoint. Cell (2007) 3.80
Human TPX2 is required for targeting Aurora-A kinase to the spindle. J Cell Biol (2002) 3.69
The dissociation of cohesin from chromosomes in prophase is regulated by Polo-like kinase. Mol Cell (2002) 3.65
The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1. Oncogene (2005) 3.64
Phosphoproteome analysis of the human mitotic spindle. Proc Natl Acad Sci U S A (2006) 3.56
Borealin: a novel chromosomal passenger required for stability of the bipolar mitotic spindle. J Cell Biol (2004) 3.49
Cell cycle regulation of central spindle assembly. Nature (2004) 3.27
HURP is a Ran-importin beta-regulated protein that stabilizes kinetochore microtubules in the vicinity of chromosomes. Curr Biol (2006) 3.21
5'-Triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma. Nat Med (2008) 3.13
Phosphorylation of mitotic kinesin-like protein 2 by polo-like kinase 1 is required for cytokinesis. J Cell Biol (2003) 3.12
Aurora kinases link chromosome segregation and cell division to cancer susceptibility. Curr Opin Genet Dev (2004) 2.96
Universal and confident phosphorylation site localization using phosphoRS. J Proteome Res (2011) 2.93
Tension-sensitive Plk1 phosphorylation on BubR1 regulates the stability of kinetochore microtubule interactions. Genes Dev (2007) 2.92
Control of centriole length by CPAP and CP110. Curr Biol (2009) 2.67
Heterochromatin formation in Drosophila is initiated through active removal of H3K4 methylation by the LSD1 homolog SU(VAR)3-3. Mol Cell (2007) 2.66
Centrosome-associated Chk1 prevents premature activation of cyclin-B-Cdk1 kinase. Nat Cell Biol (2004) 2.63
Choice of Plk1 docking partners during mitosis and cytokinesis is controlled by the activation state of Cdk1. Nat Cell Biol (2007) 2.54
The human kinesin Kif18A is a motile microtubule depolymerase essential for chromosome congression. Curr Biol (2007) 2.53
Relocation of Aurora B from centromeres to the central spindle at the metaphase to anaphase transition requires MKlp2. J Cell Biol (2004) 2.44
Human Mps1 kinase is required for the spindle assembly checkpoint but not for centrosome duplication. EMBO J (2002) 2.41
Complex formation of Plk1 and INCENP required for metaphase-anaphase transition. Nat Cell Biol (2005) 2.41
Human Asf1 and CAF-1 interact and synergize in a repair-coupled nucleosome assembly pathway. EMBO Rep (2002) 2.40
Cdk1/Erk2- and Plk1-dependent phosphorylation of a centrosome protein, Cep55, is required for its recruitment to midbody and cytokinesis. Dev Cell (2005) 2.40
Rootletin forms centriole-associated filaments and functions in centrosome cohesion. J Cell Biol (2005) 2.38
Use of the novel Plk1 inhibitor ZK-thiazolidinone to elucidate functions of Plk1 in early and late stages of mitosis. Mol Biol Cell (2007) 2.38
The crystal structure of the human polo-like kinase-1 polo box domain and its phospho-peptide complex. EMBO J (2003) 2.31
Proteome analysis of the human mitotic spindle. Mol Cell Proteomics (2004) 2.31
Aurora-B phosphorylates Histone H3 at serine28 with regard to the mitotic chromosome condensation. Genes Cells (2002) 2.28
Molecular basis of tubulin transport within the cilium by IFT74 and IFT81. Science (2013) 2.25
3D-structured illumination microscopy provides novel insight into architecture of human centrosomes. Biol Open (2012) 2.23
Polo-like kinase 1 regulates Nlp, a centrosome protein involved in microtubule nucleation. Dev Cell (2003) 2.18
The forkhead-associated domain protein Cep170 interacts with Polo-like kinase 1 and serves as a marker for mature centrioles. Mol Biol Cell (2004) 2.17
Timely anaphase onset requires a novel spindle and kinetochore complex comprising Ska1 and Ska2. EMBO J (2006) 2.14
Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods. EMBO J (2011) 2.14
Polymorphisms in melanoma differentiation-associated gene 5 link protein function to clearance of hepatitis C virus. Hepatology (2015) 2.11
Different Plk1 functions show distinct dependencies on Polo-Box domain-mediated targeting. Mol Biol Cell (2005) 2.09
KIF14 and citron kinase act together to promote efficient cytokinesis. J Cell Biol (2006) 2.06
Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins. J Biol Chem (2009) 2.02
Centromere targeting of the chromosomal passenger complex requires a ternary subcomplex of Borealin, Survivin, and the N-terminal domain of INCENP. Mol Biol Cell (2006) 1.94
The Plk1-dependent phosphoproteome of the early mitotic spindle. Mol Cell Proteomics (2010) 1.91
Persistence of DNA threads in human anaphase cells suggests late completion of sister chromatid decatenation. Chromosoma (2007) 1.78
Cep68 and Cep215 (Cdk5rap2) are required for centrosome cohesion. J Cell Sci (2007) 1.78
Stable kinetochore-microtubule interactions depend on the Ska complex and its new component Ska3/C13Orf3. EMBO J (2009) 1.76
Plk4 trans-autophosphorylation regulates centriole number by controlling betaTrCP-mediated degradation. J Cell Sci (2010) 1.74
The mechanism regulating the dissociation of the centrosomal protein C-Nap1 from mitotic spindle poles. J Cell Sci (2002) 1.73
The regulatory domain of the RIG-I family ATPase LGP2 senses double-stranded RNA. Nucleic Acids Res (2009) 1.72
Human Tousled like kinases are targeted by an ATM- and Chk1-dependent DNA damage checkpoint. EMBO J (2003) 1.67
Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly. J Cell Biol (2009) 1.64
Cell cycle-regulated phosphorylation of the Xenopus polo-like kinase Plx1. J Biol Chem (2002) 1.63
Spatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for context-dependent mitotic signaling. Sci Signal (2011) 1.62
Influence of human Ect2 depletion and overexpression on cleavage furrow formation and abscission. J Cell Sci (2006) 1.62
Cell-cycle-regulated expression of STIL controls centriole number in human cells. J Cell Sci (2012) 1.60
The transforming parasite Theileria co-opts host cell mitotic and central spindles to persist in continuously dividing cells. PLoS Biol (2010) 1.60
Plk1 regulates mitotic Aurora A function through betaTrCP-dependent degradation of hBora. Chromosoma (2008) 1.60
Astrin is required for the maintenance of sister chromatid cohesion and centrosome integrity. J Cell Biol (2007) 1.59
Aurora-C kinase is a novel chromosomal passenger protein that can complement Aurora-B kinase function in mitotic cells. Cell Motil Cytoskeleton (2004) 1.59
Modulated microtubule dynamics enable Hklp2/Kif15 to assemble bipolar spindles. Cell Cycle (2011) 1.58
Xenopus polo-like kinase Plx1 regulates XErp1, a novel inhibitor of APC/C activity. Genes Dev (2005) 1.57
Human Cep192 and Cep152 cooperate in Plk4 recruitment and centriole duplication. J Cell Sci (2013) 1.55
Quantitative analysis of the human spindle phosphoproteome at distinct mitotic stages. J Proteome Res (2009) 1.53
Cdk1 negatively regulates midzone localization of the mitotic kinesin Mklp2 and the chromosomal passenger complex. Curr Biol (2009) 1.52
Aurora-B regulates the cleavage furrow-specific vimentin phosphorylation in the cytokinetic process. J Biol Chem (2002) 1.47
A complex of two centrosomal proteins, CAP350 and FOP, cooperates with EB1 in microtubule anchoring. Mol Biol Cell (2005) 1.45
Natural product-derived modulators of cell cycle progression and viral entry by enantioselective oxa Diels-Alder reactions on the solid phase. Chem Biol (2007) 1.43
Uncoupling of the spindle-checkpoint and chromosome-congression functions of BubR1. J Cell Sci (2010) 1.42
High-content screening and profiling of drug activity in an automated centrosome-duplication assay. Chembiochem (2005) 1.38
Centrosome-associated NDR kinase regulates centrosome duplication. Mol Cell (2007) 1.37
Phosphorylation by Cdk1 induces Plk1-mediated vimentin phosphorylation during mitosis. J Cell Biol (2005) 1.34
MASPECTRAS: a platform for management and analysis of proteomics LC-MS/MS data. BMC Bioinformatics (2007) 1.34
Re-examination of siRNA specificity questions role of PICH and Tao1 in the spindle checkpoint and identifies Mad2 as a sensitive target for small RNAs. Chromosoma (2009) 1.33
Suppression of Tousled-like kinase activity after DNA damage or replication block requires ATM, NBS1 and Chk1. Oncogene (2003) 1.33
Inducible DNA-loop formation blocks transcriptional activation by an SV40 enhancer. EMBO J (2005) 1.33
Topology and organization of the Salmonella typhimurium type III secretion needle complex components. PLoS Pathog (2010) 1.32
Isotope-labeled cross-linkers and Fourier transform ion cyclotron resonance mass spectrometry for structural analysis of a protein/peptide complex. J Am Soc Mass Spectrom (2006) 1.31
Kinetochore localization and microtubule interaction of the human spindle checkpoint kinase Mps1. Chromosoma (2004) 1.30
Sgt1 is required for human kinetochore assembly. EMBO Rep (2004) 1.30
Centromere DNA decatenation depends on cohesin removal and is required for mammalian cell division. J Cell Sci (2010) 1.28
Tousled-like kinase functions with the chromatin assembly pathway regulating nuclear divisions. Genes Dev (2003) 1.27
Cytostatic factor: an activity that puts the cell cycle on hold. J Cell Sci (2006) 1.27
Coordinate regulation of the mother centriole component nlp by nek2 and plk1 protein kinases. Mol Cell Biol (2005) 1.26
Phosphorylation of Nlp by Plk1 negatively regulates its dynein-dynactin-dependent targeting to the centrosome. J Cell Sci (2005) 1.25
The autoregulated instability of Polo-like kinase 4 limits centrosome duplication to once per cell cycle. Genes Dev (2012) 1.23