Globular amyloid beta-peptide oligomer - a homogenous and stable neuropathological protein in Alzheimer's disease.

PubWeight™: 3.06‹?› | Rank: Top 1%

🔗 View Article (PMID 16135089)

Published in J Neurochem on August 31, 2005

Authors

Stefan Barghorn1, Volker Nimmrich, Andreas Striebinger, Carsten Krantz, Patrick Keller, Bodo Janson, Michael Bahr, Martin Schmidt, Robert S Bitner, John Harlan, Eve Barlow, Ulrich Ebert, Heinz Hillen

Author Affiliations

1: Neuroscience Discovery Research, Abbott GmbH and Co. KG, Ludwigshafen, Germany.

Articles citing this

(truncated to the top 100)

The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes. Nat Neurosci (2012) 4.92

Structural classification of toxic amyloid oligomers. J Biol Chem (2008) 4.16

Structural conversion of neurotoxic amyloid-beta(1-42) oligomers to fibrils. Nat Struct Mol Biol (2010) 3.75

Effects of secreted oligomers of amyloid beta-protein on hippocampal synaptic plasticity: a potent role for trimers. J Physiol (2006) 3.74

Amyloid-β protein oligomerization and the importance of tetramers and dodecamers in the aetiology of Alzheimer's disease. Nat Chem (2009) 3.66

Lipids revert inert Abeta amyloid fibrils to neurotoxic protofibrils that affect learning in mice. EMBO J (2007) 2.39

Soluble fibrillar oligomer levels are elevated in Alzheimer's disease brain and correlate with cognitive dysfunction. Neurobiol Dis (2009) 2.12

Soluble Aβ oligomer production and toxicity. J Neurochem (2011) 1.83

Neurotrophic factors in Alzheimer's disease: role of axonal transport. Genes Brain Behav (2008) 1.80

Alzheimer's disease: synaptic dysfunction and Abeta. Mol Neurodegener (2009) 1.73

Stabilization of neurotoxic Alzheimer amyloid-beta oligomers by protein engineering. Proc Natl Acad Sci U S A (2010) 1.72

The Aβ oligomer hypothesis for synapse failure and memory loss in Alzheimer's disease. Neurobiol Learn Mem (2011) 1.63

Polymorphism in Alzheimer Abeta amyloid organization reflects conformational selection in a rugged energy landscape. Chem Rev (2010) 1.62

Increased accumulation of intraneuronal amyloid beta in HIV-infected patients. J Neuroimmune Pharmacol (2009) 1.55

Toxic fibrillar oligomers of amyloid-β have cross-β structure. Proc Natl Acad Sci U S A (2012) 1.53

Isolation and characterization of patient-derived, toxic, high mass amyloid beta-protein (Abeta) assembly from Alzheimer disease brains. J Biol Chem (2009) 1.52

Aβ oligomer-induced synapse degeneration in Alzheimer's disease. Cell Mol Neurobiol (2011) 1.33

Positioning of the Alzheimer Abeta(1-40) peptide in SDS micelles using NMR and paramagnetic probes. J Biomol NMR (2007) 1.30

Alzheimer's disease, β-amyloid, glutamate, NMDA receptors and memantine--searching for the connections. Br J Pharmacol (2012) 1.26

Structure-function relationships of pre-fibrillar protein assemblies in Alzheimer's disease and related disorders. Curr Alzheimer Res (2008) 1.26

Amyloid-beta-induced ion flux in artificial lipid bilayers and neuronal cells: resolving a controversy. Neurotox Res (2009) 1.24

Role of electrostatic interactions in amyloid beta-protein (A beta) oligomer formation: a discrete molecular dynamics study. Biophys J (2007) 1.22

Amyloid-β as a modulator of synaptic plasticity. J Alzheimers Dis (2010) 1.22

New ELISAs with high specificity for soluble oligomers of amyloid β-protein detect natural Aβ oligomers in human brain but not CSF. Alzheimers Dement (2013) 1.22

Intracellular accumulation of amyloid-Beta - a predictor for synaptic dysfunction and neuron loss in Alzheimer's disease. Front Aging Neurosci (2010) 1.20

Memantine improves cognition and reduces Alzheimer's-like neuropathology in transgenic mice. Am J Pathol (2009) 1.19

Distinct synthetic Aβ prion strains producing different amyloid deposits in bigenic mice. Proc Natl Acad Sci U S A (2014) 1.18

Size-dependent neurotoxicity of beta-amyloid oligomers. Arch Biochem Biophys (2010) 1.17

Triterpenoid CDDO-methylamide improves memory and decreases amyloid plaques in a transgenic mouse model of Alzheimer's disease. J Neurochem (2009) 1.17

Lipid Rafts: Linking Alzheimer's Amyloid-β Production, Aggregation, and Toxicity at Neuronal Membranes. Int J Alzheimers Dis (2010) 1.17

Cystatin C protects neuronal cells from amyloid-beta-induced toxicity. J Alzheimers Dis (2010) 1.17

Distinct cerebrospinal fluid amyloid beta peptide signatures in sporadic and PSEN1 A431E-associated familial Alzheimer's disease. Mol Neurodegener (2010) 1.15

Amyloid-β oligomer specificity mediated by the IgM isotype--implications for a specific protective mechanism exerted by endogenous auto-antibodies. PLoS One (2010) 1.10

Aβ40 oligomers identified as a potential biomarker for the diagnosis of Alzheimer's disease. PLoS One (2010) 1.10

Passive anti-amyloid immunotherapy in Alzheimer's disease: What are the most promising targets? Immun Ageing (2013) 1.08

Differences in β-strand populations of monomeric Aβ40 and Aβ42. Biophys J (2013) 1.08

Combining the rapid MTT formazan exocytosis assay and the MC65 protection assay led to the discovery of carbazole analogs as small molecule inhibitors of Abeta oligomer-induced cytotoxicity. Brain Res (2006) 1.07

Amyloid β-protein oligomers and Alzheimer's disease. Alzheimers Res Ther (2013) 1.07

The essential role of p53-up-regulated modulator of apoptosis (Puma) and its regulation by FoxO3a transcription factor in β-amyloid-induced neuron death. J Biol Chem (2014) 1.06

Complete phenotypic recovery of an Alzheimer's disease model by a quinone-tryptophan hybrid aggregation inhibitor. PLoS One (2010) 1.06

Investigating how peptide length and a pathogenic mutation modify the structural ensemble of amyloid beta monomer. Biophys J (2012) 1.02

Orally administrated cinnamon extract reduces β-amyloid oligomerization and corrects cognitive impairment in Alzheimer's disease animal models. PLoS One (2011) 1.01

Evaluating amyloid-β oligomers in cerebrospinal fluid as a biomarker for Alzheimer's disease. PLoS One (2013) 1.01

Two distinct amyloid beta-protein (Abeta) assembly pathways leading to oligomers and fibrils identified by combined fluorescence correlation spectroscopy, morphology, and toxicity analyses. J Biol Chem (2011) 1.00

Self assembly of short aromatic peptides into amyloid fibrils and related nanostructures. Prion (2007) 0.98

Amyloid structure and assembly: insights from scanning transmission electron microscopy. J Struct Biol (2010) 0.98

Stabilization of neurotoxic soluble beta-sheet-rich conformations of the Alzheimer's disease amyloid-beta peptide. Biophys J (2007) 0.98

A novel inhibitor of amyloid β (Aβ) peptide aggregation: from high throughput screening to efficacy in an animal model of Alzheimer disease. J Biol Chem (2012) 0.98

Specific recognition of biologically active amyloid-β oligomers by a new surface plasmon resonance-based immunoassay and an in vivo assay in Caenorhabditis elegans. J Biol Chem (2012) 0.97

Structural insights into Aβ42 oligomers using site-directed spin labeling. J Biol Chem (2013) 0.97

Soluble aggregates of the amyloid-beta protein selectively stimulate permeability in human brain microvascular endothelial monolayers. J Neurochem (2008) 0.97

FoxO3a is activated and executes neuron death via Bim in response to β-amyloid. Cell Death Dis (2013) 0.96

Large aggregates are the major soluble Aβ species in AD brain fractionated with density gradient ultracentrifugation. PLoS One (2012) 0.96

c-Jun N-terminal kinase regulates soluble Aβ oligomers and cognitive impairment in AD mouse model. J Biol Chem (2011) 0.96

An improved method for generating consistent soluble amyloid-beta oligomer preparations for in vitro neurotoxicity studies. J Neurosci Methods (2010) 0.95

A monoclonal antibody against synthetic Aβ dimer assemblies neutralizes brain-derived synaptic plasticity-disrupting Aβ. J Neurochem (2011) 0.95

Distinct effects of Zn2+, Cu2+, Fe3+, and Al3+ on amyloid-beta stability, oligomerization, and aggregation: amyloid-beta destabilization promotes annular protofibril formation. J Biol Chem (2011) 0.95

Modes of Aβ toxicity in Alzheimer's disease. Cell Mol Life Sci (2011) 0.94

Formation of soluble amyloid oligomers and amyloid fibrils by the multifunctional protein vitronectin. Mol Neurodegener (2008) 0.93

Endocytic pathways mediating oligomeric Abeta42 neurotoxicity. Mol Neurodegener (2010) 0.92

NMDA-receptor activation but not ion flux is required for amyloid-beta induced synaptic depression. PLoS One (2013) 0.92

Assembly and interrogation of Alzheimer's disease genetic networks reveal novel regulators of progression. PLoS One (2015) 0.92

Amyloid plaque and neurofibrillary tangle pathology in a regulatable mouse model of Alzheimer's disease. Am J Pathol (2008) 0.92

Synthesis and Purification of Highly Hydrophobic Peptides Derived from the C-Terminus of Amyloid β-Protein. Open Biotechnol J (2008) 0.92

Non-esterified fatty acids generate distinct low-molecular weight amyloid-β (Aβ42) oligomers along pathway different from fibril formation. PLoS One (2011) 0.91

Structural basis for Aβ1–42 toxicity inhibition by Aβ C-terminal fragments: discrete molecular dynamics study. J Mol Biol (2011) 0.91

Unraveling the early events of amyloid-β protein (Aβ) aggregation: techniques for the determination of Aβ aggregate size. Int J Mol Sci (2012) 0.91

Molecular basis of β-amyloid oligomer recognition with a conformational antibody fragment. Proc Natl Acad Sci U S A (2012) 0.91

Calcium channel blockers and dementia. Br J Pharmacol (2013) 0.91

A chemical screening approach reveals that indole fluorescence is quenched by pre-fibrillar but not fibrillar amyloid-beta. Bioorg Med Chem Lett (2009) 0.90

Polymorphic C-terminal beta-sheet interactions determine the formation of fibril or amyloid beta-derived diffusible ligand-like globulomer for the Alzheimer Abeta42 dodecamer. J Biol Chem (2010) 0.90

Knockdown of BACE1-AS Nonprotein-Coding Transcript Modulates Beta-Amyloid-Related Hippocampal Neurogenesis. Int J Alzheimers Dis (2011) 0.90

Polymorphic structures of Alzheimer's β-amyloid globulomers. PLoS One (2011) 0.89

Antiparallel β-Sheet Structure within the C-Terminal Region of 42-Residue Alzheimer's Amyloid-β Peptides When They Form 150-kDa Oligomers. J Mol Biol (2015) 0.89

Abeta mediated diminution of MTT reduction--an artefact of single cell culture? PLoS One (2008) 0.88

Beta-barrel models of soluble amyloid beta oligomers and annular protofibrils. Proteins (2010) 0.88

Successful adjuvant-free vaccination of BALB/c mice with mutated amyloid beta peptides. BMC Neurosci (2008) 0.88

Prion-Protein-interacting Amyloid-β Oligomers of High Molecular Weight Are Tightly Correlated with Memory Impairment in Multiple Alzheimer Mouse Models. J Biol Chem (2015) 0.88

Apolipoprotein E3 (ApoE3) but not ApoE4 protects against synaptic loss through increased expression of protein kinase C epsilon. J Biol Chem (2012) 0.88

Profiles of SUMO and ubiquitin conjugation in an Alzheimer's disease model. Neurosci Lett (2011) 0.87

A glycine zipper motif mediates the formation of toxic β-amyloid oligomers in vitro and in vivo. Mol Neurodegener (2011) 0.87

Neuronal caspase 2 activity and function requires RAIDD, but not PIDD. Biochem J (2012) 0.86

Targeting the proper amyloid-beta neuronal toxins: a path forward for Alzheimer's disease immunotherapeutics. Alzheimers Res Ther (2014) 0.86

Efficient derivation of cortical glutamatergic neurons from human pluripotent stem cells: a model system to study neurotoxicity in Alzheimer's disease. Neurobiol Dis (2013) 0.86

An update on the toxicity of Abeta in Alzheimer's disease. Neuropsychiatr Dis Treat (2008) 0.85

Antiparallel triple-strand architecture for prefibrillar Aβ42 oligomers. J Biol Chem (2014) 0.85

Cu K-edge X-ray absorption spectroscopy reveals differential copper coordination within amyloid-β oligomers compared to amyloid-β monomers. Chem Commun (Camb) (2010) 0.85

Early diagnostics and therapeutics for Alzheimer's disease--how early can we get there? Expert Rev Neurother (2006) 0.84

A β-amyloid oligomer directly modulates P/Q-type calcium currents in Xenopus oocytes. Br J Pharmacol (2012) 0.84

Sertad1 plays an essential role in developmental and pathological neuron death. J Neurosci (2010) 0.84

Effective anti-Alzheimer Aβ therapy involves depletion of specific Aβ oligomer subtypes. Neurol Neuroimmunol Neuroinflamm (2016) 0.84

Is abeta a sufficient biomarker for monitoring anti-abeta clinical studies? A critical review. Front Aging Neurosci (2013) 0.83

Assessing the causes and consequences of co-polymerization in amyloid formation. Prion (2013) 0.83

hESC-secreted proteins can be enriched for multiple regenerative therapies by heparin-binding. Aging (Albany NY) (2013) 0.83

Advances on the understanding of the origins of synaptic pathology in AD. Curr Genomics (2007) 0.83

Rationally designed turn promoting mutation in the amyloid-β peptide sequence stabilizes oligomers in solution. PLoS One (2011) 0.82

Formation of Toxic Amyloid Fibrils by Amyloid β-Protein on Ganglioside Clusters. Int J Alzheimers Dis (2011) 0.82

Estrogen amelioration of Aβ-induced defects in mitochondria is mediated by mitochondrial signaling pathway involving ERβ, AKAP and Drp1. Brain Res (2015) 0.81

Aβ42 assembles into specific β-barrel pore-forming oligomers in membrane-mimicking environments. Proc Natl Acad Sci U S A (2016) 0.81

Self-propagative replication of Aβ oligomers suggests potential transmissibility in Alzheimer disease. PLoS One (2014) 0.81

Articles by these authors

Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts. J Cell Biol (2003) 4.71

Alzheimer's disease beta-amyloid peptides are released in association with exosomes. Proc Natl Acad Sci U S A (2006) 3.98

Ambulatory blood pressure changes after renal sympathetic denervation in patients with resistant hypertension. Circulation (2013) 3.44

Structural characterization of a soluble amyloid beta-peptide oligomer. Biochemistry (2009) 2.31

Cellular and network mechanisms underlying spontaneous sharp wave-ripple complexes in mouse hippocampal slices. J Physiol (2003) 1.76

Spinal antinociceptive effects of cyclooxygenase inhibition during inflammation: Involvement of prostaglandins and endocannabinoids. Pain (2009) 1.74

Pelvic organ prolapse in fibulin-5 knockout mice: pregnancy-induced changes in elastic fiber homeostasis in mouse vagina. Am J Pathol (2007) 1.74

Randomized comparison between open irrigation technology and intracardiac-echo-guided energy delivery for pulmonary vein antrum isolation: procedural parameters, outcomes, and the effect on esophageal injury. J Cardiovasc Electrophysiol (2007) 1.73

The ephrin receptor tyrosine kinase A2 is a cellular receptor for Kaposi's sarcoma–associated herpesvirus. Nat Med (2012) 1.72

The three-dimensional structures of antagonistic and agonistic forms of the glucocorticoid receptor ligand-binding domain: RU-486 induces a transconformation that leads to active antagonism. J Biol Chem (2003) 1.61

Rab10 is involved in basolateral transport in polarized Madin-Darby canine kidney cells. Traffic (2006) 1.61

Patients with rheumatoid arthritis and systemic lupus erythematosus have increased renal excretion of mitogenic estrogens in relation to endogenous antiestrogens. J Rheumatol (2004) 1.58

Amyloid beta oligomers (A beta(1-42) globulomer) suppress spontaneous synaptic activity by inhibition of P/Q-type calcium currents. J Neurosci (2008) 1.54

Predictors of treatment in acute coronary syndromes in the elderly: impact on decision making and clinical outcome after interventional versus conservative treatment. Catheter Cardiovasc Interv (2012) 1.53

Microcircuits of functionally identified neurons in the rat medial entorhinal cortex. Neuron (2011) 1.51

Schizophrenia and depression: challenging the paradigm of two separate diseases--a controlled study of schizophrenia, depression and healthy controls. Schizophr Res (2005) 1.44

Rescue-stenting of an occluded lateral coronary sinus branch for recanalization after dissection during cardiac resynchronization device implantation. Europace (2008) 1.38

Vaccine immunogenicity in injecting drug users. Lancet Infect Dis (2009) 1.37

Human myometrial gene expression before and during parturition. Biol Reprod (2004) 1.36

Reduced spine density in specific regions of CA1 pyramidal neurons in two transgenic mouse models of Alzheimer's disease. J Neurosci (2011) 1.36

Dendritic transport and localization of protein kinase Mzeta mRNA: implications for molecular memory consolidation. J Biol Chem (2004) 1.34

The septation apparatus, an autonomous system in budding yeast. Mol Biol Cell (2002) 1.26

Localization of histamine H4 receptors in the central nervous system of human and rat. Brain Res (2008) 1.24

Abeta-globulomers are formed independently of the fibril pathway. Neurobiol Dis (2008) 1.23

Generation and therapeutic efficacy of highly oligomer-specific beta-amyloid antibodies. J Neurosci (2010) 1.20

Is Alzheimer's disease a result of presynaptic failure? Synaptic dysfunctions induced by oligomeric beta-amyloid. Rev Neurosci (2009) 1.15

Inhibition of APP trafficking by tau protein does not increase the generation of amyloid-beta peptides. Traffic (2006) 1.12

Morphology of far-field electrograms and antitachycardia pacing effectiveness among fast ventricular tachycardias occurring in ICD patients: the role of other discriminators. J Cardiovasc Electrophysiol (2014) 1.08

A randomized, multicenter, single-blinded trial comparing paclitaxel-coated balloon angioplasty with plain balloon angioplasty in drug-eluting stent restenosis: the PEPCAD-DES study. J Am Coll Cardiol (2012) 1.07

The early course of schizophrenia and depression*. Eur Arch Psychiatry Clin Neurosci (2005) 1.07

Magnet application in ICD patients. Pacing Clin Electrophysiol (2014) 1.07

Artificial muscles based on liquid crystal elastomers. Philos Trans A Math Phys Eng Sci (2006) 1.04

Increased estrogen formation and estrogen to androgen ratio in the synovial fluid of patients with rheumatoid arthritis. J Rheumatol (2003) 1.03

Micron-sized main-chain liquid crystalline elastomer actuators with ultralarge amplitude contractions. J Am Chem Soc (2009) 1.02

Aortic valve calcium score as a predictor for outcome after TAVI using the CoreValve revalving system. Int J Cardiol (2011) 0.99

Capsaicin infused into the PAG affects rat tail flick responses to noxious heat and alters neuronal firing in the RVM. J Neurophysiol (2003) 0.99

Myocardium: dynamic versus single-shot CT perfusion imaging. Radiology (2013) 0.99

Monomeric structures of the zymogen and active catalytic domain of complement protease c1r: further insights into the c1 activation mechanism. Structure (2002) 0.98

Key physiological differences in Candida albicans CDR1 induction by steroid hormones and antifungal drugs. Yeast (2006) 0.97

Expression of uncoupling protein-3 in subsarcolemmal and intermyofibrillar mitochondria of various mouse muscle types and its modulation by fasting. Eur J Biochem (2002) 0.97

Characterization of 7- and 19-month-old Tg2576 mice using multimodal in vivo imaging: limitations as a translatable model of Alzheimer's disease. Neurobiol Aging (2010) 0.96

Antifungal mechanisms supporting boric acid therapy of Candida vaginitis. J Antimicrob Chemother (2008) 0.96

Alzheimer's disease-like neuropathology of gene-targeted APP-SLxPS1mut mice expressing the amyloid precursor protein at endogenous levels. Neurobiol Dis (2005) 0.96

Splice variants of the beta-site APP-cleaving enzyme BACE1 in human brain and pancreas. Biochem Biophys Res Commun (2002) 0.96

Pulmonary vein electrophysiology during cryoballoon ablation as a predictor for procedural success. J Interv Card Electrophysiol (2011) 0.95

Monosodium iodoacetate-induced joint pain is associated with increased phosphorylation of mitogen activated protein kinases in the rat spinal cord. Mol Pain (2011) 0.95

A control study to evaluate a computer-based microarray experiment design recommendation system for gene-regulation pathways discovery. J Biomed Inform (2005) 0.94

Antisense knockdown of the rat alpha7 nicotinic acetylcholine receptor produces spatial memory impairment. Neurosci Lett (2006) 0.94

The novel calpain inhibitor A-705253 potently inhibits oligomeric beta-amyloid-induced dynamin 1 and tau cleavage in hippocampal neurons. Neurochem Int (2008) 0.93

Low frequency of deafness-associated GJB2 variants in Kenya and Sudan and novel GJB2 variants. Hum Mutat (2004) 0.93

Comparison of the first and second cryoballoon: high-volume single-center safety and efficacy analysis. Circ Arrhythm Electrophysiol (2014) 0.93

Role of left ventricular scar and Purkinje-like potentials during mapping and ablation of ventricular fibrillation in dilated cardiomyopathy. Pacing Clin Electrophysiol (2009) 0.92

Raman-spectroscopy-based noninvasive microanalysis of native lignin structure. Anal Bioanal Chem (2011) 0.92

Mice expressing the Swedish APP mutation on a 129 genetic background demonstrate consistent behavioral deficits and pathological markers of Alzheimer's disease. Brain Res (2009) 0.91

Alpha4beta2 nicotinic receptor stimulation contributes to the effects of nicotine in the DBA/2 mouse model of sensory gating. Psychopharmacology (Berl) (2006) 0.91

The antiepileptic drug levetiracetam selectively modifies kindling-induced alterations in gene expression in the temporal lobe of rats. Eur J Neurosci (2004) 0.91

Three-dimensional reconstruction allows accurate quantification and length measurements of coronary artery stenoses. EuroIntervention (2009) 0.91

Friction-based stabilization of juxtacellular recordings in freely moving rats. J Neurophysiol (2012) 0.91

A microflow cytometer exploited for the immunological differentiation of leukocytes. Cytometry A (2011) 0.91

LIM-only protein 4 interacts directly with the repulsive guidance molecule A receptor Neogenin. J Neurochem (2008) 0.90

A-85380: a pharmacological probe for the preclinical and clinical investigation of the alphabeta neuronal nicotinic acetylcholine receptor. CNS Drug Rev (2006) 0.90

In situ FT-IR microscopic study on enzymatic treatment of poplar wood cross-sections. Biomacromolecules (2008) 0.90

Selective delivery of secretory cargo in Golgi-derived carriers of nonepithelial cells. Traffic (2002) 0.90

Magnetic resonance imaging detection and time course of cerebral microhemorrhages during passive immunotherapy in living amyloid precursor protein transgenic mice. J Pharmacol Exp Ther (2010) 0.89

A high throughput fluorescent assay for measuring the activity of fatty acid amide hydrolase. J Neurosci Methods (2006) 0.89

Heterocomplex formation of 5-HT2A-mGlu2 and its relevance for cellular signaling cascades. Neuropharmacology (2012) 0.89

Micro-actuators: when artificial muscles made of nematic liquid crystal elastomers meet soft lithography. J Am Chem Soc (2006) 0.88

The vacuum chest wall lifter: an innovative, nonsurgical addition to the management of pectus excavatum. J Pediatr Surg (2005) 0.88

Differential diagnosis of bacterial infection and inflammatory response in kidney diseases using procalcitonin. J Nephrol (2002) 0.88

Microflow cytometers with integrated hydrodynamic focusing. Sensors (Basel) (2013) 0.88

Inhibitors of GlyT1 affect glycine transport via discrete binding sites. Mol Pharmacol (2008) 0.88

A double-blind, randomized, placebo/active controlled crossover evaluation of the efficacy and safety of Ritalin ® LA in children with attention-deficit/hyperactivity disorder in a laboratory classroom setting. J Child Adolesc Psychopharmacol (2010) 0.87

Nanosurfaces and nanostructures for artificial orthopedic implants. Nanomedicine (Lond) (2007) 0.87

Two-dimensional analysis of myocardial protein expression following myocardial ischemia and reperfusion in rabbits. Proteomics (2002) 0.87

Catecholamine-producing cells in the synovial tissue during arthritis: modulation of sympathetic neurotransmitters as new therapeutic target. Ann Rheum Dis (2010) 0.86

Chitin synthase III activity, but not the chitin ring, is required for remedial septa formation in budding yeast. FEMS Microbiol Lett (2003) 0.86

Preliminary evidence for altered motion tracking-based hyperactivity in ADHD siblings. Behav Brain Funct (2014) 0.86

Synthesis and SAR of highly potent dual 5-HT1A and 5-HT1B antagonists as potential antidepressant drugs. Bioorg Med Chem Lett (2005) 0.85

Melting of sodium clusters: where do the magic numbers come from? Phys Rev Lett (2005) 0.84

Serine protease inhibitor nafamostat given before reperfusion reduces inflammatory myocardial injury by complement and neutrophil inhibition. J Cardiovasc Pharmacol (2008) 0.84

Effects of the novel α7 nicotinic acetylcholine receptor agonist ABT-107 on sensory gating in DBA/2 mice: pharmacodynamic characterization. J Pharmacol Exp Ther (2012) 0.83

Characterization of the neuronal dopamine transporter DAT in human blood platelets. Neurosci Lett (2006) 0.83

Calpain inhibition prevents amyloid-beta-induced neurodegeneration and associated behavioral dysfunction in rats. Neuropharmacology (2010) 0.83

Extracellular BCL2 proteins are danger-associated molecular patterns that reduce tissue damage in murine models of ischemia-reperfusion injury. PLoS One (2010) 0.83

Formation of polymer vesicles by liquid crystal amphiphilic block copolymers. Langmuir (2006) 0.82

Blind image analysis for the compositional and structural characterization of plant cell walls. Anal Chim Acta (2011) 0.82

Disease burden of rotavirus gastroenteritis in children up to 5 years of age in two Swiss cantons: paediatrician- and hospital-based surveillance. Eur J Pediatr (2009) 0.81

Proteome analysis of myocardial tissue following ischemia and reperfusion--effects of complement inhibition. Biochim Biophys Acta (2006) 0.81

Targeting repulsive guidance molecule A to promote regeneration and neuroprotection in multiple sclerosis. Cell Rep (2015) 0.81