Published in J Biol Chem on August 31, 2005
Repair of topoisomerase I-mediated DNA damage. Prog Nucleic Acid Res Mol Biol (2006) 2.16
TDP1 facilitates chromosomal single-strand break repair in neurons and is neuroprotective in vivo. EMBO J (2007) 1.85
Poly(ADP-ribose) polymerase and XPF-ERCC1 participate in distinct pathways for the repair of topoisomerase I-induced DNA damage in mammalian cells. Nucleic Acids Res (2011) 1.76
Tyrosyl-DNA phosphodiesterase (Tdp1) participates in the repair of Top2-mediated DNA damage. Proc Natl Acad Sci U S A (2006) 1.70
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Tyrosyl-DNA phosphodiesterase as a target for anticancer therapy. Anticancer Agents Med Chem (2008) 1.43
Mus81-mediated DNA cleavage resolves replication forks stalled by topoisomerase I-DNA complexes. J Cell Biol (2011) 1.36
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Proteasome-dependent processing of topoisomerase I-DNA adducts into DNA double strand breaks at arrested replication forks. J Biol Chem (2009) 1.11
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SUMO modification of the neuroprotective protein TDP1 facilitates chromosomal single-strand break repair. Nat Commun (2012) 1.08
An RNA virus hijacks an incognito function of a DNA repair enzyme. Proc Natl Acad Sci U S A (2012) 1.08
TDP1 repairs nuclear and mitochondrial DNA damage induced by chain-terminating anticancer and antiviral nucleoside analogs. Nucleic Acids Res (2013) 1.08
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Increased expression and activity of repair genes TDP1 and XPF in non-small cell lung cancer. Lung Cancer (2006) 1.00
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A rapid and sensitive assay for DNA-protein covalent complexes in living cells. Nucleic Acids Res (2013) 0.98
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DNA repair factor MRE11/RAD50 cleaves 3'-phosphotyrosyl bonds and resects DNA to repair damage caused by topoisomerase 1 poisons. J Biol Chem (2011) 0.90
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TDP1 deficiency sensitizes human cells to base damage via distinct topoisomerase I and PARP mechanisms with potential applications for cancer therapy. Nucleic Acids Res (2013) 0.89
Tdp1 protects against oxidative DNA damage in non-dividing fission yeast. EMBO J (2009) 0.89
Topoisomerase I alone is sufficient to produce short DNA deletions and can also reverse nicks at ribonucleotide sites. J Biol Chem (2015) 0.88
Identification of novel DNA repair proteins via primary sequence, secondary structure, and homology. BMC Bioinformatics (2009) 0.87
AP endonuclease independent repair of abasic sites in Schizosaccharomyces pombe. Nucleic Acids Res (2011) 0.85
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Characterization of magnesium requirement of human 5'-tyrosyl DNA phosphodiesterase mediated reaction. BMC Res Notes (2012) 0.84
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Mitochondrial protein-linked DNA breaks perturb mitochondrial gene transcription and trigger free radical-induced DNA damage. Sci Adv (2017) 0.77
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Structure-function studies of a plant tyrosyl-DNA phosphodiesterase provide novel insights into DNA repair mechanisms of Arabidopsis thaliana. Biochem J (2012) 0.77
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Identification of novel PARP inhibitors using a cell-based TDP1 inhibitory assay in a quantitative high-throughput screening platform. DNA Repair (Amst) (2014) 0.75
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HTLV-1 bZIP factor suppresses TDP1 expression through inhibition of NRF-1 in adult T-cell leukemia. Sci Rep (2017) 0.75
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