Published in Bioinformatics on September 01, 2005
Discovering biological progression underlying microarray samples. PLoS Comput Biol (2011) 1.65
A general co-expression network-based approach to gene expression analysis: comparison and applications. BMC Syst Biol (2010) 1.63
Differential coexpression analysis of obesity-associated networks in human subcutaneous adipose tissue. Int J Obes (Lond) (2011) 0.94
A statistical framework for consolidating "sibling" probe sets for Affymetrix GeneChip data. BMC Genomics (2008) 0.94
Classification and biomarker identification using gene network modules and support vector machines. BMC Bioinformatics (2009) 0.90
New measurement methods of network robustness and response ability via microarray data. PLoS One (2013) 0.86
Integration of molecular network data reconstructs Gene Ontology. Bioinformatics (2014) 0.85
Clustering of High Throughput Gene Expression Data. Comput Oper Res (2012) 0.83
Global analysis of phase locking in gene expression during cell cycle: the potential in network modeling. BMC Syst Biol (2010) 0.82
Novel approach for coexpression analysis of E2F1-3 and MYC target genes in chronic myelogenous leukemia. Biomed Res Int (2014) 0.81
An effective method for network module extraction from microarray data. BMC Bioinformatics (2012) 0.81
Semi-supervised gene shaving method for predicting low variation biological pathways from genome-wide data. BMC Bioinformatics (2009) 0.78
Systematic identification of functional modules and cis-regulatory elements in Arabidopsis thaliana. BMC Bioinformatics (2011) 0.78
Multivariate Granger Causality Analysis of Obesity Related Variables. Austin Biom Biostat (2015) 0.75
Network inference through synergistic subnetwork evolution. EURASIP J Bioinform Syst Biol (2015) 0.75
An overview of bioinformatics methods for modeling biological pathways in yeast. Brief Funct Genomics (2015) 0.75
Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling. Nature (2009) 9.15
An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression. Cancer Cell (2010) 6.76
The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4. Nat Genet (2006) 5.36
Gene expression signatures diagnose influenza and other symptomatic respiratory viral infections in humans. Cell Host Microbe (2009) 4.55
CFH haplotypes without the Y402H coding variant show strong association with susceptibility to age-related macular degeneration. Nat Genet (2006) 4.51
Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration. Proc Natl Acad Sci U S A (2010) 4.30
In-frame deletion in a novel centrosomal/ciliary protein CEP290/NPHP6 perturbs its interaction with RPGR and results in early-onset retinal degeneration in the rd16 mouse. Hum Mol Genet (2006) 3.90
Seven new loci associated with age-related macular degeneration. Nat Genet (2013) 3.81
Nephrocystin-5, a ciliary IQ domain protein, is mutated in Senior-Loken syndrome and interacts with RPGR and calmodulin. Nat Genet (2005) 3.55
A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration. Proc Natl Acad Sci U S A (2007) 3.50
A common allele in RPGRIP1L is a modifier of retinal degeneration in ciliopathies. Nat Genet (2009) 3.36
E2-2 protein and Fuchs's corneal dystrophy. N Engl J Med (2010) 3.31
Targeting of GFP to newborn rods by Nrl promoter and temporal expression profiling of flow-sorted photoreceptors. Proc Natl Acad Sci U S A (2006) 3.27
High-resolution imaging with adaptive optics in patients with inherited retinal degeneration. Invest Ophthalmol Vis Sci (2007) 3.21
Strong association of the Y402H variant in complement factor H at 1q32 with susceptibility to age-related macular degeneration. Am J Hum Genet (2005) 3.19
Recruitment of the human TREX complex to mRNA during splicing. Genes Dev (2005) 3.13
Age-related macular degeneration: a high-resolution genome scan for susceptibility loci in a population enriched for late-stage disease. Am J Hum Genet (2004) 2.97
Cone-like morphological, molecular, and electrophysiological features of the photoreceptors of the Nrl knockout mouse. Invest Ophthalmol Vis Sci (2005) 2.51
CP110 suppresses primary cilia formation through its interaction with CEP290, a protein deficient in human ciliary disease. Dev Cell (2008) 2.35
Meta-analysis of genome scans of age-related macular degeneration. Hum Mol Genet (2005) 2.34
Toll-like receptor 4 variant D299G is associated with susceptibility to age-related macular degeneration. Hum Mol Genet (2005) 2.32
A comprehensive mutation analysis of RP2 and RPGR in a North American cohort of families with X-linked retinitis pigmentosa. Am J Hum Genet (2002) 2.29
TREX, SR proteins and export of mRNA. Curr Opin Cell Biol (2005) 2.19
Least biased target selection in probabilistic atlas construction. Med Image Comput Comput Assist Interv (2005) 2.14
Photoreceptor-specific nuclear receptor NR2E3 functions as a transcriptional activator in rod photoreceptors. Hum Mol Genet (2004) 2.14
Gene therapy rescues photoreceptor blindness in dogs and paves the way for treating human X-linked retinitis pigmentosa. Proc Natl Acad Sci U S A (2012) 2.12
Temporal dynamics of host molecular responses differentiate symptomatic and asymptomatic influenza a infection. PLoS Genet (2011) 2.10
Expression profiling of the developing and mature Nrl-/- mouse retina: identification of retinal disease candidates and transcriptional regulatory targets of Nrl. Hum Mol Genet (2004) 2.07
Photoreceptors of Nrl -/- mice coexpress functional S- and M-cone opsins having distinct inactivation mechanisms. J Gen Physiol (2005) 1.99
Fossil embryos from the Middle and Late Cambrian period of Hunan, south China. Nature (2004) 1.87
Cancer incidence among triazine herbicide manufacturing workers. J Occup Environ Med (2002) 1.84
Assessing the ecological security of the Tibetan plateau: methodology and a case study for Lhaze County. J Environ Manage (2005) 1.79
Mutation in a short-chain collagen gene, CTRP5, results in extracellular deposit formation in late-onset retinal degeneration: a genetic model for age-related macular degeneration. Hum Mol Genet (2003) 1.79
Transformation of cone precursors to functional rod photoreceptors by bZIP transcription factor NRL. Proc Natl Acad Sci U S A (2007) 1.74
Hypomorphic CEP290/NPHP6 mutations result in anosmia caused by the selective loss of G proteins in cilia of olfactory sensory neurons. Proc Natl Acad Sci U S A (2007) 1.74
Age-related macular degeneration: genetics and biology coming together. Annu Rev Genomics Hum Genet (2014) 1.69
RPGR-ORF15, which is mutated in retinitis pigmentosa, associates with SMC1, SMC3, and microtubule transport proteins. J Biol Chem (2005) 1.67
Centrosomal-ciliary gene CEP290/NPHP6 mutations result in blindness with unexpected sparing of photoreceptors and visual brain: implications for therapy of Leber congenital amaurosis. Hum Mutat (2007) 1.67
GRK1-dependent phosphorylation of S and M opsins and their binding to cone arrestin during cone phototransduction in the mouse retina. J Neurosci (2003) 1.66
Premature truncation of a novel protein, RD3, exhibiting subnuclear localization is associated with retinal degeneration. Am J Hum Genet (2006) 1.63
Longitudinal trends in use of bone mass measurement among older americans, 1999-2005. J Bone Miner Res (2008) 1.55
Mutations in a BTB-Kelch protein, KLHL7, cause autosomal-dominant retinitis pigmentosa. Am J Hum Genet (2009) 1.52
Early events in protein folding explored by rapid mixing methods. Chem Rev (2006) 1.50
In vivo function of the orphan nuclear receptor NR2E3 in establishing photoreceptor identity during mammalian retinal development. Hum Mol Genet (2006) 1.49
Structural comparison of metabolic networks in selected single cell organisms. BMC Bioinformatics (2005) 1.49
Effects of microgravity and hypergravity on platelet functions. Thromb Haemost (2009) 1.49
Mutations in RPGR and RP2 account for 15% of males with simplex retinal degenerative disease. Invest Ophthalmol Vis Sci (2012) 1.47
Benefit of adherence with bisphosphonates depends on age and fracture type: results from an analysis of 101,038 new bisphosphonate users. J Bone Miner Res (2008) 1.47
Prevalence and behavioral risk factors of overweight and obesity among children aged 2-18 in Beijing, China. Int J Pediatr Obes (2010) 1.46
A host-based RT-PCR gene expression signature to identify acute respiratory viral infection. Sci Transl Med (2013) 1.46
Mutation analysis of NR2E3 and NRL genes in Enhanced S Cone Syndrome. Hum Mutat (2004) 1.45
A comprehensive analysis of the expression of crystallins in mouse retina. Mol Vis (2003) 1.43
Recessive NRL mutations in patients with clumped pigmentary retinal degeneration and relative preservation of blue cone function. Proc Natl Acad Sci U S A (2004) 1.42
Biomarkers of cardiovascular disease as risk factors for age-related macular degeneration. Ophthalmology (2005) 1.41
Mortality among semiconductor and storage device-manufacturing workers. J Occup Environ Med (2005) 1.40
Identification of a rare coding variant in complement 3 associated with age-related macular degeneration. Nat Genet (2013) 1.39
Rod differentiation factor NRL activates the expression of nuclear receptor NR2E3 to suppress the development of cone photoreceptors. Brain Res (2008) 1.38
Microarray analysis of gene expression in the aging human retina. Invest Ophthalmol Vis Sci (2002) 1.38
A host transcriptional signature for presymptomatic detection of infection in humans exposed to influenza H1N1 or H3N2. PLoS One (2013) 1.37
Inner retinal abnormalities in X-linked retinitis pigmentosa with RPGR mutations. Invest Ophthalmol Vis Sci (2007) 1.37
A selective small molecule IkappaB Kinase beta inhibitor blocks nuclear factor kappaB-mediated inflammatory responses in human fibroblast-like synoviocytes, chondrocytes, and mast cells. J Pharmacol Exp Ther (2006) 1.36
Nuclear receptor NR2E3 gene mutations distort human retinal laminar architecture and cause an unusual degeneration. Hum Mol Genet (2004) 1.36
Associations of CFHR1-CFHR3 deletion and a CFH SNP to age-related macular degeneration are not independent. Nat Genet (2010) 1.35
Subunit dissociation and diffusion determine the subcellular localization of rod and cone transducins. J Neurosci (2007) 1.35
Barrier to autointegration factor interacts with the cone-rod homeobox and represses its transactivation function. J Biol Chem (2002) 1.34
Design of a switchable eliminase. Proc Natl Acad Sci U S A (2011) 1.34
Associations of six single nucleotide polymorphisms in obesity-related genes with BMI and risk of obesity in Chinese children. Diabetes (2010) 1.33
Mutations in TOPORS cause autosomal dominant retinitis pigmentosa with perivascular retinal pigment epithelium atrophy. Am J Hum Genet (2007) 1.33
Nucleic acid amplification tests for diagnosis of Neisseria gonorrhoeae and Chlamydia trachomatis rectal infections. J Clin Microbiol (2010) 1.33
Extraocular muscle morphogenesis and gene expression are regulated by Pitx2 gene dose. Invest Ophthalmol Vis Sci (2006) 1.33
Acute respiratory inflammation in children and black carbon in ambient air before and during the 2008 Beijing Olympics. Environ Health Perspect (2011) 1.32
Immunization with a single extracellular enveloped virus protein produced in bacteria provides partial protection from a lethal orthopoxvirus infection in a natural host. Virology (2005) 1.32
Recruitment of the rod pathway by cones in the absence of rods. J Neurosci (2004) 1.31
The common rs9939609 variant of the fat mass and obesity-associated gene is associated with obesity risk in children and adolescents of Beijing, China. BMC Med Genet (2010) 1.31
Improving the prediction of medication compliance: the example of bisphosphonates for osteoporosis. Med Care (2009) 1.31
Nrl-knockout mice deficient in Rpe65 fail to synthesize 11-cis retinal and cone outer segments. Invest Ophthalmol Vis Sci (2008) 1.31
Next-generation sequencing facilitates quantitative analysis of wild-type and Nrl(-/-) retinal transcriptomes. Mol Vis (2011) 1.29
De novo design of a single-chain diphenylporphyrin metalloprotein. J Am Chem Soc (2007) 1.28
Photoreceptor sensory cilia and ciliopathies: focus on CEP290, RPGR and their interacting proteins. Cilia (2012) 1.27
Cone photoreceptors are the main targets for gene therapy of NPHP5 (IQCB1) or NPHP6 (CEP290) blindness: generation of an all-cone Nphp6 hypomorph mouse that mimics the human retinal ciliopathy. Hum Mol Genet (2011) 1.27
Retinoid-related orphan nuclear receptor RORbeta is an early-acting factor in rod photoreceptor development. Proc Natl Acad Sci U S A (2009) 1.27
The evolution of Helicobacter pylori antibiotics resistance over 10 years in Beijing, China. Helicobacter (2010) 1.26
Nucleic acid amplification tests for diagnosis of Neisseria gonorrhoeae oropharyngeal infections. J Clin Microbiol (2009) 1.23
Exposure assessment for retrospective follow-up studies of semiconductor- and storage device-manufacturing workers. J Occup Environ Med (2005) 1.23
NMR-detected hydrogen exchange and molecular dynamics simulations provide structural insight into fibril formation of prion protein fragment 106-126. Proc Natl Acad Sci U S A (2003) 1.22
Candidate gene association study for diabetic retinopathy in persons with type 2 diabetes: the Candidate gene Association Resource (CARe). Invest Ophthalmol Vis Sci (2011) 1.22
Convergent incremental optimization transfer algorithms: application to tomography. IEEE Trans Med Imaging (2006) 1.20
The retinitis pigmentosa protein RP2 interacts with polycystin 2 and regulates cilia-mediated vertebrate development. Hum Mol Genet (2010) 1.20
Divalent metal transporter 1 (DMT1) regulation by Ndfip1 prevents metal toxicity in human neurons. Proc Natl Acad Sci U S A (2009) 1.20
Association of apolipoprotein E alleles with susceptibility to age-related macular degeneration in a large cohort from a single center. Invest Ophthalmol Vis Sci (2004) 1.19
Fourth Chinese National Consensus Report on the management of Helicobacter pylori infection. J Dig Dis (2013) 1.19