The kinase inhibitor imatinib mesylate inhibits TNF-{alpha} production in vitro and prevents TNF-dependent acute hepatic inflammation.

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Published in Proc Natl Acad Sci U S A on September 08, 2005

Authors

Anna Maria Wolf1, Dominik Wolf, Holger Rumpold, Susanne Ludwiczek, Barbara Enrich, Guenther Gastl, Guenter Weiss, Herbert Tilg

Author Affiliations

1: Department of Gastroenterology and Hepatology, Innsbruck Medical University, 6020 Innsbruck, Austria.

Associated clinical trials:

Trial of Imatinib for Hospitalized Adults With COVID-19 | NCT04394416

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