Published in Science on October 21, 2005
Planetary science. Titan clouds hint of heavy rains, methane gurglings. Science (2005) 1.59
The dynamics behind Titan's methane clouds. Proc Natl Acad Sci U S A (2006) 0.95
Global circulation as the main source of cloud activity on Titan. Nature (2009) 0.92
Storms in the tropics of Titan. Nature (2009) 0.90
Polar methane accumulation and rainstorms on Titan from simulations of the methane cycle. Nature (2012) 0.86
Dimming titan revealed by the Cassini observations. Sci Rep (2015) 0.75
Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial. J Clin Oncol (1997) 29.02
Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway. Cell (1996) 10.49
Some time-correlated reinforcement schedules and their effects on behavior. J Exp Anal Behav (1959) 6.80
Crow deaths as a sentinel surveillance system for West Nile virus in the northeastern United States, 1999. Emerg Infect Dis (2001) 5.83
Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis. J Clin Invest (1989) 5.71
Intestinal mucosal lesion in low-flow states. I. A morphological, hemodynamic, and metabolic reappraisal. Arch Surg (1970) 5.62
Effectiveness of bicycle helmets in preventing head injury in children: case-control study. BMJ (1994) 5.11
Targeting the E1 replication protein to the papillomavirus origin of replication by complex formation with the E2 transactivator. Science (1990) 4.92
The GAP-related domain of the neurofibromatosis type 1 gene product interacts with ras p21. Cell (1990) 4.84
Activation of BPV-1 replication in vitro by the transcription factor E2. Nature (1991) 4.51
Comparison of pharmacokinetics and systemic effects of inhaled fluticasone propionate in patients with asthma and healthy volunteers: a randomised crossover study. Lancet (2000) 4.22
Lymphatic mapping and sentinel node biopsy in the patient with breast cancer. JAMA (1996) 4.13
Insulin-regulatable tissues express a unique insulin-sensitive glucose transport protein. Nature (1988) 3.57
Nationalism and patriotism: national identification and out-group rejection. Br J Soc Psychol (2001) 3.33
Effect of oral nimodipine on cerebral infarction and outcome after subarachnoid haemorrhage: British aneurysm nimodipine trial. BMJ (1989) 3.32
Attenuation of isoproterenol-mediated vasodilatation in blacks. N Engl J Med (1995) 3.25
Cloning of a bcl-2 homologue by interaction with adenovirus E1B 19K. Nature (1995) 3.22
Somatic mutations in the neurofibromatosis 1 gene in human tumors. Cell (1992) 3.20
Solar disinfection of drinking water and diarrhoea in Maasai children: a controlled field trial. Lancet (1997) 3.20
Inactivation of the N-CAM gene in mice results in size reduction of the olfactory bulb and deficits in spatial learning. Nature (1994) 3.19
Biochemical activities of T-antigen proteins encoded by simian virus 40 A gene deletion mutants. Mol Cell Biol (1983) 3.06
Effects of teacher attention and a token reinforcement system in a junior high school special education class. Except Child (1970) 3.05
Prevalence of urethral Chlamydia trachomatis and Neisseria gonorrhoeae among asymptomatic, sexually active adolescent boys. J Infect Dis (1987) 3.02
Trauma care regionalization: a process-outcome evaluation. J Trauma (1999) 3.02
Conservation. Challenges to the future conservation of the Antarctic. Science (2012) 3.01
11beta-hydroxysteroid dehydrogenase type 1 knockout mice show attenuated glucocorticoid-inducible responses and resist hyperglycemia on obesity or stress. Proc Natl Acad Sci U S A (1997) 3.00
A full genome search in multiple sclerosis. Nat Genet (1996) 2.96
A prospective assessment of mortality in chronic spinal cord injury. Spinal Cord (2005) 2.96
Clinical aspects of X-linked hypohidrotic ectodermal dysplasia. Arch Dis Child (1987) 2.95
Reaction of endotoxin and surfactants. I. Physical and biological properties of endotoxin treated with sodium deoxycholate. J Bacteriol (1966) 2.86
Ipsilateral breast tumor recurrence postlumpectomy is predictive of subsequent mortality: results from a randomized trial. Investigators of the Ontario Clinical Oncology Group. Int J Radiat Oncol Biol Phys (1994) 2.86
Use of monoclonal antibodies as probes of simian virus 40 T antigen ATPase activity. J Biol Chem (1981) 2.77
Evaluation of readability and accuracy of information leaflets in general practice for patients with asthma. BMJ (1998) 2.75
Hepatic damage and death from overdose of paracetamol. Lancet (1973) 2.70
Assembly of herpes simplex virus type 1 capsids using a panel of recombinant baculoviruses. J Gen Virol (1994) 2.69
Cancer morbidity in rheumatoid arthritis. Ann Rheum Dis (1984) 2.67
Bcl-2 family proteins are essential for platelet survival. Cell Death Differ (2007) 2.67
Phyllosilicates on Mars and implications for early martian climate. Nature (2005) 2.66
Emerging trends in acquired neonatal intestinal disease: is it time to abandon Bell's criteria? J Perinatol (2007) 2.65
Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13. Nature (2002) 2.59
Measuring the activities of daily living: comparisons across national surveys. J Gerontol (1990) 2.56
Arrest of preterm labour and prolongation of gestation with glyceryl trinitrate, a nitric oxide donor. Lancet (1994) 2.53
An adenosine triphosphate-dependent stabilization of proteolytic activity in heterolysosomes. Evidence for a proton pump. Biochem J (1972) 2.51
Evidence for a polar ethane cloud on Titan. Science (2006) 2.50
Depression and mortality in nursing homes. JAMA (1991) 2.49
Trends in head injuries among child bicyclists. BMJ (1994) 2.47
Hand-held thoracic sonography for detecting post-traumatic pneumothoraces: the Extended Focused Assessment with Sonography for Trauma (EFAST). J Trauma (2004) 2.44
Ectopic induction of tendon and ligament in rats by growth and differentiation factors 5, 6, and 7, members of the TGF-beta gene family. J Clin Invest (1997) 2.42
Human N-ras: cDNA cloning and gene structure. Nucleic Acids Res (1985) 2.41
The glycoprotein encoded by the X-linked chronic granulomatous disease locus is a component of the neutrophil cytochrome b complex. Nature (1987) 2.38
Intestinal permeability in children with Crohn's disease and coeliac disease. Br Med J (Clin Res Ed) (1982) 2.36
An evaluation of the Gaspak system in the culture of anaerobic bacteria. J Appl Bacteriol (1972) 2.33
Molecular cloning and nucleic acid binding properties of the GAP-associated tyrosine phosphoprotein p62. Cell (1992) 2.32
Virus-specific IgG and IgM antibodies in normal and immunocompromised subjects infected with cytomegalovirus. J Infect Dis (1982) 2.29
West Nile virus surveillance in Connecticut in 2000: an intense epizootic without high risk for severe human disease. Emerg Infect Dis (2001) 2.26
Molecular cloning of a GTPase activating protein specific for the Krev-1 protein p21rap1. Cell (1991) 2.26
Quantitative studies of in vitro transformation by chemical carcinogens. J Natl Cancer Inst (1969) 2.26
Molecular cloning and expression of a G25K cDNA, the human homolog of the yeast cell cycle gene CDC42. Mol Cell Biol (1990) 2.25
Symptoms of depression and survival experience among three samples of smokers trying to quit. Psychol Addict Behav (2001) 2.20
Neonatal screening for inborn errors of metabolism: cost, yield and outcome. Health Technol Assess (1997) 2.20
Intracellular staining reveals different levels of stratification for on- and off-center ganglion cells in cat retina. J Neurophysiol (1978) 2.19
Reversal of drug resistance in human tumor xenografts by 2'-deoxy-5-azacytidine-induced demethylation of the hMLH1 gene promoter. Cancer Res (2000) 2.17
The perceived racism scale: a multidimensional assessment of the experience of white racism among African Americans. Ethn Dis (1996) 2.15
Conservation. High value and long life--double jeopardy for tunas and billfishes. Science (2011) 2.14
Intramuscular rocuronium in infants and children. Dose-ranging and tracheal intubating conditions. Anesthesiology (1996) 2.14
Human vascular permeability factor. Isolation from U937 cells. J Biol Chem (1989) 2.12
The Abbott IMx automated benchtop immunochemistry analyzer system. Clin Chem (1988) 2.12
Loss of bacterial diversity during antibiotic treatment of intubated patients colonized with Pseudomonas aeruginosa. J Clin Microbiol (2007) 2.12
Cause of death in rheumatoid arthritis. Br J Rheumatol (1984) 2.12
Inhibition of GTPase activating protein stimulation of Ras-p21 GTPase by the Krev-1 gene product. Science (1990) 2.09
GAP domains responsible for ras p21-dependent inhibition of muscarinic atrial K+ channel currents. Science (1992) 2.09
Insuring Latinos against the costs of illness. JAMA (1993) 2.09
Purified poloxamer 188 for treatment of acute vaso-occlusive crisis of sickle cell disease: A randomized controlled trial. JAMA (2001) 2.06
Space flight alters bacterial gene expression and virulence and reveals a role for global regulator Hfq. Proc Natl Acad Sci U S A (2007) 2.05
A pharmacodynamic explanation for the rapid onset/offset of rapacuronium bromide. Anesthesiology (1999) 2.03
Cisplatin and adriamycin resistance are associated with MutLalpha and mismatch repair deficiency in an ovarian tumor cell line. J Biol Chem (1996) 2.01
Second cancers following radiation treatment for cervical cancer. An international collaboration among cancer registries. J Natl Cancer Inst (1985) 2.00
Reconstitution of the Raf-1-MEK-ERK signal transduction pathway in vitro. Mol Cell Biol (1993) 1.99
New cosmid vectors developed for eukaryotic DNA cloning. Gene (1984) 1.97
Acute infectious epiglottitis in adults. Ann Intern Med (1969) 1.97
Multiple interactions control the intracellular localization of the herpes simplex virus type 1 capsid proteins. J Gen Virol (1996) 1.96
Characterization of a broadly expressed human leucocyte surface antigen MEM-43 anchored in membrane through phosphatidylinositol. Mol Immunol (1989) 1.94
Intestinal permeability in the newborn. Arch Dis Child (1984) 1.94
Training in international animal health. Vet Rec (2001) 1.93
Children and bicycles: what is really happening? Studies of fatal and non-fatal bicycle injury. Inj Prev (1995) 1.93