Published in Proc Natl Acad Sci U S A on November 17, 2005
Molecular imaging of lymphoid organs and immune activation by positron emission tomography with a new [18F]-labeled 2'-deoxycytidine analog. Nat Med (2008) 2.24
Monte Carlo simulations of absorbed dose in a mouse phantom from 18-fluorine compounds. Med Phys (2007) 1.39
Monitoring the efficacy of adoptively transferred prostate cancer-targeted human T lymphocytes with PET and bioluminescence imaging. J Nucl Med (2008) 1.35
Modulating metastasis by a lymphangiogenic switch in prostate cancer. Int J Cancer (2007) 1.30
Positron emission tomography with computed tomography imaging of neuroinflammation in experimental autoimmune encephalomyelitis. Proc Natl Acad Sci U S A (2007) 1.25
Positron emission tomography reporter genes and reporter probes: gene and cell therapy applications. Theranostics (2012) 1.19
Quantitative PET reporter gene imaging of CD8+ T cells specific for a melanoma-expressed self-antigen. Int Immunol (2008) 1.19
Structure-guided engineering of human thymidine kinase 2 as a positron emission tomography reporter gene for enhanced phosphorylation of non-natural thymidine analog reporter probe. J Biol Chem (2011) 1.10
Anti-tumor activity and trafficking of self, tumor-specific T cells against tumors located in the brain. Cancer Immunol Immunother (2008) 1.08
PET probes for distinct metabolic pathways have different cell specificities during immune responses in mice. J Clin Invest (2010) 1.00
Nuclear imaging of cancer cell therapies. J Nucl Med (2009) 0.92
Enhanced sensitivity to IL-2 signaling regulates the clinical responsiveness of IL-12-primed CD8(+) T cells in a melanoma model. J Immunol (2011) 0.91
Epidermal growth factor receptor antibody plus recombinant human endostatin in treatment of hepatic metastases after remnant gastric cancer resection. World J Gastroenterol (2007) 0.90
Targeted molecular imaging in oncology: focus on radiation therapy. Semin Radiat Oncol (2008) 0.89
Longitudinal, noninvasive imaging of T-cell effector function and proliferation in living subjects. Cancer Res (2010) 0.89
Noninvasive imaging of cell-mediated therapy for treatment of cancer. J Nucl Med (2008) 0.88
Noninvasive detection of tumor-infiltrating T cells by PET reporter imaging. J Clin Invest (2015) 0.83
Reporter gene imaging of immune responses to cancer: progress and challenges. Theranostics (2012) 0.83
Flow optimization study of a batch microfluidics PET tracer synthesizing device. Biomed Microdevices (2011) 0.82
Imaging aspects of the tumor stroma with therapeutic implications. Pharmacol Ther (2013) 0.81
Quantum mechanics/molecular mechanics investigation of the mechanism of phosphate transfer in human uridine-cytidine kinase 2. Org Biomol Chem (2009) 0.80
Non-invasive imaging of phosphoinositide-3-kinase-catalytic-subunit-alpha (PIK3CA) promoter modulation in small animal models. PLoS One (2013) 0.79
Use of nuclear magnetic resonance-based metabolomics in detecting drug resistance in cancer. Biomark Med (2009) 0.78
PET imaging to non-invasively study immune activation leading to antitumor responses with a 4-1BB agonistic antibody. J Immunother Cancer (2013) 0.77
Imaging virus-associated cancer. Curr Pharm Des (2008) 0.75
The current role of PET-CT in the characterization of hepatobiliary malignancies. HPB (Oxford) (2009) 0.75
New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst (2000) 133.74
Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors. Science (2002) 17.71
Molecular imaging of cancer with positron emission tomography. Nat Rev Cancer (2002) 7.79
The CD28 signaling pathway regulates glucose metabolism. Immunity (2002) 6.65
High-resolution 3D Bayesian image reconstruction using the microPET small-animal scanner. Phys Med Biol (1998) 5.47
Optical imaging of Renilla luciferase reporter gene expression in living mice. Proc Natl Acad Sci U S A (2001) 4.41
Lymphocyte trafficking and regional immunity. Adv Immunol (1999) 4.21
Intratumoral distribution of fluorine-18-fluorodeoxyglucose in vivo: high accumulation in macrophages and granulation tissues studied by microautoradiography. J Nucl Med (1992) 3.31
A mutant herpes simplex virus type 1 thymidine kinase reporter gene shows improved sensitivity for imaging reporter gene expression with positron emission tomography. Proc Natl Acad Sci U S A (2000) 3.28
Imaging tri-fusion multimodality reporter gene expression in living subjects. Cancer Res (2004) 3.16
Molecular control of immune/inflammatory responses: interactions between nuclear factor-kappa B and steroid receptor-signaling pathways. Endocr Rev (1999) 2.77
Anatomical loci of HIV-associated immune activation and association with viraemia. Lancet (2003) 2.19
Molecular imaging and cancer. Mol Cancer Ther (2003) 1.98
Serial in vivo imaging of the targeted migration of human HSV-TK-transduced antigen-specific lymphocytes. Nat Biotechnol (2003) 1.87
Induction and regression of primary moloney sarcoma virus-induced tumors in mice. Cancer Res (1967) 1.60
Quantitative imaging of the T cell antitumor response by positron-emission tomography. Proc Natl Acad Sci U S A (2003) 1.60
Molecular-genetic imaging: current and future perspectives. J Clin Invest (2003) 1.49
Differential kinetics of antigen-specific CD4+ and CD8+ T cell responses in the regression of retrovirus-induced sarcomas. J Immunol (2002) 1.46
Molecular imaging of gene therapy for cancer. Gene Ther (2004) 1.28
Quantitation of cell number by a positron emission tomography reporter gene strategy. Mol Imaging Biol (2004) 1.26
Multimodality imaging of lymphocytic migration using lentiviral-based transduction of a tri-fusion reporter gene. Mol Imaging Biol (2004) 1.23
PET imaging of brain macrophages using the peripheral benzodiazepine receptor in a macaque model of neuroAIDS. J Clin Invest (2004) 1.15
Acute regulation of glucose transport in a monocyte-macrophage cell line: Glut-3 affinity for glucose is enhanced during the respiratory burst. Biochem J (1997) 1.14
Imaging of delayed-type hypersensitivity reaction by PET and 18F-galacto-RGD. J Nucl Med (2005) 1.03
Molecular imaging applications for immunology. Clin Immunol (2004) 1.02
Searching for hematopoietic stem cells. II. The heterogeneity of Thy-1.1(lo)Lin(-/lo)Sca-1+ mouse hematopoietic stem cells separated by counterflow centrifugal elutriation. Exp Hematol (1996) 0.88
Differential uptake of (18)F-fluorodeoxyglucose by experimental tumors xenografted into immunocompetent and immunodeficient mice and the effect of immunomodification. Neoplasia (2003) 0.88
Cell-mediated immunity to Moloney sarcoma virus in mice. II. Analysis of antigenic specificities involved in T lymphocyte-mediated in vivo rejection of murine sarcoma virus-induced tumors. Eur J Immunol (1975) 0.83
The developing role of cytokines for imaging inflammation and infection. Cytokine (2000) 0.82
Visualizing T cell migration in vivo. Int Arch Allergy Immunol (2003) 0.81
Molecular imaging in living subjects: seeing fundamental biological processes in a new light. Genes Dev (2003) 11.29
Carbon nanotubes as photoacoustic molecular imaging agents in living mice. Nat Nanotechnol (2008) 6.41
Identification of a cell of origin for human prostate cancer. Science (2010) 6.33
Peptide-labeled near-infrared quantum dots for imaging tumor vasculature in living subjects. Nano Lett (2006) 5.63
A brain tumor molecular imaging strategy using a new triple-modality MRI-photoacoustic-Raman nanoparticle. Nat Med (2012) 4.64
Self-illuminating quantum dot conjugates for in vivo imaging. Nat Biotechnol (2006) 4.60
Isolation and functional characterization of murine prostate stem cells. Proc Natl Acad Sci U S A (2006) 4.54
In vivo visualization of embryonic stem cell survival, proliferation, and migration after cardiac delivery. Circulation (2006) 4.48
A pilot toxicology study of single-walled carbon nanotubes in a small sample of mice. Nat Nanotechnol (2008) 4.43
The Sca-1 cell surface marker enriches for a prostate-regenerating cell subpopulation that can initiate prostate tumorigenesis. Proc Natl Acad Sci U S A (2005) 4.12
Molecular imaging in drug development. Nat Rev Drug Discov (2008) 4.06
Matrix-insensitive protein assays push the limits of biosensors in medicine. Nat Med (2009) 3.58
Bmi-1 is a crucial regulator of prostate stem cell self-renewal and malignant transformation. Cell Stem Cell (2010) 3.41
Pten deletion leads to the expansion of a prostatic stem/progenitor cell subpopulation and tumor initiation. Proc Natl Acad Sci U S A (2006) 3.34
Nanoparticle PEGylation for imaging and therapy. Nanomedicine (Lond) (2011) 3.33
Trop2 identifies a subpopulation of murine and human prostate basal cells with stem cell characteristics. Proc Natl Acad Sci U S A (2008) 3.26
In vivo regeneration of murine prostate from dissociated cell populations of postnatal epithelia and urogenital sinus mesenchyme. Proc Natl Acad Sci U S A (2003) 3.19
Imaging tri-fusion multimodality reporter gene expression in living subjects. Cancer Res (2004) 3.16
US imaging of tumor angiogenesis with microbubbles targeted to vascular endothelial growth factor receptor type 2 in mice. Radiology (2008) 3.15
The BCR-ABL story: bench to bedside and back. Annu Rev Immunol (2004) 3.00
microPET imaging of glioma integrin {alpha}v{beta}3 expression using (64)Cu-labeled tetrameric RGD peptide. J Nucl Med (2005) 2.96
ETS family transcription factors collaborate with alternative signaling pathways to induce carcinoma from adult murine prostate cells. Proc Natl Acad Sci U S A (2009) 2.93
Dual-function probe for PET and near-infrared fluorescence imaging of tumor vasculature. J Nucl Med (2007) 2.86
Transcriptional and functional profiling of human embryonic stem cell-derived cardiomyocytes. PLoS One (2008) 2.85
Multistep synthesis of a radiolabeled imaging probe using integrated microfluidics. Science (2005) 2.83
A molecular imaging primer: modalities, imaging agents, and applications. Physiol Rev (2012) 2.76
microPET-based biodistribution of quantum dots in living mice. J Nucl Med (2007) 2.76
Multiplexed imaging of surface enhanced Raman scattering nanotags in living mice using noninvasive Raman spectroscopy. Proc Natl Acad Sci U S A (2009) 2.71
Basal epithelial stem cells are efficient targets for prostate cancer initiation. Proc Natl Acad Sci U S A (2010) 2.69
Quantitative PET imaging of tumor integrin alphavbeta3 expression with 18F-FRGD2. J Nucl Med (2006) 2.65
Noninvasive detection of therapeutic cytolytic T cells with 18F-FHBG PET in a patient with glioma. Nat Clin Pract Oncol (2008) 2.61
Particle size, surface coating, and PEGylation influence the biodistribution of quantum dots in living mice. Small (2009) 2.59
The AMPK agonist AICAR inhibits the growth of EGFRvIII-expressing glioblastomas by inhibiting lipogenesis. Proc Natl Acad Sci U S A (2009) 2.55
A clinical microchip for evaluation of single immune cells reveals high functional heterogeneity in phenotypically similar T cells. Nat Med (2011) 2.54
Self-renewal and multilineage differentiation in vitro from murine prostate stem cells. Stem Cells (2007) 2.50
124I-labeled engineered anti-CEA minibodies and diabodies allow high-contrast, antigen-specific small-animal PET imaging of xenografts in athymic mice. J Nucl Med (2003) 2.44
DNA-encoded antibody libraries: a unified platform for multiplexed cell sorting and detection of genes and proteins. J Am Chem Soc (2007) 2.42
Molecular imaging of cardiac cell transplantation in living animals using optical bioluminescence and positron emission tomography. Circulation (2003) 2.37
Molecular optical imaging with radioactive probes. PLoS One (2010) 2.36
Optical bioluminescence and positron emission tomography imaging of a novel fusion reporter gene in tumor xenografts of living mice. Cancer Res (2003) 2.36
Antiangiogenic cancer therapy: monitoring with molecular US and a clinically translatable contrast agent (BR55). Radiology (2010) 2.32
NKX3.1 stabilizes p53, inhibits AKT activation, and blocks prostate cancer initiation caused by PTEN loss. Cancer Cell (2006) 2.29
PET imaging of colorectal cancer in xenograft-bearing mice by use of an 18F-labeled T84.66 anti-carcinoembryonic antigen diabody. J Nucl Med (2007) 2.28
Noninvasive cell-tracking methods. Nat Rev Clin Oncol (2011) 2.26
Molecular imaging of lymphoid organs and immune activation by positron emission tomography with a new [18F]-labeled 2'-deoxycytidine analog. Nat Med (2008) 2.24
Differentiation, survival, and function of embryonic stem cell derived endothelial cells for ischemic heart disease. Circulation (2007) 2.21
PET of vascular endothelial growth factor receptor expression. J Nucl Med (2006) 2.18
Enhanced paracrine FGF10 expression promotes formation of multifocal prostate adenocarcinoma and an increase in epithelial androgen receptor. Cancer Cell (2007) 2.14
Mathematical model identifies blood biomarker-based early cancer detection strategies and limitations. Sci Transl Med (2011) 2.07
Isolation, cultivation and characterization of adult murine prostate stem cells. Nat Protoc (2010) 1.96
Endothelial cells derived from human iPSCS increase capillary density and improve perfusion in a mouse model of peripheral arterial disease. Arterioscler Thromb Vasc Biol (2011) 1.93
Progression of prostate cancer by synergy of AKT with genotropic and nongenotropic actions of the androgen receptor. Proc Natl Acad Sci U S A (2006) 1.93
Tailoring the pharmacokinetics and positron emission tomography imaging properties of anti-carcinoembryonic antigen single-chain Fv-Fc antibody fragments. Cancer Res (2005) 1.88
Dual-targeted contrast agent for US assessment of tumor angiogenesis in vivo. Radiology (2008) 1.88
Targeted microbubbles for imaging tumor angiogenesis: assessment of whole-body biodistribution with dynamic micro-PET in mice. Radiology (2008) 1.88
Selective regulation of lymphopoiesis and leukemogenesis by individual zinc fingers of Ikaros. Nat Immunol (2013) 1.88
Visualization of advanced human prostate cancer lesions in living mice by a targeted gene transfer vector and optical imaging. Nat Med (2002) 1.86
FDG-PET and beyond: molecular breast cancer imaging. J Clin Oncol (2005) 1.86
How molecular imaging is speeding up antiangiogenic drug development. Mol Cancer Ther (2006) 1.81
An inhibitor of nonhomologous end-joining abrogates double-strand break repair and impedes cancer progression. Cell (2012) 1.81
Aging and cancer resistance in lymphoid progenitors are linked processes conferred by p16Ink4a and Arf. Genes Dev (2008) 1.79
Quantum dot imaging for embryonic stem cells. BMC Biotechnol (2007) 1.78
Human prostate sphere-forming cells represent a subset of basal epithelial cells capable of glandular regeneration in vivo. Prostate (2010) 1.78
Glia-dependent TGF-beta signaling, acting independently of the TH17 pathway, is critical for initiation of murine autoimmune encephalomyelitis. J Clin Invest (2007) 1.78
Differential transformation capacity of Src family kinases during the initiation of prostate cancer. Proc Natl Acad Sci U S A (2011) 1.76
Stem cells in prostate cancer initiation and progression. J Clin Invest (2007) 1.76
Migration to apoptotic "find-me" signals is mediated via the phagocyte receptor G2A. J Biol Chem (2007) 1.75
Positron emission tomography imaging of adenoviral-mediated transgene expression in liver cancer patients. Gastroenterology (2005) 1.75
Collagen matrices enhance survival of transplanted cardiomyoblasts and contribute to functional improvement of ischemic rat hearts. Circulation (2006) 1.75
Microfluidic single-cell analysis shows that porcine induced pluripotent stem cell-derived endothelial cells improve myocardial function by paracrine activation. Circ Res (2012) 1.74
Optical imaging of cardiac reporter gene expression in living rats. Circulation (2002) 1.69
Multifunctional T-cell analyses to study response and progression in adoptive cell transfer immunotherapy. Cancer Discov (2013) 1.68
Meta-analysis of the performance of (18)F-FDG PET in cutaneous melanoma. Eur J Nucl Med Mol Imaging (2009) 1.64
Functional and transcriptional characterization of human embryonic stem cell-derived endothelial cells for treatment of myocardial infarction. PLoS One (2009) 1.64
Multimodality imaging of tumor xenografts and metastases in mice with combined small-animal PET, small-animal CT, and bioluminescence imaging. J Nucl Med (2007) 1.63
Antitumor activity from antigen-specific CD8 T cells generated in vivo from genetically engineered human hematopoietic stem cells. Proc Natl Acad Sci U S A (2011) 1.61
Gene expression tomography. Physiol Genomics (2002) 1.61
Nanooncology: the future of cancer diagnosis and therapy. CA Cancer J Clin (2013) 1.61
Tetraphenylphosphonium as a novel molecular probe for imaging tumors. J Nucl Med (2004) 1.60
Treatment of metastatic melanoma with an orally available inhibitor of the Ras-Raf-MAPK cascade. Cancer Res (2003) 1.60
N-cadherin-catenin complexes form prior to cleavage of the proregion and transport to the plasma membrane. J Biol Chem (2003) 1.60
Quantitative imaging of the T cell antitumor response by positron-emission tomography. Proc Natl Acad Sci U S A (2003) 1.60
Pilot pharmacokinetic and dosimetric studies of (18)F-FPPRGD2: a PET radiopharmaceutical agent for imaging α(v)β(3) integrin levels. Radiology (2011) 1.59
Trafficking mesenchymal stem cell engraftment and differentiation in tumor-bearing mice by bioluminescence imaging. Stem Cells (2009) 1.58
PET imaging of herpes simplex virus type 1 thymidine kinase (HSV1-tk) or mutant HSV1-sr39tk reporter gene expression in mice and humans using [18F]FHBG. Nat Protoc (2006) 1.57
Molecular imaging of drug-modulated protein-protein interactions in living subjects. Cancer Res (2004) 1.55
Fluorescent magnetic nanoparticles for magnetically enhanced cancer imaging and targeting in living subjects. ACS Nano (2012) 1.55
Laryngeal cancer: diagnosis and preoperative work-up. Otolaryngol Clin North Am (2008) 1.55
Optimizing radiolabeled engineered anti-p185HER2 antibody fragments for in vivo imaging. Cancer Res (2005) 1.54
Role of autonomous androgen receptor signaling in prostate cancer initiation is dichotomous and depends on the oncogenic signal. Proc Natl Acad Sci U S A (2011) 1.53
A new link between the c-Abl tyrosine kinase and phosphoinositide signalling through PLC-gamma1. Nat Cell Biol (2003) 1.53
Effects of epigenetic modulation on reporter gene expression: implications for stem cell imaging. FASEB J (2005) 1.52
18F-FDG uptake in lung, breast, and colon cancers: molecular biology correlates and disease characterization. J Nucl Med (2009) 1.52
Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia. 1993. J Immunol (2012) 1.51