Published in Diabetes on January 01, 2006
Interleukin 7 signaling in dendritic cells regulates the homeostatic proliferation and niche size of CD4+ T cells. Nat Immunol (2009) 1.98
Regulatory T-cells and immune tolerance in pregnancy: a new target for infertility treatment? Hum Reprod Update (2009) 1.43
Pathogenic T cells have a paradoxical protective effect in murine autoimmune diabetes by boosting Tregs. J Clin Invest (2010) 1.40
The influence of IL-2 family cytokines on activation and function of naturally occurring regulatory T cells. J Leukoc Biol (2008) 1.26
Resting regulatory CD4 T cells: a site of HIV persistence in patients on long-term effective antiretroviral therapy. PLoS One (2008) 1.21
SHIP limits immunoregulatory capacity in the T-cell compartment. Blood (2009) 1.15
Combination of rapamycin and IL-2 increases de novo induction of human CD4(+)CD25(+)FOXP3(+) T cells. J Autoimmun (2008) 1.14
Resolving the conundrum of islet transplantation by linking metabolic dysregulation, inflammation, and immune regulation. Endocr Rev (2008) 1.12
A microsphere-based vaccine prevents and reverses new-onset autoimmune diabetes. Diabetes (2008) 1.01
Regulatory T cells and toll-like receptors: regulating the regulators. Ann Rheum Dis (2007) 0.99
Current state of type 1 diabetes immunotherapy: incremental advances, huge leaps, or more of the same? Clin Dev Immunol (2011) 0.92
Interleukin-7 influences FOXP3+CD4+ regulatory T cells peripheral homeostasis. PLoS One (2012) 0.92
Children with islet autoimmunity and enterovirus infection demonstrate a distinct cytokine profile. Diabetes (2012) 0.90
An in vivo IL-7 requirement for peripheral Foxp3+ regulatory T cell homeostasis. J Immunol (2012) 0.89
Nonviral-mediated hepatic expression of IGF-I increases Treg levels and suppresses autoimmune diabetes in mice. Diabetes (2012) 0.89
Multifunctional dendritic cell-targeting polymeric microparticles: engineering new vaccines for type 1 diabetes. Hum Vaccin (2011) 0.89
Modulation of the maternal immune system by the pre-implantation embryo. BMC Genomics (2010) 0.88
Regulatory T cells and Atherosclerosis. J Clin Exp Cardiolog (2012) 0.85
The immunotherapeutic potential of dendritic cells in type 1 diabetes. Clin Exp Immunol (2010) 0.84
Interleukin-7 matures suppressive CD127(+) forkhead box P3 (FoxP3)(+) T cells into CD127(-) CD25(high) FoxP3(+) regulatory T cells. Clin Exp Immunol (2011) 0.84
Inhibition of suppressive T cell factor 1 (TCF-1) isoforms in naive CD4+ T cells is mediated by IL-4/STAT6 signaling. J Biol Chem (2010) 0.84
Pre-existing autoimmunity determines type 1 diabetes outcome after Flt3-ligand treatment. J Autoimmun (2009) 0.84
CD2-mediated regulation of peripheral CD4(+) CD25(+) regulatory T-cell apoptosis accompanied by down-regulation of Bim. Immunology (2013) 0.81
Involvement of suppressive B-lymphocytes in the mechanism of tolerogenic dendritic cell reversal of type 1 diabetes in NOD mice. PLoS One (2014) 0.81
Differential response of regulatory and conventional CD4⁺ lymphocytes to CD3 engagement: clues to a possible mechanism of anti-CD3 action? J Immunol (2013) 0.80
Decreased microRNA miR-181c expression in peripheral blood mononuclear cells correlates with elevated serum levels of IL-7 and IL-17 in patients with myasthenia gravis. Clin Exp Med (2015) 0.76
Autoimmunity in Coxsackievirus B3 induced myocarditis: role of estrogen in suppressing autoimmunity. Future Virol (2010) 0.76
The modulation of enzyme indoleamine 2,3-dioxygenase from dendritic cells for the treatment of type 1 diabetes mellitus. Drug Des Devel Ther (2017) 0.75
Tolerogenic immunosuppression for organ transplantation. Lancet (2003) 4.09
Production of alpha 1,3-galactosyltransferase-deficient pigs. Science (2002) 3.96
On the use of general control samples for genome-wide association studies: genetic matching highlights causal variants. Am J Hum Genet (2008) 3.95
Screen and clean: a tool for identifying interactions in genome-wide association studies. Genet Epidemiol (2010) 2.70
A new Hu-PBL model for the study of human islet alloreactivity based on NOD-scid mice bearing a targeted mutation in the IL-2 receptor gamma chain gene. Clin Immunol (2007) 2.23
Response of human islets to isolation stress and the effect of antioxidant treatment. Diabetes (2004) 2.16
Factors associated with islet yield and insulin independence after total pancreatectomy and islet cell autotransplantation in patients with chronic pancreatitis utilizing off-site islet isolation: Cleveland Clinic experience. J Clin Endocrinol Metab (2015) 2.14
Clinical xenotransplantation: the next medical revolution? Lancet (2011) 1.84
Thymus-specific deletion of insulin induces autoimmune diabetes. EMBO J (2009) 1.70
Liver-specific deletion of the growth hormone receptor reveals essential role of growth hormone signaling in hepatic lipid metabolism. J Biol Chem (2009) 1.69
Phase I (safety) study of autologous tolerogenic dendritic cells in type 1 diabetic patients. Diabetes Care (2011) 1.65
Cytoplasmic islet cell antibodies remain valuable in defining risk of progression to type 1 diabetes in subjects with other islet autoantibodies. Pediatr Diabetes (2005) 1.64
Monocytes are progressively activated in the circulation of pregnant women. J Leukoc Biol (2002) 1.63
HLA-A*0201-restricted T cells from humanized NOD mice recognize autoantigens of potential clinical relevance to type 1 diabetes. J Immunol (2006) 1.58
Toward a cure for type 1 diabetes mellitus: diabetes-suppressive dendritic cells and beyond. Pediatr Diabetes (2008) 1.50
Functionally important glycosyltransferase gain and loss during catarrhine primate emergence. Proc Natl Acad Sci U S A (2006) 1.46
Widespread and stable pancreatic gene transfer by adeno-associated virus vectors via different routes. Diabetes (2006) 1.45
Identification of novel IGRP epitopes targeted in type 1 diabetes patients. Clin Immunol (2008) 1.38
Gene transfer of constitutively active Akt markedly improves human islet transplant outcomes in diabetic severe combined immunodeficient mice. Diabetes (2005) 1.27
Clinical islet xenotransplantation: how close are we? Diabetes (2012) 1.26
Prospective and challenges of islet transplantation for the therapy of autoimmune diabetes. Pancreas (2006) 1.25
An extensive genetic program occurring during postnatal growth in multiple tissues. Endocrinology (2008) 1.24
Indoleamine 2,3-dioxygenase expression in transplanted NOD Islets prolongs graft survival after adoptive transfer of diabetogenic splenocytes. Diabetes (2002) 1.23
FoxO1 links insulin resistance to proinflammatory cytokine IL-1beta production in macrophages. Diabetes (2009) 1.22
Reactive oxygen species production by forward and reverse electron fluxes in the mitochondrial respiratory chain. PLoS Comput Biol (2011) 1.21
Disruption of innate-mediated proinflammatory cytokine and reactive oxygen species third signal leads to antigen-specific hyporesponsiveness. J Immunol (2007) 1.19
Molecular basis of evolutionary loss of the alpha 1,3-galactosyltransferase gene in higher primates. J Biol Chem (2001) 1.18
Preservation of human islet cell functional mass by anti-oxidative action of a novel SOD mimic compound. Diabetes (2002) 1.17
Human proinsulin C-peptide reduces high glucose-induced proliferation and NF-kappaB activation in vascular smooth muscle cells. Atherosclerosis (2008) 1.17
Antisense oligonucleotides down-regulating costimulation confer diabetes-preventive properties to nonobese diabetic mouse dendritic cells. J Immunol (2004) 1.16
Prevention of diabetes in NOD mice by administration of dendritic cells deficient in nuclear transcription factor-kappaB activity. Diabetes (2003) 1.15
The role of external and matrix pH in mitochondrial reactive oxygen species generation. J Biol Chem (2008) 1.13
Protection of islets by in situ peptide-mediated transduction of the Ikappa B kinase inhibitor Nemo-binding domain peptide. J Biol Chem (2003) 1.12
Using ancestry matching to combine family-based and unrelated samples for genome-wide association studies. Stat Med (2010) 1.11
Hepatocyte growth factor modulates interleukin-6 production in bone marrow derived macrophages: implications for inflammatory mediated diseases. PLoS One (2010) 1.10
Bistability of mitochondrial respiration underlies paradoxical reactive oxygen species generation induced by anoxia. PLoS Comput Biol (2009) 1.10
Footer: a quantitative comparative genomics method for efficient recognition of cis-regulatory elements. Genome Res (2005) 1.09
Gene transfer of manganese superoxide dismutase extends islet graft function in a mouse model of autoimmune diabetes. Diabetes (2003) 1.08
Immunosuppressive effects of glucosamine. J Biol Chem (2002) 1.08
Recovery of the endogenous beta cell function in the NOD model of autoimmune diabetes. Stem Cells (2003) 1.07
Suppression of autoimmune diabetes by soluble galectin-1. J Immunol (2009) 1.06
Quantification of CpG island methylation in progressive breast lesions from normal to invasive carcinoma. Cancer Lett (2007) 1.05
FoxO6 integrates insulin signaling with gluconeogenesis in the liver. Diabetes (2011) 1.03
Isolation outcome and functional characteristics of young and adult pig pancreatic islets for transplantation studies. Xenotransplantation (2007) 1.02
Body window-enabled in vivo multicolor imaging of transplanted mouse islets expressing an insulin-Timer fusion protein. Biotechniques (2003) 1.02
Harmful delayed effects of exogenous isolation enzymes on isolated human islets: relevance to clinical transplantation. Am J Transplant (2005) 1.01
A microsphere-based vaccine prevents and reverses new-onset autoimmune diabetes. Diabetes (2008) 1.01
Reduction of early graft loss after intraportal porcine islet transplantation in monkeys. Transplantation (2007) 0.99
Redox modulation protects islets from transplant-related injury. Diabetes (2010) 0.98
Dendritic cells expressing transgenic galectin-1 delay onset of autoimmune diabetes in mice. J Immunol (2006) 0.98
Phagocytosis of enterovirus-infected pancreatic beta-cells triggers innate immune responses in human dendritic cells. Diabetes (2010) 0.97
Retaining antibodies in tumors with a self-assembling injectable system. Mol Pharm (2013) 0.96
Induction of diabetes in cynomolgus monkeys with high-dose streptozotocin: adverse effects and early responses. Pancreas (2006) 0.95
Lessons of organ-induced tolerance learned from historical clinical experience. Transplantation (2004) 0.94
The potential of genetically-engineered pigs in providing an alternative source of organs and cells for transplantation. J Biomed Res (2013) 0.93
AAV8-mediated gene transfer of interleukin-4 to endogenous beta-cells prevents the onset of diabetes in NOD mice. Mol Ther (2008) 0.93
Humoral autoimmunity against the extracellular domain of the neuroendocrine autoantigen IA-2 heightens the risk of type 1 diabetes. Endocrinology (2010) 0.92
Recovery of endogenous beta-cell function in nonhuman primates after chemical diabetes induction and islet transplantation. Diabetes (2008) 0.92
Current state of type 1 diabetes immunotherapy: incremental advances, huge leaps, or more of the same? Clin Dev Immunol (2011) 0.92
Facilitating physiologic self-regeneration: a step beyond islet cell replacement. Pharm Res (2006) 0.92
Multifaceted therapeutic approaches for a multigenic disease. Diabetes (2005) 0.91
Early islet damage after direct exposure of pig islets to blood: has humoral immunity been underestimated? Cell Transplant (2012) 0.91
Gene combination transfer to block autoimmune damage in transplanted islets of Langerhans. Exp Diabesity Res (2004) 0.89
Four-color flow cytometric analysis of peripheral blood donor cell chimerism. Hum Immunol (2003) 0.89
Proteomic analysis of fructose-induced fatty liver in hamsters. Metabolism (2008) 0.89
FOXO1 mediates the autocrine effect of endothelin-1 on endothelial cell survival. Mol Endocrinol (2012) 0.88
Increased Expression of Monocyte CD11b (Mac-1) in Overweight Recent-Onset Type 1 Diabetic Children. Rev Diabet Stud (2007) 0.88
Development of new-generation HU-PBMC-NOD/SCID mice to study human islet alloreactivity. Ann N Y Acad Sci (2007) 0.87
Pyrosequencing-based strategies for improved allele typing of human leukocyte antigen loci. Methods Mol Biol (2007) 0.87
Cytokine and chemokine production by human pancreatic islets upon enterovirus infection. Diabetes (2012) 0.87
Multistationary and oscillatory modes of free radicals generation by the mitochondrial respiratory chain revealed by a bifurcation analysis. PLoS Comput Biol (2012) 0.87
Antidiabetic sulfonylurea stimulates insulin secretion independently of plasma membrane KATP channels. Am J Physiol Endocrinol Metab (2007) 0.87
Indoleamine 2,3-dioxygenase gene transfer prolongs cardiac allograft survival. Am J Physiol Heart Circ Physiol (2007) 0.86
Toward clinical islet xenotransplantation - are revisions to the IXA guidelines warranted? Xenotransplantation (2013) 0.86
Pig-to-nonhuman primates pancreatic islet xenotransplantation: an overview. Curr Diab Rep (2011) 0.86
Rehabilitation of adaptive immunity and regeneration of beta cells. Trends Biotechnol (2006) 0.86
Dendritic cell mediated therapy for immunoregulation of type 1 diabetes mellitus. Pediatr Endocrinol Rev (2008) 0.86
Identification of a cardiac specific protein transduction domain by in vivo biopanning using a M13 phage peptide display library in mice. PLoS One (2010) 0.85
It's time to bring dendritic cell therapy to type 1 diabetes. Diabetes (2014) 0.85
Y Chromosomal Sequences Identified in Gonadal Tissue of Two 45,X Patients with Turner Syndrome. Endocr Pathol (1995) 0.85
Induction of immune tolerance to facilitate beta cell regeneration in type 1 diabetes. Adv Drug Deliv Rev (2007) 0.85