Published in Biofactors on January 01, 2005
Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling. Biochem J (2012) 3.37
Differentiation of SH-SY5Y cells to a neuronal phenotype changes cellular bioenergetics and the response to oxidative stress. Free Radic Biol Med (2011) 1.25
The Role of Autophagy, Mitophagy and Lysosomal Functions in Modulating Bioenergetics and Survival in the Context of Redox and Proteotoxic Damage: Implications for Neurodegenerative Diseases. Aging Dis (2016) 0.79
Protein Phosphatase 2A Mediates Oxidative Stress Induced Apoptosis in Osteoblasts. Mediators Inflamm (2015) 0.79
Peroxiredoxins. Biol Chem (2002) 3.61
Voltage-dependent anion channels control the release of the superoxide anion from mitochondria to cytosol. J Biol Chem (2002) 2.94
Green tea polyphenols block the anticancer effects of bortezomib and other boronic acid-based proteasome inhibitors. Blood (2009) 2.61
Gene disruption discloses role of selenoprotein P in selenium delivery to target tissues. Biochem J (2003) 2.30
The proteasomal system. Mol Aspects Med (2009) 2.19
Ubiquitin conjugation is not required for the degradation of oxidized proteins by proteasome. J Biol Chem (2002) 2.16
Lipofuscin: formation, distribution, and metabolic consequences. Ann N Y Acad Sci (2007) 1.93
Basic principles and emerging concepts in the redox control of transcription factors. Antioxid Redox Signal (2011) 1.82
Regulation of proteasome-mediated protein degradation during oxidative stress and aging. Biol Chem (2008) 1.80
European best practice guidelines for cystic fibrosis neonatal screening. J Cyst Fibros (2009) 1.75
The immunoproteasome, the 20S proteasome and the PA28αβ proteasome regulator are oxidative-stress-adaptive proteolytic complexes. Biochem J (2010) 1.65
Magnetic resonance imaging detects changes in structure and perfusion, and response to therapy in early cystic fibrosis lung disease. Am J Respir Crit Care Med (2014) 1.64
Pathological aspects of lipid peroxidation. Free Radic Res (2010) 1.56
Mitochondrial nitric oxide synthase. Trends Pharmacol Sci (2005) 1.50
Proteasome inhibition by paired helical filament-tau in brains of patients with Alzheimer's disease. J Neurochem (2003) 1.48
Progesterone and estrogen regulate oxidative metabolism in brain mitochondria. Endocrinology (2008) 1.46
c-Jun N-terminal kinase regulates mitochondrial bioenergetics by modulating pyruvate dehydrogenase activity in primary cortical neurons. J Neurochem (2007) 1.44
Multiple breath washout is feasible in the clinical setting and detects abnormal lung function in infants and young children with cystic fibrosis. Respiration (2014) 1.43
Immunoproteasome and LMP2 polymorphism in aged and Alzheimer's disease brains. Neurobiol Aging (2006) 1.42
Regulation of mitochondrial glutathione redox status and protein glutathionylation by respiratory substrates. J Biol Chem (2010) 1.37
Catalytic mechanisms and specificities of glutathione peroxidases: variations of a basic scheme. Biochim Biophys Acta (2009) 1.33
Trends in selenium biochemistry. Nat Prod Rep (2002) 1.33
The proteasome and its role in the degradation of oxidized proteins. IUBMB Life (2008) 1.32
Mitochondrial energy metabolism and redox signaling in brain aging and neurodegeneration. Antioxid Redox Signal (2012) 1.32
Nitric oxide and cell signaling pathways in mitochondrial-dependent apoptosis. Biol Chem (2002) 1.32
Intracellular metabolism of 4-hydroxynonenal. Mol Aspects Med (2003) 1.28
Clinical oxidation parameters of aging. Free Radic Res (2006) 1.26
Hemodynamics influences vascular peroxynitrite formation: Implication for low-density lipoprotein apo-B-100 nitration. Free Radic Biol Med (2006) 1.25
Multiple thioredoxin-mediated routes to detoxify hydroperoxides in Mycobacterium tuberculosis. Arch Biochem Biophys (2004) 1.25
Kinetics of peroxiredoxins and their role in the decomposition of peroxynitrite. Subcell Biochem (2007) 1.23
On the mechanism and biology of cytochrome oxidase inhibition by nitric oxide. Proc Natl Acad Sci U S A (2004) 1.23
c-Jun N-terminal kinase (JNK)-mediated modulation of brain mitochondria function: new target proteins for JNK signalling in mitochondrion-dependent apoptosis. Biochem J (2003) 1.22
Phosphorylation inhibits turnover of the tau protein by the proteasome: influence of RCAN1 and oxidative stress. Biochem J (2006) 1.22
Lipofuscin: formation, effects and role of macroautophagy. Redox Biol (2013) 1.21
Lipoic acid: energy metabolism and redox regulation of transcription and cell signaling. J Clin Biochem Nutr (2010) 1.20
Oxygen causes cell death in the developing brain. Neurobiol Dis (2004) 1.18
Proteasomal defense of oxidative protein modifications. Antioxid Redox Signal (2006) 1.18
Validation of Trypanosoma brucei trypanothione synthetase as drug target. Free Radic Biol Med (2004) 1.18
Sites and mechanisms of aconitase inactivation by peroxynitrite: modulation by citrate and glutathione. Biochemistry (2005) 1.17
Age-associated analysis of oxidative stress parameters in human plasma and erythrocytes. Free Radic Res (2006) 1.14
2-Deoxy-D-glucose treatment induces ketogenesis, sustains mitochondrial function, and reduces pathology in female mouse model of Alzheimer's disease. PLoS One (2011) 1.14
Inquilinus limosus in patients with cystic fibrosis, Germany. Emerg Infect Dis (2005) 1.14
(-)Epicatechin stimulates ERK-dependent cyclic AMP response element activity and up-regulates GluR2 in cortical neurons. J Neurochem (2007) 1.13
Reversible inhibition of mammalian glutamine synthetase by tyrosine nitration. FEBS Lett (2006) 1.12
Protein oxidation in aging and the removal of oxidized proteins. J Proteomics (2013) 1.11
Complementary antioxidant defense by cytoplasmic and mitochondrial peroxiredoxins in Leishmania infantum. Free Radic Biol Med (2002) 1.09
Trypanosoma brucei and Trypanosoma cruzi tryparedoxin peroxidases catalytically detoxify peroxynitrite via oxidation of fast reacting thiols. J Biol Chem (2004) 1.08
Akt1 intramitochondrial cycling is a crucial step in the redox modulation of cell cycle progression. PLoS One (2009) 1.07
Relative contributions of heart mitochondria glutathione peroxidase and catalase to H(2)O(2) detoxification in in vivo conditions. Free Radic Biol Med (2002) 1.07
The catalytic site of glutathione peroxidases. Antioxid Redox Signal (2008) 1.07
Lipofuscin: detection and quantification by microscopic techniques. Methods Mol Biol (2010) 1.07
Decline in mitochondrial bioenergetics and shift to ketogenic profile in brain during reproductive senescence. Biochim Biophys Acta (2010) 1.06
Oxidized proteins: intracellular distribution and recognition by the proteasome. Arch Biochem Biophys (2007) 1.06
Shift in brain metabolism in late onset Alzheimer's disease: implications for biomarkers and therapeutic interventions. Mol Aspects Med (2011) 1.05
Protein oxidation and proteolysis. Biol Chem (2006) 1.05
MAPK signaling in neurodegeneration: influences of flavonoids and of nitric oxide. Neurobiol Aging (2002) 1.05
Kinetics and redox-sensitive oligomerisation reveal negative subunit cooperativity in tryparedoxin peroxidase of Trypanosoma brucei brucei. Biol Chem (2003) 1.04
Iron oxide particles for molecular magnetic resonance imaging cause transient oxidative stress in rat macrophages. Free Radic Biol Med (2004) 1.04
Activation of c-Jun-N-terminal kinase and decline of mitochondrial pyruvate dehydrogenase activity during brain aging. FEBS Lett (2009) 1.03
Advances in methods for the determination of biologically relevant lipid peroxidation products. Free Radic Res (2010) 1.02
Male fertility is linked to the selenoprotein phospholipid hydroperoxide glutathione peroxidase. Biol Reprod (2002) 1.01
Depletion of the thioredoxin homologue tryparedoxin impairs antioxidative defence in African trypanosomes. Biochem J (2007) 1.01
Beta-carotene cleavage products induce oxidative stress in vitro by impairing mitochondrial respiration. FASEB J (2002) 1.00
Redox activation of mitochondrial intermembrane space Cu,Zn-superoxide dismutase. Biochem J (2005) 1.00
Distinct promoters determine alternative transcription of gpx-4 into phospholipid-hydroperoxide glutathione peroxidase variants. J Biol Chem (2003) 1.00
Is there a role of glutathione peroxidases in signaling and differentiation? Biofactors (2003) 1.00
The thioredoxin specificity of Drosophila GPx: a paradigm for a peroxiredoxin-like mechanism of many glutathione peroxidases. J Mol Biol (2006) 1.00
Dynamic adaptation of liver mitochondria to chronic alcohol feeding in mice: biogenesis, remodeling, and functional alterations. J Biol Chem (2012) 0.99
Lipofuscin-bound iron is a major intracellular source of oxidants: role in senescent cells. Free Radic Biol Med (2010) 0.99
Protein modification elicited by oxidized low-density lipoprotein (LDL) in endothelial cells: protection by (-)-epicatechin. Free Radic Biol Med (2006) 0.98
Neuronal apoptotic bodies: phagocytosis and degradation by primary microglial cells. FASEB J (2004) 0.98
The energy-redox axis in aging and age-related neurodegeneration. Adv Drug Deliv Rev (2009) 0.98
Peroxidase: a term of many meanings. Antioxid Redox Signal (2008) 0.98
H2O2 delivery to cells: steady-state versus bolus addition. Methods Enzymol (2013) 0.98
Trypanothione synthesis in crithidia revisited. J Biol Chem (2004) 0.98
Mitochondria: the cellular hub of the dynamic coordinated network. Antioxid Redox Signal (2015) 0.97
Dietary thioproline decreases spontaneous food intake and increases survival and neurological function in mice. Antioxid Redox Signal (2007) 0.97
Insights into the redox biology of Trypanosoma cruzi: Trypanothione metabolism and oxidant detoxification. Free Radic Biol Med (2008) 0.97
Mitochondrial thiols in the regulation of cell death pathways. Antioxid Redox Signal (2012) 0.97
Ovarian hormone loss induces bioenergetic deficits and mitochondrial β-amyloid. Neurobiol Aging (2011) 0.97
Silencing of nicotinamide nucleotide transhydrogenase impairs cellular redox homeostasis and energy metabolism in PC12 cells. Biochim Biophys Acta (2011) 0.96
Protein oxidative modification in the aging organism and the role of the ubiquitin proteasomal system. Curr Pharm Des (2011) 0.95
Role of nitric oxide-mediated glutathionylation in neuronal function: potential regulation of energy utilization. Biochem J (2010) 0.95
Mitochondrial respiratory chain and thioredoxin reductase regulate intermembrane Cu,Zn-superoxide dismutase activity: implications for mitochondrial energy metabolism and apoptosis. Biochem J (2007) 0.94
Hippocampal mitochondrial dysfunction in rat aging. Am J Physiol Regul Integr Comp Physiol (2007) 0.94
The proteasome and its role in nuclear protein maintenance. Exp Gerontol (2007) 0.94
Determination of GSH, GSSG, and GSNO using HPLC with electrochemical detection. Methods Enzymol (2010) 0.94
Lysosomal, cytoskeletal, and metabolic alterations in cardiomyopathy of cathepsin L knockout mice. FASEB J (2006) 0.94
The thiol-based redox networks of pathogens: unexploited targets in the search for new drugs. Biofactors (2006) 0.94
Beta-carotene breakdown products may impair mitochondrial functions--potential side effects of high-dose beta-carotene supplementation. J Nutr Biochem (2005) 0.93
Intracellular distribution of oxidized proteins and proteasome in HT22 cells during oxidative stress. Free Radic Biol Med (2005) 0.93
Oxidation-induced ferritin turnover in microglial cells: role of proteasome. Free Radic Biol Med (2005) 0.93
Protein oxidative modifications in the ageing brain: consequence for the onset of neurodegenerative disease. Free Radic Res (2010) 0.93
The modulation of mitochondrial nitric-oxide synthase activity in rat brain development. J Biol Chem (2002) 0.93
Oxidants and antioxidants revisited. New concepts of oxidative stress. Free Radic Res (2007) 0.93
Anti-fibrosclerotic effects of shock wave therapy in lipedema and cellulite. Biofactors (2005) 0.92
Lipofuscin inhibits the proteasome by binding to surface motifs. Free Radic Biol Med (2010) 0.92
The proteasome and the degradation of oxidized proteins: Part I-structure of proteasomes. Redox Biol (2013) 0.92