Published in Nucleic Acids Res on January 26, 2006
Global variation in copy number in the human genome. Nature (2006) 57.50
Consensus statement: chromosomal microarray is a first-tier clinical diagnostic test for individuals with developmental disabilities or congenital anomalies. Am J Hum Genet (2010) 13.70
High-resolution genomic profiling of chromosomal aberrations using Infinium whole-genome genotyping. Genome Res (2006) 10.45
Gastric cancer. Lancet (2009) 7.27
Methods and strategies for analyzing copy number variation using DNA microarrays. Nat Genet (2007) 5.64
Accurate and reliable high-throughput detection of copy number variation in the human genome. Genome Res (2006) 5.50
Bacterial artificial chromosome-emulation oligonucleotide arrays for targeted clinical array-comparative genomic hybridization analyses. Genet Med (2008) 2.36
A portrait of copy-number polymorphism in Drosophila melanogaster. Proc Natl Acad Sci U S A (2007) 2.24
Normalization of array-CGH data: influence of copy number imbalances. BMC Genomics (2007) 1.57
Flexible and accurate detection of genomic copy-number changes from aCGH. PLoS Comput Biol (2007) 1.54
A single-sample method for normalizing and combining full-resolution copy numbers from multiple platforms, labs and analysis methods. Bioinformatics (2009) 1.53
wuHMM: a robust algorithm to detect DNA copy number variation using long oligonucleotide microarray data. Nucleic Acids Res (2008) 1.48
Male-to-female sex reversal associated with an approximately 250 kb deletion upstream of NR0B1 (DAX1). Hum Genet (2007) 1.36
Strategies for the detection of copy number and other structural variants in the human genome. Hum Genomics (2006) 1.32
DNA copy number analysis of fresh and formalin-fixed specimens by shallow whole-genome sequencing with identification and exclusion of problematic regions in the genome assembly. Genome Res (2014) 1.28
Array-CGH in patients with Kabuki-like phenotype: identification of two patients with complex rearrangements including 2q37 deletions and no other recurrent aberration. BMC Med Genet (2008) 1.28
Combined array-comparative genomic hybridization and single-nucleotide polymorphism-loss of heterozygosity analysis reveals complex genetic alterations in cervical cancer. BMC Genomics (2007) 1.24
Cytogenetically balanced translocations are associated with focal copy number alterations. Hum Genet (2006) 1.23
A new look towards BAC-based array CGH through a comprehensive comparison with oligo-based array CGH. BMC Genomics (2007) 1.17
Random DNA fragmentation allows detection of single-copy, single-exon alterations of copy number by oligonucleotide array CGH in clinical FFPE samples. Nucleic Acids Res (2009) 1.17
Mechanisms and consequences of small supernumerary marker chromosomes: from Barbara McClintock to modern genetic-counseling issues. Am J Hum Genet (2008) 1.09
Safety paradigm: genetic evaluation of therapeutic grade human embryonic stem cells. J R Soc Interface (2010) 1.02
ADaCGH: A parallelized web-based application and R package for the analysis of aCGH data. PLoS One (2007) 0.99
Detecting structural variations in the human genome using next generation sequencing. Brief Funct Genomics (2011) 0.98
Gene-resolution analysis of DNA copy number variation using oligonucleotide expression microarrays. BMC Genomics (2007) 0.98
CanGEM: mining gene copy number changes in cancer. Nucleic Acids Res (2007) 0.97
Analysis of severely affected patients with dihydropyrimidine dehydrogenase deficiency reveals large intragenic rearrangements of DPYD and a de novo interstitial deletion del(1)(p13.3p21.3). Hum Genet (2009) 0.97
Computational methods for the analysis of array comparative genomic hybridization. Cancer Inform (2007) 0.96
The Growing Importance of CNVs: New Insights for Detection and Clinical Interpretation. Front Genet (2013) 0.96
Bayesian hierarchical mixture modeling to assign copy number from a targeted CNV array. Genet Epidemiol (2011) 0.93
Opening the archives for state of the art tumour genetic research: sample processing for array-CGH using decalcified, formalin-fixed, paraffin-embedded tissue-derived DNA samples. BMC Res Notes (2011) 0.89
Genome profiling of ovarian adenocarcinomas using pangenomic BACs microarray comparative genomic hybridization. Mol Cytogenet (2008) 0.89
A robust method to analyze copy number alterations of less than 100 kb in single cells using oligonucleotide array CGH. PLoS One (2013) 0.88
Genome-wide comparison of paired fresh frozen and formalin-fixed paraffin-embedded gliomas by custom BAC and oligonucleotide array comparative genomic hybridization: facilitating analysis of archival gliomas. Acta Neuropathol (2010) 0.87
Evaluation of genome coverage and fidelity of multiple displacement amplification from single cells by SNP array. Mol Hum Reprod (2009) 0.87
Detection of recurrent copy number alterations in the genome: taking among-subject heterogeneity seriously. BMC Bioinformatics (2009) 0.85
Preservation of skin DNA for oligonucleotide array CGH studies: a feasibility study. Arch Dermatol Res (2007) 0.83
PAIR: paired allelic log-intensity-ratio-based normalization method for SNP-CGH arrays. Bioinformatics (2012) 0.83
Progenetix: 12 years of oncogenomic data curation. Nucleic Acids Res (2013) 0.82
De novo complex intra chromosomal rearrangement after ICSI: characterisation by BACs micro array-CGH. Mol Cytogenet (2008) 0.81
Comparative genomic hybridization on spotted oligonucleotide microarrays. Methods Mol Biol (2009) 0.81
Array-CGH and multipoint FISH to decode complex chromosomal rearrangements. BMC Genomics (2006) 0.81
Array comparative genomic hybridization analysis identifies recurrent gain of chromosome 2p25.3 involving the ACP1 and MYCN genes in chronic lymphocytic leukemia. Clin Lymphoma Myeloma Leuk (2011) 0.80
Integrated analysis of copy number alteration and RNA expression profiles of cancer using a high-resolution whole-genome oligonucleotide array. Exp Mol Med (2009) 0.80
Array Comparative Genomic Hybridizations: assessing the ability to recapture evolutionary relationships using an in silico approach. BMC Genomics (2011) 0.79
A response to Yu et al. "A forward-backward fragment assembling algorithm for the identification of genomic amplification and deletion breakpoints using high-density single nucleotide polymorphism (SNP) array", BMC Bioinformatics 2007, 8: 145. BMC Bioinformatics (2007) 0.79
Absence/presence calling in microarray-based CGH experiments with non-model organisms. Nucleic Acids Res (2014) 0.78
Genomic Variation: Lessons Learned from Whole-Genome CNV Analysis. Curr Genet Med Rep (2014) 0.76
Report of the EORTC-PAMM Meeting, Brussels, 16-18 March 2009: new strategies for a targeted and personalised therapy of cancer. Ecancermedicalscience (2009) 0.75
Battling cancer on many fronts. Meeting on New Battlefields in Human Cancer--Attacking in Many Fronts. EMBO Rep (2008) 0.75
aCGH-MAS: analysis of aCGH by means of multiagent system. Biomed Res Int (2015) 0.75
A Robust Protocol for Using Multiplexed Droplet Digital PCR to Quantify Somatic Copy Number Alterations in Clinical Tissue Specimens. PLoS One (2016) 0.75
Penalized weighted low-rank approximation for robust recovery of recurrent copy number variations. BMC Bioinformatics (2015) 0.75
Large-scale copy number polymorphism in the human genome. Science (2004) 34.64
Fine-scale structural variation of the human genome. Nat Genet (2005) 24.31
High resolution analysis of DNA copy number variation using comparative genomic hybridization to microarrays. Nat Genet (1998) 21.52
Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors. Science (1992) 16.38
Genome-wide analysis of DNA copy-number changes using cDNA microarrays. Nat Genet (1999) 14.96
Segmental duplications and copy-number variation in the human genome. Am J Hum Genet (2005) 13.33
Assembly of microarrays for genome-wide measurement of DNA copy number. Nat Genet (2001) 11.06
An integrated view of copy number and allelic alterations in the cancer genome using single nucleotide polymorphism arrays. Cancer Res (2004) 8.86
Matrix-based comparative genomic hybridization: biochips to screen for genomic imbalances. Genes Chromosomes Cancer (1997) 8.27
Representational oligonucleotide microarray analysis: a high-resolution method to detect genome copy number variation. Genome Res (2003) 7.86
A tiling resolution DNA microarray with complete coverage of the human genome. Nat Genet (2004) 7.68
Analysis of chromosome breakpoints in neuroblastoma at sub-kilobase resolution using fine-tiling oligonucleotide array CGH. Genes Chromosomes Cancer (2005) 7.53
Homozygous deletions and chromosome amplifications in human lung carcinomas revealed by single nucleotide polymorphism array analysis. Cancer Res (2005) 6.93
Array comparative genomic hybridization and its applications in cancer. Nat Genet (2005) 6.69
High-resolution genomic profiles of human lung cancer. Proc Natl Acad Sci U S A (2005) 6.52
DNA microarrays for comparative genomic hybridization based on DOP-PCR amplification of BAC and PAC clones. Genes Chromosomes Cancer (2003) 4.68
Genome-wide single nucleotide polymorphism analysis reveals frequent partial uniparental disomy due to somatic recombination in acute myeloid leukemias. Cancer Res (2005) 3.83
Comparative genomic hybridization using oligonucleotide microarrays and total genomic DNA. Proc Natl Acad Sci U S A (2004) 3.82
Genome-wide DNA copy number alterations in head and neck squamous cell carcinomas with or without oncogene-expressing human papillomavirus. Oncogene (2006) 2.56
Epigenome analyses using BAC microarrays identify evolutionary conservation of tissue-specific methylation of SHANK3. Nat Genet (2005) 2.51
High-resolution global profiling of genomic alterations with long oligonucleotide microarray. Cancer Res (2004) 2.45
Genomics: massively parallel sequencing. Nature (2005) 2.05
Human and mouse oligonucleotide-based array CGH. Nucleic Acids Res (2005) 2.03
Identification of disease genes by whole genome CGH arrays. Hum Mol Genet (2005) 1.85
Exon array CGH: detection of copy-number changes at the resolution of individual exons in the human genome. Am J Hum Genet (2005) 1.78
Frequency of new copy number variation in humans. Nat Genet (2005) 1.71
Mapping segmental and sequence variations among laboratory mice using BAC array CGH. Genome Res (2005) 1.71
High resolution microarray comparative genomic hybridisation analysis using spotted oligonucleotides. J Clin Pathol (2004) 1.71
Microarray-based comparative genomic hybridization and its applications in human genetics. Clin Genet (2004) 1.61
Genomic microarrays in the spotlight. Trends Genet (2004) 1.55
Genomic profiling of gastric cancer predicts lymph node status and survival. Oncogene (2003) 1.40
Array-based comparative genomic hybridization from formalin-fixed, paraffin-embedded breast tumors. J Mol Diagn (2005) 1.40
Array CGH technologies and their applications to cancer genomes. Chromosome Res (2005) 1.33
Microarray comparative genomic hybridization detection of chromosomal imbalances in uterine cervix carcinoma. BMC Cancer (2005) 1.27
Determination of amplicon boundaries at 20q13.2 in tissue samples of human gastric adenocarcinomas by high-resolution microarray comparative genomic hybridization. J Pathol (2003) 1.21
Application of ROMA (representational oligonucleotide microarray analysis) to patients with cytogenetic rearrangements. Genet Med (2005) 1.15
Electrochemically directed synthesis of oligonucleotides for DNA microarray fabrication. Nucleic Acids Res (2005) 1.15
Comprehensive genome-wide comparison of DNA and RNA level scan using microarray technology for identification of candidate cancer-related genes in the HL-60 cell line. Cancer Genet Cytogenet (2003) 1.02
Expression microarray analysis and oligo array comparative genomic hybridization of acquired gemcitabine resistance in mouse colon reveals selection for chromosomal aberrations. Cancer Res (2005) 1.00
Genomic stability and functional activity may be lost in telomerase-transduced human CD8+ T lymphocytes. Blood (2005) 0.88
The molecular biology of head and neck cancer. Nat Rev Cancer (2010) 9.84
Detection, clinical relevance and specific biological properties of disseminating tumour cells. Nat Rev Cancer (2008) 7.99
Dissecting the metastatic cascade. Nat Rev Cancer (2004) 6.32
A genetic explanation of Slaughter's concept of field cancerization: evidence and clinical implications. Cancer Res (2003) 5.04
A novel algorithm for reliable detection of human papillomavirus in paraffin embedded head and neck cancer specimen. Int J Cancer (2007) 4.29
Genetic patterns in head and neck cancers that contain or lack transcriptionally active human papillomavirus. J Natl Cancer Inst (2004) 3.67
Resolving the resolution of array CGH. Genomics (2007) 3.66
Gastric cancer risk in patients with premalignant gastric lesions: a nationwide cohort study in the Netherlands. Gastroenterology (2008) 3.18
Regulation of the adenomatous polyposis coli gene by the miR-135 family in colorectal cancer. Cancer Res (2008) 3.06
Myosin IXB variant increases the risk of celiac disease and points toward a primary intestinal barrier defect. Nat Genet (2005) 2.71
Predictive factors for outcome in a phase II study of gefitinib in second-line treatment of advanced esophageal cancer patients. J Clin Oncol (2006) 2.33
N-Myc downstream-regulated gene 4 (NDRG4): a candidate tumor suppressor gene and potential biomarker for colorectal cancer. J Natl Cancer Inst (2009) 2.22
Human and mouse oligonucleotide-based array CGH. Nucleic Acids Res (2005) 2.03
Epigenetic silencing of cyclooxygenase-2 affects clinical outcome in gastric cancer. J Clin Oncol (2007) 1.97
Low-grade dysplasia in Barrett's esophagus: overdiagnosed and underestimated. Am J Gastroenterol (2010) 1.90
Somatic mutations and deletions of the E-cadherin gene predict poor survival of patients with gastric cancer. J Clin Oncol (2013) 1.89
Methylation of TFPI2 in stool DNA: a potential novel biomarker for the detection of colorectal cancer. Cancer Res (2009) 1.80
GATA4 and GATA5 are potential tumor suppressors and biomarkers in colorectal cancer. Clin Cancer Res (2009) 1.78
In vivo induction of resistance to gemcitabine results in increased expression of ribonucleotide reductase subunit M1 as the major determinant. Cancer Res (2005) 1.76
Methylation-mediated silencing and tumour suppressive function of hsa-miR-124 in cervical cancer. Mol Cancer (2010) 1.69
Coordinated epidermal growth factor receptor pathway gene overexpression predicts epidermal growth factor receptor inhibitor sensitivity in pancreatic cancer. Cancer Res (2008) 1.69
Risk of malignant progression in patients with Barrett's oesophagus: a Dutch nationwide cohort study. Gut (2010) 1.68
Higher fecal immunochemical test cutoff levels: lower positivity rates but still acceptable detection rates for early-stage colorectal cancers. Cancer Epidemiol Biomarkers Prev (2010) 1.55
Colorectal cancer epigenetics: complex simplicity. J Clin Oncol (2011) 1.47
Genomic alterations in primary gastric adenocarcinomas correlate with clinicopathological characteristics and survival. Cell Oncol (2004) 1.46
Smoothing waves in array CGH tumor profiles. Bioinformatics (2009) 1.45
Risk of colorectal cancer in patients with Barrett's esophagus: A Dutch population-based study. Am J Gastroenterol (2009) 1.44
Second primary tumors and field cancerization in oral and oropharyngeal cancer: molecular techniques provide new insights and definitions. Head Neck (2002) 1.41
Macrophages direct tumour histology and clinical outcome in a colon cancer model. J Pathol (2005) 1.40
Genomic profiling of gastric cancer predicts lymph node status and survival. Oncogene (2003) 1.40
Clinical and molecular characteristics of squamous cell carcinomas from Fanconi anemia patients. J Natl Cancer Inst (2008) 1.36
A genetic progression model of oral cancer: current evidence and clinical implications. J Oral Pathol Med (2004) 1.36
Advances and applications of oral cancer basic research. Oral Oncol (2011) 1.33
Increasing prevalence rates of HPV attributable oropharyngeal squamous cell carcinomas in the Netherlands as assessed by a validated test algorithm. Int J Cancer (2012) 1.31
Lack of microRNA-101 causes E-cadherin functional deregulation through EZH2 up-regulation in intestinal gastric cancer. J Pathol (2012) 1.30
Endoscopic trimodal imaging versus standard video endoscopy for detection of early Barrett's neoplasia: a multicenter, randomized, crossover study in general practice. Gastrointest Endosc (2010) 1.27
Integrated genomic and transcriptional profiling identifies chromosomal loci with altered gene expression in cervical cancer. Genes Chromosomes Cancer (2008) 1.26
Across array comparative genomic hybridization: a strategy to reduce reference channel hybridizations. Genes Chromosomes Cancer (2008) 1.25
Molecular diagnosis of surgical margins and local recurrence in head and neck cancer patients: a prospective study. Clin Cancer Res (2004) 1.24
CGHMultiArray: exact P-values for multi-array comparative genomic hybridization data. Bioinformatics (2005) 1.23
Test performance of immunologic fecal occult blood testing and sigmoidoscopy compared with primary colonoscopy screening for colorectal advanced adenomas. Cancer Prev Res (Phila) (2011) 1.23
Rapid quantification of myocardial fibrosis: a new macro-based automated analysis. Cell Oncol (Dordr) (2011) 1.22
Determination of amplicon boundaries at 20q13.2 in tissue samples of human gastric adenocarcinomas by high-resolution microarray comparative genomic hybridization. J Pathol (2003) 1.21
Multiple head and neck tumors frequently originate from a single preneoplastic lesion. Am J Pathol (2002) 1.20
Protein expression of B-cell lymphoma gene 6 (BCL-6) in invasive breast cancer is associated with cyclin D1 and hypoxia-inducible factor-1alpha (HIF-1alpha). Oncogene (2003) 1.20
Expanding fields of genetically altered cells in head and neck squamous carcinogenesis. Semin Cancer Biol (2005) 1.20
Does delay in diagnosing colorectal cancer in symptomatic patients affect tumor stage and survival? A population-based observational study. BMC Cancer (2010) 1.20
Genomic profiles associated with early micrometastasis in lung cancer: relevance of 4q deletion. Clin Cancer Res (2009) 1.19
KRAS and BRAF mutation analysis in routine molecular diagnostics: comparison of three testing methods on formalin-fixed, paraffin-embedded tumor-derived DNA. J Mol Diagn (2012) 1.19
Genetically altered fields as origin of locally recurrent head and neck cancer: a retrospective study. Clin Cancer Res (2004) 1.18
Subnuclear proteomics in colorectal cancer: identification of proteins enriched in the nuclear matrix fraction and regulation in adenoma to carcinoma progression. Mol Cell Proteomics (2010) 1.16
Identification of key genes for carcinogenic pathways associated with colorectal adenoma-to-carcinoma progression. Tumour Biol (2010) 1.16
Dendritic cells recognize tumor-specific glycosylation of carcinoembryonic antigen on colorectal cancer cells through dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin. Cancer Res (2005) 1.16
TPX2 and AURKA promote 20q amplicon-driven colorectal adenoma to carcinoma progression. Gut (2011) 1.15
The C-type lectin MGL expressed by dendritic cells detects glycan changes on MUC1 in colon carcinoma. Cancer Immunol Immunother (2006) 1.14
Integration of gene dosage and gene expression in non-small cell lung cancer, identification of HSP90 as potential target. PLoS One (2008) 1.14
Human papilloma virus in head and neck cancer: the need for a standardised assay to assess the full clinical importance. Eur J Cancer (2009) 1.14
Comparative molecular and histological grading of epithelial dysplasia of the oral cavity and the oropharynx. J Pathol (2003) 1.13
Characterization of the human Ly-6 antigens, the newly annotated member Ly-6K included, as molecular markers for head-and-neck squamous cell carcinoma. Int J Cancer (2003) 1.12
Generation and molecular characterization of head and neck squamous cell lines of fanconi anemia patients. Cancer Res (2005) 1.12
Mutated p53 as a molecular marker for the diagnosis of head and neck cancer. J Pathol (2002) 1.11
Focal aberrations indicate EYA2 and hsa-miR-375 as oncogene and tumor suppressor in cervical carcinogenesis. Genes Chromosomes Cancer (2012) 1.10
Genetic classification of oral and oropharyngeal carcinomas identifies subgroups with a different prognosis. Cell Oncol (2009) 1.10
Performance of amplicon-based next generation DNA sequencing for diagnostic gene mutation profiling in oncopathology. Cell Oncol (Dordr) (2014) 1.09
Prognostic significance of truncating TP53 mutations in head and neck squamous cell carcinoma. Clin Cancer Res (2011) 1.08
Genetic reprogramming of tumor cells by zinc finger transcription factors. Proc Natl Acad Sci U S A (2005) 1.07
High-risk human papillomavirus-positive lung cancer: molecular evidence for a pattern of pulmonary metastasis. J Thorac Oncol (2013) 1.06
Promoter DNA methylation of oncostatin m receptor-beta as a novel diagnostic and therapeutic marker in colon cancer. PLoS One (2009) 1.06
A noninvasive genetic screening test to detect oral preneoplastic lesions. Lab Invest (2005) 1.06
Biopsy strategies for endoscopic surveillance of pre-malignant gastric lesions. Helicobacter (2010) 1.05
Proteomics of colorectal cancer: overview of discovery studies and identification of commonly identified cancer-associated proteins and candidate CRC serum markers. J Proteomics (2010) 1.04
High resolution analysis of DNA copy-number aberrations of chromosomes 8, 13, and 20 in gastric cancers. Virchows Arch (2009) 1.04
Candidate driver genes in focal chromosomal aberrations of stage II colon cancer. J Pathol (2010) 1.03
Proteomics in colorectal cancer translational research: biomarker discovery for clinical applications. Clin Biochem (2012) 1.03
Promoter methylation precedes chromosomal alterations in colorectal cancer development. Cell Oncol (2006) 1.03
Promoter CpG island hypermethylation- and H3K9me3 and H3K27me3-mediated epigenetic silencing targets the deleted in colon cancer (DCC) gene in colorectal carcinogenesis without affecting neighboring genes on chromosomal region 18q21. Carcinogenesis (2009) 1.03
Colorectal adenoma to carcinoma progression is accompanied by changes in gene expression associated with ageing, chromosomal instability, and fatty acid metabolism. Cell Oncol (Dordr) (2012) 1.02
Interval cancers after colonoscopy-insights and recommendations. Nat Rev Gastroenterol Hepatol (2012) 1.02
Alternative cleavage and polyadenylation during colorectal cancer development. Clin Cancer Res (2012) 1.02
Molecular tests for colorectal cancer screening. Clin Colorectal Cancer (2011) 1.01
Second field tumors: a new opportunity for cancer prevention? Oncologist (2005) 1.01
Differential glycosylation of MUC1 and CEACAM5 between normal mucosa and tumour tissue of colon cancer patients. Int J Cancer (2011) 1.01
Time trends in the prevalence of HPV in oropharyngeal squamous cell carcinomas in northern Spain (1990-2009). Int J Cancer (2013) 1.01
A homozygous MSH6 mutation in a child with café-au-lait spots, oligodendroglioma and rectal cancer. Fam Cancer (2004) 1.00