Published in Biophys J on January 27, 2006
Sequence of late molecular events in the activation of rhodopsin. Proc Natl Acad Sci U S A (2007) 1.85
Osmolyte perturbation reveals conformational equilibria in spin-labeled proteins. Protein Sci (2009) 1.60
Structural and dynamical changes in an alpha-subunit of a heterotrimeric G protein along the activation pathway. Proc Natl Acad Sci U S A (2006) 1.33
Substrate-dependent unfolding of the energy coupling motif of a membrane transport protein determined by double electron-electron resonance. Biochemistry (2006) 1.20
Conformational exchange in a membrane transport protein is altered in protein crystals. Biophys J (2010) 1.17
Inter-spin distance determination using L-band (1-2 GHz) non-adiabatic rapid sweep electron paramagnetic resonance (NARS EPR). J Magn Reson (2012) 1.01
Substrate-dependent transmembrane signaling in TonB-dependent transporters is not conserved. Proc Natl Acad Sci U S A (2007) 0.99
Osmolytes modulate conformational exchange in solvent-exposed regions of membrane proteins. Protein Sci (2010) 0.97
Membrane simulations of OpcA: gating in the loops? Biophys J (2006) 0.96
Gating at both ends and breathing in the middle: conformational dynamics of TolC. Biophys J (2008) 0.91
Pulsed EPR distance measurements in soluble proteins by site-directed spin labeling (SDSL). Curr Protoc Protein Sci (2013) 0.90
Induced conformational changes in the activation of the Pseudomonas aeruginosa type III toxin, ExoU. Biophys J (2011) 0.87
Osmotically induced helix-coil transition in poly(glutamic acid). Biophys J (2008) 0.87
The juxtamembrane linker of full-length synaptotagmin 1 controls oligomerization and calcium-dependent membrane binding. J Biol Chem (2014) 0.85
Identifying and quantitating conformational exchange in membrane proteins using site-directed spin labeling. Acc Chem Res (2014) 0.84
Probing Protein Secondary Structure using EPR: Investigating a Dynamic Region of Visual Arrestin. Appl Magn Reson (2012) 0.77
Spin labeling and Double Electron-Electron Resonance (DEER) to Deconstruct Conformational Ensembles of HIV Protease. Methods Enzymol (2015) 0.77
Effect of osmolytes on the binding of EGR1 transcription factor to DNA. Biopolymers (2015) 0.75
Identifying conformational changes with site-directed spin labeling. Nat Struct Biol (2000) 5.76
Motion of spin-labeled side chains in T4 lysozyme. Correlation with protein structure and dynamics. Biochemistry (1996) 5.52
Protein solvation in allosteric regulation: a water effect on hemoglobin. Science (1992) 3.60
Osmotic stress, crowding, preferential hydration, and binding: A comparison of perspectives. Proc Natl Acad Sci U S A (2000) 2.72
Touch and go: tying TonB to transport. Mol Microbiol (2003) 2.72
Substrate-induced transmembrane signaling in the cobalamin transporter BtuB. Nat Struct Biol (2003) 2.41
Forcing thermodynamically unfolded proteins to fold. J Biol Chem (1998) 2.34
Vapor pressure osmometry studies of osmolyte-protein interactions: implications for the action of osmoprotectants in vivo and for the interpretation of "osmotic stress" experiments in vitro. Biochemistry (2000) 2.24
Acquisition of siderophores in gram-negative bacteria. Nat Rev Mol Cell Biol (2003) 2.24
Osmolyte-driven contraction of a random coil protein. Proc Natl Acad Sci U S A (1998) 2.22
Steric exclusion is the principal source of the preferential hydration of proteins in the presence of polyethylene glycols. Protein Sci (1992) 2.04
Solute inaccessible aqueous volume changes during opening of the potassium channel of the squid giant axon. Biophys J (1990) 2.02
Mapping backbone dynamics in solution with site-directed spin labeling: GCN4-58 bZip free and bound to DNA. Biochemistry (2004) 2.00
Measuring the stability of partly folded proteins using TMAO. Protein Sci (2003) 1.93
Protein hydration, thermodynamic binding, and preferential hydration. Biochemistry (2002) 1.81
Site-directed disulfide bonding reveals an interaction site between energy-coupling protein TonB and BtuB, the outer membrane cobalamin transporter. Proc Natl Acad Sci U S A (1999) 1.80
Probing protein hydration and conformational states in solution. Biophys J (1997) 1.74
Substrate-induced exposure of an energy-coupling motif of a membrane transporter. Nat Struct Biol (2000) 1.42
Probing alamethicin channels with water-soluble polymers. Size-modulated osmotic action. Biophys J (1993) 1.42
Effects of naturally occurring osmolytes on protein stability and solubility: issues important in protein crystallization. Methods (2004) 1.32
Substrate-induced conformational changes of the periplasmic N-terminus of an outer-membrane transporter by site-directed spin labeling. Biochemistry (2003) 1.31
Spectroscopic evidence that osmolytes used in crystallization buffers inhibit a conformation change in a membrane protein. Biochemistry (2003) 1.30
Sequence changes in the ton box region of BtuB affect its transport activities and interaction with TonB protein. J Bacteriol (2000) 1.25
Trimethylamine-N-oxide counteracts urea effects on rabbit muscle lactate dehydrogenase function: a test of the counteraction hypothesis. Biophys J (1998) 1.23
Structure and dynamics of the beta-barrel of the membrane transporter BtuB by site-directed spin labeling. Biochemistry (2002) 1.18
Crystallization and initial X-ray diffraction of BtuB, the integral membrane cobalamin transporter of Escherichia coli. Acta Crystallogr D Biol Crystallogr (2003) 1.12
Differential substrate-induced signaling through the TonB-dependent transporter BtuB. Proc Natl Acad Sci U S A (2003) 1.08
Transport-defective mutations alter the conformation of the energy-coupling motif of an outer membrane transporter. Biochemistry (2001) 1.08
Competing ligands stabilize alternate conformations of the energy coupling motif of a TonB-dependent outer membrane transporter. Proc Natl Acad Sci U S A (2003) 1.02
Membrane mimetic environments alter the conformation of the outer membrane protein BtuB. J Am Chem Soc (2003) 0.90
Revealing nature's cellulase diversity: the digestion mechanism of Caldicellulosiruptor bescii CelA. Science (2013) 3.51
Recent advances and applications of site-directed spin labeling. Curr Opin Struct Biol (2006) 3.12
Electrostatic sequestration of PIP2 on phospholipid membranes by basic/aromatic regions of proteins. Biophys J (2004) 2.66
Solid pseudopapillary tumor of the pancreas: a review of 553 cases in Chinese literature. World J Gastroenterol (2010) 2.16
ZNF804A and schizophrenia susceptibility in Asian populations. Am J Med Genet B Neuropsychiatr Genet (2012) 2.06
NMR solution structure of the integral membrane enzyme DsbB: functional insights into DsbB-catalyzed disulfide bond formation. Mol Cell (2008) 1.92
Common variants on 8p12 and 1q24.2 confer risk of schizophrenia. Nat Genet (2011) 1.88
Genotypic evolution and antigenic drift of H9N2 influenza viruses in China from 1994 to 2008. Vet Microbiol (2010) 1.60
An ALS-associated mutation affecting TDP-43 enhances protein aggregation, fibril formation and neurotoxicity. Nat Struct Mol Biol (2011) 1.58
Dynamic structure of lipid-bound synaptobrevin suggests a nucleation-propagation mechanism for trans-SNARE complex formation. Proc Natl Acad Sci U S A (2009) 1.57
Membrane orientation and position of the C2 domain from cPLA2 by site-directed spin labeling. Biochemistry (2002) 1.57
Position of synaptotagmin I at the membrane interface: cooperative interactions of tandem C2 domains. Biochemistry (2006) 1.54
Mouse model of post-infarct ventricular rupture: time course, strain- and gender-dependency, tensile strength, and histopathology. Cardiovasc Res (2005) 1.52
Membrane-bound orientation and position of the synaptotagmin I C2A domain by site-directed spin labeling. Biochemistry (2003) 1.47
Drug pressure selected mutations in HIV-1 protease alter flap conformations. J Am Chem Soc (2009) 1.41
The structure of the coiled-coil domain of Ndel1 and the basis of its interaction with Lis1, the causal protein of Miller-Dieker lissencephaly. Structure (2007) 1.36
Myristoylated alanine-rich C kinase substrate (MARCKS) sequesters spin-labeled phosphatidylinositol 4,5-bisphosphate in lipid bilayers. J Biol Chem (2002) 1.34
Interflap distances in HIV-1 protease determined by pulsed EPR measurements. J Am Chem Soc (2007) 1.32
Substrate-induced conformational changes of the periplasmic N-terminus of an outer-membrane transporter by site-directed spin labeling. Biochemistry (2003) 1.31
Spectroscopic evidence that osmolytes used in crystallization buffers inhibit a conformation change in a membrane protein. Biochemistry (2003) 1.30
Membrane-bound orientation and position of the synaptotagmin C2B domain determined by site-directed spin labeling. Biochemistry (2005) 1.27
Natural paradigms of plant cell wall degradation. Curr Opin Biotechnol (2009) 1.25
Deletion of macrophage migration inhibitory factor protects the heart from severe ischemia-reperfusion injury: a predominant role of anti-inflammation. J Mol Cell Cardiol (2011) 1.22
Solution structure of the ESCRT-I complex by small-angle X-ray scattering, EPR, and FRET spectroscopy. Proc Natl Acad Sci U S A (2011) 1.22
Relaxin reverses cardiac and renal fibrosis in spontaneously hypertensive rats. Hypertension (2005) 1.22
Substrate-dependent unfolding of the energy coupling motif of a membrane transport protein determined by double electron-electron resonance. Biochemistry (2006) 1.20
Structure and dynamics of the beta-barrel of the membrane transporter BtuB by site-directed spin labeling. Biochemistry (2002) 1.18
Monitoring inhibitor-induced conformational population shifts in HIV-1 protease by pulsed EPR spectroscopy. Biochemistry (2009) 1.18
The combined effects of the 5-HTTLPR and 5-HTR1A genes modulates the relationship between negative life events and major depressive disorder in a Chinese population. J Affect Disord (2008) 1.17
Solution and membrane-bound conformations of the tandem C2A and C2B domains of synaptotagmin 1: Evidence for bilayer bridging. J Mol Biol (2009) 1.17
Conformational exchange in a membrane transport protein is altered in protein crystals. Biophys J (2010) 1.17
Subtype polymorphisms among HIV-1 protease variants confer altered flap conformations and flexibility. J Am Chem Soc (2009) 1.13
Solutes alter the conformation of the ligand binding loops in outer membrane transporters. Biochemistry (2007) 1.12
Ligand of scavenger receptor class A indirectly induces maturation of human blood dendritic cells via production of tumor necrosis factor-alpha. Blood (2009) 1.10
Enhanced production of IL-10 by dendritic cells deficient in CIITA. J Immunol (2005) 1.09
Versatile derivatives of carbohydrate-binding modules for imaging of complex carbohydrates approaching the molecular level of resolution. Biotechniques (2006) 1.08
Guinea pig model for evaluating the potential public health risk of swine and avian influenza viruses. PLoS One (2010) 1.08
Location of the myristoylated alanine-rich C-kinase substrate (MARCKS) effector domain in negatively charged phospholipid bicelles. Biophys J (2003) 1.08
Differential substrate-induced signaling through the TonB-dependent transporter BtuB. Proc Natl Acad Sci U S A (2003) 1.08
Meta-analysis: circulating adiponectin levels and risk of colorectal cancer and adenoma. J Dig Dis (2011) 1.08
Antioxidant enzymes and lipid peroxidation in different forms of schizophrenia treated with typical and atypical antipsychotics. Schizophr Res (2005) 1.07
Expression of human FUS protein in Drosophila leads to progressive neurodegeneration. Protein Cell (2011) 1.06
Phosphatidylinositol 4,5-bisphosphate alters synaptotagmin 1 membrane docking and drives opposing bilayers closer together. Biochemistry (2011) 1.06
Solution structure of the ESCRT-I and -II supercomplex: implications for membrane budding and scission. Structure (2012) 1.06
The calcium-dependent and calcium-independent membrane binding of synaptotagmin 1: two modes of C2B binding. J Mol Biol (2009) 1.05
Novel architecture of family-9 glycoside hydrolases identified in cellulosomal enzymes of Acetivibrio cellulolyticus and Clostridium thermocellum. FEMS Microbiol Lett (2006) 1.05
Infarct size and post-infarct inflammation determine the risk of cardiac rupture in mice. Int J Cardiol (2009) 1.03
ERK and p38 MAPK signaling pathways negatively regulate CIITA gene expression in dendritic cells and macrophages. J Immunol (2006) 1.02
Competing ligands stabilize alternate conformations of the energy coupling motif of a TonB-dependent outer membrane transporter. Proc Natl Acad Sci U S A (2003) 1.02
Solute effects on spin labels at an aqueous-exposed site in the flap region of HIV-1 protease. J Phys Chem B (2009) 1.02
Structural and dynamic studies of the transcription factor ERG reveal DNA binding is allosterically autoinhibited. Proc Natl Acad Sci U S A (2013) 1.02
Evaluation of the humoral and cellular immune responses elicited by the live attenuated and inactivated influenza vaccines and their roles in heterologous protection in ferrets. J Infect Dis (2013) 1.01
Flexible fiber nanogenerator with 209 V output voltage directly powers a light-emitting diode. Nano Lett (2012) 1.00
Protective effect of resveratrol against kainate-induced temporal lobe epilepsy in rats. Neurochem Res (2009) 0.99
Mouse-adapted H9N2 influenza A virus PB2 protein M147L and E627K mutations are critical for high virulence. PLoS One (2012) 0.99
Substrate-dependent transmembrane signaling in TonB-dependent transporters is not conserved. Proc Natl Acad Sci U S A (2007) 0.99
Conformation and membrane position of the region linking the two C2 domains in synaptotagmin 1 by site-directed spin labeling. Biochemistry (2008) 0.98
Preliminary X-ray characterization and phasing of a type II cohesin domain from the cellulosome of Acetivibrio cellulolyticus. Acta Crystallogr D Biol Crystallogr (2003) 0.98
Synaptotagmin 1 and SNAREs form a complex that is structurally heterogeneous. J Mol Biol (2010) 0.98
Archaeal JAB1/MPN/MOV34 metalloenzyme (HvJAMM1) cleaves ubiquitin-like small archaeal modifier proteins (SAMPs) from protein-conjugates. Mol Microbiol (2012) 0.98
Osmolytes modulate conformational exchange in solvent-exposed regions of membrane proteins. Protein Sci (2010) 0.97
A biophysical perspective on the cellulosome: new opportunities for biomass conversion. Curr Opin Biotechnol (2008) 0.97
The expression of CXCL12 and CXCR4 in gastric cancer and their correlation to lymph node metastasis. Med Oncol (2011) 0.96
Molecular origin of electron paramagnetic resonance line shapes on β-barrel membrane proteins: the local solvation environment modulates spin-label configuration. Biochemistry (2011) 0.96
Relaxin remodels fibrotic healing following myocardial infarction. Lab Invest (2011) 0.96
Synaptotagmin 1 modulates lipid acyl chain order in lipid bilayers by demixing phosphatidylserine. J Biol Chem (2011) 0.95
Differential effects of triterpene glycosides, frondoside A and cucumarioside A2-2 isolated from sea cucumbers on caspase activation and apoptosis of human leukemia cells. FEBS Lett (2009) 0.95
Serum BDNF levels and weight gain in schizophrenic patients on long-term treatment with antipsychotics. J Psychiatr Res (2006) 0.94
Arginase II knockout mouse displays a hypertensive phenotype despite a decreased vasoconstrictory profile. Hypertension (2009) 0.94
Gambogenic acid inhibits proliferation of A549 cells through apoptosis-inducing and cell cycle arresting. Biol Pharm Bull (2010) 0.93
Perfluorooctyl bromide has limited membrane solubility and is located at the bilayer center. Locating small molecules in lipid bilayers through paramagnetic enhancements of NMR relaxation. J Med Chem (2002) 0.93
Elucidating a relationship between conformational sampling and drug resistance in HIV-1 protease. Biochemistry (2013) 0.92
Membrane hydrocarbon thickness modulates the dynamics of a membrane transport protein. Biophys J (2008) 0.92
A study of circulating gliadin antibodies in schizophrenia among a Chinese population. Schizophr Bull (2010) 0.92
H5N1 vaccine-specific B cell responses in ferrets primed with live attenuated seasonal influenza vaccines. PLoS One (2009) 0.91
An association study between polymorphisms in three genes of 14-3-3 (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein) family and paranoid schizophrenia in northern Chinese population. Eur Psychiatry (2004) 0.91
Pulsed EPR distance measurements in soluble proteins by site-directed spin labeling (SDSL). Curr Protoc Protein Sci (2013) 0.90
Mapping the spatio-temporal pattern of the mammalian target of rapamycin (mTOR) activation in temporal lobe epilepsy. PLoS One (2012) 0.90
Membrane mimetic environments alter the conformation of the outer membrane protein BtuB. J Am Chem Soc (2003) 0.90
Interleukin-6 family of cytokines mediates isoproterenol-induced delayed STAT3 activation in mouse heart. J Biol Chem (2003) 0.90
Effects of MAOA promoter methylation on susceptibility to paranoid schizophrenia. Hum Genet (2011) 0.89
Naturally occurring mutations in the PA gene are key contributors to increased virulence of pandemic H1N1/09 influenza virus in mice. J Virol (2014) 0.89
Evidence of epistasis between the catechol-O-methyltransferase and aldehyde dehydrogenase 3B1 genes in paranoid schizophrenia. Biol Psychiatry (2009) 0.89
The SNARE motif of synaptobrevin exhibits an aqueous-interfacial partitioning that is modulated by membrane curvature. Biochemistry (2014) 0.88
The unique binding mode of cellulosomal CBM4 from Clostridium thermocellum cellobiohydrolase A. J Mol Biol (2010) 0.88
Genetic association of the interaction between the BDNF and GSK3B genes and major depressive disorder in a Chinese population. J Neural Transm (Vienna) (2009) 0.88
In situ imaging of single carbohydrate-binding modules on cellulose microfibrils. J Phys Chem B (2010) 0.88
Correlating conformational shift induction with altered inhibitor potency in a multidrug resistant HIV-1 protease variant. Biochemistry (2012) 0.88
The combined effect of norepinephrine transporter gene and negative life events in major depression of Chinese Han population. J Neural Transm (Vienna) (2008) 0.88
Allosteric control of syntaxin 1a by Munc18-1: characterization of the open and closed conformations of syntaxin. Biophys J (2013) 0.87
Pulmonary immunity to viral infection: adenovirus infection of lung dendritic cells renders T cells nonresponsive to interleukin-2. J Virol (2006) 0.87
Increased JNK1 signaling pathway is responsible for ABCG2-mediated multidrug resistance in human colon cancer. PLoS One (2012) 0.87
Partitioning of synaptotagmin I C2 domains between liquid-ordered and liquid-disordered inner leaflet lipid phases. Biochemistry (2011) 0.87
Rs1076560, a functional variant of the dopamine D2 receptor gene, confers risk of schizophrenia in Han Chinese. Neurosci Lett (2012) 0.86
Structure of a fibronectin type III-like module from Clostridium thermocellum. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.86