Published in Am J Respir Crit Care Med on February 02, 2006
Environmental epigenetics and asthma: current concepts and call for studies. Am J Respir Crit Care Med (2008) 2.26
Oxidants and the pathogenesis of lung diseases. J Allergy Clin Immunol (2008) 1.91
Outdoor air pollution and asthma. Lancet (2014) 1.64
Relationship between air pollution, lung function and asthma in adolescents. Thorax (2007) 1.44
Interactions between glutathione S-transferase P1, tumor necrosis factor, and traffic-related air pollution for development of childhood allergic disease. Environ Health Perspect (2008) 1.40
Signal transduction pathways of tumor necrosis factor--mediated lung injury induced by ozone in mice. Am J Respir Crit Care Med (2007) 1.37
Unifying candidate gene and GWAS Approaches in Asthma. PLoS One (2010) 1.36
Ozone, oxidant defense genes, and risk of asthma during adolescence. Am J Respir Crit Care Med (2007) 1.33
Gene-air pollution interactions in asthma. Proc Am Thorac Soc (2007) 1.27
Traffic-related air pollution, oxidative stress genes, and asthma (ECHRS). Environ Health Perspect (2009) 1.18
Outdoor air pollution, genetic susceptibility, and asthma management: opportunities for intervention to reduce the burden of asthma. Pediatrics (2009) 1.11
Parental smoking modifies the relation between genetic variation in tumor necrosis factor-alpha (TNF) and childhood asthma. Environ Health Perspect (2007) 1.10
IL10 polymorphisms are associated with airflow obstruction in severe alpha1-antitrypsin deficiency. Am J Respir Cell Mol Biol (2007) 1.08
Chronic effects of air pollution on respiratory health in Southern California children: findings from the Southern California Children's Health Study. J Thorac Dis (2015) 1.06
Allergic diseases and air pollution. Asia Pac Allergy (2013) 1.03
Roles of arginase variants, atopy, and ozone in childhood asthma. J Allergy Clin Immunol (2009) 1.03
Toxicogenetics: population-based testing of drug and chemical safety in mouse models. Pharmacogenomics (2010) 1.02
NAD(P)H quinone oxidoreductase 1 is essential for ozone-induced oxidative stress in mice and humans. Am J Respir Cell Mol Biol (2008) 0.99
Gene by environment interaction and ambient air pollution. Proc Am Thorac Soc (2010) 0.89
The role of oxidative stress in the pathogenesis of asthma. Allergy Asthma Immunol Res (2010) 0.89
Gene-environment interactions in sarcoidosis: challenge and opportunity. Clin Dermatol (2007) 0.86
The -308 G/A polymorphism in TNF-α gene is associated with asthma risk: an update by meta-analysis. J Clin Immunol (2010) 0.83
TNF gene polymorphisms in cystic fibrosis patients: contribution to the disease progression. J Transl Med (2013) 0.80
Association study of genes associated to asthma in a specific environment, in an asthma familial collection located in a rural area influenced by different industries. Int J Environ Res Public Health (2012) 0.79
Joint analysis for integrating two related studies of different data types and different study designs using hierarchical modeling approaches. Hum Hered (2013) 0.77
Perinatal gene-gene and gene-environment interactions on IgE production and asthma development. Clin Dev Immunol (2012) 0.77
Gene-environment interaction from international cohorts: impact on development and evolution of occupational and environmental lung and airway disease. Semin Respir Crit Care Med (2015) 0.77
Can certain genotypes predispose to poor asthma control in children? A pharmacogenetic study of 9 candidate genes in children with difficult asthma. PLoS One (2013) 0.76
Interaction of intercellular adhesion molecule 1 (ICAM1) polymorphisms and environmental tobacco smoke on childhood asthma. Int J Environ Res Public Health (2014) 0.76
The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance. Crit Rev Biochem Mol Biol (1995) 10.39
Asthma in exercising children exposed to ozone: a cohort study. Lancet (2002) 5.84
A study of twelve Southern California communities with differing levels and types of air pollution. I. Prevalence of respiratory morbidity. Am J Respir Crit Care Med (1999) 3.71
A testing framework for identifying susceptibility genes in the presence of epistasis. Am J Hum Genet (2005) 3.69
Effect of glutathione-S-transferase M1 and P1 genotypes on xenobiotic enhancement of allergic responses: randomised, placebo-controlled crossover study. Lancet (2004) 3.40
A study of twelve Southern California communities with differing levels and types of air pollution. II. Effects on pulmonary function. Am J Respir Crit Care Med (1999) 3.18
Single base polymorphism in the human tumour necrosis factor alpha (TNF alpha) gene detectable by NcoI restriction of PCR product. Hum Mol Genet (1992) 3.12
Interleukin-4, -5, and -6 and tumor necrosis factor-alpha in normal and asthmatic airways: evidence for the human mast cell as a source of these cytokines. Am J Respir Cell Mol Biol (1994) 2.73
Macrophage metalloelastase mediates acute cigarette smoke-induced inflammation via tumor necrosis factor-alpha release. Am J Respir Crit Care Med (2003) 2.64
Health effects of exposure to environmental tobacco smoke. California Environmental Protection Agency. Tob Control (1997) 2.61
Genetic polymorphism of GSTM1 and antioxidant supplementation influence lung function in relation to ozone exposure in asthmatic children in Mexico City. Thorax (2004) 2.55
Effects of glutathione S-transferase M1, maternal smoking during pregnancy, and environmental tobacco smoke on asthma and wheezing in children. Am J Respir Crit Care Med (2002) 2.32
Linkage map of the human major histocompatibility complex including the tumor necrosis factor genes. Proc Natl Acad Sci U S A (1987) 2.31
Chemoprotection against cancer by phase 2 enzyme induction. Toxicol Lett (1995) 2.11
Diagnosing asthma by questionnaire in epidemiological surveys. Clin Exp Allergy (1992) 1.73
Tumor necrosis factor-alpha gene polymorphism in chronic bronchitis. Am J Respir Crit Care Med (1997) 1.63
Polymorphism at the glutathione S-transferase GSTP1 locus. A new marker for bronchial hyperresponsiveness and asthma. Am J Respir Crit Care Med (2000) 1.61
Glutathione S-transferase: genetics and role in toxicology. Toxicol Lett (2000) 1.59
A theoretical basis for investigating ambient air pollution and children's respiratory health. Environ Health Perspect (1999) 1.52
Glutathione S transferase deficiency and passive smoking increase childhood asthma. Thorax (2004) 1.49
Tumour necrosis factor haplotypes and asthma. Hum Mol Genet (1997) 1.48
Long-term ambient ozone concentration and the incidence of asthma in nonsmoking adults: the AHSMOG Study. Environ Res (1999) 1.37
Air pollution and allergy: you are what you breathe. Nat Immunol (2005) 1.32
Glutathione S-transferase P1 gene polymorphism and air pollution as interactive risk factors for childhood asthma. Clin Exp Allergy (2004) 1.32
Evidence for gene-environment interactions in a linkage study of asthma and smoking exposure. J Allergy Clin Immunol (2003) 1.27
Family-based association studies. J Natl Cancer Inst Monogr (1999) 1.22
Tumor necrosis factor receptor 2 contributes to ozone-induced airway hyperresponsiveness in mice. Am J Respir Crit Care Med (2001) 1.22
Tumour necrosis factor alpha: a potential mediator of asthma. Clin Exp Allergy (1995) 1.21
Air pollution in asthma: effect of pollutants on airway inflammation. Ann Allergy Asthma Immunol (2001) 1.21
Polymorphisms at the glutathione S-transferase, GSTP1 locus: a novel mechanism for susceptibility and development of atopic airway inflammation. Allergy (2000) 1.19
Side-stream cigarette smoke induces dose-response in systemic inflammatory cytokine production and oxidative stress. Exp Biol Med (Maywood) (2002) 1.16
Gene-environment interactions in asthma and other respiratory diseases. Annu Rev Med (2005) 1.15
Association of polymorphisms within the tumour necrosis factor (TNF) genes and childhood asthma. Clin Exp Allergy (1998) 1.14
Glutathione S-transferase genotypes and allergic responses to diisocyanate exposure. Pharmacogenetics (2001) 1.10
TNF-alpha induces the late-phase airway hyperresponsiveness and airway inflammation through cytosolic phospholipase A(2) activation. J Allergy Clin Immunol (2005) 1.10
Relation between tumour necrosis factor polymorphism TNFalpha-308 and risk of asthma. Eur J Hum Genet (2002) 1.07
Association of tumor necrosis factor-alpha polymorphisms and ozone-induced change in lung function. Am J Respir Crit Care Med (2004) 1.05
Breathing freely: the need for asthma research on gene-environment interactions. Am J Public Health (1999) 1.04
Association between TNFA polymorphism and the development of asthma in the Japanese population. Am J Respir Crit Care Med (2002) 1.02
Studies on the biological effects of ozone: 2. Induction of tumor necrosis factor (TNF-alpha) on human leucocytes. Lymphokine Cytokine Res (1991) 0.98
Association of the TNF-alpha-308 (G-->A) polymorphism with self-reported history of childhood asthma. Hum Genet (2000) 0.98
Association between - 308 tumour necrosis factor promoter polymorphism and bronchial hyperreactivity in asthma. Clin Exp Allergy (1999) 0.98
Prevalence of tumor necrosis factor-alpha and angiotensin converting enzyme polymorphisms in mild/moderate and fatal/near-fatal asthma. Am J Respir Crit Care Med (1999) 0.97
TNF-alpha production by eosinophils in upper airways inflammation (nasal polyposis). J Immunol (1994) 0.94
Extended haplotype in the tumor necrosis factor gene cluster is associated with asthma and asthma-related phenotypes. Am J Respir Crit Care Med (2005) 0.93
Ozone-induced inflammation assessed in sputum and bronchial lavage fluid from asthmatics: a new noninvasive tool in epidemiologic studies on air pollution and asthma. Free Radic Biol Med (1999) 0.93
Extended tumour necrosis factor/HLA-DR haplotypes and asthma in an Australian population sample. Thorax (1999) 0.88
Lack of association between adult asthma and the tumour necrosis factor alpha-308 polymorphism gene. Eur Respir J (2000) 0.87
Tumour necrosis factor gene polymorphisms and childhood wheezing. Eur Respir J (2005) 0.87
The association between tumor necrosis factor, HLA-DR alleles, and IgE-mediated asthma in Taiwanese adolescents. Allergy (2002) 0.86
Lack of association between atopic asthma and the tumor necrosis factor alpha-308 gene polymorphism in a Czech population. J Investig Allergol Clin Immunol (2002) 0.85
Atopic asthma and TNF-308 alleles: linkage disequilibrium and association analyses. Hum Immunol (2003) 0.85
Role of tumor necrosis factor alpha in asthma. Immunol Allergy Clin North Am (2004) 0.82
High-Density SNP genotyping defines 17 distinct haplotypes of the TNF block in the Caucasian population: implications for haplotype tagging. Hum Mutat (2004) 0.82
Production of TNF-alpha by peripheral blood mononuclear cells through activation of nuclear factor kappa B by specific allergen stimulation in patients with atopic asthma. Allergy Asthma Proc (2003) 0.79
Relevance of the selected cytokine release (TNF-alpha, IL-6, IFN-gamma, and IFN-alpha) to the exacerbation of bronchial asthma from airway mycotic infections. Predominant role of TFN-alpha? J Investig Allergol Clin Immunol (2002) 0.79
Asthma in exercising children exposed to ozone: a cohort study. Lancet (2002) 5.84
Exploiting gene-environment interaction to detect genetic associations. Hum Hered (2007) 5.63
Traffic, susceptibility, and childhood asthma. Environ Health Perspect (2006) 5.50
Prenatal tobacco smoke exposure affects global and gene-specific DNA methylation. Am J Respir Crit Care Med (2009) 4.44
Gene-environment interaction in genome-wide association studies. Am J Epidemiol (2008) 3.96
Obesity and the risk of newly diagnosed asthma in school-age children. Am J Epidemiol (2003) 3.87
A testing framework for identifying susceptibility genes in the presence of epistasis. Am J Hum Genet (2005) 3.69
Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. Nat Genet (2011) 3.68
Elevated biomarkers of inflammation are associated with reduced survival among breast cancer patients. J Clin Oncol (2009) 3.58
Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene. Am J Hum Genet (2009) 3.41
Physical activity levels before and after a diagnosis of breast carcinoma: the Health, Eating, Activity, and Lifestyle (HEAL) study. Cancer (2003) 3.25
Childhood incident asthma and traffic-related air pollution at home and school. Environ Health Perspect (2010) 3.24
Physical activity levels among breast cancer survivors. Med Sci Sports Exerc (2004) 2.88
Influence of pre- and postdiagnosis physical activity on mortality in breast cancer survivors: the health, eating, activity, and lifestyle study. J Clin Oncol (2008) 2.85
Health effects of the 2003 Southern California wildfires on children. Am J Respir Crit Care Med (2006) 2.81
Critical role of the stress chaperone GRP78/BiP in tumor proliferation, survival, and tumor angiogenesis in transgene-induced mammary tumor development. Cancer Res (2008) 2.81
5-year urinary and sexual outcomes after radical prostatectomy: results from the prostate cancer outcomes study. J Urol (2005) 2.72
A genome-wide association meta-analysis identifies new childhood obesity loci. Nat Genet (2012) 2.60
Aberrant promoter methylation in bronchial epithelium and sputum from current and former smokers. Cancer Res (2002) 2.56
Quality of life following localized prostate cancer treated initially with androgen deprivation therapy or no therapy. J Natl Cancer Inst (2002) 2.54
Childhood air pollutant exposure and carotid artery intima-media thickness in young adults. Circulation (2012) 2.51
Effects of glutathione S-transferase M1, maternal smoking during pregnancy, and environmental tobacco smoke on asthma and wheezing in children. Am J Respir Crit Care Med (2002) 2.32
Traffic-related air pollution and asthma onset in children: a prospective cohort study with individual exposure measurement. Environ Health Perspect (2008) 2.17
Birth outcomes and prenatal exposure to ozone, carbon monoxide, and particulate matter: results from the Children's Health Study. Environ Health Perspect (2005) 2.17
5-year urinary and sexual outcomes after radical prostatectomy: results from the Prostate Cancer Outcomes Study. J Urol (2008) 2.16
Microsomal epoxide hydrolase, glutathione S-transferase P1, traffic and childhood asthma. Thorax (2007) 2.10
Long-term epigenetic therapy with oral zebularine has minimal side effects and prevents intestinal tumors in mice. Cancer Prev Res (Phila) (2008) 2.04
Changes in body fat and weight after a breast cancer diagnosis: influence of demographic, prognostic, and lifestyle factors. J Clin Oncol (2005) 2.01
Recent evidence for adverse effects of residential proximity to traffic sources on asthma. Curr Opin Pulm Med (2008) 2.00
Effects of glutathione-S-transferase M1, T1, and P1 on childhood lung function growth. Am J Respir Crit Care Med (2002) 1.98
Maternal and grandmaternal smoking patterns are associated with early childhood asthma. Chest (2005) 1.98
The sex hormone system in carriers of BRCA1/2 mutations: a case-control study. Lancet Oncol (2013) 1.83
Gene promoter methylation in plasma and sputum increases with lung cancer risk. Clin Cancer Res (2005) 1.81
DNA methylation in the arginase-nitric oxide synthase pathway is associated with exhaled nitric oxide in children with asthma. Am J Respir Crit Care Med (2011) 1.79
Sample size requirements to detect gene-environment interactions in genome-wide association studies. Genet Epidemiol (2011) 1.78
Prospective study of air pollution and bronchitic symptoms in children with asthma. Am J Respir Crit Care Med (2003) 1.66
Air pollution exposure assessment for epidemiologic studies of pregnant women and children: lessons learned from the Centers for Children's Environmental Health and Disease Prevention Research. Environ Health Perspect (2005) 1.65
Correlates of circulating C-reactive protein and serum amyloid A concentrations in breast cancer survivors. Breast Cancer Res Treat (2008) 1.60
Cross-sectional and longitudinal comparisons of health-related quality of life between patients with prostate carcinoma and matched controls. Cancer (2004) 1.60
Triplet repeat mutation length gains correlate with cell-type specific vulnerability in Huntington disease brain. Hum Mol Genet (2007) 1.57
Relationship of obesity and physical activity with C-peptide, leptin, and insulin-like growth factors in breast cancer survivors. Cancer Epidemiol Biomarkers Prev (2005) 1.56
Native American ancestry affects the risk for gene methylation in the lungs of Hispanic smokers from New Mexico. Am J Respir Crit Care Med (2013) 1.54
Further replication studies of the EVE Consortium meta-analysis identifies 2 asthma risk loci in European Americans. J Allergy Clin Immunol (2012) 1.54
Enhanced RNA polymerase III-dependent transcription is required for oncogenic transformation. J Biol Chem (2008) 1.53
Regular smoking and asthma incidence in adolescents. Am J Respir Crit Care Med (2006) 1.49
Modeling the residential infiltration of outdoor PM(2.5) in the Multi-Ethnic Study of Atherosclerosis and Air Pollution (MESA Air). Environ Health Perspect (2012) 1.47
Relationship between air pollution, lung function and asthma in adolescents. Thorax (2007) 1.44
Transforming growth factor- 1 C-509T polymorphism, oxidant stress, and early-onset childhood asthma. Am J Respir Crit Care Med (2007) 1.44
Patient satisfaction with treatment decisions for clinically localized prostate carcinoma. Results from the Prostate Cancer Outcomes Study. Cancer (2003) 1.44
Effects of ethnicity, family income, and education on dietary intake among adolescents. Prev Med (2003) 1.38
Huntington disease expansion mutations in humans can occur before meiosis is completed. Proc Natl Acad Sci U S A (2003) 1.35
Breathless in Los Angeles: the exhausting search for clean air. Am J Public Health (2003) 1.34
Ozone, oxidant defense genes, and risk of asthma during adolescence. Am J Respir Crit Care Med (2007) 1.33
Invited commentary: GE-Whiz! Ratcheting gene-environment studies up to the whole genome and the whole exposome. Am J Epidemiol (2011) 1.32
Racial differences in initial treatment for clinically localized prostate cancer. Results from the prostate cancer outcomes study. J Gen Intern Med (2003) 1.30
Does mammographic density reflect ethnic differences in breast cancer incidence rates? Am J Epidemiol (2004) 1.30
TSLP polymorphisms are associated with asthma in a sex-specific fashion. Allergy (2010) 1.29
Childhood sun exposure influences risk of multiple sclerosis in monozygotic twins. Neurology (2007) 1.29
Ambient endotoxin concentrations in PM10 from Southern California. Environ Health Perspect (2004) 1.28
Exhaled nitric oxide in a population-based study of southern California schoolchildren. Respir Res (2009) 1.28
Effects of misattribution in assigning cause of death on prostate cancer mortality rates. Ann Epidemiol (2003) 1.25
Associations of weight, weight change, and body mass with breast cancer risk in Hispanic and non-Hispanic white women. Ann Epidemiol (2002) 1.23
Double-strand break damage and associated DNA repair genes predispose smokers to gene methylation. Cancer Res (2008) 1.22
Endogenous and exogenous sex steroid hormones and asthma and wheeze in young women. J Allergy Clin Immunol (2006) 1.21
Genetic and epigenetic variations in inducible nitric oxide synthase promoter, particulate pollution, and exhaled nitric oxide levels in children. J Allergy Clin Immunol (2011) 1.21
Parental stress increases the detrimental effect of traffic exposure on children's lung function. Am J Respir Crit Care Med (2011) 1.19
Children's lung function and antioxidant vitamin, fruit, juice, and vegetable intake. Am J Epidemiol (2003) 1.19
IL-6 levels and genotype are associated with risk of young adult Hodgkin lymphoma. Blood (2003) 1.18
Regression models for linkage: issues of traits, covariates, heterogeneity, and interaction. Hum Hered (2003) 1.15
Multivitamins, folate, and green vegetables protect against gene promoter methylation in the aerodigestive tract of smokers. Cancer Res (2010) 1.14
Cell-nonautonomous induction of ovarian and uterine serous cystadenomas in mice lacking a functional Brca1 in ovarian granulosa cells. Curr Biol (2005) 1.14
Differential twin concordance for multiple sclerosis by latitude of birthplace. Ann Neurol (2006) 1.14
Glutathione S-transferase P1, maternal smoking, and asthma in children: a haplotype-based analysis. Environ Health Perspect (2008) 1.13
Relationships of online exhaled, offline exhaled, and ambient nitric oxide in an epidemiologic survey of schoolchildren. J Expo Sci Environ Epidemiol (2008) 1.13
Physical activity, body mass index, and mammographic density in postmenopausal breast cancer survivors. J Clin Oncol (2007) 1.13
Predictors of intra-community variation in air quality. J Expo Sci Environ Epidemiol (2012) 1.12
Air pollution and children--an unhealthy mix. N Engl J Med (2006) 1.11
Promoter hypermethylation of the O6-methylguanine-DNA methyltransferase gene: more common in lung adenocarcinomas from never-smokers than smokers and associated with tumor progression. Cancer Res (2003) 1.10
Residential traffic-related pollution exposures and exhaled nitric oxide in the children's health study. Environ Health Perspect (2011) 1.09
The A/G allele of rs16906252 predicts for MGMT methylation and is selectively silenced in premalignant lesions from smokers and in lung adenocarcinomas. Clin Cancer Res (2011) 1.09
Increased expression of TATA-binding protein, the central transcription factor, can contribute to oncogenesis. Mol Cell Biol (2003) 1.09