Published in Nature on June 20, 1991
Positionally cloned human disease genes: patterns of evolutionary conservation and functional motifs. Proc Natl Acad Sci U S A (1997) 4.40
Quinolone resistance mutations in the DNA gyrase gyrA and gyrB genes of Staphylococcus aureus. Antimicrob Agents Chemother (1994) 3.96
Nucleotide sequence of the Staphylococcus aureus gyrB-gyrA locus encoding the DNA gyrase A and B proteins. J Bacteriol (1992) 3.95
Type IIA topoisomerase inhibition by a new class of antibacterial agents. Nature (2010) 3.58
In vivo function of Hsp90 is dependent on ATP binding and ATP hydrolysis. J Cell Biol (1998) 3.38
Structures of GRP94-nucleotide complexes reveal mechanistic differences between the hsp90 chaperones. Mol Cell (2007) 3.29
The ATPase cycle of Hsp90 drives a molecular 'clamp' via transient dimerization of the N-terminal domains. EMBO J (2000) 3.00
The gene encoding a major component of the lateral elements of synaptonemal complexes of the rat is related to X-linked lymphocyte-regulated genes. Mol Cell Biol (1994) 2.92
The nature of inhibition of DNA gyrase by the coumarins and the cyclothialidines revealed by X-ray crystallography. EMBO J (1996) 2.60
Ser-127-to-Leu substitution in the DNA gyrase B subunit of Streptococcus pneumoniae is implicated in novobiocin resistance. J Bacteriol (1995) 2.06
Mutations in topoisomerase IV and DNA gyrase of Staphylococcus aureus: novel pleiotropic effects on quinolone and coumarin activity. Antimicrob Agents Chemother (1998) 1.97
The C-terminal domain of DNA gyrase A adopts a DNA-bending beta-pinwheel fold. Proc Natl Acad Sci U S A (2004) 1.93
The structure of DNA-bound human topoisomerase II alpha: conformational mechanisms for coordinating inter-subunit interactions with DNA cleavage. J Mol Biol (2012) 1.87
Exploiting bacterial DNA gyrase as a drug target: current state and perspectives. Appl Microbiol Biotechnol (2011) 1.85
DNA transport by a type II topoisomerase: direct evidence for a two-gate mechanism. Proc Natl Acad Sci U S A (1996) 1.77
gyrB mutations in coumermycin A1-resistant Borrelia burgdorferi. J Bacteriol (1994) 1.74
A model for the mechanism of strand passage by DNA gyrase. Proc Natl Acad Sci U S A (1999) 1.74
Structure and function of type II DNA topoisomerases. Biochem J (1994) 1.73
Agrobacterium tumefaciens VirB11 protein requires a consensus nucleotide-binding site for function in virulence. J Bacteriol (1995) 1.72
Cloning, sequencing, and expression of the DNA gyrase genes from Staphylococcus aureus. J Bacteriol (1993) 1.72
Structural basis for recruitment of the ATPase activator Aha1 to the Hsp90 chaperone machinery. EMBO J (2004) 1.63
Topoisomerase II drives DNA transport by hydrolyzing one ATP. Proc Natl Acad Sci U S A (1999) 1.57
Distinct structural mechanisms for inhibition of pyruvate dehydrogenase kinase isoforms by AZD7545, dichloroacetate, and radicicol. Structure (2007) 1.49
Structural similarities between topoisomerases that cleave one or both DNA strands. Proc Natl Acad Sci U S A (1998) 1.47
Structure of the topoisomerase II ATPase region and its mechanism of inhibition by the chemotherapeutic agent ICRF-187. Proc Natl Acad Sci U S A (2003) 1.44
Functional studies on the candidate ATPase domains of Saccharomyces cerevisiae MutLalpha. Mol Cell Biol (2000) 1.42
Quinolone-binding pocket of DNA gyrase: role of GyrB. Antimicrob Agents Chemother (2002) 1.38
Proteolysis patterns of epitopically labeled yeast DNA topoisomerase II suggest an allosteric transition in the enzyme induced by ATP binding. Proc Natl Acad Sci U S A (1991) 1.36
Structure and function of the N-terminal 40 kDa fragment of human PMS2: a monomeric GHL ATPase. EMBO J (2001) 1.35
Dual targeting of DNA gyrase and topoisomerase IV: target interactions of garenoxacin (BMS-284756, T-3811ME), a new desfluoroquinolone. Antimicrob Agents Chemother (2002) 1.34
Crystal structure of pyruvate dehydrogenase kinase 3 bound to lipoyl domain 2 of human pyruvate dehydrogenase complex. EMBO J (2005) 1.31
Evidence for a conformational change in the DNA gyrase-DNA complex from hydroxyl radical footprinting. Nucleic Acids Res (1994) 1.27
Probing the differential interactions of quinazolinedione PD 0305970 and quinolones with gyrase and topoisomerase IV. Antimicrob Agents Chemother (2009) 1.24
Identification of the coumermycin A(1) biosynthetic gene cluster of Streptomyces rishiriensis DSM 40489. Antimicrob Agents Chemother (2000) 1.22
Probing the role of the ATP-operated clamp in the strand-passage reaction of DNA gyrase. Nucleic Acids Res (1996) 1.18
Structure of the topoisomerase VI-B subunit: implications for type II topoisomerase mechanism and evolution. EMBO J (2003) 1.18
Crystal structures of Escherichia coli topoisomerase IV ParE subunit (24 and 43 kilodaltons): a single residue dictates differences in novobiocin potency against topoisomerase IV and DNA gyrase. Antimicrob Agents Chemother (2004) 1.17
Simocyclinone D8, an inhibitor of DNA gyrase with a novel mode of action. Antimicrob Agents Chemother (2005) 1.16
Functional dissection of the phosphorylated termini of fission yeast DNA topoisomerase II. J Cell Biol (1992) 1.16
Pyruvate dehydrogenase kinase-4 structures reveal a metastable open conformation fostering robust core-free basal activity. J Biol Chem (2008) 1.10
Bioflavonoids as poisons of human topoisomerase II alpha and II beta. Biochemistry (2007) 1.10
Structure of rat BCKD kinase: nucleotide-induced domain communication in a mitochondrial protein kinase. Proc Natl Acad Sci U S A (2001) 1.10
Structure of pyruvate dehydrogenase kinase. Novel folding pattern for a serine protein kinase. J Biol Chem (2001) 1.10
A domain insertion in Escherichia coli GyrB adopts a novel fold that plays a critical role in gyrase function. Nucleic Acids Res (2010) 1.09
Structure of a topoisomerase II-DNA-nucleotide complex reveals a new control mechanism for ATPase activity. Nat Struct Mol Biol (2012) 1.09
Alteration of Escherichia coli topoisomerase IV to novobiocin resistance. Antimicrob Agents Chemother (2003) 1.09
Structure of adeno-associated virus type 2 Rep40-ADP complex: insight into nucleotide recognition and catalysis by superfamily 3 helicases. Proc Natl Acad Sci U S A (2004) 1.08
Structural frameworks for considering microbial protein- and nucleic acid-dependent motor ATPases. Mol Microbiol (2008) 1.07
GyrB mutations in Staphylococcus aureus strains resistant to cyclothialidine, coumermycin, and novobiocin. Antimicrob Agents Chemother (1996) 1.07
The ancestral role of ATP hydrolysis in type II topoisomerases: prevention of DNA double-strand breaks. Nucleic Acids Res (2011) 1.07
Active-site residues of Escherichia coli DNA gyrase required in coupling ATP hydrolysis to DNA supercoiling and amino acid substitutions leading to novobiocin resistance. Antimicrob Agents Chemother (2003) 1.05
Accumulation of mutations in both gyrB and parE genes is associated with high-level resistance to novobiocin in Staphylococcus aureus. Antimicrob Agents Chemother (2005) 1.05
Analysis of conditional mutations in the Saccharomyces cerevisiae MLH1 gene in mismatch repair and in meiotic crossing over. Genetics (2002) 1.05
The key DNA-binding residues in the C-terminal domain of Mycobacterium tuberculosis DNA gyrase A subunit (GyrA). Nucleic Acids Res (2006) 1.03
Crystal structure of DNA gyrase B' domain sheds lights on the mechanism for T-segment navigation. Nucleic Acids Res (2009) 1.03
Sequencing analysis reveals a unique gene organization in the gyrB region of Mycoplasma hominis. J Bacteriol (1994) 1.03
The DNA-gate of Bacillus subtilis gyrase is predominantly in the closed conformation during the DNA supercoiling reaction. Proc Natl Acad Sci U S A (2009) 1.02
Coupling between ATP binding and DNA cleavage by DNA topoisomerase II: A unifying kinetic and structural mechanism. J Biol Chem (2008) 1.02
Discovery of novel DNA gyrase inhibitors by high-throughput virtual screening. Antimicrob Agents Chemother (2007) 1.02
Analysis of functional domain organization in DNA topoisomerase II from humans and Saccharomyces cerevisiae. Mol Cell Biol (1996) 1.00
DNA-induced narrowing of the gyrase N-gate coordinates T-segment capture and strand passage. Proc Natl Acad Sci U S A (2011) 1.00
Quinolone mode of action--new aspects. Drugs (1993) 0.99
The role of DNA bending in type IIA topoisomerase function. Nucleic Acids Res (2013) 0.98
New mutation in parE in a pneumococcal in vitro mutant resistant to fluoroquinolones. Antimicrob Agents Chemother (2001) 0.98
The use of divalent metal ions by type II topoisomerases. Metallomics (2010) 0.98
Alleles of the yeast Pms1 mismatch-repair gene that differentially affect recombination- and replication-related processes. Genetics (2002) 0.97
Mechanisms for defining supercoiling set point of DNA gyrase orthologs: I. A nonconserved acidic C-terminal tail modulates Escherichia coli gyrase activity. J Biol Chem (2012) 0.97
Evidence that pyruvate dehydrogenase kinase belongs to the ATPase/kinase superfamily. Biochem J (1999) 0.96
Quinolone resistance mutations in the GrlB protein of Staphylococcus aureus. Antimicrob Agents Chemother (1998) 0.95
Molecular characterization of the Salmonella typhimurium parE gene. Nucleic Acids Res (1993) 0.95
Distribution of gyrase and topoisomerase IV on bacterial nucleoid: implications for nucleoid organization. Nucleic Acids Res (2006) 0.91
Construction and characterization of mutations at codon 751 of the Escherichia coli gyrB gene that confer resistance to the antimicrobial peptide microcin B17 and alter the activity of DNA gyrase. J Bacteriol (2001) 0.91
An Escherichia coli DNA topoisomerase I mutant has a compensatory mutation that alters two residues between functional domains of the DNA gyrase A protein. J Bacteriol (1992) 0.90
Solution structures of DNA-bound gyrase. Nucleic Acids Res (2010) 0.90
Guiding strand passage: DNA-induced movement of the gyrase C-terminal domains defines an early step in the supercoiling cycle. Nucleic Acids Res (2011) 0.89
Mutations in Bartonella bacilliformis gyrB confer resistance to coumermycin A1. Antimicrob Agents Chemother (1998) 0.89
Pyrrolamide DNA gyrase inhibitors: fragment-based nuclear magnetic resonance screening to identify antibacterial agents. Antimicrob Agents Chemother (2011) 0.88
Structural basis for topoisomerase VI inhibition by the anti-Hsp90 drug radicicol. Nucleic Acids Res (2006) 0.88
Mechanism of inhibition of DNA gyrase by cyclothialidine, a novel DNA gyrase inhibitor. Antimicrob Agents Chemother (1994) 0.88
Intradimerically tethered DNA topoisomerase II is catalytically active in DNA transport. Proc Natl Acad Sci U S A (1996) 0.87
Protein footprinting at cysteines: probing ATP-modulated contacts in cysteine-substitution mutants of yeast DNA topoisomerase II. Proc Natl Acad Sci U S A (1999) 0.86
DNA gyrase can cleave short DNA fragments in the presence of quinolone drugs. Nucleic Acids Res (1997) 0.86
Structure and conformational changes of DNA topoisomerase II visualized by electron microscopy. Proc Natl Acad Sci U S A (1996) 0.85
Temperature-sensitive suppressor mutations of the Escherichia coli DNA gyrase B protein. Protein Sci (2000) 0.85
DNA gyrase from the albicidin producer Xanthomonas albilineans has multiple-antibiotic-resistance and unusual enzymatic properties. Antimicrob Agents Chemother (2008) 0.84
Mitochondrial Hsp90 is a ligand-activated molecular chaperone coupling ATP binding to dimer closure through a coiled-coil intermediate. Proc Natl Acad Sci U S A (2016) 0.84
Mass spectrometric characterization of a three-enzyme tandem reaction for assembly and modification of the novobiocin skeleton. Proc Natl Acad Sci U S A (2004) 0.83
The naphthoquinone diospyrin is an inhibitor of DNA gyrase with a novel mechanism of action. J Biol Chem (2012) 0.83
The GyrA-box determines the geometry of DNA bound to gyrase and couples DNA binding to the nucleotide cycle. Nucleic Acids Res (2012) 0.83
Backbone resonance assignment of the N-terminal 24 kDa fragment of the gyrase B subunit from S. aureus complexed with novobiocin. J Biomol NMR (2000) 0.82
Characterization of the ATPase activity of topoisomerase II from Leishmania donovani and identification of residues conferring resistance to etoposide. Biochem J (2005) 0.82
Structure of the N-terminal Gyrase B fragment in complex with ADP⋅Pi reveals rigid-body motion induced by ATP hydrolysis. PLoS One (2014) 0.82
A unique 45-amino-acid region in the toprim domain of Plasmodium falciparum gyrase B is essential for its activity. Eukaryot Cell (2009) 0.81
Arabidopsis thaliana GYRB3 does not encode a DNA gyrase subunit. PLoS One (2010) 0.81
Characterisation of the DNA-dependent ATPase activity of human DNA topoisomerase IIbeta: mutation of Ser165 in the ATPase domain reduces the ATPase activity and abolishes the in vivo complementation ability. Nucleic Acids Res (2002) 0.80
Mode of action of GR122222X, a novel inhibitor of bacterial DNA gyrase. Antimicrob Agents Chemother (1996) 0.80
Mechanisms of activation of phosphoenolpyruvate carboxykinase from Escherichia coli by Ca2+ and of desensitization by trypsin. J Bacteriol (2003) 0.79
Dissection of the bacteriophage Mu strong gyrase site (SGS): significance of the SGS right arm in Mu biology and DNA gyrase mechanism. J Bacteriol (2006) 0.79
3D-QSAR and docking studies of flavonoids as potent Escherichia coli inhibitors. Sci Rep (2016) 0.79
The acidic C-terminal tail of the GyrA subunit moderates the DNA supercoiling activity of Bacillus subtilis gyrase. J Biol Chem (2014) 0.79
Refinement of macromolecular structures by the maximum-likelihood method. Acta Crystallogr D Biol Crystallogr (1997) 137.43
Efficient anisotropic refinement of macromolecular structures using FFT. Acta Crystallogr D Biol Crystallogr (1999) 15.91
Incorporation of prior phase information strengthens maximum-likelihood structure refinement. Acta Crystallogr D Biol Crystallogr (1998) 6.47
Glycosyltransferases: structures, functions, and mechanisms. Annu Rev Biochem (2008) 6.06
A classification of nucleotide-diphospho-sugar glycosyltransferases based on amino acid sequence similarities. Biochem J (1997) 5.86
DNA gyrase: structure and function. Crit Rev Biochem Mol Biol (1991) 5.25
Crystal structure of the breakage-reunion domain of DNA gyrase. Nature (1997) 4.10
Nomenclature for sugar-binding subsites in glycosyl hydrolases. Biochem J (1997) 3.82
A serine protease triad forms the catalytic centre of a triacylglycerol lipase. Nature (1990) 3.73
A single point mutation in the DNA gyrase A protein greatly reduces binding of fluoroquinolones to the gyrase-DNA complex. Antimicrob Agents Chemother (1993) 3.43
The structure of 2Zn pig insulin crystals at 1.5 A resolution. Philos Trans R Soc Lond B Biol Sci (1988) 3.30
A protein catalytic framework with an N-terminal nucleophile is capable of self-activation. Nature (1995) 3.30
Preinfarction angina as a predictor of more rapid coronary thrombolysis in patients with acute myocardial infarction. N Engl J Med (1996) 3.21
A modified ACORN to solve protein structures at resolutions of 1.7 A or better. Acta Crystallogr D Biol Crystallogr (2005) 2.95
Bowel function measurements of individuals with different eating patterns. Gut (1986) 2.92
Novel quinolone resistance mutations of the Escherichia coli DNA gyrase A protein: enzymatic analysis of the mutant proteins. Antimicrob Agents Chemother (1991) 2.82
The 43-kilodalton N-terminal fragment of the DNA gyrase B protein hydrolyzes ATP and binds coumarin drugs. Biochemistry (1993) 2.79
The nature of inhibition of DNA gyrase by the coumarins and the cyclothialidines revealed by X-ray crystallography. EMBO J (1996) 2.60
Tryptic fragments of the Escherichia coli DNA gyrase A protein. J Biol Chem (1989) 2.56
The structure of trp RNA-binding attenuation protein. Nature (1995) 2.55
The DNA dependence of the ATPase activity of DNA gyrase. J Biol Chem (1984) 2.51
Catalysis by hen egg-white lysozyme proceeds via a covalent intermediate. Nature (2001) 2.51
Structure of the nucleotide-diphospho-sugar transferase, SpsA from Bacillus subtilis, in native and nucleotide-complexed forms. Biochemistry (1999) 2.43
Central nervous pathways mediating angina pectoris. Lancet (1994) 2.38
Mechanistic aspects of DNA topoisomerases. Adv Protein Chem (1986) 2.35
Structure of the trp RNA-binding attenuation protein, TRAP, bound to RNA. Nature (1999) 2.35
Atomic positions in rhombohedral 2-zinc insulin crystals. Nature (1971) 2.31
gyrB mutations which confer coumarin resistance also affect DNA supercoiling and ATP hydrolysis by Escherichia coli DNA gyrase. Mol Microbiol (1992) 2.19
Penicillin acylase has a single-amino-acid catalytic centre. Nature (1995) 2.18
Reduced coronary vasodilator function in infarcted and normal myocardium after myocardial infarction. N Engl J Med (1994) 2.10
A census of carbohydrate-active enzymes in the genome of Arabidopsis thaliana. Plant Mol Biol (2001) 2.08
The structural basis of sequence-independent peptide binding by OppA protein. Science (1994) 2.05
Tumour necrosis factor and inducible nitric oxide synthase in dilated cardiomyopathy. Lancet (1996) 1.95
Effect of intracoronary serotonin on coronary vessels in patients with stable angina and patients with variant angina. N Engl J Med (1991) 1.87
Biodegradation of explosives by transgenic plants expressing pentaerythritol tetranitrate reductase. Nat Biotechnol (1999) 1.86
The X6 "thermostabilizing" domains of xylanases are carbohydrate-binding modules: structure and biochemistry of the Clostridium thermocellum X6b domain. Biochemistry (2000) 1.84
Structure of insulin in 4-zinc insulin. Nature (1976) 1.78
Structure of human lactoferrin at 3.2-A resolution. Proc Natl Acad Sci U S A (1987) 1.76
Interaction between DNA gyrase and quinolones: effects of alanine mutations at GyrA subunit residues Ser(83) and Asp(87). Antimicrob Agents Chemother (2001) 1.76
A model for the mechanism of strand passage by DNA gyrase. Proc Natl Acad Sci U S A (1999) 1.74
Effect of inhibition of nitric oxide synthesis on epicardial coronary artery caliber and coronary blood flow in humans. Circulation (1993) 1.74
The C-terminal domain of the Escherichia coli DNA gyrase A subunit is a DNA-binding protein. Nucleic Acids Res (1991) 1.74
The antibiotic microcin B17 is a DNA gyrase poison: characterisation of the mode of inhibition. J Mol Biol (2001) 1.74
Crystal structure of the type-2 Cu depleted laccase from Coprinus cinereus at 2.2 A resolution. Nat Struct Biol (1998) 1.70
Conversion of DNA gyrase into a conventional type II topoisomerase. Proc Natl Acad Sci U S A (1996) 1.70
Stress, social support and health-related behavior: a study of smoking, alcohol consumption and physical exercise. J Psychosom Res (1996) 1.70
Phenol stabilizes more helix in a new symmetrical zinc insulin hexamer. Nature (1989) 1.69
Glycoside hydrolases and glycosyltransferases. Families, modules, and implications for genomics. Plant Physiol (2000) 1.67
Cloning of the DNA gyrase genes under tac promoter control: overproduction of the gyrase A and B proteins. Gene (1990) 1.65
B protein of bacteriophage mu is an ATPase that preferentially stimulates intermolecular DNA strand transfer. Proc Natl Acad Sci U S A (1987) 1.64
Monomeric insulins obtained by protein engineering and their medical implications. Nature (1988) 1.62
Crystal structure of GerE, the ultimate transcriptional regulator of spore formation in Bacillus subtilis. J Mol Biol (2001) 1.62
Validation of a technique for studying functional adaptation of the mouse ulna in response to mechanical loading. Bone (2002) 1.59
Crystal structure of a suicidal DNA repair protein: the Ada O6-methylguanine-DNA methyltransferase from E. coli. EMBO J (1994) 1.58
The crystal structure of human rac1, a member of the rho-family complexed with a GTP analogue. Nat Struct Biol (1997) 1.58
Structure of a ternary complex of an allosteric lactate dehydrogenase from Bacillus stearothermophilus at 2.5 A resolution. J Mol Biol (1992) 1.54
Complications of carbenoxolone therapy. Br Med J (1974) 1.54
Effect of theophylline on exercise-induced myocardial ischaemia. Lancet (1989) 1.52
Enzymatic ketonization of 2-hydroxymuconate: specificity and mechanism investigated by the crystal structures of two isomerases. Biochemistry (1996) 1.52
Molecular structure of a new family of ribonucleases. Nature (1982) 1.52
The structure of the cofactor-binding fragment of the LysR family member, CysB: a familiar fold with a surprising subunit arrangement. Structure (1997) 1.50
The complex of DNA gyrase and quinolone drugs on DNA forms a barrier to the T7 DNA polymerase replication complex. J Mol Biol (2000) 1.50
The crystal structure of a cyanogenic beta-glucosidase from white clover, a family 1 glycosyl hydrolase. Structure (1995) 1.49
Determination of interspin distances between spin labels attached to insulin: comparison of electron paramagnetic resonance data with the X-ray structure. Biophys J (1997) 1.48
Structure of the DNA gyrase-DNA complex as revealed by transient electric dichroism. J Mol Biol (1987) 1.47
Crystal structure of the catalytic domain of a bacterial cellulase belonging to family 5. Structure (1995) 1.46
Structure of the pig insulin dimer in the cubic crystal. Acta Crystallogr B (1991) 1.45
Identifying the catalytic residue of the ATPase reaction of DNA gyrase. Proc Natl Acad Sci U S A (1993) 1.44
DNA gyrase can supercoil DNA circles as small as 174 base pairs. EMBO J (1989) 1.44
Tuberculous pericarditis with rapid progression to constriction. Prompt diagnosis and treatment are needed. BMJ (1993) 1.43
11-fold symmetry of the trp RNA-binding attenuation protein (TRAP) from Bacillus subtilis determined by X-ray analysis. J Mol Biol (1994) 1.42
Structural stability in the 4-zinc human insulin hexamer. Proc Natl Acad Sci U S A (1984) 1.42
Very early prediction of restenosis after successful coronary angioplasty: anatomic and functional assessment. J Am Coll Cardiol (1990) 1.41
The complex of DNA gyrase and quinolone drugs with DNA forms a barrier to transcription by RNA polymerase. J Mol Biol (1994) 1.40
A comparison of adhesives useable in the cold for the preparation of cryostat sections. Stain Technol (1971) 1.39
DNA supercoiling by DNA gyrase. A static head analysis. Cell Biophys (1988) 1.37
The crystal structure of the catalytic core domain of endoglucanase I from Trichoderma reesei at 3.6 A resolution, and a comparison with related enzymes. J Mol Biol (1997) 1.37
Does NMR mean "not for molecular replacement"? Using NMR-based search models to solve protein crystal structures. Structure (2000) 1.36
The crystal structure of the globular domain of sheep prion protein. J Mol Biol (2004) 1.36
Probing the limits of the DNA breakage-reunion domain of the Escherichia coli DNA gyrase A protein. J Biol Chem (1991) 1.36
X-ray analysis of the single chain B29-A1 peptide-linked insulin molecule. A completely inactive analogue. J Mol Biol (1991) 1.36
Neutron and light-scattering studies of DNA gyrase and its complex with DNA. J Mol Biol (1990) 1.35
Penicillin V acylase crystal structure reveals new Ntn-hydrolase family members. Nat Struct Biol (1999) 1.35
The structure of the saccharide-binding site of concanavalin A. EMBO J (1989) 1.34
Zinc-free cubic pig insulin: crystallization and structure determination. J Mol Biol (1978) 1.34
Regulatory features of the trp operon and the crystal structure of the trp RNA-binding attenuation protein from Bacillus stearothermophilus. J Mol Biol (1999) 1.32
Endothelin is a potent long-lasting vasoconstrictor in men. Am J Physiol (1989) 1.32
Probing the binding of coumarins and cyclothialidines to DNA gyrase. Biochemistry (1999) 1.32
DNA cleavage is not required for the binding of quinolone drugs to the DNA gyrase-DNA complex. Biochemistry (1996) 1.31
Patellofemoral disorders: a classification system and clinical guidelines for nonoperative rehabilitation. J Orthop Sports Phys Ther (1998) 1.31
Major circadian fluctuations in fibrinolytic factors and possible relevance to time of onset of myocardial infarction, sudden cardiac death and stroke. Am J Cardiol (1988) 1.31
Prevention of myocardial infarction by very early treatment with intracoronary streptokinase. Some clinical observations. N Engl J Med (1984) 1.28
Psychosocial interest, medical interviews, and the recognition of depression. Arch Fam Med (1994) 1.28
The crystal structures of the oligopeptide-binding protein OppA complexed with tripeptide and tetrapeptide ligands. Structure (1995) 1.28
The x-ray crystal structure of phosphomannose isomerase from Candida albicans at 1.7 angstrom resolution. Nat Struct Biol (1996) 1.27
Evidence for a conformational change in the DNA gyrase-DNA complex from hydroxyl radical footprinting. Nucleic Acids Res (1994) 1.27
The interaction of coumarin antibiotics with fragments of DNA gyrase B protein. Biochemistry (1996) 1.27