Dendritic cells rapidly recruited into epithelial tissues via CCR6/CCL20 are responsible for CD8+ T cell crosspriming in vivo.

PubWeight™: 2.62‹?› | Rank: Top 1%

🔗 View Article (PMID 16473831)

Published in Immunity on February 01, 2006

Authors

Marie Le Borgne1, Nathalie Etchart, Anne Goubier, Sergio A Lira, Jean Claude Sirard, Nico van Rooijen, Christophe Caux, Smina Aït-Yahia, Alain Vicari, Dominique Kaiserlian, Bertrand Dubois

Author Affiliations

1: INSERM U404 "Immunité et Vaccination", IFR128 BioSciences Lyon-Gerland, F-69365 Lyon, France.

Articles citing this

Monocyte recruitment during infection and inflammation. Nat Rev Immunol (2011) 7.55

Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model. J Exp Med (2007) 5.58

Phagocyte partnership during the onset and resolution of inflammation. Nat Rev Immunol (2010) 4.07

Gr1(+) inflammatory monocytes are required for mucosal resistance to the pathogen Toxoplasma gondii. Immunity (2008) 4.07

Cross-presentation by dendritic cells. Nat Rev Immunol (2012) 3.95

Respiratory dendritic cell subsets differ in their capacity to support the induction of virus-specific cytotoxic CD8+ T cell responses. PLoS One (2009) 2.70

Plasmacytoid dendritic cells mediate oral tolerance. Immunity (2008) 2.66

Protective influenza-specific CD8 T cell responses require interactions with dendritic cells in the lungs. J Exp Med (2008) 2.55

Langerhans cells are not required for efficient skin graft rejection. J Invest Dermatol (2008) 2.41

Temporal changes in dendritic cell subsets, cross-priming and costimulation via CD70 control CD8(+) T cell responses to influenza. Nat Immunol (2010) 2.27

International Union of Basic and Clinical Pharmacology. [corrected]. LXXXIX. Update on the extended family of chemokine receptors and introducing a new nomenclature for atypical chemokine receptors. Pharmacol Rev (2013) 2.11

Recruitment of beneficial M2 macrophages to injured spinal cord is orchestrated by remote brain choroid plexus. Immunity (2013) 2.08

Th17 cytokines stimulate CCL20 expression in keratinocytes in vitro and in vivo: implications for psoriasis pathogenesis. J Invest Dermatol (2009) 1.94

Luminal bacteria recruit CD103+ dendritic cells into the intestinal epithelium to sample bacterial antigens for presentation. Immunity (2013) 1.89

Antigen presentation by monocytes and monocyte-derived cells. Curr Opin Immunol (2007) 1.74

Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC. Nat Genet (2010) 1.69

CCR6 is required for IL-23-induced psoriasis-like inflammation in mice. J Clin Invest (2009) 1.65

Keratinocytes function as accessory cells for presentation of endogenous antigen expressed in the epidermis. J Invest Dermatol (2009) 1.59

Early immune events in the induction of allergic contact dermatitis. Nat Rev Immunol (2012) 1.54

Different cross-presentation pathways in steady-state and inflammatory dendritic cells. Proc Natl Acad Sci U S A (2009) 1.46

Neonatal Fc receptor for IgG (FcRn) regulates cross-presentation of IgG immune complexes by CD8-CD11b+ dendritic cells. Proc Natl Acad Sci U S A (2011) 1.44

JAM-C regulates unidirectional monocyte transendothelial migration in inflammation. Blood (2007) 1.38

Human keratinocytes' response to injury upregulates CCL20 and other genes linking innate and adaptive immunity. J Invest Dermatol (2011) 1.30

Unique type I interferon responses determine the functional fate of migratory lung dendritic cells during influenza virus infection. PLoS Pathog (2011) 1.28

MHC class I/peptide transfer between dendritic cells overcomes poor cross-presentation by monocyte-derived APCs that engulf dying cells. J Immunol (2009) 1.21

Candida albicans yeast and hyphae are discriminated by MAPK signaling in vaginal epithelial cells. PLoS One (2011) 1.15

Therapeutic HPV DNA vaccines. Immunol Res (2010) 1.12

Development, regulation and functional capacities of Th17 cells. Semin Immunopathol (2010) 1.10

Langerhans cells protect from allergic contact dermatitis in mice by tolerizing CD8(+) T cells and activating Foxp3(+) regulatory T cells. J Clin Invest (2012) 1.09

Cholera toxin, E. coli heat-labile toxin, and non-toxic derivatives induce dendritic cell migration into the follicle-associated epithelium of Peyer's patches. Mucosal Immunol (2008) 1.08

Plasticity of Ly-6C(hi) myeloid cells in T cell regulation. J Immunol (2011) 1.07

Type I IFN receptor regulates neutrophil functions and innate immunity to Leishmania parasites. J Immunol (2010) 1.06

Ly6C(low) monocytes differentiate into dendritic cells and cross-tolerize T cells through PDL-1. J Immunol (2009) 1.06

CCR6-dependent recruitment of blood phagocytes is necessary for rapid CD4 T cell responses to local bacterial infection. Proc Natl Acad Sci U S A (2007) 1.01

Functional role of intrahepatic monocyte subsets for the progression of liver inflammation and liver fibrosis in vivo. Fibrogenesis Tissue Repair (2012) 1.00

Genetic deletion of chemokine receptor Ccr6 decreases atherogenesis in ApoE-deficient mice. Circ Res (2011) 0.96

Monocyte recruitment to the dermis and differentiation to dendritic cells increases the targets for dengue virus replication. PLoS Pathog (2014) 0.96

Human papillomavirus type 8 interferes with a novel C/EBPβ-mediated mechanism of keratinocyte CCL20 chemokine expression and Langerhans cell migration. PLoS Pathog (2012) 0.96

Dendritic cells of the oral mucosa. Mucosal Immunol (2013) 0.96

CARMA3 mediates lysophosphatidic acid-stimulated cytokine secretion by bronchial epithelial cells. Am J Respir Cell Mol Biol (2008) 0.96

Kinin danger signals proteolytically released by gingipain induce Fimbriae-specific IFN-gamma- and IL-17-producing T cells in mice infected intramucosally with Porphyromonas gingivalis. J Immunol (2009) 0.94

Tyrosine phosphatase SHP-1 in oxidative stress and development of allergic airway inflammation. Am J Respir Cell Mol Biol (2008) 0.94

Heterogeneity of respiratory dendritic cell subsets and lymphocyte populations in inbred mouse strains. Respir Res (2012) 0.93

Isolated lymphoid follicles in colon: switch points between inflammation and colorectal cancer? World J Gastroenterol (2011) 0.92

CCR6 ligands inhibit HIV by inducing APOBEC3G. Blood (2009) 0.92

TLR8 agonists stimulate newly recruited monocyte-derived cells into potent APCs that enhance HBsAg immunogenicity. Vaccine (2010) 0.91

The biology of chemokines and their receptors. Immunol Res (2012) 0.91

Preferential amplification of CD8 effector-T cells after transcutaneous application of an inactivated influenza vaccine: a randomized phase I trial. PLoS One (2010) 0.91

Current evidence on intradermal influenza vaccines administered by Soluvia™ licensed micro injection system. Hum Vaccin Immunother (2012) 0.90

Therapeutic HPV DNA vaccines. Expert Rev Vaccines (2009) 0.90

Oral probiotic control skin inflammation by acting on both effector and regulatory T cells. PLoS One (2009) 0.89

Antigen-bearing dendritic cells from the sublingual mucosa recirculate to distant systemic lymphoid organs to prime mucosal CD8 T cells. Mucosal Immunol (2013) 0.89

CCR6 as a possible therapeutic target in psoriasis. Expert Opin Ther Targets (2010) 0.88

Modulation of respiratory dendritic cells during Klebsiella pneumonia infection. Respir Res (2013) 0.88

Why functional pre-erythrocytic and bloodstage malaria vaccines fail: a meta-analysis of fully protective immunizations and novel immunological model. PLoS One (2010) 0.87

Airway structural cells regulate TLR5-mediated mucosal adjuvant activity. Mucosal Immunol (2013) 0.87

Hepatitis B vaccine by intradermal route in non responder patients: an update. World J Gastroenterol (2014) 0.86

Identification of avian RIG-I responsive genes during influenza infection. Mol Immunol (2012) 0.86

CCR6/CCR10-mediated plasmacytoid dendritic cell recruitment to inflamed epithelia after instruction in lymphoid tissues. Blood (2011) 0.86

The chemokine system in innate immunity. Cold Spring Harb Perspect Biol (2015) 0.85

Lupus serum IgG induces skin inflammation through the TNFR1 signaling pathway. J Immunol (2010) 0.84

Cysteine-cysteinyl chemokine receptor 6 mediates invariant natural killer T cell airway recruitment and innate stage resistance during mycobacterial infection. J Innate Immun (2010) 0.84

Interplay between CD8α+ dendritic cells and monocytes in response to Listeria monocytogenes infection attenuates T cell responses. PLoS One (2011) 0.84

The lung vascular filter as a site of immune induction for T cell responses to large embolic antigen. J Exp Med (2009) 0.83

Cross-Presentation of Cell-Associated Antigens by MHC Class I in Dendritic Cell Subsets. Front Immunol (2015) 0.83

Role of Inflammatory Monocytes in Vaccine-Induced Reduction of Helicobacter felis Infection. Infect Immun (2015) 0.82

Therapeutic effectiveness of intratumorally delivered dendritic cells engineered to express the pro-inflammatory cytokine, interleukin (IL)-32. Cancer Gene Ther (2011) 0.82

Origin, Localization, and Immunoregulatory Properties of Pulmonary Phagocytes in Allergic Asthma. Front Immunol (2016) 0.82

Laser vaccine adjuvants. History, progress, and potential. Hum Vaccin Immunother (2014) 0.82

Pulmonary expression of oncostatin M (OSM) promotes inducible BALT formation independently of IL-6, despite a role for IL-6 in OSM-driven pulmonary inflammation. J Immunol (2013) 0.82

A novel population of human CD56+ human leucocyte antigen D-related (HLA-DR+) colonic lamina propria cells is associated with inflammation in ulcerative colitis. Clin Exp Immunol (2009) 0.81

Enhancing DNA vaccine potency by co-administration of xenogenic MHC class-I DNA. Gene Ther (2009) 0.80

Induction of RET dependent and independent pro-inflammatory programs in human peripheral blood mononuclear cells from Hirschsprung patients. PLoS One (2013) 0.79

Effects of flagellin on the functions of follicle-associated epithelium. J Infect Dis (2008) 0.79

The serine protease plasmin triggers expression of the CC-chemokine ligand 20 in dendritic cells via Akt/NF-κB-dependent pathways. J Biomed Biotechnol (2012) 0.79

Aryl Hydrocarbon Receptor Activation Synergistically Induces Lipopolysaccharide-Mediated Expression of Proinflammatory Chemokine (c-c motif) Ligand 20. Toxicol Sci (2015) 0.79

Role of G protein-coupled receptors in control of dendritic cell migration. Biomed Res Int (2014) 0.79

Effect of human papillomavirus infection on the immune system and its role in the course of cervical cancer. Oncol Lett (2015) 0.79

Dendritic cells as immune regulators: the mouse model. J Cell Mol Med (2008) 0.78

Towards a cure for food allergy. Curr Opin Immunol (2008) 0.78

Genetic Susceptibility to Vitiligo: GWAS Approaches for Identifying Vitiligo Susceptibility Genes and Loci. Front Genet (2016) 0.78

Regulation of atherogenesis by chemokine receptor CCR6. Trends Cardiovasc Med (2011) 0.77

Potential roles of CCR5(+) CCR6(+) dendritic cells induced by nasal ovalbumin plus Flt3 ligand expressing adenovirus for mucosal IgA responses. PLoS One (2013) 0.77

Targeting the GM-CSF receptor for the treatment of CNS autoimmunity. J Autoimmun (2017) 0.76

RIG-I Signaling Is Critical for Efficient Polyfunctional T Cell Responses during Influenza Virus Infection. PLoS Pathog (2016) 0.76

Depletion of tumor-associated macrophages enhances the anti-tumor immunity induced by a Toll-like receptor agonist-conjugated peptide. Hum Vaccin Immunother (2014) 0.76

Effect of Mucosal Cytokine Administration on Selective Expansion of Vaginal Dendritic Cells to Support Nanoparticle Transport. Am J Reprod Immunol (2015) 0.76

Heterogeneity, functional specialization and differentiation of monocyte-derived dendritic cells. Immunol Cell Biol (2016) 0.76

Transgenic mouse model harboring the transcriptional fusion ccl20-luciferase as a novel reporter of pro-inflammatory response. PLoS One (2013) 0.75

Monocyte-derived inflammatory Langerhans cells and dermal dendritic cells mediate psoriasis-like inflammation. Nat Commun (2016) 0.75

Self-adjuvanting C18 lipid vinil sulfone-PP2A vaccine: study of the induced immunomodulation against Trichuris muris infection. Open Biol (2017) 0.75

Monocyte-Derived Dendritic Cells Are Essential for CD8(+) T Cell Activation and Antitumor Responses After Local Immunotherapy. Front Immunol (2015) 0.75

Identification of the Single Immunodominant Region of the Native Human CC Chemokine Receptor 6 Recognized by Mouse Monoclonal Antibodies. PLoS One (2016) 0.75

Analyzed immunogenicity of fractional doses of Sabin-inactivated poliovirus vaccine (sIPV) with intradermal delivery in rats. Hum Vaccin Immunother (2016) 0.75

CCR6 Promotes Steady State Intestinal Mononuclear Phagocyte Association with the Intestinal Epithelium, Imprinting, and Immune Surveillance. Immunology (2017) 0.75

Articles by these authors

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature (2003) 22.89

Mesenchymal and haematopoietic stem cells form a unique bone marrow niche. Nature (2010) 15.28

Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques. J Clin Invest (2007) 9.09

Local macrophage proliferation, rather than recruitment from the blood, is a signature of TH2 inflammation. Science (2011) 8.53

Control of microglial neurotoxicity by the fractalkine receptor. Nat Neurosci (2006) 8.25

Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis. J Exp Med (2007) 7.87

Dynamics and function of Langerhans cells in vivo: dermal dendritic cells colonize lymph node areas distinct from slower migrating Langerhans cells. Immunity (2005) 6.48

Origin of the lamina propria dendritic cell network. Immunity (2009) 5.95

Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes. Immunity (2013) 5.47

Cross-priming of CD8+ T cells stimulated by virus-induced type I interferon. Nat Immunol (2003) 5.36

CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells. Cell (2009) 5.30

CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis. Cell (2009) 5.22

Anti-PlGF inhibits growth of VEGF(R)-inhibitor-resistant tumors without affecting healthy vessels. Cell (2007) 5.09

Adenovirus serotype 5 hexon mediates liver gene transfer. Cell (2008) 5.00

Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts. Nat Immunol (2006) 5.00

Subcapsular sinus macrophages in lymph nodes clear lymph-borne viruses and present them to antiviral B cells. Nature (2007) 4.88

The origin and development of nonlymphoid tissue CD103+ DCs. J Exp Med (2009) 4.79

MHC class II-dependent basophil-CD4+ T cell interactions promote T(H)2 cytokine-dependent immunity. Nat Immunol (2009) 4.28

Local proliferation dominates lesional macrophage accumulation in atherosclerosis. Nat Med (2013) 4.14

Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C-dependent buffering mechanism. Nat Med (2009) 4.07

Dendritic cell-induced memory T cell activation in nonlymphoid tissues. Science (2008) 3.97

Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche. J Exp Med (2011) 3.88

A type I interferon autocrine-paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells. J Exp Med (2005) 3.59

Immature monocytes acquire antigens from other cells in the bone marrow and present them to T cells after maturing in the periphery. J Exp Med (2006) 3.43

Microglia promote the death of developing Purkinje cells. Neuron (2004) 3.42

IL-33 amplifies the polarization of alternatively activated macrophages that contribute to airway inflammation. J Immunol (2009) 3.41

Regulatory T cells recruited through CCL22/CCR4 are selectively activated in lymphoid infiltrates surrounding primary breast tumors and lead to an adverse clinical outcome. Cancer Res (2009) 3.31

Alveolar macrophages have a protective antiinflammatory role during murine pneumococcal pneumonia. Am J Respir Crit Care Med (2002) 3.27

Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs. Blood (2010) 3.26

Depletion of host Langerhans cells before transplantation of donor alloreactive T cells prevents skin graft-versus-host disease. Nat Med (2004) 3.17

Macrophage depletion inhibits experimental choroidal neovascularization. Invest Ophthalmol Vis Sci (2003) 3.17

The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity. Cell Metab (2010) 3.11

Toll-like receptor-4 signaling and Kupffer cells play pivotal roles in the pathogenesis of non-alcoholic steatohepatitis. J Hepatol (2007) 3.06

Blood monocyte subsets differentially give rise to CD103+ and CD103- pulmonary dendritic cell populations. J Immunol (2008) 3.04

The chemokine receptor D6 limits the inflammatory response in vivo. Nat Immunol (2005) 2.98

Macrophage depletion impairs wound healing and increases left ventricular remodeling after myocardial injury in mice. Am J Pathol (2007) 2.84

Hypoxia-induced pulmonary vascular remodeling requires recruitment of circulating mesenchymal precursors of a monocyte/macrophage lineage. Am J Pathol (2006) 2.70

Role of CCR8 and other chemokine pathways in the migration of monocyte-derived dendritic cells to lymph nodes. J Exp Med (2004) 2.68

Plasmacytoid dendritic cells mediate oral tolerance. Immunity (2008) 2.66

Minimal differentiation of classical monocytes as they survey steady-state tissues and transport antigen to lymph nodes. Immunity (2013) 2.61

Excessive neutrophils and neutrophil extracellular traps contribute to acute lung injury of influenza pneumonitis. Am J Pathol (2011) 2.57

Identification of coagulation factor (F)X binding sites on the adenovirus serotype 5 hexon: effect of mutagenesis on FX interactions and gene transfer. Blood (2009) 2.55

Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosis. Proc Natl Acad Sci U S A (2012) 2.54

Type I interferon dependence of plasmacytoid dendritic cell activation and migration. J Exp Med (2005) 2.53

Kupffer cells promote hepatic steatosis via interleukin-1beta-dependent suppression of peroxisome proliferator-activated receptor alpha activity. Hepatology (2010) 2.53

CX3CR1 is required for monocyte homeostasis and atherogenesis by promoting cell survival. Blood (2008) 2.52

Strategies for use of IL-10 or its antagonists in human disease. Immunol Rev (2008) 2.52

Enforced viral replication activates adaptive immunity and is essential for the control of a cytopathic virus. Nat Immunol (2011) 2.51

Dystroglycan is selectively cleaved at the parenchymal basement membrane at sites of leukocyte extravasation in experimental autoimmune encephalomyelitis. J Exp Med (2006) 2.51

Kupffer cell and interleukin-12-dependent loss of natural killer T cells in hepatosteatosis. Hepatology (2010) 2.48

Chemokines in cancer. Cytokine Growth Factor Rev (2002) 2.47

Extramedullary hematopoiesis generates Ly-6C(high) monocytes that infiltrate atherosclerotic lesions. Circulation (2011) 2.45

Rapid induction of inflammatory lipid mediators by the inflammasome in vivo. Nature (2012) 2.41

Stress-induced production of chemokines by hair follicles regulates the trafficking of dendritic cells in skin. Nat Immunol (2012) 2.40

On the pathogenic role of brain-sequestered alphabeta CD8+ T cells in experimental cerebral malaria. J Immunol (2002) 2.40

Suppressed monocyte recruitment drives macrophage removal from atherosclerotic plaques of Apoe-/- mice during disease regression. J Clin Invest (2011) 2.37

CCR2 promotes hepatic fibrosis in mice. Hepatology (2009) 2.35

Role of macrophage targeting in the antitumor activity of trabectedin. Cancer Cell (2013) 2.35

Tollip regulates proinflammatory responses to interleukin-1 and lipopolysaccharide. Mol Cell Biol (2006) 2.33

Simultaneous targeting of toll- and nod-like receptors induces effective tumor-specific immune responses. Sci Transl Med (2012) 2.33

CD169⁺ macrophages provide a niche promoting erythropoiesis under homeostasis and stress. Nat Med (2013) 2.26

Reversal of tumor-induced dendritic cell paralysis by CpG immunostimulatory oligonucleotide and anti-interleukin 10 receptor antibody. J Exp Med (2002) 2.25

Dual roles for perivascular macrophages in immune-to-brain signaling. Neuron (2010) 2.24

Another barrier to regeneration in the CNS: activated macrophages induce extensive retraction of dystrophic axons through direct physical interactions. J Neurosci (2008) 2.20

Rhythmic modulation of the hematopoietic niche through neutrophil clearance. Cell (2013) 2.19

The role of complement in the therapeutic activity of rituximab in a murine B lymphoma model homing in lymph nodes. Haematologica (2006) 2.19

Modulation of dendritic cell trafficking to and from the airways. J Immunol (2006) 2.17

Resolution-phase macrophages possess a unique inflammatory phenotype that is controlled by cAMP. Blood (2008) 2.16

Ly6Chi monocytes direct alternatively activated profibrotic macrophage regulation of lung fibrosis. Am J Respir Crit Care Med (2011) 2.15

The sphingosine 1-phosphate receptor 1 causes tissue retention by inhibiting the entry of peripheral tissue T lymphocytes into afferent lymphatics. Nat Immunol (2007) 2.13

Flagellin promotes myeloid differentiation factor 88-dependent development of Th2-type response. J Immunol (2004) 2.13

Infection with a helminth parasite prevents experimental colitis via a macrophage-mediated mechanism. J Immunol (2007) 2.09

Th2 cytokine-induced alterations in intestinal smooth muscle function depend on alternatively activated macrophages. Gastroenterology (2008) 2.09

Recruitment of beneficial M2 macrophages to injured spinal cord is orchestrated by remote brain choroid plexus. Immunity (2013) 2.08

CX3CR1 regulates intestinal macrophage homeostasis, bacterial translocation, and colitogenic Th17 responses in mice. J Clin Invest (2011) 2.08

Fractalkine deficiency markedly reduces macrophage accumulation and atherosclerotic lesion formation in CCR2-/- mice: evidence for independent chemokine functions in atherogenesis. Circulation (2007) 2.06

Age-dependent hepatic lymphoid organization directs successful immunity to hepatitis B. J Clin Invest (2013) 2.04

Flow-dependent remodeling of small arteries in mice deficient for tissue-type transglutaminase: possible compensation by macrophage-derived factor XIII. Circ Res (2006) 2.03

An intravascular immune response to Borrelia burgdorferi involves Kupffer cells and iNKT cells. Nat Immunol (2010) 2.03

Recognition of double-stranded RNA by human toll-like receptor 3 and downstream receptor signaling requires multimerization and an acidic pH. J Biol Chem (2005) 2.03

Mononuclear phagocyte system depletion blocks interstitial tonicity-responsive enhancer binding protein/vascular endothelial growth factor C expression and induces salt-sensitive hypertension in rats. Hypertension (2010) 2.01

TLR7-dependent and FcgammaR-independent production of type I interferon in experimental mouse lupus. J Exp Med (2008) 1.99

MyD88-dependent and -independent murine cytomegalovirus sensing for IFN-alpha release and initiation of immune responses in vivo. J Immunol (2005) 1.92

Suppression of experimental colitis by intestinal mononuclear phagocytes. J Leukoc Biol (2006) 1.90

Toll-like receptor signaling in small intestinal epithelium promotes B-cell recruitment and IgA production in lamina propria. Gastroenterology (2008) 1.89

Luminal bacteria recruit CD103+ dendritic cells into the intestinal epithelium to sample bacterial antigens for presentation. Immunity (2013) 1.89

Hepatocyte entry leads to degradation of autoreactive CD8 T cells. Proc Natl Acad Sci U S A (2011) 1.89

Vascular endothelial growth factor-induced skin carcinogenesis depends on recruitment and alternative activation of macrophages. J Pathol (2012) 1.87

Hepatic recruitment of macrophages promotes nonalcoholic steatohepatitis through CCR2. Am J Physiol Gastrointest Liver Physiol (2012) 1.87

Human FcγRIIA induces anaphylactic and allergic reactions. Blood (2011) 1.86

Kupffer cell activation is a causal factor for hepatic insulin resistance. Am J Physiol Gastrointest Liver Physiol (2009) 1.85

Critical roles of macrophages in the formation of intracranial aneurysm. Stroke (2010) 1.85

An antigen-specific pathway for CD8 T cells across the blood-brain barrier. J Exp Med (2007) 1.84

Macrophages prevent hemorrhagic infarct transformation in murine stroke models. Ann Neurol (2012) 1.84

Transient lung-specific expression of the chemokine KC improves outcome in invasive aspergillosis. Am J Respir Crit Care Med (2002) 1.82