Published in Eur Urol on January 06, 2006
Studies on anticancer activities of antimicrobial peptides. Biochim Biophys Acta (2007) 3.24
FK-16 derived from the anticancer peptide LL-37 induces caspase-independent apoptosis and autophagic cell death in colon cancer cells. PLoS One (2013) 1.65
Membrane-active host defense peptides--challenges and perspectives for the development of novel anticancer drugs. Chem Phys Lipids (2011) 1.45
The use of therapeutic peptides to target and to kill cancer cells. Curr Med Chem (2012) 1.04
Magainin 2 in action: distinct modes of membrane permeabilization in living bacterial and mammalian cells. Biophys J (2008) 1.00
Oncolytic activities of host defense peptides. Int J Mol Sci (2011) 1.00
Antimicrobial peptaibols, novel suppressors of tumor cells, targeted calcium-mediated apoptosis and autophagy in human hepatocellular carcinoma cells. Mol Cancer (2010) 0.99
Current scenario of peptide-based drugs: the key roles of cationic antitumor and antiviral peptides. Front Microbiol (2013) 0.98
Antimicrobial peptides of the Cecropin-family show potent antitumor activity against bladder cancer cells. BMC Urol (2008) 0.98
On the physiology and pathophysiology of antimicrobial peptides. Mol Med (2008) 0.93
Novel formulations for antimicrobial peptides. Int J Mol Sci (2014) 0.91
Host-defense peptides with therapeutic potential from skin secretions of frogs from the family pipidae. Pharmaceuticals (Basel) (2014) 0.88
Enhancement of cytotoxicity of antimicrobial peptide magainin II in tumor cells by bombesin-targeted delivery. Acta Pharmacol Sin (2010) 0.86
Identification of a novel lytic peptide for the treatment of solid tumours. Genes Cancer (2014) 0.85
The zebrafish embryo as a tool for screening and characterizing pleurocidin host-defense peptides as anti-cancer agents. Dis Model Mech (2011) 0.83
Deciphering the magainin resistance process of Escherichia coli strains in light of the cytosolic proteome. Antimicrob Agents Chemother (2012) 0.82
Suppression of soft tissue sarcoma growth by a host defense-like lytic peptide. PLoS One (2011) 0.82
Antiproliferative effect and characterization of a novel antifungal peptide derived from human Chromogranin A. Exp Ther Med (2015) 0.81
PFR peptide, one of the antimicrobial peptides identified from the derivatives of lactoferrin, induces necrosis in leukemia cells. Sci Rep (2016) 0.80
Current and potential applications of host-defense peptides and proteins in urology. Biomed Res Int (2015) 0.80
17Beta-estradiol affects the proliferation and apoptosis of rat bladder neck smooth muscle cells by modulating cell cycle transition and related proteins. World J Urol (2008) 0.78
Evaluation of the use of therapeutic peptides for cancer treatment. J Biomed Sci (2017) 0.75
Targeting and eradicating hepatic cancer cells with a cancer-specific vector carrying the Buforin II gene. Cancer Biother Radiopharm (2013) 0.75
The cytotoxic effect of magainin II on the MDA-MB-231 and M14K tumour cell lines. Biomed Res Int (2013) 0.75
Anti-proliferative effect on a colon adenocarcinoma cell line exerted by a membrane disrupting antimicrobial peptide KL15. Cancer Biol Ther (2015) 0.75
Morin Inhibits Proliferation of SW480 Colorectal Cancer Cells by Inducing Apoptosis Mediated by Reactive Oxygen Species Formation and Uncoupling of Warburg Effect. Front Pharmacol (2017) 0.75
Isoflurane decreases proliferation and differentiation, but none of the effects persist in human embryonic stem cell-derived neural progenitor cells. J Anesth (2016) 0.75
Abiraterone in metastatic prostate cancer without previous chemotherapy. N Engl J Med (2012) 15.69
Phase III postoperative adjuvant radiotherapy after radical prostatectomy compared with radical prostatectomy alone in pT3 prostate cancer with postoperative undetectable prostate-specific antigen: ARO 96-02/AUO AP 09/95. J Clin Oncol (2009) 5.62
Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids. Proc Natl Acad Sci U S A (2007) 4.21
Antimicrobial psoriasin (S100A7) protects human skin from Escherichia coli infection. Nat Immunol (2004) 3.19
Assessing the impact of ischaemia time during partial nephrectomy. Eur Urol (2009) 3.18
A 20-gene model for molecular nodal staging of bladder cancer: development and prospective assessment. Lancet Oncol (2011) 2.89
NF-kappaB- and AP-1-mediated induction of human beta defensin-2 in intestinal epithelial cells by Escherichia coli Nissle 1917: a novel effect of a probiotic bacterium. Infect Immun (2004) 2.47
Cutting edge: critical role for mesothelial cells in necrosis-induced inflammation through the recognition of IL-1 alpha released from dying cells. J Immunol (2008) 2.13
Excellent long-term cancer control with elective nephron-sparing surgery for selected renal cell carcinomas measuring more than 4 cm. Eur Urol (2006) 2.11
NOD2/CARD15 mediates induction of the antimicrobial peptide human beta-defensin-2. J Biol Chem (2005) 2.06
Important aspects of organ-preserving surgery for renal tumors: indications, new standards, and oncological outcomes. Dtsch Arztebl Int (2009) 2.05
Surgery for metastatic urothelial carcinoma with curative intent: the German experience (AUO AB 30/05). Eur Urol (2008) 2.02
Guidelines on bladder cancer. Eur Urol (2002) 1.97
Adjuvant cisplatin plus methotrexate versus methotrexate, vinblastine, epirubicin, and cisplatin in locally advanced bladder cancer: results of a randomized, multicenter, phase III trial (AUO-AB 05/95). J Clin Oncol (2005) 1.93
Transitional cell carcinoma of the ureter: prognostic factors influencing progression and survival. Eur Urol (2006) 1.86
Complete long-term survival data from a trial of adjuvant chemotherapy vs control after radical cystectomy for locally advanced bladder cancer. BJU Int (2006) 1.85
The microRNA profile of prostate carcinoma obtained by deep sequencing. Mol Cancer Res (2010) 1.75
Cytosolic DNA triggers inflammasome activation in keratinocytes in psoriatic lesions. Sci Transl Med (2011) 1.74
Myeloid-derived suppressor cells in the peripheral blood of cancer patients contain a subset of immature neutrophils with impaired migratory properties. J Leukoc Biol (2010) 1.71
Degradation by stratum corneum proteases prevents endogenous RNase inhibitor from blocking antimicrobial activities of RNase 5 and RNase 7. J Invest Dermatol (2009) 1.70
RNase 7 protects healthy skin from Staphylococcus aureus colonization. J Invest Dermatol (2010) 1.69
Epidermal EGFR controls cutaneous host defense and prevents inflammation. Sci Transl Med (2013) 1.69
Cabazitaxel plus prednisone for metastatic castration-resistant prostate cancer progressing after docetaxel: results from the German compassionate-use programme. Eur Urol (2012) 1.69
Accumulation of intraepithelial mast cells with a unique protease phenotype in T(H)2-high asthma. J Allergy Clin Immunol (2010) 1.63
Short-term functional and oncologic outcomes of nephron-sparing surgery for renal tumours ≥ 7 cm. Eur Urol (2011) 1.63
Ptf1a is essential for the differentiation of GABAergic and glycinergic amacrine cells and horizontal cells in the mouse retina. Development (2007) 1.57
Uncovering the evolutionary history of innate immunity: the simple metazoan Hydra uses epithelial cells for host defence. Dev Comp Immunol (2008) 1.55
Production of endogenous antibiotics in articular cartilage. Arthritis Rheum (2004) 1.55
Neutrophil granulocytes are required for effective Bacillus Calmette-Guérin immunotherapy of bladder cancer and orchestrate local immune responses. Cancer Res (2006) 1.52
Outcome of prostate cancer patients with initial PSA> or =20 ng/ml undergoing radical prostatectomy. Eur Urol (2007) 1.49
Phylogenetic analysis of the vertebrate galectin family. Mol Biol Evol (2004) 1.46
The international workshop on meibomian gland dysfunction: report of the subcommittee on tear film lipids and lipid-protein interactions in health and disease. Invest Ophthalmol Vis Sci (2011) 1.46
Detection of occult tumor cells in lymph nodes from bladder cancer patients by MUC7 nested RT-PCR. Eur Urol (2004) 1.44
Prenatal diagnosis of congenital mesoblastic nephroma associated with renal hypertension in a premature child. Int J Urol (2004) 1.39
Long-term follow-up of bladder cancer patients with disseminated tumour cells in bone marrow. Eur Urol (2010) 1.39
MDR1 and ERCC1 expression predict outcome of patients with locally advanced bladder cancer receiving adjuvant chemotherapy. Neoplasia (2010) 1.37
Wnt and Hedgehog are critical mediators of cigarette smoke-induced lung cancer. PLoS One (2006) 1.34
Wilms' tumor in adults: results of the Society of Pediatric Oncology (SIOP) 93-01/Society for Pediatric Oncology and Hematology (GPOH) Study. J Clin Oncol (2004) 1.33
UV-B radiation induces the expression of antimicrobial peptides in human keratinocytes in vitro and in vivo. J Allergy Clin Immunol (2009) 1.31
Burkholderia is highly resistant to human Beta-defensin 3. Antimicrob Agents Chemother (2003) 1.29
Is there a need to further subclassify pT2 renal cell cancers as implemented by the revised 7th TNM version? Eur Urol (2010) 1.26
Thirty years of BCG immunotherapy for non-muscle invasive bladder cancer: a success story with room for improvement. Biomed Pharmacother (2007) 1.25
Ribonuclease 7 is a potent antimicrobial peptide within the human urinary tract. Kidney Int (2011) 1.25
Expression of human beta-defensins 1 and 2 in kidneys with chronic bacterial infection. BMC Infect Dis (2002) 1.20
The antimicrobial protein psoriasin (S100A7) is upregulated in atopic dermatitis and after experimental skin barrier disruption. J Invest Dermatol (2008) 1.18
S6K1 and 4E-BP1 are independent regulated and control cellular growth in bladder cancer. PLoS One (2011) 1.17
Psoriasin (S100A7) is significantly up-regulated in human epithelial skin tumours. J Cancer Res Clin Oncol (2006) 1.15
Immune complex-dependent remodeling of the airway vasculature in response to a chronic bacterial infection. J Immunol (2005) 1.14
Galectin-7 in the control of epidermal homeostasis after injury. Mol Biol Cell (2008) 1.11
Histologic, immunohistochemical, and ultrastructural findings in human blast lung injury. Am J Respir Crit Care Med (2003) 1.11
Plasmacytoid variant of bladder cancer defines patients with poor prognosis if treated with cystectomy and adjuvant cisplatin-based chemotherapy. BMC Cancer (2013) 1.10
Detection of circulating tumor cells in different stages of prostate cancer. J Cancer Res Clin Oncol (2013) 1.09
The dissection course - necessary and indispensable for teaching anatomy to medical students. Ann Anat (2008) 1.08
Enzalutamide after docetaxel and abiraterone therapy in metastatic castration-resistant prostate cancer. Adv Ther (2014) 1.07
Mouse beta-defensin-14, an antimicrobial ortholog of human beta-defensin-3. Antimicrob Agents Chemother (2008) 1.07
RNase 7 contributes to the cutaneous defense against Enterococcus faecium. PLoS One (2009) 1.06
Axonal transport and sorting of herpes simplex virus components in a mature mouse visual system. J Virol (2003) 1.04
Pseudomonas aeruginosa- and IL-1beta-mediated induction of human beta-defensin-2 in keratinocytes is controlled by NF-kappaB and AP-1. J Invest Dermatol (2006) 1.03
Silencing of the SEC62 gene inhibits migratory and invasive potential of various tumor cells. Int J Cancer (2011) 1.02
Mechanical and metabolic injury to the skin barrier leads to increased expression of murine β-defensin-1, -3, and -14. J Invest Dermatol (2010) 0.99
Antimicrobial peptides of the Cecropin-family show potent antitumor activity against bladder cancer cells. BMC Urol (2008) 0.98
Incidence and long-term prognosis of papillary compared to clear cell renal cell carcinoma--a multicentre study. Eur J Cancer (2012) 0.97
In vitro comparison of four cerebral protection filters for preventing human plaque embolization during carotid interventions. J Endovasc Ther (2002) 0.97
Highly complex peptide aggregates of the S100 fused-type protein hornerin are present in human skin. J Invest Dermatol (2008) 0.95
Antimicrobial RNases in cutaneous defense. J Innate Immun (2012) 0.93
ICRAC controls the rapid androgen response in human primary prostate epithelial cells and is altered in prostate cancer. Oncotarget (2013) 0.93
Human beta-defensin 3 mediates tissue remodeling processes in articular cartilage by increasing levels of metalloproteinases and reducing levels of their endogenous inhibitors. Arthritis Rheum (2005) 0.92
The human false vocal folds -- an analysis of antimicrobial defense mechanisms. Anat Embryol (Berl) (2002) 0.92
TACE/ADAM-17 phosphorylation by PKC-epsilon mediates premalignant changes in tobacco smoke-exposed lung cells. PLoS One (2011) 0.92
Impact of surgeon and volume on extended lymphadenectomy at the time of robot-assisted radical cystectomy: results from the International Robotic Cystectomy Consortium (IRCC). BJU Int (2013) 0.91
Identification of RNase 8 as a novel human antimicrobial protein. Antimicrob Agents Chemother (2006) 0.91
Vessel wall damage caused by cerebral protection devices: ex vivo evaluation in porcine carotid arteries. Radiology (2005) 0.90
Long-term survival in bilateral renal cell carcinoma: a retrospective single-institutional analysis of 101 patients after surgical treatment. Urology (2008) 0.90
Preclinical antitumor activity of the oral platinum analog satraplatin. Cancer Chemother Pharmacol (2007) 0.90
Schirmer strip vs. capillary tube method: non-invasive methods of obtaining proteins from tear fluid. Ann Anat (2012) 0.90
C-28/I2 and T/C-28a2 chondrocytes as well as human primary articular chondrocytes express sex hormone and insulin receptors--Useful cells in study of cartilage metabolism. Ann Anat (2010) 0.90
Genomic and expression analysis of the 3q25-q26 amplification unit reveals TLOC1/SEC62 as a probable target gene in prostate cancer. Mol Cancer Res (2006) 0.89
Test anxiety among German medical students and its impact on lifestyle and substance abuse. Med Teach (2013) 0.89
Pulmonary expression of vascular endothelial growth factor in sepsis. Arch Pathol Lab Med (2003) 0.89
Structural and functional alteration of corneal epithelial barrier under inflammatory conditions. Curr Eye Res (2012) 0.88
Transrectal ultrasound guided biopsy of the prostate: random sextant versus biopsies of sono-morphologically suspicious lesions. World J Urol (2004) 0.88
Differential expression pattern of antimicrobial peptides in nasal mucosa and secretion. Rhinology (2011) 0.88
Expression and regulation of antimicrobial peptide psoriasin (S100A7) at the ocular surface and in the lacrimal apparatus. Invest Ophthalmol Vis Sci (2011) 0.87
Sec62 protein level is crucial for the ER stress tolerance of prostate cancer. Prostate (2011) 0.87
IL-17A and IFN-γ synergistically induce RNase 7 expression via STAT3 in primary keratinocytes. PLoS One (2013) 0.87
Collecting duct carcinomas represent a unique tumor entity based on genetic alterations. PLoS One (2013) 0.86