Published in Proc Natl Acad Sci U S A on February 13, 2006
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The role of inflammation in epilepsy. Nat Rev Neurol (2010) 3.89
Transgenic mice with a reduced core body temperature have an increased life span. Science (2006) 3.37
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Lenalidomide downregulates the cell survival factor, interferon regulatory factor-4, providing a potential mechanistic link for predicting response. Br J Haematol (2011) 2.00
A blood based 12-miRNA signature of Alzheimer disease patients. Genome Biol (2013) 1.99
A specific role for NR2A-containing NMDA receptors in the maintenance of parvalbumin and GAD67 immunoreactivity in cultured interneurons. J Neurosci (2006) 1.93
Impaired gene and protein expression of exocytotic soluble N-ethylmaleimide attachment protein receptor complex proteins in pancreatic islets of type 2 diabetic patients. Diabetes (2006) 1.89
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Transthyretin protects Alzheimer's mice from the behavioral and biochemical effects of Abeta toxicity. Proc Natl Acad Sci U S A (2008) 1.64
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IL-1 receptor/Toll-like receptor signaling in infection, inflammation, stress and neurodegeneration couples hyperexcitability and seizures. Brain Behav Immun (2011) 1.57
The promise of single-cell sequencing. Nat Methods (2014) 1.51
Analysis of the gene expression profile activated by the CC chemokine ligand 5/RANTES and by lipopolysaccharide in human monocytes. J Immunol (2002) 1.42
Neuropeptides: opportunities for drug discovery. Lancet Neurol (2003) 1.41
Interleukin-18 controls energy homeostasis by suppressing appetite and feed efficiency. Proc Natl Acad Sci U S A (2007) 1.40
Improved recovery and delayed cytokine induction after closed head injury in mice with central overexpression of the secreted isoform of the interleukin-1 receptor antagonist. J Neurotrauma (2002) 1.40
Stabilization of labile carbonyl addition intermediates by a synthetic receptor. Science (2007) 1.39
Helical conformation of alkanes in a hydrophobic cavitand. Science (2003) 1.34
Reaction of carboxylic acids and isonitriles in small spaces. J Am Chem Soc (2008) 1.33
Metabotropic glutamate receptor 1-induced upregulation of NMDA receptor current: mediation through the Pyk2/Src-family kinase pathway in cortical neurons. J Neurosci (2002) 1.32
Reaction of isonitriles with carboxylic acids in a cavitand: observation of elusive isoimide intermediates. J Am Chem Soc (2008) 1.29
Anticonvulsant activity of a nonpeptide galanin receptor agonist. Proc Natl Acad Sci U S A (2002) 1.29
IL-6 mediated degeneration of forebrain GABAergic interneurons and cognitive impairment in aged mice through activation of neuronal NADPH oxidase. PLoS One (2009) 1.28
Single cell transcriptomics of hypothalamic warm sensitive neurons that control core body temperature and fever response Signaling asymmetry and an extension of chemical neuroanatomy. Pharmacol Ther (2010) 1.27
Downregulation of parvalbumin at cortical GABA synapses reduces network gamma oscillatory activity. J Neurosci (2011) 1.23
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Gender differences in free radical homeostasis during aging: shorter-lived female C57BL6 mice have increased oxidative stress. Aging Cell (2006) 1.22
Galmic, a nonpeptide galanin receptor agonist, affects behaviors in seizure, pain, and forced-swim tests. Proc Natl Acad Sci U S A (2004) 1.22
Brain mitochondrial uncoupling protein 2 (UCP2): a protective stress signal in neuronal injury. Biochem Pharmacol (2002) 1.21
Analyzing the validity of GalR1 and GalR2 antibodies using knockout mice. Naunyn Schmiedebergs Arch Pharmacol (2009) 1.20
Behavioral and neurochemical consequences of cortical oxidative stress on parvalbumin-interneuron maturation in rodent models of schizophrenia. Neuropharmacology (2011) 1.19
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Ceramide mediates the rapid phase of febrile response to IL-1beta. Proc Natl Acad Sci U S A (2006) 1.16
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Kinetically stable complexes in water: the role of hydration and hydrophobicity. J Am Chem Soc (2004) 1.14
Galanin and its receptors in neurological disorders. Neuromolecular Med (2005) 1.14
Detection of reactive tetrahedral intermediates in a deep cavitand with an introverted functionality. J Am Chem Soc (2007) 1.13
Functional cavitands: chemical reactivity in structured environments. Proc Natl Acad Sci U S A (2005) 1.13
Self-assembled capsules of unprecedented shapes. Angew Chem Int Ed Engl (2011) 1.13
Prolonged exposure to NMDAR antagonist suppresses inhibitory synaptic transmission in prefrontal cortex. J Neurophysiol (2008) 1.13
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Galanin type 2 receptors regulate neuronal survival, susceptibility to seizures and seizure-induced neurogenesis in the dentate gyrus. Eur J Neurosci (2004) 1.10
Organocatalysis in a synthetic receptor with an inwardly directed carboxylic acid. J Am Chem Soc (2008) 1.08
The neuropeptide galanin modulates behavioral and neurochemical signs of opiate withdrawal. Proc Natl Acad Sci U S A (2003) 1.07
Measuring cereblon as a biomarker of response or resistance to lenalidomide and pomalidomide requires use of standardized reagents and understanding of gene complexity. Br J Haematol (2013) 1.07
IL-1beta induces a MyD88-dependent and ceramide-mediated activation of Src in anterior hypothalamic neurons. J Neurochem (2006) 1.06
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Selective stabilization of self-assembled hydrogen-bonded molecular capsules through π-π interactions. J Am Chem Soc (2012) 1.05
The brain galanin receptors: targets for novel antidepressant drugs. CNS Neurol Disord Drug Targets (2007) 1.04
Fluorescent sensors for organophosphorus nerve agent mimics. J Am Chem Soc (2006) 1.04
Hydrocarbon binding inside a hexameric pyrogallol[4]arene capsule. Org Lett (2005) 1.03
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Neuropeptide expression in rats exposed to chronic mild stresses. Psychopharmacology (Berl) (2004) 1.02
Assembly of resorcinarene capsules in wet solvents. J Am Chem Soc (2003) 1.01
High-throughput FRET assay yields allosteric SERCA activators. J Biomol Screen (2012) 1.01
Repeated phencyclidine administration alters glutamate release and decreases GABA markers in the prefrontal cortex of rats. Neuropharmacology (2011) 1.00
A synthetic mimic of protein inner space: buried polar interactions in a deep water-soluble host. J Am Chem Soc (2006) 1.00
A role for galanin in antidepressant actions with a focus on the dorsal raphe nucleus. Proc Natl Acad Sci U S A (2005) 0.99
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Galanin acts at GalR1 receptors in spinal antinociception: synergy with morphine and AP-5. J Pharmacol Exp Ther (2003) 0.98
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Self-fulfilling cavitands: packing alkyl chains into small spaces. Proc Natl Acad Sci U S A (2006) 0.97
A synthetic receptor for choline and carnitine. J Am Chem Soc (2002) 0.97
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A deep, water-soluble cavitand acts as a phase-transfer catalyst for hydrophobic species. Angew Chem Int Ed Engl (2006) 0.96
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A small molecule that mimics the BB-loop in the Toll interleukin-1 (IL-1) receptor domain of MyD88 attenuates staphylococcal enterotoxin B-induced pro-inflammatory cytokine production and toxicity in mice. J Biol Chem (2011) 0.95
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