Published in Development on February 15, 2006
Scratching the surface of skin development. Nature (2007) 4.61
Wnt/beta-catenin signaling directs multiple stages of tooth morphogenesis. Dev Biol (2007) 2.26
Reciprocal requirements for EDA/EDAR/NF-kappaB and Wnt/beta-catenin signaling pathways in hair follicle induction. Dev Cell (2009) 2.17
Growth retardation and altered autonomic control in mice lacking brain serotonin. Proc Natl Acad Sci U S A (2009) 2.01
Activation of beta-catenin signaling programs embryonic epidermis to hair follicle fate. Development (2008) 1.96
Generation of the primary hair follicle pattern. Proc Natl Acad Sci U S A (2006) 1.72
Analysis of the temporal requirement for eda in hair and sweat gland development. J Invest Dermatol (2008) 1.55
Zebrafish eda and edar mutants reveal conserved and ancestral roles of ectodysplasin signaling in vertebrates. PLoS Genet (2008) 1.48
Mesenchymal-epithelial interactions during hair follicle morphogenesis and cycling. Semin Cell Dev Biol (2012) 1.41
EDA signaling and skin appendage development. Cell Cycle (2006) 1.39
Frequent deregulations in the hedgehog signaling network and cross-talks with the epidermal growth factor receptor pathway involved in cancer progression and targeted therapies. Pharmacol Rev (2010) 1.33
Dlx3 is a crucial regulator of hair follicle differentiation and cycling. Development (2008) 1.32
The interfollicular epidermis of adult mouse tail comprises two distinct cell lineages that are differentially regulated by Wnt, Edaradd, and Lrig1. Stem Cell Reports (2013) 1.20
Epithelial stratification and placode invagination are separable functions in early morphogenesis of the molar tooth. Development (2016) 1.14
Receptor activator of NF-kappaB (RANK) stimulates the proliferation of epithelial cells of the epidermo-pilosebaceous unit. Proc Natl Acad Sci U S A (2011) 1.13
Keratinocyte-specific ablation of the NF-κB regulatory protein A20 (TNFAIP3) reveals a role in the control of epidermal homeostasis. Cell Death Differ (2011) 1.13
Fgf20 governs formation of primary and secondary dermal condensations in developing hair follicles. Genes Dev (2013) 1.10
Ectodysplasin regulates the lymphotoxin-beta pathway for hair differentiation. Proc Natl Acad Sci U S A (2006) 1.04
The Edar subfamily in feather placode formation. Dev Biol (2007) 1.04
Involvement of the Edar signaling in the control of hair follicle involution (catagen). Am J Pathol (2006) 1.01
Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm. BMC Dev Biol (2009) 0.99
Signaling involved in hair follicle morphogenesis and development. Int J Mol Sci (2014) 0.97
Epidermal patterning and induction of different hair types during mouse embryonic development. Birth Defects Res C Embryo Today (2009) 0.95
Cyclic expression of lhx2 regulates hair formation. PLoS Genet (2010) 0.95
Biological activity of ectodysplasin A is conditioned by its collagen and heparan sulfate proteoglycan-binding domains. J Biol Chem (2009) 0.92
Involvement of Wnt, Eda and Shh at defined stages of sweat gland development. Development (2014) 0.91
Pharmacologic inhibition of JAK-STAT signaling promotes hair growth. Sci Adv (2015) 0.89
MicroRNA-214 controls skin and hair follicle development by modulating the activity of the Wnt pathway. J Cell Biol (2014) 0.87
Signaling Networks among Stem Cell Precursors, Transit-Amplifying Progenitors, and their Niche in Developing Hair Follicles. Cell Rep (2016) 0.87
The dermal papilla: an instructive niche for epithelial stem and progenitor cells in development and regeneration of the hair follicle. Cold Spring Harb Perspect Med (2014) 0.84
Identification of ectodysplasin-A receptor gene deletion at 2q12.2 and a potential autosomal MR locus. Eur J Hum Genet (2008) 0.82
E2 Polyubiquitin-conjugating enzyme Ubc13 in keratinocytes is essential for epidermal integrity. J Biol Chem (2010) 0.81
Inflammatory mediator TAK1 regulates hair follicle morphogenesis and anagen induction shown by using keratinocyte-specific TAK1-deficient mice. PLoS One (2010) 0.80
Pharmacological stimulation of Edar signaling in the adult enhances sebaceous gland size and function. J Invest Dermatol (2014) 0.79
Candidate EDA targets revealed by expression profiling of primary keratinocytes from Tabby mutant mice. Gene (2008) 0.79
Testing chemotherapeutic agents in the feather follicle identifies a selective blockade of cell proliferation and a key role for sonic hedgehog signaling in chemotherapy-induced tissue damage. J Invest Dermatol (2014) 0.79
Generation and characterization of function-blocking anti-ectodysplasin A (EDA) monoclonal antibodies that induce ectodermal dysplasia. J Biol Chem (2014) 0.78
Wnt5a attenuates hypoxia-induced pulmonary arteriolar remodeling and right ventricular hypertrophy in mice. Exp Biol Med (Maywood) (2015) 0.78
Disrupted ectodermal organ morphogenesis in mice with a conditional histone deacetylase 1, 2 deletion in the epidermis. J Invest Dermatol (2013) 0.78
Ectodysplasin/NF-κB Promotes Mammary Cell Fate via Wnt/β-catenin Pathway. PLoS Genet (2015) 0.78
Direct reprogramming of human fibroblasts into sweat gland-like cells. Cell Cycle (2015) 0.77
Hair follicle morphogenesis and epidermal homeostasis in we/we wal/wal mice with postnatal alopecia. Histochem Cell Biol (2014) 0.76
A Cascade of Wnt, Eda, and Shh Signaling Is Essential for Touch Dome Merkel Cell Development. PLoS Genet (2016) 0.75
Linking morphogen and chromatin in the hair follicle. Dev Cell (2013) 0.75
Ectodysplasin A Pathway Contributes to Human and Murine Skin Repair. J Invest Dermatol (2016) 0.75
Developing an ancient epithelial appendage: FGF signalling regulates early tail denticle formation in sharks. Evodevo (2017) 0.75
Rimonabant reduces keratinocyte viability by induction of apoptosis and exerts topical anti-inflammatory activity in mice. Br J Pharmacol (2011) 0.75
Hierarchical patterning modes orchestrate hair follicle morphogenesis. PLoS Biol (2017) 0.75
IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis. Cell (2007) 7.74
Melanin pigmentation in mammalian skin and its hormonal regulation. Physiol Rev (2004) 5.89
BAFF AND APRIL: a tutorial on B cell survival. Annu Rev Immunol (2001) 4.87
Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren's syndrome. J Clin Invest (2002) 4.14
Cracking the BAFF code. Nat Rev Immunol (2009) 3.95
The molecular architecture of the TNF superfamily. Trends Biochem Sci (2002) 3.39
Molecular principles of hair follicle induction and morphogenesis. Bioessays (2005) 3.08
Genome-wide association study in alopecia areata implicates both innate and adaptive immunity. Nature (2010) 2.85
The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex. J Biol Chem (2002) 2.75
Interactions of tumor necrosis factor (TNF) and TNF receptor family members in the mouse and human. J Biol Chem (2006) 2.75
T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes. Nature (2009) 2.59
Alopecia areata. N Engl J Med (2012) 2.56
A nuclear poly(ADP-ribose)-dependent signalosome confers DNA damage-induced IkappaB kinase activation. Mol Cell (2009) 2.56
The hair follicle as a dynamic miniorgan. Curr Biol (2009) 2.52
Two adjacent trimeric Fas ligands are required for Fas signaling and formation of a death-inducing signaling complex. Mol Cell Biol (2003) 2.50
Exploring the "hair growth-wound healing connection": anagen phase promotes wound re-epithelialization. J Invest Dermatol (2010) 2.48
Two distinct mechanisms underlie progesterone-induced proliferation in the mammary gland. Proc Natl Acad Sci U S A (2010) 2.45
APRIL is critical for plasmablast survival in the bone marrow and poorly expressed by early-life bone marrow stromal cells. Blood (2008) 2.44
TL1A-DR3 interaction regulates Th17 cell function and Th17-mediated autoimmune disease. J Exp Med (2008) 2.33
IL-15/IL-15 receptor biology: a guided tour through an expanding universe. Cytokine Growth Factor Rev (2006) 2.29
Vascular endothelial cell-specific NF-kappaB suppression attenuates hypertension-induced renal damage. Circ Res (2007) 2.25
Human hair follicles display a functional equivalent of the hypothalamic-pituitary-adrenal axis and synthesize cortisol. FASEB J (2005) 2.23
Reciprocal requirements for EDA/EDAR/NF-kappaB and Wnt/beta-catenin signaling pathways in hair follicle induction. Dev Cell (2009) 2.17
Malt1 ubiquitination triggers NF-kappaB signaling upon T-cell activation. EMBO J (2007) 2.16
TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNFalpha. J Cell Biol (2008) 2.11
Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin. Genes Dev (2006) 2.10
Progesterone/RANKL is a major regulatory axis in the human breast. Sci Transl Med (2013) 2.09
BAFF, APRIL and their receptors: structure, function and signaling. Semin Immunol (2006) 2.09
Identification of proteoglycans as the APRIL-specific binding partners. J Exp Med (2005) 2.03
Elevated NF-kappaB p50 complex formation and Bcl-3 expression in classical Hodgkin, anaplastic large-cell, and other peripheral T-cell lymphomas. Blood (2005) 2.00
IL-15 constrains mast cell-dependent antibacterial defenses by suppressing chymase activities. Nat Med (2007) 2.00
Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-kappa B. EMBO J (2002) 2.00
Purification and characterization of the human elongator complex. J Biol Chem (2001) 1.97
Requirement of Hsp90 activity for IkappaB kinase (IKK) biosynthesis and for constitutive and inducible IKK and NF-kappaB activation. Oncogene (2004) 1.87
TACI, unlike BAFF-R, is solely activated by oligomeric BAFF and APRIL to support survival of activated B cells and plasmablasts. Blood (2007) 1.85
Hair follicle pigmentation. J Invest Dermatol (2005) 1.84
A pervasive role of ubiquitin conjugation in activation and termination of IkappaB kinase pathways. EMBO Rep (2005) 1.79
A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation. Mol Cell (2010) 1.79
Key role of CRF in the skin stress response system. Endocr Rev (2013) 1.77
The cutaneous serotoninergic/melatoninergic system: securing a place under the sun. FASEB J (2005) 1.77
Permanent correction of an inherited ectodermal dysplasia with recombinant EDA. Nat Med (2003) 1.75
TWEAK, via its receptor Fn14, is a novel regulator of mesenchymal progenitor cells and skeletal muscle regeneration. EMBO J (2006) 1.73
Differential expression of HPA axis homolog in the skin. Mol Cell Endocrinol (2006) 1.72
Retracted A promiscuous liaison between IL-15 receptor and Axl receptor tyrosine kinase in cell death control. EMBO J (2005) 1.72
Neuroimmunology of stress: skin takes center stage. J Invest Dermatol (2006) 1.72
Generation of the primary hair follicle pattern. Proc Natl Acad Sci U S A (2006) 1.72
The interleukin-15/interleukin-15 receptor system as a model for juxtacrine and reverse signaling. Bioessays (2006) 1.70
Opposing roles of NF-κB in anti-cancer treatment outcome unveiled by cross-species investigations. Genes Dev (2011) 1.69
Further exploring the brain-skin connection: stress worsens dermatitis via substance P-dependent neurogenic inflammation in mice. J Invest Dermatol (2007) 1.67
Regulation of human epidermal melanocyte biology by beta-endorphin. J Invest Dermatol (2003) 1.66
Efficient generation of human alloantigen-specific CD4+ regulatory T cells from naive precursors by CD40-activated B cells. Blood (2008) 1.64
Fas ligand elicits a caspase-independent proinflammatory response in human keratinocytes: implications for dermatitis. J Invest Dermatol (2006) 1.64
Requirement of nuclear factor-kappaB in angiotensin II- and isoproterenol-induced cardiac hypertrophy in vivo. Circulation (2005) 1.59
Neuronal plasticity of the "brain-skin connection": stress-triggered up-regulation of neuropeptides in dorsal root ganglia and skin via nerve growth factor-dependent pathways. J Mol Med (Berl) (2007) 1.58
Lymphocytes, neuropeptides, and genes involved in alopecia areata. J Clin Invest (2007) 1.56
Cylindroma as tumor of hair follicle origin. J Invest Dermatol (2006) 1.56
TRAIL receptor-mediated JNK activation and Bim phosphorylation critically regulate Fas-mediated liver damage and lethality. J Clin Invest (2006) 1.55
Lymphotoxin and lipopolysaccharide induce NF-kappaB-p52 generation by a co-translational mechanism. EMBO Rep (2003) 1.55
IκB-ζ controls the constitutive NF-κB target gene network and survival of ABC DLBCL. Blood (2013) 1.55
Ectodysplasin has a dual role in ectodermal organogenesis: inhibition of Bmp activity and induction of Shh expression. Development (2007) 1.53
Ectodysplasin A1 promotes placodal cell fate during early morphogenesis of ectodermal appendages. Development (2004) 1.53
Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2. Mol Cell Biol (2006) 1.52
Mast cells are required for normal healing of skin wounds in mice. FASEB J (2006) 1.50
APRIL secreted by neutrophils binds to heparan sulfate proteoglycans to create plasma cell niches in human mucosa. J Clin Invest (2008) 1.50
Circadian clock genes contribute to the regulation of hair follicle cycling. PLoS Genet (2009) 1.49
Beyond wavy hairs: the epidermal growth factor receptor and its ligands in skin biology and pathology. Am J Pathol (2008) 1.47
TNF deficiency fails to protect BAFF transgenic mice against autoimmunity and reveals a predisposition to B cell lymphoma. J Immunol (2004) 1.47
Differential expression of a cutaneous corticotropin-releasing hormone system. Endocrinology (2003) 1.46
Corticotropin releasing hormone and the skin. Front Biosci (2006) 1.45
On the role of melatonin in skin physiology and pathology. Endocrine (2005) 1.43
Thyrotropin-releasing hormone selectively stimulates human hair follicle pigmentation. J Invest Dermatol (2011) 1.43
Immunophenotyping of the human bulge region: the quest to define useful in situ markers for human epithelial hair follicle stem cells and their niche. Exp Dermatol (2008) 1.43
Melanocortin receptor ligands: new horizons for skin biology and clinical dermatology. J Invest Dermatol (2006) 1.41
Human cytomegalovirus glycoprotein UL141 targets the TRAIL death receptors to thwart host innate antiviral defenses. Cell Host Microbe (2013) 1.41
Functional activity of serotoninergic and melatoninergic systems expressed in the skin. J Cell Physiol (2003) 1.41
The IkappaB kinase complex and NF-kappaB act as master regulators of lipopolysaccharide-induced gene expression and control subordinate activation of AP-1. Mol Cell Biol (2004) 1.39
Dilated cardiomyopathy in mice deficient for the lysosomal cysteine peptidase cathepsin L. Proc Natl Acad Sci U S A (2002) 1.37
Molecular biology of hair morphogenesis: development and cycling. J Exp Zool B Mol Dev Evol (2003) 1.36
TACI, an enigmatic BAFF/APRIL receptor, with new unappreciated biochemical and biological properties. Cytokine Growth Factor Rev (2008) 1.35
Differential insertion of GPI-anchored GFPs into lipid rafts of live cells. FASEB J (2004) 1.33
Serotoninergic and melatoninergic systems are fully expressed in human skin. FASEB J (2002) 1.33
Neuropeptide control mechanisms in cutaneous biology: physiological and clinical significance. J Invest Dermatol (2006) 1.33
The IκB kinase complex in NF-κB regulation and beyond. EMBO Rep (2013) 1.32
Loss of PU.1 expression is associated with defective immunoglobulin transcription in Hodgkin and Reed-Sternberg cells of classical Hodgkin disease. Blood (2002) 1.32
Plasticity and cytokinetic dynamics of the hair follicle mesenchyme: implications for hair growth control. J Invest Dermatol (2003) 1.32
BAFF is a survival and maturation factor for mouse B cells. Eur J Immunol (2002) 1.31
BAFF production by antigen-presenting cells provides T cell co-stimulation. Int Immunol (2004) 1.29
A hot new twist to hair biology: involvement of vanilloid receptor-1 (VR1/TRPV1) signaling in human hair growth control. Am J Pathol (2005) 1.27
Migration of melanoblasts into the developing murine hair follicle is accompanied by transient c-Kit expression. J Histochem Cytochem (2002) 1.26
Tetrameric oligomerization of IkappaB kinase gamma (IKKgamma) is obligatory for IKK complex activity and NF-kappaB activation. Mol Cell Biol (2003) 1.26
Burden of hair loss: stress and the underestimated psychosocial impact of telogen effluvium and androgenetic alopecia. J Invest Dermatol (2004) 1.24
Runx1 directly promotes proliferation of hair follicle stem cells and epithelial tumor formation in mouse skin. Mol Cell Biol (2010) 1.23
Exploring the role of stem cells in cutaneous wound healing. Exp Dermatol (2009) 1.23
The sunburn response in human skin is characterized by sequential eicosanoid profiles that may mediate its early and late phases. FASEB J (2009) 1.22
Stress inhibits hair growth in mice by induction of premature catagen development and deleterious perifollicular inflammatory events via neuropeptide substance P-dependent pathways. Am J Pathol (2003) 1.22