Stephen M Cohen

Author PubWeight™ 199.43‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Principles of microRNA-target recognition. PLoS Biol 2005 23.70
2 bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila. Cell 2003 22.14
3 microRNA functions. Annu Rev Cell Dev Biol 2007 15.74
4 Animal MicroRNAs confer robustness to gene expression and have a significant impact on 3'UTR evolution. Cell 2005 15.38
5 Identification of Drosophila MicroRNA targets. PLoS Biol 2003 12.72
6 Isolation of microRNA targets by miRNP immunopurification. RNA 2007 5.50
7 Drosophila's insulin/PI3-kinase pathway coordinates cellular metabolism with nutritional conditions. Dev Cell 2002 4.85
8 The conserved microRNA miR-8 tunes atrophin levels to prevent neurodegeneration in Drosophila. Cell 2007 4.00
9 The Hippo pathway regulates the bantam microRNA to control cell proliferation and apoptosis in Drosophila. Cell 2006 3.81
10 Genome-wide analysis of mRNAs regulated by Drosha and Argonaute proteins in Drosophila melanogaster. Mol Cell Biol 2006 3.80
11 Tumor suppressor properties of the ESCRT-II complex component Vps25 in Drosophila. Dev Cell 2005 2.81
12 On the mechanism of wing size determination in fly development. Proc Natl Acad Sci U S A 2007 2.62
13 Mei-P26 regulates microRNAs and cell growth in the Drosophila ovarian stem cell lineage. Nature 2008 2.54
14 MicroRNAs and gene regulatory networks: managing the impact of noise in biological systems. Genes Dev 2010 2.51
15 Temporal reciprocity of miRNAs and their targets during the maternal-to-zygotic transition in Drosophila. Curr Biol 2008 2.47
16 A single Hox locus in Drosophila produces functional microRNAs from opposite DNA strands. Genes Dev 2008 2.45
17 Nutritional control of protein biosynthetic capacity by insulin via Myc in Drosophila. Cell Metab 2008 2.32
18 4E-BP functions as a metabolic brake used under stress conditions but not during normal growth. Genes Dev 2005 2.28
19 Drosophila lacking microRNA miR-278 are defective in energy homeostasis. Genes Dev 2006 2.26
20 Regulation of tissue growth through nutrient sensing. Annu Rev Genet 2009 2.18
21 HSPG modification by the secreted enzyme Notum shapes the Wingless morphogen gradient. Dev Cell 2002 2.03
22 Connecting proliferation and apoptosis in development and disease. Nat Rev Mol Cell Biol 2004 1.97
23 Re-evaluating AKT regulation: role of TOR complex 2 in tissue growth. Genes Dev 2007 1.83
24 microRNA miR-14 acts to modulate a positive autoregulatory loop controlling steroid hormone signaling in Drosophila. Genes Dev 2007 1.80
25 Wingless and Notch signaling provide cell survival cues and control cell proliferation during wing development. Development 2003 1.72
26 Opposing activities of Dally-like glypican at high and low levels of Wingless morphogen activity. Dev Cell 2004 1.69
27 The bantam gene regulates Drosophila growth. Genetics 2002 1.62
28 MicroRNAs in neurodegeneration. Curr Opin Neurobiol 2008 1.62
29 Drosophila Melted modulates FOXO and TOR activity. Dev Cell 2005 1.59
30 Short-range cell interactions and cell survival in the Drosophila wing. Dev Cell 2002 1.57
31 Towards a complete description of the microRNA complement of animal genomes. Genome Biol 2003 1.49
32 Slik Sterile-20 kinase regulates Moesin activity to promote epithelial integrity during tissue growth. Genes Dev 2004 1.38
33 Identification of novel Drosophila melanogaster microRNAs. PLoS One 2007 1.28
34 Recombinase-mediated cassette exchange provides a versatile platform for gene targeting: knockout of miR-31b. Genetics 2009 1.26
35 Immunopurification of Ago1 miRNPs selects for a distinct class of microRNA targets. Proc Natl Acad Sci U S A 2009 1.26
36 Drosophila microRNAs 263a/b confer robustness during development by protecting nascent sense organs from apoptosis. PLoS Biol 2010 1.26
37 MAP4K3 regulates body size and metabolism in Drosophila. Dev Biol 2010 1.24
38 On the role of glypicans in the process of morphogen gradient formation. Dev Biol 2006 1.18
39 TOR complex 2 is needed for cell cycle progression and anchorage-independent growth of MCF7 and PC3 tumor cells. BMC Cancer 2008 1.18
40 A genetic screen in Drosophila for identifying novel components of the hedgehog signaling pathway. Genetics 2005 1.14
41 Drosophila miR-14 regulates insulin production and metabolism through its target, sugarbabe. Genes Dev 2010 1.10
42 Drosophila miR-124 regulates neuroblast proliferation through its target anachronism. Development 2012 1.04
43 MAPK/ERK signaling regulates insulin sensitivity to control glucose metabolism in Drosophila. PLoS Genet 2011 1.03
44 Gain-of-function screen for genes that affect Drosophila muscle pattern formation. PLoS Genet 2005 1.02
45 Boundary formation in the Drosophila wing: functional dissection of Capricious and Tartan. Dev Dyn 2005 1.01
46 The Drosophila sterile-20 kinase slik controls cell proliferation and apoptosis during imaginal disc development. PLoS Biol 2003 1.00
47 Distal antenna and distal antenna related encode nuclear proteins containing pipsqueak motifs involved in antenna development in Drosophila. Development 2003 0.99
48 Notch-mediated repression of bantam miRNA contributes to boundary formation in the Drosophila wing. Development 2011 0.99
49 Proximodistal subdivision of Drosophila legs and wings: the elbow-no ocelli gene complex. Development 2004 0.98
50 A naturally occurring alternative product of the mastermind locus that represses notch signalling. Mech Dev 2002 0.98
51 Mutual repression by bantam miRNA and Capicua links the EGFR/MAPK and Hippo pathways in growth control. Curr Biol 2012 0.98
52 A re-evaluation of the contributions of Apterous and Notch to the dorsoventral lineage restriction boundary in the Drosophila wing. Development 2003 0.98
53 molting defective is required for ecdysone biosynthesis. Dev Biol 2005 0.97
54 Oncogenic cooperation between SOCS family proteins and EGFR identified using a Drosophila epithelial transformation model. Genes Dev 2012 0.97
55 Repression of Teashirt marks the initiation of wing development. Development 2002 0.97
56 The miRNA machinery targets Mei-P26 and regulates Myc protein levels in the Drosophila wing. EMBO J 2010 0.97
57 MicroRNA transgene overexpression complements deficiency-based modifier screens in Drosophila. Genetics 2011 0.96
58 Protocols for use of homologous recombination gene targeting to produce microRNA mutants in Drosophila. Methods Mol Biol 2011 0.94
59 Drosophila egghead encodes a beta 1,4-mannosyltransferase predicted to form the immediate precursor glycosphingolipid substrate for brainiac. J Biol Chem 2002 0.94
60 Egghead and brainiac are essential for glycosphingolipid biosynthesis in vivo. J Biol Chem 2004 0.92
61 Not miR-ly muscular: microRNAs and muscle development. Genes Dev 2005 0.92
62 Structural insights into the Notch-modifying glycosyltransferase Fringe. Nat Struct Mol Biol 2006 0.92
63 The Drosophila gene brainiac encodes a glycosyltransferase putatively involved in glycosphingolipid synthesis. J Biol Chem 2002 0.91
64 ER stress potentiates insulin resistance through PERK-mediated FOXO phosphorylation. Genes Dev 2013 0.90
65 The oscillating miRNA 959-964 cluster impacts Drosophila feeding time and other circadian outputs. Cell Metab 2012 0.90
66 Spatial and temporal regulation of the homeotic selector gene Antennapedia is required for the establishment of leg identity in Drosophila. Dev Biol 2004 0.89
67 An evaluation of the efficacy of a cyclosporine-based dry eye therapy when used with marketed artificial tears as supportive therapy in dry eye. Eye Contact Lens 2006 0.89
68 Glycosphingolipids with extended sugar chain have specialized functions in development and behavior of Drosophila. Dev Biol 2007 0.89
69 Osa modulates the expression of Apterous target genes in the Drosophila wing. Mech Dev 2004 0.87
70 Maternal loss of miRNAs leads to increased variance in primordial germ cell numbers in Drosophila melanogaster. G3 (Bethesda) 2013 0.86
71 Perspective: follow the money: the implications of medical schools' funds flow models. Acad Med 2012 0.85
72 Drosophila Minus is required for cell proliferation and influences Cyclin E turnover. Genes Dev 2009 0.84
73 The Hippo pathway acts via p53 and microRNAs to control proliferation and proapoptotic gene expression during tissue growth. Biol Open 2013 0.83
74 miR-124 controls male reproductive success in Drosophila. Elife 2013 0.82
75 miR-989 is required for border cell migration in the Drosophila ovary. PLoS One 2013 0.82
76 Glycosphingolipids control the extracellular gradient of the Drosophila EGFR ligand Gurken. Development 2009 0.81
77 TORCing up metabolic control in the brain. Cell Metab 2008 0.80
78 Time is of the essence: microRNAs and age-associated neurodegeneration. Cell Res 2012 0.80
79 Ligand-binding and signaling properties of the Ax[M1] form of Notch. Mech Dev 2005 0.79
80 Rescue of Drosophila Melanogaster l(2)35Aa lethality is only mediated by polypeptide GalNAc-transferase pgant35A, but not by the evolutionary conserved human ortholog GalNAc-transferase-T11. Glycoconj J 2010 0.78
81 Notch signaling: filopodia dynamics confer robustness. Curr Biol 2010 0.76
82 Developmental biology: long-range signalling by touch. Nature 2003 0.75
83 The secret life of Smoothened. Dev Cell 2003 0.75