| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Biological, clinical and population relevance of 95 loci for blood lipids.
|
Nature
|
2010
|
28.21
|
|
2
|
Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol.
|
Lancet
|
2002
|
23.18
|
|
3
|
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.
|
Nat Genet
|
2010
|
23.08
|
|
4
|
Hundreds of variants clustered in genomic loci and biological pathways affect human height.
|
Nature
|
2010
|
20.01
|
|
5
|
Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study.
|
Lancet
|
2012
|
12.10
|
|
6
|
Third universal definition of myocardial infarction.
|
J Am Coll Cardiol
|
2012
|
8.59
|
|
7
|
Third universal definition of myocardial infarction.
|
Circulation
|
2012
|
8.47
|
|
8
|
Third universal definition of myocardial infarction.
|
Eur Heart J
|
2012
|
7.98
|
|
9
|
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.
|
Nat Genet
|
2010
|
7.94
|
|
10
|
Guidelines for the diagnosis and treatment of chronic heart failure: executive summary (update 2005): The Task Force for the Diagnosis and Treatment of Chronic Heart Failure of the European Society of Cardiology.
|
Eur Heart J
|
2005
|
7.75
|
|
11
|
Large-scale association analysis identifies new risk loci for coronary artery disease.
|
Nat Genet
|
2012
|
7.59
|
|
12
|
Cardiovascular morbidity and mortality in patients with diabetes in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol.
|
Lancet
|
2002
|
6.87
|
|
13
|
A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.
|
Nat Genet
|
2009
|
6.31
|
|
14
|
A multilocus genetic risk score for coronary heart disease: case-control and prospective cohort analyses.
|
Lancet
|
2010
|
6.07
|
|
15
|
Prognostic significance of left ventricular mass change during treatment of hypertension.
|
JAMA
|
2004
|
3.88
|
|
16
|
Albuminuria and cardiovascular risk in hypertensive patients with left ventricular hypertrophy: the LIFE study.
|
Ann Intern Med
|
2003
|
3.78
|
|
17
|
Effects of losartan on cardiovascular morbidity and mortality in patients with isolated systolic hypertension and left ventricular hypertrophy: a Losartan Intervention for Endpoint Reduction (LIFE) substudy.
|
JAMA
|
2002
|
3.70
|
|
18
|
Regression of electrocardiographic left ventricular hypertrophy during antihypertensive treatment and the prediction of major cardiovascular events.
|
JAMA
|
2004
|
3.68
|
|
19
|
State of the art: using natriuretic peptide levels in clinical practice.
|
Eur J Heart Fail
|
2008
|
3.35
|
|
20
|
Angiotensin II receptor blockade reduces new-onset atrial fibrillation and subsequent stroke compared to atenolol: the Losartan Intervention For End Point Reduction in Hypertension (LIFE) study.
|
J Am Coll Cardiol
|
2005
|
3.27
|
|
21
|
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
|
Nat Genet
|
2013
|
3.25
|
|
22
|
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.
|
PLoS Genet
|
2012
|
3.21
|
|
23
|
The impact of serum uric acid on cardiovascular outcomes in the LIFE study.
|
Kidney Int
|
2004
|
2.96
|
|
24
|
Levosimendan vs dobutamine for patients with acute decompensated heart failure: the SURVIVE Randomized Trial.
|
JAMA
|
2007
|
2.90
|
|
25
|
Reduction in albuminuria translates to reduction in cardiovascular events in hypertensive patients: losartan intervention for endpoint reduction in hypertension study.
|
Hypertension
|
2005
|
2.69
|
|
26
|
The Anglo-Scandinavian Cardiac Outcomes Trial lipid lowering arm: extended observations 2 years after trial closure.
|
Eur Heart J
|
2008
|
2.65
|
|
27
|
Regression of hypertensive left ventricular hypertrophy by losartan compared with atenolol: the Losartan Intervention for Endpoint Reduction in Hypertension (LIFE) trial.
|
Circulation
|
2004
|
2.56
|
|
28
|
Safety and feasibility of catheter-based local intracoronary vascular endothelial growth factor gene transfer in the prevention of postangioplasty and in-stent restenosis and in the treatment of chronic myocardial ischemia: phase II results of the Kuopio Angiogenesis Trial (KAT).
|
Circulation
|
2003
|
2.48
|
|
29
|
Genetically determined height and coronary artery disease.
|
N Engl J Med
|
2015
|
2.24
|
|
30
|
Multifactorial intervention to prevent recurrent cardiovascular events in patients 75 years or older: the Drugs and Evidence-Based Medicine in the Elderly (DEBATE) study: a randomized, controlled trial.
|
Am Heart J
|
2006
|
2.19
|
|
31
|
Effects of losartan or atenolol in hypertensive patients without clinically evident vascular disease: a substudy of the LIFE randomized trial.
|
Ann Intern Med
|
2003
|
2.09
|
|
32
|
Regression of electrocardiographic left ventricular hypertrophy and decreased incidence of new-onset atrial fibrillation in patients with hypertension.
|
JAMA
|
2006
|
2.00
|
|
33
|
Characteristics, outcomes, and predictors of 1-year mortality in patients hospitalized for acute heart failure.
|
Eur Heart J
|
2006
|
1.80
|
|
34
|
A novel mutation, Ser143Pro, in the lamin A/C gene is common in finnish patients with familial dilated cardiomyopathy.
|
Eur Heart J
|
2004
|
1.78
|
|
35
|
Lowered B-type natriuretic peptide in response to levosimendan or dobutamine treatment is associated with improved survival in patients with severe acutely decompensated heart failure.
|
J Am Coll Cardiol
|
2009
|
1.76
|
|
36
|
Evidence-based use of levosimendan in different clinical settings.
|
Eur Heart J
|
2006
|
1.73
|
|
37
|
Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.
|
Nat Genet
|
2013
|
1.72
|
|
38
|
Microalbuminuria in hypertensive patients with electrocardiographic left ventricular hypertrophy: the LIFE study.
|
J Hypertens
|
2002
|
1.69
|
|
39
|
Pulse pressure/stroke index and left ventricular geometry and function: the LIFE Study.
|
J Hypertens
|
2003
|
1.69
|
|
40
|
Predictive value of electrocardiographic QT interval and T-wave morphology parameters for all-cause and cardiovascular mortality in a general population sample.
|
Heart Rhythm
|
2009
|
1.68
|
|
41
|
Progression of atherosclerosis is associated with variation in the alpha1-antitrypsin gene.
|
Arterioscler Thromb Vasc Biol
|
2003
|
1.65
|
|
42
|
Coronary artery disease-associated locus on chromosome 9p21 and early markers of atherosclerosis.
|
Arterioscler Thromb Vasc Biol
|
2008
|
1.62
|
|
43
|
Relationship of common candidate gene variants to electrocardiographic T-wave peak to T-wave end interval and T-wave morphology parameters.
|
Heart Rhythm
|
2010
|
1.58
|
|
44
|
Incidence of atrial fibrillation in relation to changing heart rate over time in hypertensive patients: the LIFE study.
|
Circ Arrhythm Electrophysiol
|
2008
|
1.56
|
|
45
|
Clinical picture and risk prediction of short-term mortality in cardiogenic shock.
|
Eur J Heart Fail
|
2015
|
1.56
|
|
46
|
Does albuminuria predict cardiovascular outcome on treatment with losartan versus atenolol in hypertension with left ventricular hypertrophy? A LIFE substudy.
|
J Hypertens
|
2004
|
1.53
|
|
47
|
Stroke reduction in hypertensive adults with cardiac hypertrophy randomized to losartan versus atenolol: the Losartan Intervention For Endpoint reduction in hypertension study.
|
Hypertension
|
2004
|
1.52
|
|
48
|
Risk of new-onset diabetes in the Losartan Intervention For Endpoint reduction in hypertension study.
|
J Hypertens
|
2002
|
1.51
|
|
49
|
Pulse pressure and effects of losartan or atenolol in patients with hypertension and left ventricular hypertrophy.
|
Hypertension
|
2005
|
1.49
|
|
50
|
Effects of losartan compared with atenolol on lipids in patients with hypertension and left ventricular hypertrophy: the Losartan Intervention For Endpoint reduction in hypertension study.
|
J Hypertens
|
2009
|
1.48
|
|
51
|
Early familial dilated cardiomyopathy: identification with determination of disease state parameter from cine MR image data.
|
Radiology
|
2008
|
1.48
|
|
52
|
Characteristics, outcomes, and predictors of mortality at 3 months and 1 year in patients hospitalized for acute heart failure.
|
Eur J Heart Fail
|
2010
|
1.46
|
|
53
|
Clinical impact of 'in-treatment' wall motion abnormalities in hypertensive patients with left ventricular hypertrophy: the LIFE study.
|
J Hypertens
|
2008
|
1.46
|
|
54
|
Beneficial association of β-blocker therapy on recovery from severe acute heart failure treatment: data from the Survival of Patients With Acute Heart Failure in Need of Intravenous Inotropic Support trial.
|
Crit Care Med
|
2011
|
1.45
|
|
55
|
Quantifying cardiac hemodynamic stress and cardiomyocyte damage in ischemic and nonischemic acute heart failure.
|
Circ Heart Fail
|
2011
|
1.44
|
|
56
|
Left atrial systolic force in hypertensive patients with left ventricular hypertrophy: the LIFE study.
|
J Hypertens
|
2008
|
1.44
|
|
57
|
Coronary heart disease: from a disease of middle-aged men in the late 1970s to a disease of elderly women in the 2000s.
|
Eur Heart J
|
2005
|
1.44
|
|
58
|
Regression of electrocardiographic left ventricular hypertrophy during antihypertensive therapy and reduction in sudden cardiac death: the LIFE Study.
|
Circulation
|
2007
|
1.41
|
|
59
|
Prevalence and prognosis of ECG abnormalities in normotensive and hypertensive individuals.
|
J Hypertens
|
2016
|
1.41
|
|
60
|
Electrocardiographic strain pattern and left ventricular diastolic function in hypertensive patients with left ventricular hypertrophy: the LIFE study.
|
J Hypertens
|
2006
|
1.39
|
|
61
|
Magnetocardiographic indices of left ventricular hypertrophy.
|
J Hypertens
|
2002
|
1.38
|
|
62
|
Levosimendan vs. dobutamine: outcomes for acute heart failure patients on beta-blockers in SURVIVE.
|
Eur J Heart Fail
|
2009
|
1.25
|
|
63
|
QRS duration and QT interval predict mortality in hypertensive patients with left ventricular hypertrophy: the Losartan Intervention for Endpoint Reduction in Hypertension Study.
|
Hypertension
|
2004
|
1.25
|
|
64
|
Prognostic risk of atrial fibrillation in acute myocardial infarction complicated by left ventricular dysfunction: the OPTIMAAL experience.
|
Eur Heart J
|
2004
|
1.21
|
|
65
|
Ethnic differences in electrocardiographic criteria for left ventricular hypertrophy: the LIFE study. Losartan Intervention For Endpoint.
|
Am J Hypertens
|
2002
|
1.21
|
|
66
|
APOA5 gene variants, lipoprotein particle distribution, and progression of coronary heart disease: results from the LOCAT study.
|
J Lipid Res
|
2004
|
1.16
|
|
67
|
Cardiovascular morbidity and mortality in hypertensive patients with a history of atrial fibrillation: The Losartan Intervention For End Point Reduction in Hypertension (LIFE) study.
|
J Am Coll Cardiol
|
2005
|
1.14
|
|
68
|
Electrocardiographic strain pattern and prediction of cardiovascular morbidity and mortality in hypertensive patients.
|
Hypertension
|
2004
|
1.12
|
|
69
|
Regression of electrocardiographic left ventricular hypertrophy by losartan versus atenolol: The Losartan Intervention for Endpoint reduction in Hypertension (LIFE) Study.
|
Circulation
|
2003
|
1.12
|
|
70
|
Peroxisome proliferator-activated receptor alpha gene variants influence progression of coronary atherosclerosis and risk of coronary artery disease.
|
Circulation
|
2002
|
1.11
|
|
71
|
Possibilities of multifactorial cardiovascular disease prevention in patients aged 75 and older: a randomized controlled trial: Drugs and Evidence Based Medicine in the Elderly (DEBATE) Study.
|
Eur Heart J
|
2003
|
1.11
|
|
72
|
Prognostic value of cystatin C in acute heart failure in relation to other markers of renal function and NT-proBNP.
|
Eur Heart J
|
2007
|
1.09
|
|
73
|
High prevalence of four long QT syndrome founder mutations in the Finnish population.
|
Ann Med
|
2009
|
1.08
|
|
74
|
Cardiac steatosis associates with visceral obesity in nondiabetic obese men.
|
J Clin Endocrinol Metab
|
2013
|
1.07
|
|
75
|
Markers of renal function and acute kidney injury in acute heart failure: definitions and impact on outcomes of the cardiorenal syndrome.
|
Eur Heart J
|
2010
|
1.06
|
|
76
|
Losartan benefits over atenolol in non-smoking hypertensive patients with left ventricular hypertrophy: the LIFE study.
|
Blood Press
|
2004
|
1.04
|
|
77
|
Prognostic role of pro- and anti-inflammatory cytokines and their polymorphisms in acute decompensated heart failure.
|
Eur J Heart Fail
|
2008
|
1.03
|
|
78
|
Two novel mutations in the beta-myosin heavy chain gene associated with dilated cardiomyopathy.
|
Eur J Heart Fail
|
2004
|
1.03
|
|
79
|
Salivary biomarkers of bacterial burden, inflammatory response, and tissue destruction in periodontitis.
|
J Clin Periodontol
|
2014
|
1.03
|
|
80
|
Cinaciguat, a soluble guanylate cyclase activator, unloads the heart but also causes hypotension in acute decompensated heart failure.
|
Eur Heart J
|
2012
|
1.03
|
|
81
|
A common periodontal pathogen has an adverse association with both acute and stable coronary artery disease.
|
Atherosclerosis
|
2012
|
1.02
|
|
82
|
Association of carotid intima-media thickness with angiographic severity and extent of coronary artery disease.
|
Am J Cardiol
|
2006
|
1.01
|
|
83
|
Electrocardiographic strain pattern and prediction of new-onset congestive heart failure in hypertensive patients: the Losartan Intervention for Endpoint Reduction in Hypertension (LIFE) study.
|
Circulation
|
2005
|
1.00
|
|
84
|
QRS duration predicts sudden cardiac death in hypertensive patients undergoing intensive medical therapy: the LIFE study.
|
Eur Heart J
|
2009
|
1.00
|
|
85
|
Aortic valve sclerosis relates to cardiovascular events in patients with hypertension (a LIFE substudy).
|
Am J Cardiol
|
2005
|
0.97
|
|
86
|
Metabolic syndrome and carotid intima media thickness in the Health 2000 Survey.
|
Atherosclerosis
|
2008
|
0.97
|
|
87
|
Effect of 3 months of antimicrobial treatment with clarithromycin in acute non-q-wave coronary syndrome.
|
Circulation
|
2002
|
0.96
|
|
88
|
Association of paraoxonase-1 activity and concentration with angiographic severity and extent of coronary artery disease.
|
J Am Coll Cardiol
|
2006
|
0.94
|
|
89
|
Relationship of electrocardiographic repolarization measures to echocardiographic left ventricular mass in men with hypertension.
|
J Hypertens
|
2007
|
0.94
|
|
90
|
Interleukin-6 promoter polymorphism and cardiovascular risk factors: the Health 2000 Survey.
|
Atherosclerosis
|
2009
|
0.93
|
|
91
|
R643G polymorphism in PECAM-1 influences transendothelial migration of monocytes and is associated with progression of CHD and CHD events.
|
Atherosclerosis
|
2004
|
0.93
|
|
92
|
Change of left ventricular geometric pattern after 1 year of antihypertensive treatment: the Losartan Intervention For Endpoint reduction in hypertension (LIFE) study.
|
Am Heart J
|
2002
|
0.92
|
|
93
|
Prevalence of ventricular conduction blocks in the resting electrocardiogram in a general population: the Health 2000 Survey.
|
Int J Cardiol
|
2012
|
0.92
|
|
94
|
In-treatment reduced left atrial diameter during antihypertensive treatment is associated with reduced new-onset atrial fibrillation in hypertensive patients with left ventricular hypertrophy: The LIFE Study.
|
Blood Press
|
2010
|
0.92
|
|
95
|
A novel mutation, Arg71Thr, in the delta-sarcoglycan gene is associated with dilated cardiomyopathy.
|
J Mol Med (Berl)
|
2003
|
0.92
|
|
96
|
Cardiac steatosis and left ventricular function in men with metabolic syndrome.
|
J Cardiovasc Magn Reson
|
2013
|
0.92
|
|
97
|
Periodontitis is associated with angiographically verified coronary artery disease.
|
J Clin Periodontol
|
2011
|
0.91
|
|
98
|
Long-term survival after hospitalization for acute heart failure--differences in prognosis of acutely decompensated chronic and new-onset acute heart failure.
|
Int J Cardiol
|
2012
|
0.90
|
|
99
|
Resistin is an indicator of the metabolic syndrome according to five different definitions in the Finnish Health 2000 survey.
|
Metab Syndr Relat Disord
|
2011
|
0.90
|
|
100
|
Serum complement C3/C4 ratio, a novel marker for recurrent cardiovascular events.
|
Am J Cardiol
|
2007
|
0.90
|
|
101
|
Cohort Profile: the Corogene study.
|
Int J Epidemiol
|
2011
|
0.89
|
|
102
|
A novel functional polymorphism in the PECAM-1 gene (53G>A) is associated with progression of atherosclerosis in the LOCAT and REGRESS studies.
|
Atherosclerosis
|
2003
|
0.89
|
|
103
|
Genome-wide meta-analysis of common variant differences between men and women.
|
Hum Mol Genet
|
2012
|
0.88
|
|
104
|
In-treatment midwall and endocardial fractional shortening predict cardiovascular outcome in hypertensive patients with preserved baseline systolic ventricular function: the Losartan Intervention For Endpoint reduction study.
|
J Hypertens
|
2010
|
0.87
|
|
105
|
Effect of losartan versus atenolol on aortic valve sclerosis (a LIFE substudy).
|
Am J Cardiol
|
2004
|
0.86
|
|
106
|
Predictive value of electrocardiographic T-wave morphology parameters and T-wave peak to T-wave end interval for sudden cardiac death in the general population.
|
Circ Arrhythm Electrophysiol
|
2013
|
0.86
|
|
107
|
Echocardiographic wall motion abnormalities in hypertensive patients with electrocardiographic left ventricular hypertrophy: the LIFE Study.
|
Hypertension
|
2003
|
0.85
|
|
108
|
Outcome up to one year following different reperfusion strategies in acute ST-segment elevation myocardial infarction: the Helsinki-Uusimaa Hospital District registry of ST-Elevation Acute Myocardial Infarction (HUS-STEMI).
|
Eur Heart J Acute Cardiovasc Care
|
2013
|
0.85
|
|
109
|
Progressive hypertrophy regression with sustained pressure reduction in hypertension: the Losartan Intervention For Endpoint Reduction study.
|
J Hypertens
|
2002
|
0.85
|
|
110
|
The COACH risk engine: a multistate model for predicting survival and hospitalization in patients with heart failure.
|
Eur J Heart Fail
|
2011
|
0.85
|
|
111
|
[Guidelines for the Diagnosis and Treatment of Chronic Heart Failure: executive summary (update 2005)].
|
Rev Esp Cardiol
|
2005
|
0.85
|
|
112
|
Insulin resistance as predictor of the angiographic severity and extent of coronary artery disease.
|
Ann Med
|
2007
|
0.84
|
|
113
|
Home-measured blood pressure is more strongly associated with atherosclerosis than clinic blood pressure: the Finn-HOME Study.
|
J Hypertens
|
2007
|
0.84
|
|
114
|
Clinical significance of cardiac troponins I and T in acute heart failure.
|
Eur J Heart Fail
|
2008
|
0.84
|
|
115
|
The effects of losartan compared to atenolol on stroke in patients with isolated systolic hypertension and left ventricular hypertrophy. The LIFE study.
|
J Clin Hypertens (Greenwich)
|
2005
|
0.84
|
|
116
|
Blood pressure reduction and antihypertensive medication use in the losartan intervention for endpoint reduction in hypertension (LIFE) study in patients with hypertension and left ventricular hypertrophy.
|
Curr Med Res Opin
|
2007
|
0.84
|
|
117
|
Exercise and cardiovascular outcomes in hypertensive patients in relation to structure and function of left ventricular hypertrophy: the LIFE study.
|
Eur J Cardiovasc Prev Rehabil
|
2009
|
0.84
|
|
118
|
Apolipoprotein E polymorphism is associated with both carotid and coronary atherosclerosis in patients with coronary artery disease.
|
Nutr Metab Cardiovasc Dis
|
2007
|
0.83
|
|
119
|
Prognostic importance of hemoglobin in hypertensive patients with electrocardiographic left ventricular hypertrophy: the Losartan Intervention For End point reduction in hypertension (LIFE) study.
|
Am Heart J
|
2008
|
0.83
|
|
120
|
Proinflammatory HLA-DRB1*01-haplotype predisposes to ST-elevation myocardial infarction.
|
Atherosclerosis
|
2012
|
0.83
|
|
121
|
Is periodontal infection behind the failure of antibiotics to prevent coronary events?
|
Atherosclerosis
|
2006
|
0.83
|
|
122
|
Hereditary hemochromatosis gene (HFE) mutations C282Y, H63D and S65C in patients with idiopathic dilated cardiomyopathy.
|
Eur J Heart Fail
|
2005
|
0.83
|
|
123
|
Prognostic value of changes in the electrocardiographic strain pattern during antihypertensive treatment: the Losartan Intervention for End-Point Reduction in Hypertension Study (LIFE).
|
Circulation
|
2009
|
0.83
|
|
124
|
Low normal level of protein C or of antithrombin increases risk for recurrent cardiovascular events.
|
Blood Coagul Fibrinolysis
|
2005
|
0.82
|
|
125
|
Plasma IgA antibody levels to malondialdehyde acetaldehyde-adducts are associated with inflammatory mediators, obesity and type 2 diabetes.
|
Ann Med
|
2013
|
0.82
|
|
126
|
Relation of twelve-lead electrocardiographic T-wave morphology descriptors to left ventricular mass.
|
Am J Cardiol
|
2002
|
0.82
|
|
127
|
Epicardial fat, cardiac dimensions, and low-grade inflammation in young adult monozygotic twins discordant for obesity.
|
Am J Cardiol
|
2012
|
0.82
|
|
128
|
Chlamydial lipopolysaccharide is present in serum during acute coronary syndrome and correlates with CRP levels.
|
Atherosclerosis
|
2006
|
0.81
|
|
129
|
Association of heart failure hospitalizations with combined electrocardiography and echocardiography criteria for left ventricular hypertrophy.
|
Am J Hypertens
|
2012
|
0.81
|
|
130
|
The association of serum neutrophil markers and acute coronary syndrome.
|
Scand J Immunol
|
2012
|
0.81
|
|
131
|
Association of hemoglobin delivery with left ventricular structure and function in hypertensive patients: Losartan Intervention for End Point Reduction in Hypertension Study.
|
Hypertension
|
2006
|
0.81
|
|
132
|
Relation of QT interval and QT dispersion to regression of echocardiographic and electrocardiographic left ventricular hypertrophy in hypertensive patients: the Losartan Intervention For Endpoint Reduction (LIFE) study.
|
Am Heart J
|
2003
|
0.81
|
|
133
|
A meta-analysis of genome-wide association studies of the electrocardiographic early repolarization pattern.
|
Heart Rhythm
|
2012
|
0.81
|
|
134
|
Two founder mutations in the alpha-tropomyosin and the cardiac myosin-binding protein C genes are common causes of hypertrophic cardiomyopathy in the Finnish population.
|
Ann Med
|
2012
|
0.81
|
|
135
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