Thomas Werfel

Author PubWeight™ 109.62‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Histamine down-regulates IL-27 production in antigen-presenting cells. J Leukoc Biol 2012 3.12
2 Standardizing double-blind, placebo-controlled oral food challenges: American Academy of Allergy, Asthma & Immunology-European Academy of Allergy and Clinical Immunology PRACTALL consensus report. J Allergy Clin Immunol 2012 2.90
3 Allergen-induced asthmatic responses modified by a GATA3-specific DNAzyme. N Engl J Med 2015 2.44
4 Age related, structured educational programmes for the management of atopic dermatitis in children and adolescents: multicentre, randomised controlled trial. BMJ 2006 2.41
5 Diagnosis and treatment of atopic dermatitis in children and adults: European Academy of Allergology and Clinical Immunology/American Academy of Allergy, Asthma and Immunology/PRACTALL Consensus Report. J Allergy Clin Immunol 2006 2.00
6 Human inflammatory dendritic epidermal cells express a functional histamine H4 receptor. J Invest Dermatol 2008 1.73
7 A comparison of oral methylprednisolone plus azathioprine or mycophenolate mofetil for the treatment of bullous pemphigoid. Arch Dermatol 2007 1.59
8 Histamine upregulates keratinocyte MMP-9 production via the histamine H1 receptor. J Invest Dermatol 2008 1.58
9 Human keratinocytes express AIM2 and respond to dsDNA with IL-1β secretion. Exp Dermatol 2011 1.53
10 The toll-like receptor 2 R753Q polymorphism defines a subgroup of patients with atopic dermatitis having severe phenotype. J Allergy Clin Immunol 2004 1.35
11 Correlation of IL-31 serum levels with severity of atopic dermatitis. J Allergy Clin Immunol 2008 1.28
12 Histamine H4 receptor stimulation suppresses IL-12p70 production and mediates chemotaxis in human monocyte-derived dendritic cells. J Immunol 2005 1.27
13 High-density genotyping study identifies four new susceptibility loci for atopic dermatitis. Nat Genet 2013 1.11
14 Investigation of contact allergy to dental metals in 206 patients. Contact Dermatitis 2009 1.10
15 Human keratinocytes respond to interleukin-18: implication for the course of chronic inflammatory skin diseases. J Invest Dermatol 2005 1.07
16 A comparison of oral methylprednisolone plus azathioprine or mycophenolate mofetil for the treatment of pemphigus. Arch Dermatol 2006 1.06
17 The Toll-like receptor 2 R753Q mutation modifies cytokine production and Toll-like receptor expression in atopic dermatitis. J Allergy Clin Immunol 2008 1.03
18 The histamine H4 receptor is functionally expressed on T(H)2 cells. J Allergy Clin Immunol 2009 1.01
19 IL-13-stimulated human keratinocytes preferentially attract CD4+CCR4+ T cells: possible role in atopic dermatitis. J Invest Dermatol 2006 1.00
20 Histamine H4 receptor antagonism reduces hapten-induced scratching behaviour but not inflammation. Exp Dermatol 2008 0.99
21 Malassezia sympodialis thioredoxin-specific T cells are highly cross-reactive to human thioredoxin in atopic dermatitis. J Allergy Clin Immunol 2011 0.98
22 Research needs in allergy: an EAACI position paper, in collaboration with EFA. Clin Transl Allergy 2012 0.97
23 Linking allergy to autoimmune disease. Trends Immunol 2009 0.97
24 Histamine downregulates monocyte CCL2 production through the histamine H4 receptor. J Allergy Clin Immunol 2007 0.96
25 Staphylococcal alpha-toxin is a strong inducer of interleukin-17 in humans. Infect Immun 2011 0.94
26 Modulation of keratinocyte-derived MMP-9 by IL-13: a possible role for the pathogenesis of epidermal inflammation. J Invest Dermatol 2007 0.93
27 Epicutaneous allergen administration: a novel approach for allergen-specific immunotherapy? J Allergy Clin Immunol 2009 0.93
28 Human plasmacytoid dendritic cells express receptors for anaphylatoxins C3a and C5a and are chemoattracted to C3a and C5a. J Invest Dermatol 2006 0.91
29 Structured education program improves the coping with atopic dermatitis in children and their parents-a multicenter, randomized controlled trial. J Psychosom Res 2009 0.91
30 Human monocyte-derived dendritic cells are chemoattracted to C3a after up-regulation of the C3a receptor with interferons. Immunology 2004 0.91
31 Staphylococcal exotoxins are strong inducers of IL-22: A potential role in atopic dermatitis. J Allergy Clin Immunol 2010 0.91
32 Evidence for a pathogenetic role of interleukin-18 in cutaneous lupus erythematosus. Arthritis Rheum 2008 0.90
33 Cooking birch pollen-related food: divergent consequences for IgE- and T cell-mediated reactivity in vitro and in vivo. J Allergy Clin Immunol 2006 0.90
34 Rapid identification and differentiation of fungal DNA in dermatological specimens by LightCycler PCR. J Med Microbiol 2004 0.89
35 Safety and efficacy of topical calcineurin inhibitors in the treatment of childhood atopic dermatitis. Am J Clin Dermatol 2005 0.89
36 Evidence for a regulatory loop between IFN-γ and IL-33 in skin inflammation. Exp Dermatol 2013 0.89
37 Does allergen-specific immunotherapy represent a therapeutic option for patients with atopic dermatitis? J Allergy Clin Immunol 2006 0.89
38 Efficacy and safety of subcutaneous allergen-specific immunotherapy with depigmented polymerized mite extract in atopic dermatitis. J Allergy Clin Immunol 2012 0.88
39 Long-term control of atopic dermatitis with pimecrolimus cream 1% in infants and young children: a two-year study. J Am Acad Dermatol 2005 0.88
40 RAC1 in keratinocytes regulates crosstalk to immune cells by Arp2/3-dependent control of STAT1. J Cell Sci 2012 0.88
41 Staphylococcus aureus-derived enterotoxins enhance house dust mite-induced patch test reactions in atopic dermatitis. Exp Dermatol 2007 0.88
42 Antibiotic treatment of cutaneous infections with Staphylococcus aureus in patients with atopic dermatitis: current antimicrobial resistances and susceptibilities. Exp Dermatol 2008 0.88
43 Suppression of IL-12 production by soluble CD40 ligand: evidence for involvement of the p44/42 mitogen-activated protein kinase pathway. J Immunol 2002 0.88
44 Role of macrophages in the pathogenesis of atopic dermatitis. Mediators Inflamm 2013 0.88
45 The histamine H4 receptor is highly expressed on plasmacytoid dendritic cells in psoriasis and histamine regulates their cytokine production and migration. J Invest Dermatol 2011 0.87
46 IL-27 Regulates IL-18 binding protein in skin resident cells. PLoS One 2012 0.87
47 A protective role of complement component 3 in T cell-mediated skin inflammation. Exp Dermatol 2011 0.87
48 Skin testing with food allergens. Guideline of the German Society of Allergology and Clinical Immunology (DGAKI), the Physicians' Association of German Allergologists (ADA) and the Society of Pediatric Allergology (GPA) together with the Swiss Society of Allergology. J Dtsch Dermatol Ges 2008 0.87
49 Pharmacological characterization of the new histamine H4 receptor agonist VUF 8430. Br J Pharmacol 2009 0.87
50 Expression and function of histamine receptors 1 and 2 on human monocyte-derived dendritic cells. J Allergy Clin Immunol 2002 0.87
51 [Atopic dermatitis: S2 guidelines]. J Dtsch Dermatol Ges 2009 0.86
52 Innate immunity, allergy and atopic dermatitis. Curr Opin Allergy Clin Immunol 2010 0.86
53 Primary human keratinocytes efficiently induce IL-1-dependent IL-17 in CCR6+ T cells. Exp Dermatol 2010 0.86
54 Human dendritic cells express the IL-18R and are chemoattracted to IL-18. J Immunol 2003 0.86
55 Allergy prevention. Dtsch Arztebl Int 2009 0.85
56 Staphylococcal α-toxin induces a higher T cell proliferation and interleukin-31 in atopic dermatitis. Int Arch Allergy Immunol 2011 0.85
57 Human memory Th17 cells express a functional histamine H4 receptor. Am J Pathol 2011 0.84
58 Diagnostic approach for suspected pseudoallergic reaction to food ingredients. J Dtsch Dermatol Ges 2008 0.84
59 Up-regulation of C5a receptor expression and function on human monocyte derived dendritic cells by prostaglandin E2. Immunology 2003 0.84
60 Difficult to control atopic dermatitis. World Allergy Organ J 2013 0.84
61 Pathogenetic and therapeutic implications of the histamine H4 receptor in inflammatory skin diseases and pruritus. Front Biosci (Schol Ed) 2011 0.83
62 IL-27 is expressed in chronic human eczematous skin lesions and stimulates human keratinocytes. J Allergy Clin Immunol 2009 0.83
63 Cyclosporine therapy in dermatology. J Dtsch Dermatol Ges 2009 0.83
64 Therapy of moderate and severe psoriasis. GMS Health Technol Assess 2006 0.83
65 Intracutaneous injection of the macrophage-activating lipopeptide-2 (MALP-2) which accelerates wound healing in mice--a phase I trial in 12 patients. Exp Dermatol 2008 0.82
66 Anxiety, depression and impaired health-related quality of life in patients with occupational hand eczema. Contact Dermatitis 2012 0.82
67 Perioral dermatitis. J Dtsch Dermatol Ges 2010 0.82
68 Proceedings of the 4th Georg Rajka International Symposium on Atopic Dermatitis, Arcachon, France, September 15-17, 2005. J Allergy Clin Immunol 2006 0.82
69 The diagnosis of food allergy: protocol for a systematic review. Clin Transl Allergy 2013 0.82
70 Influence of pimecrolimus cream 1% on different morphological signs of eczema in infants with atopic dermatitis. Dermatology 2004 0.81
71 A randomized, double-blind, vehicle-controlled study of 1% pimecrolimus cream in adult patients with perioral dermatitis. J Am Acad Dermatol 2008 0.81
72 Staphylococcus aureus fibronectin-binding protein specifically binds IgE from patients with atopic dermatitis and requires antigen presentation for cellular immune responses. J Allergy Clin Immunol 2011 0.81
73 Itch intensity evaluated in the German Atopic Dermatitis Intervention Study (GADIS): correlations with quality of life, coping behaviour and SCORAD severity in 823 children. Acta Derm Venereol 2008 0.81
74 [In vitro allergy diagnosis. Guideline of the German Society of Asthma and Immunology in conjunction with the German Society of Dermatology]. J Dtsch Dermatol Ges 2006 0.81
75 Induction of C3 and CCL2 by C3a in keratinocytes: a novel autocrine amplification loop of inflammatory skin reactions. J Immunol 2006 0.81
76 Human primary keratinocytes show restricted ability to up-regulate suppressor of cytokine signaling (SOCS)3 protein compared with autologous macrophages. J Biol Chem 2012 0.80
77 Allergy prevention. J Dtsch Dermatol Ges 2009 0.80
78 Histamine H(4) receptor activation on human slan-dendritic cells down-regulates their pro-inflammatory capacity. Immunology 2010 0.80
79 Allergic manifestations of skin diseases--atopic dermatitis. Chem Immunol Allergy 2006 0.80
80 Intrinsic alterations of pro-inflammatory mediators in unstimulated and TLR-2 stimulated keratinocytes from atopic dermatitis patients. Exp Dermatol 2011 0.80
81 IL-27 acts as a priming signal for IL-23 but not IL-12 production on human antigen-presenting cells. Exp Dermatol 2012 0.80
82 TLR-2-mediated cytokine and chemokine secretion in human keratinocytes. Exp Dermatol 2010 0.80
83 IMAGES IN CLINICAL MEDICINE. Bullous Pemphigoid. N Engl J Med 2015 0.80
84 The human skin-associated autoantigen α-NAC activates monocytes and dendritic cells via TLR-2 and primes an IL-12-dependent Th1 response. J Invest Dermatol 2013 0.79
85 Subcutaneous immunotherapy with a depigmented polymerized birch pollen extract--a new therapeutic option for patients with atopic dermatitis. Int Arch Allergy Immunol 2011 0.79
86 The role of the histamine H4 receptor in atopic dermatitis. Curr Allergy Asthma Rep 2011 0.79
87 Food allergy and atopic dermatitis: how are they connected? Curr Allergy Asthma Rep 2011 0.79
88 Osteopontin in the development of systemic sclerosis--relation to disease activity and organ manifestation. Rheumatology (Oxford) 2010 0.79
89 Histamine downregulates the Th1-associated chemokine IP-10 in monocytes and myeloid dendritic cells. Int Arch Allergy Immunol 2013 0.79
90 Histamine induces proliferation in keratinocytes from patients with atopic dermatitis through the histamine 4 receptor. J Allergy Clin Immunol 2013 0.79
91 Participation of complement 3a receptor (C3aR) in the sensitization phase of Th2 mediated allergic contact dermatitis. Exp Dermatol 2012 0.78
92 Well characterized antihistamine 4 receptor antibodies contribute to current knowledge of the expression and biology of the human and murine histamine 4 receptor. Naunyn Schmiedebergs Arch Pharmacol 2012 0.78
93 Dysregulation of CD36 upon TLR-2 stimulation in monocytes from patients with atopic dermatitis and the TLR2 R753Q polymorphism. Exp Dermatol 2010 0.78
94 Polymorphisms within the C3 gene are associated with specific IgE levels to common allergens and super-antigens among atopic dermatitis patients. Exp Dermatol 2008 0.78
95 Critical involvement of IL-12 in IFN-gamma induction by calcineurin antagonists in activated human lymphocytes. J Leukoc Biol 2006 0.77
96 The epidemiology of food allergy in Europe: protocol for a systematic review. Clin Transl Allergy 2013 0.77
97 Expression of antimicrobial peptides in atopic dermatitis and possible immunoregulatory functions. Curr Opin Allergy Clin Immunol 2013 0.77
98 Regulation of IL-13 receptors in human keratinocytes. J Invest Dermatol 2007 0.77
99 Is European legislation killing allergy diagnostics? Curr Opin Allergy Clin Immunol 2012 0.77
100 Cell-to-cell contact between activated CD4+ T lymphocytes and unprimed monocytes interferes with a TH1 response. J Allergy Clin Immunol 2004 0.77
101 Development of drug delivery systems for the dermal application of therapeutic DNAzymes. Int J Pharm 2012 0.77
102 Interaction of keratinocytes with infiltrating lymphocytes in allergic eczematous skin diseases. Curr Opin Allergy Clin Immunol 2006 0.77
103 The acute and long-term management of food allergy: protocol for a rapid systematic review. Clin Transl Allergy 2013 0.77
104 Resting but not CpG stimulated keratinocytes suppress autologous T-helper cell proliferation--importance of PGE2 and T regulatory function. Exp Dermatol 2011 0.76
105 Comparison of localized high-dose UVA1 irradiation versus topical cream psoralen-UVA for treatment of chronic vesicular dyshidrotic eczema. J Am Acad Dermatol 2004 0.76
106 The histamine H4 receptor regulates chemokine production in human natural killer cells. Int Arch Allergy Immunol 2015 0.76
107 Staphylococcal α-toxin induces a functional upregulation of TLR-2 on human peripheral blood monocytes. Exp Dermatol 2015 0.76
108 Predictors of benefit from an atopic dermatitis education programme. Pediatr Allergy Immunol 2014 0.76
109 The suppressive role of IL-10 in contact and atopic dermatitis. J Allergy Clin Immunol 2012 0.76
110 Stringent elimination diet. Dtsch Arztebl Int 2009 0.75
111 Staphylococcal exotoxins induce interleukin 22 in human th22 cells. Int Arch Allergy Immunol 2014 0.75
112 Reply: To PMID 23195525. J Allergy Clin Immunol 2013 0.75
113 Alterations of stress-induced expression of membrane molecules and intracellular cytokine levels in patients with atopic dermatitis depend on serum IgE levels. J Allergy Clin Immunol 2004 0.75
114 Correction required. Dtsch Arztebl Int 2010 0.75
115 [IgG food allergies - a subject of controversy]. Dtsch Med Wochenschr 2011 0.75
116 Contact reactions to food. Curr Allergy Asthma Rep 2008 0.75
117 Psoriasis predisposition and occupational triggering factors in the appraisal of occupational medical expertises. J Dtsch Dermatol Ges 2014 0.75
118 Keratinocytes enriched for epidermal stem cells differ in their response to IFN-gamma from other proliferative keratinocytes. Exp Dermatol 2008 0.75
119 Human keratinocytes release high levels of inducible heat shock protein 70 that enhances peptide uptake. Exp Dermatol 2011 0.75
120 [Neurodermatitis]. Hautarzt 2006 0.75
121 Psoriasis predisposition and occupational triggering factors in the appraisal of occupational medical expertises. J Dtsch Dermatol Ges 2014 0.75
122 Atopic eczema and food allergy. Chem Immunol Allergy 2015 0.75
123 [In Process Citation]. J Dtsch Dermatol Ges 2015 0.75
124 Addition of pimecrolimus cream 1% to a topical corticosteroid treatment regimen in paediatric patients with severe atopic dermatitis: a randomized, double-blind trial. J Dermatolog Treat 2010 0.75
125 [Therapy of atopic eczema with calcineurin inhibitors]. J Dtsch Dermatol Ges 2005 0.75
126 The functional activity of basophil granulocytes is modulated by acute mental stress and sympathetic activation in vivo and in vitro. J Allergy Clin Immunol 2008 0.75
127 Occupational allergic contact dermatitis to cresyl glycidyl ether (CGE). Eur J Dermatol 2007 0.75
128 [The Working Group on Allergology in the DDG]. J Dtsch Dermatol Ges 2014 0.75
129 Skin allergy. Curr Opin Allergy Clin Immunol 2017 0.75
130 Quantitative repeated open application testing with a rinse-off product in methyldibromo glutaronitrile-sensitive patients: results of the IVDK. Contact Dermatitis 2010 0.75
131 Successful therapy of annular elastolytic giant cell granuloma with fumaric acid esters. Dermatology 2002 0.75