Published in J Immunol on April 01, 2006
The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease. Clin Exp Immunol (2007) 3.51
Drug-induced autoimmune-like hepatitis. Dig Dis Sci (2011) 2.86
PD1 blockade reverses the suppression of melanoma antigen-specific CTL by CD4+ CD25(Hi) regulatory T cells. Int Immunol (2009) 2.10
Rabbit ATG but not horse ATG promotes expansion of functional CD4+CD25highFOXP3+ regulatory T cells in vitro. Blood (2008) 1.95
Notch1 and TGFbeta1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells. Blood (2008) 1.69
Deficient CD4+ CD25+ FOXP3+ T regulatory cells in acquired aplastic anemia. Blood (2007) 1.44
Ectopic expression of neural autoantigen in mouse liver suppresses experimental autoimmune neuroinflammation by inducing antigen-specific Tregs. J Clin Invest (2008) 1.44
Autoimmune Hepatitis: Progress from Global Immunosuppression to Personalised Regulatory T Cell Therapy. Can J Gastroenterol Hepatol (2016) 1.39
Translational mini-review series on Th17 cells: induction of interleukin-17 production by regulatory T cells. Clin Exp Immunol (2009) 1.37
Higher intratumoral infiltrated Foxp3+ Treg numbers and Foxp3+/CD8+ ratio are associated with adverse prognosis in resectable gastric cancer. J Cancer Res Clin Oncol (2010) 1.34
Interleukin-17 contributes to the pathogenesis of autoimmune hepatitis through inducing hepatic interleukin-6 expression. PLoS One (2011) 1.27
Localisation pattern of Foxp3+ regulatory T cells is associated with clinical behaviour in gastric cancer. Br J Cancer (2007) 1.26
T regulatory cell levels decrease in people infected with Schistosoma mansoni on effective treatment. Am J Trop Med Hyg (2007) 1.14
Deficiency in regulatory T cells results in development of antimitochondrial antibodies and autoimmune cholangitis. Hepatology (2009) 1.14
Regulatory T cells and human disease. Clin Dev Immunol (2007) 1.12
Aetiopathogenesis of autoimmune hepatitis. World J Gastroenterol (2008) 1.11
Low numbers of regulatory T cells in common variable immunodeficiency: association with chronic inflammation in vivo. Clin Exp Immunol (2007) 1.08
Regulatory T cells in human autoimmune diseases. Springer Semin Immunopathol (2006) 1.07
Autoimmune hepatitis: new paradigms in the pathogenesis, diagnosis, and management. Hepatol Int (2010) 1.05
Autoantibody-negative autoimmune hepatitis. Dig Dis Sci (2011) 1.03
Regulatory T cells differentially modulate the maturation and apoptosis of human CD8+ T-cell subsets. Blood (2009) 0.98
Update on autoimmune hepatitis. World J Gastroenterol (2009) 0.98
Analysis of regulatory T cells and IgG4-positive plasma cells among patients of IgG4-related sclerosing cholangitis and autoimmune liver diseases. J Gastroenterol (2010) 0.96
Suppressive efficacy and proliferative capacity of human regulatory T cells in allogeneic and xenogeneic responses. Transplantation (2008) 0.95
Tolerance to melanin-associated antigen in autoimmune uveitis is mediated by CD4+CD25+ T-regulatory cells. Am J Pathol (2008) 0.90
Update on Autoimmune Hepatitis. J Clin Transl Hepatol (2015) 0.89
Advances in the current treatment of autoimmune hepatitis. Dig Dis Sci (2012) 0.89
Mechanisms of tissue injury in autoimmune liver diseases. Semin Immunopathol (2014) 0.89
Autoimmune hepatitis. Semin Immunopathol (2009) 0.88
Tumor-Infiltrating Immune Cells Are Associated With Prognosis of Gastric Cancer. Medicine (Baltimore) (2015) 0.86
The liver works as a school to educate regulatory immune cells. Cell Mol Immunol (2013) 0.86
Modulation of liver tolerance by conventional and nonconventional antigen-presenting cells and regulatory immune cells. Cell Mol Immunol (2016) 0.85
Exploring the Role of Killer Cell Immunoglobulin-Like Receptors and Their HLA Class I Ligands in Autoimmune Hepatitis. PLoS One (2016) 0.84
Genetic background of autoimmune hepatitis in Japan. J Gastroenterol (2010) 0.84
Rituximab for the treatment of patients with autoimmune hepatitis who are refractory or intolerant to standard therapy. Can J Gastroenterol (2013) 0.83
Autoimmune Hepatitis: Clinical Review with Insights into the Purinergic Mechanism of Disease. J Clin Transl Hepatol (2013) 0.83
The interaction between regulatory T cells and NKT cells in the liver: a CD1d bridge links innate and adaptive immunity. PLoS One (2011) 0.83
Autoimmune hepatitis in children: experiences in a tertiary center. Iran J Pediatr (2013) 0.83
Cell mediators of autoimmune hepatitis and their therapeutic implications. Dig Dis Sci (2014) 0.82
Use of cannabinoids as a novel therapeutic modality against autoimmune hepatitis. Vitam Horm (2009) 0.81
Epstein-barr virus as a trigger of autoimmune liver diseases. Adv Virol (2012) 0.81
Regulatory T Cells in Autoimmune and Viral Chronic Hepatitis. J Immunol Res (2015) 0.81
Short report: Childhood coinfections with Plasmodium falciparum and Schistosoma mansoni result in lower percentages of activated T cells and T regulatory memory cells than schistosomiasis only. Am J Trop Med Hyg (2009) 0.81
Autoimmune hepatitis, one disease with many faces: etiopathogenetic, clinico-laboratory and histological characteristics. World J Gastroenterol (2015) 0.81
Xenobiotic exposure and autoimmune hepatitis. Hepat Res Treat (2010) 0.80
CD8⁺ Treg cells associated with decreasing disease activity after intravenous methylprednisolone pulse therapy in lupus nephritis with heavy proteinuria. PLoS One (2014) 0.80
Regulatory T cells, especially ICOS(+) FOXP3(+) regulatory T cells, are increased in the hepatocellular carcinoma microenvironment and predict reduced survival. Sci Rep (2016) 0.79
Management of patients with difficult autoimmune hepatitis. Therap Adv Gastroenterol (2012) 0.79
Hepatitis mouse models: from acute-to-chronic autoimmune hepatitis. Int J Exp Pathol (2014) 0.79
T helper 17 cells in autoimmune liver diseases. Clin Dev Immunol (2013) 0.79
Harnessing regulatory T cells for the treatment of inflammatory bowel disease. Inflamm Bowel Dis (2015) 0.79
Autoimmune hepatitis as a unique form of an autoimmune liver disease: immunological aspects and clinical overview. Autoimmune Dis (2012) 0.79
Emerging opportunities for site-specific molecular and cellular interventions in autoimmune hepatitis. Dig Dis Sci (2010) 0.78
Chemokine and chemokine receptors in autoimmunity: the case of primary biliary cholangitis. Expert Rev Clin Immunol (2016) 0.78
The role of vitamin d in autoimmune hepatitis. J Clin Med Res (2013) 0.78
Adaptive immunity in the liver. Cell Mol Immunol (2016) 0.78
Autoimmune hepatitis and primary sclerosing cholangitis in children and adolescents. Fetal Pediatr Pathol (2014) 0.78
Dietary n-3 PUFA Protects Mice from Con A Induced Liver Injury by Modulating Regulatory T Cells and PPAR-γ Expression. PLoS One (2015) 0.78
Late relapse of type 1 autoimmune hepatitis after corticosteroid withdrawal. Dig Dis Sci (2010) 0.77
Diagnosis and Management of Autoimmune Hepatitis: Current Status and Future Directions. Gut Liver (2016) 0.77
The Role of Regulatory CD4 T Cells in Maintaining Tolerance in a Mouse Model of Autoimmune Hepatitis. PLoS One (2015) 0.77
Therapeutic Potential of IL-17-Mediated Signaling Pathway in Autoimmune Liver Diseases. Mediators Inflamm (2015) 0.76
CD8 blockade promotes the expansion of antigen-specific CD4+ FOXP3+ regulatory T cells in vivo. Int Immunopharmacol (2006) 0.76
Autoimmune hepatitis in childhood: the role of genetic and immune factors. World J Gastroenterol (2013) 0.76
Effects of low-dose-gamma rays on the immune system of different animal models of disease. Dose Response (2014) 0.75
Interleukin-21 plays a critical role in the pathogenesis and severity of type I autoimmune hepatitis. Springerplus (2016) 0.75
Novel Immunotherapies for Autoimmune Hepatitis. Front Pediatr (2017) 0.75
Low-dose interleukin-2 promotes STAT-5 phosphorylation, Treg survival and CTLA-4-dependent function in autoimmune liver diseases. Clin Exp Immunol (2017) 0.75
Chinese medicine bu xu hua yu recipe for the regulation of treg/th17 ratio imbalance in autoimmune hepatitis. Evid Based Complement Alternat Med (2015) 0.75
Relationship between serum adenosine deaminase levels and liver histology in autoimmune hepatitis. World J Gastroenterol (2017) 0.75
The induction of autoimmune hepatitis in the human leucocyte antigen-DR4 non-obese diabetic mice autoimmune hepatitis mouse model. Clin Exp Immunol (2016) 0.75
Regulatory and activated effector T cells in chronic hepatitis C virus: Relation to autoimmunity. World J Hepatol (2016) 0.75
Immunosuppressive drugs affect interferon (IFN)-γ and programmed cell death 1 (PD-1) kinetics in patients with newly diagnosed autoimmune hepatitis. Clin Exp Immunol (2017) 0.75
Regulatory T Cell and Forkhead Box Protein 3 as Modulators of Immune Homeostasis. Front Immunol (2017) 0.75
Two-dimensional nanosheets produced by liquid exfoliation of layered materials. Science (2011) 6.00
Diagnosis and management of autoimmune hepatitis. Hepatology (2010) 5.27
Evaluation of risk factors in the development of hepatocellular carcinoma in autoimmune hepatitis: Implications for follow-up and screening. Hepatology (2008) 2.98
Source and characterization of hepatic macrophages in acetaminophen-induced acute liver failure in humans. Hepatology (2012) 2.81
Stimulation of host bone marrow stromal cells by sympathetic nerves promotes breast cancer bone metastasis in mice. PLoS Biol (2012) 2.58
A map of human cancer signaling. Mol Syst Biol (2007) 2.50
Dysfunctional CD39(POS) regulatory T cells and aberrant control of T-helper type 17 cells in autoimmune hepatitis. Hepatology (2014) 2.29
Safety and efficacy of N-acetylcysteine in children with non-acetaminophen-induced acute liver failure. Liver Transpl (2008) 1.97
Severe bile salt export pump deficiency: 82 different ABCB11 mutations in 109 families. Gastroenterology (2008) 1.95
Three immunomarker support vector machines-based prognostic classifiers for stage IB non-small-cell lung cancer. J Clin Oncol (2009) 1.91
Missense mutations and single nucleotide polymorphisms in ABCB11 impair bile salt export pump processing and function or disrupt pre-messenger RNA splicing. Hepatology (2009) 1.90
Antenatal presentation of biliary atresia. J Pediatr (2004) 1.82
Hepatocellular carcinoma in ten children under five years of age with bile salt export pump deficiency. Hepatology (2006) 1.80
Antibodies to conformational epitopes of soluble liver antigen define a severe form of autoimmune liver disease. Hepatology (2002) 1.77
Randomized, double-blind, placebo-controlled trial of corticosteroids after Kasai portoenterostomy for biliary atresia. Hepatology (2007) 1.76
Long-term survival following Kasai portoenterostomy: is chronic liver disease inevitable? J Pediatr Gastroenterol Nutr (2003) 1.75
Cytochrome P450IID6-specific CD8 T cell immune responses mirror disease activity in autoimmune hepatitis type 2. Hepatology (2007) 1.68
C-terminal deletions in the ALAS2 gene lead to gain of function and cause X-linked dominant protoporphyria without anemia or iron overload. Am J Hum Genet (2008) 1.64
Serotonin transporter promoter variant: Analysis in Indian IBS patients and control population. J Clin Gastroenterol (2009) 1.64
Does cross-reactivity between mycobacterium avium paratuberculosis and human intestinal antigens characterize Crohn's disease? Gastroenterology (2006) 1.64
One liver, three recipients: segment IV from split-liver procedures as a source of hepatocytes for cell transplantation. Transplantation (2004) 1.62
Mycophenolate mofetil as rescue treatment for autoimmune liver disease in children: a 5-year follow-up. J Hepatol (2009) 1.61
Serial circulating markers of inflammation in biliary atresia--evolution of the post-operative inflammatory process. Hepatology (2007) 1.61
Differences in presentation and progression between severe FIC1 and BSEP deficiencies. J Hepatol (2010) 1.60
Neonatal hemochromatosis--medical treatment vs. transplantation: the king's experience. Liver Transpl (2005) 1.60
The human bile salt export pump: characterization of substrate specificity and identification of inhibitors. Gastroenterology (2002) 1.58
Liver transplantation for propionic acidemia in children. Liver Transpl (2011) 1.56
Impairment of CD4(+)CD25(+) regulatory T-cells in autoimmune liver disease. J Hepatol (2004) 1.54
A genetic study of Wilson's disease in the United Kingdom. Brain (2013) 1.53
Human hepatocyte transplantation: current experience and future challenges. Nat Rev Gastroenterol Hepatol (2010) 1.52
Autoantigen-specific regulatory T cells, a potential tool for immune-tolerance reconstitution in type-2 autoimmune hepatitis. Hepatology (2010) 1.51
Character and temporal evolution of apoptosis in acetaminophen-induced acute liver failure*. Crit Care Med (2013) 1.51
The importance of immune dysfunction in determining outcome in acute liver failure. J Hepatol (2008) 1.50
Aetiology and management of extrahepatic portal vein obstruction in children: King's College Hospital experience. J Pediatr Gastroenterol Nutr (2008) 1.48
Alcohol dehydrogenase-specific T-cell responses are associated with alcohol consumption in patients with alcohol-related cirrhosis. Hepatology (2013) 1.47
Cystatin C, an easy and reliable marker for assessment of renal dysfunction in children with liver disease and after liver transplantation. Liver Transpl (2005) 1.47
Serum hepatocyte growth factor and vascular endothelial growth factor in children with acute liver failure. J Pediatr Gastroenterol Nutr (2007) 1.47
A clinical prediction rule and platelet count predict esophageal varices in children. Gastroenterology (2011) 1.44
Re-evaluation of the penicillamine challenge test in the diagnosis of Wilson's disease in children. J Hepatol (2007) 1.44
Chronic liver disease related to 6-thioguanine in children with acute lymphoblastic leukaemia. J Hepatol (2005) 1.44
Diaphragmatic dysfunction after pediatric orthotopic liver transplantation. Transplantation (2002) 1.43
The biliary atresia splenic malformation syndrome: a 28-year single-center retrospective study. J Pediatr (2006) 1.42
Interferon alfa-2b in combination with ribavirin for the treatment of chronic hepatitis C in children: efficacy, safety, and pharmacokinetics. Hepatology (2005) 1.40
Image of the month. Copper-metallothionein autofluorescence. Hepatology (2009) 1.39
Immunohistochemical phenotyping of the inflammatory infiltrate in de novo autoimmune hepatitis after liver transplantation in children. Pediatr Transplant (2012) 1.38
Autoimmune hepatitis. J Hepatol (2010) 1.38
Acute sickle cell hepatopathy represents a potential contraindication for percutaneous liver biopsy. Blood (2002) 1.34
Autoimmune liver serology: current diagnostic and clinical challenges. World J Gastroenterol (2008) 1.34
Tunable stress and controlled thickness modification in graphene by annealing. ACS Nano (2008) 1.33
Improving the techniques for human hepatocyte transplantation: report from a consensus meeting in London. Cell Transplant (2012) 1.31
Reduced monocyte HLA-DR expression: a novel biomarker of disease severity and outcome in acetaminophen-induced acute liver failure. Hepatology (2006) 1.30
Current status of hepatocyte transplantation. Transplantation (2012) 1.28
Antibodies against homologous microbial caseinolytic proteases P characterise primary biliary cirrhosis. J Hepatol (2002) 1.24
Hepatocyte transplantation for inherited factor VII deficiency. Transplantation (2004) 1.18
Hepatocyte transplantation for liver-based metabolic disorders. J Inherit Metab Dis (2006) 1.17
Autoimmune hepatitis: a comprehensive review. J Autoimmun (2012) 1.16
The significance of autoantibodies and immunoglobulins in acute liver failure: a cohort study. J Hepatol (2007) 1.16
The increasing prevalence of hepatitis delta virus (HDV) infection in South London. J Med Virol (2008) 1.15
Autoimmune hepatitis. Nat Rev Gastroenterol Hepatol (2011) 1.14
Wilson's disease in children: 37-year experience and revised King's score for liver transplantation. Liver Transpl (2005) 1.13
PBC screen: an IgG/IgA dual isotype ELISA detecting multiple mitochondrial and nuclear autoantibodies specific for primary biliary cirrhosis. J Autoimmun (2010) 1.13
Serum levels of CK18 M30 and leptin are useful predictors of steatohepatitis and fibrosis in paediatric NAFLD. J Pediatr Gastroenterol Nutr (2010) 1.13
Effect of CD4+ CD25+ regulatory T-cells on CD8 T-cell function in patients with autoimmune hepatitis. J Autoimmun (2005) 1.13
Intratumoral FOXP3 expression in infiltrating breast carcinoma: Its association with clinicopathologic parameters and angiogenesis. Acta Oncol (2007) 1.13
Variable clinical spectrum of the most common inborn error of bile acid metabolism--3beta-hydroxy-Delta 5-C27-steroid dehydrogenase deficiency. J Pediatr Gastroenterol Nutr (2010) 1.12
Aetiopathogenesis of autoimmune hepatitis. World J Gastroenterol (2008) 1.11
The polymorphisms of GSTM1, GSTT1, HYL1*2, and XRCC1, and aflatoxin B1-related hepatocellular carcinoma in Guangxi population, China. Hepatol Res (2006) 1.10
A multifaceted imbalance of T cells with regulatory function characterizes type 1 autoimmune hepatitis. Hepatology (2010) 1.10