Cell-cell communication beyond connexins: the pannexin channels.

Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor. EMBO J (2006) 8.12

The role of pannexin 1 hemichannels in ATP release and cell-cell communication in mouse taste buds. Proc Natl Acad Sci U S A (2007) 4.01

Connexin channel permeability to cytoplasmic molecules. Prog Biophys Mol Biol (2007) 2.73

Pharmacological characterization of pannexin-1 currents expressed in mammalian cells. J Pharmacol Exp Ther (2008) 2.42

ATP release through connexin hemichannels and gap junction transfer of second messengers propagate Ca2+ signals across the inner ear. Proc Natl Acad Sci U S A (2008) 2.01

ATP release from non-excitable cells. Purinergic Signal (2009) 1.78

Discovery of P2X7 receptor-selective antagonists offers new insights into P2X7 receptor function and indicates a role in chronic pain states. Br J Pharmacol (2007) 1.77

Lens gap junctions in growth, differentiation, and homeostasis. Physiol Rev (2010) 1.70

Pannexin 1 channels mediate the release of ATP into the lumen of the rat urinary bladder. J Physiol (2015) 1.59

Pannexins in ischemia-induced neurodegeneration. Proc Natl Acad Sci U S A (2011) 1.55

Gap junction channels exhibit connexin-specific permeability to cyclic nucleotides. J Gen Physiol (2008) 1.35

Modulation of brain hemichannels and gap junction channels by pro-inflammatory agents and their possible role in neurodegeneration. Antioxid Redox Signal (2009) 1.34

Intercellular Ca(2+) waves: mechanisms and function. Physiol Rev (2012) 1.32

The P2X(7) receptor-pannexin connection to dye uptake and IL-1beta release. Purinergic Signal (2009) 1.32

From mechanosensitivity to inflammatory responses: new players in the pathology of glaucoma. Curr Eye Res (2013) 1.31

Pannexin 3 functions as an ER Ca(2+) channel, hemichannel, and gap junction to promote osteoblast differentiation. J Cell Biol (2011) 1.29

Voltage dependence of ATP secretion in mammalian taste cells. J Gen Physiol (2008) 1.19

Glial connexins and gap junctions in CNS inflammation and disease. J Neurochem (2008) 1.17

Gap junctions couple astrocytes and oligodendrocytes. J Mol Neurosci (2008) 1.16

High resolution map of Caenorhabditis elegans gap junction proteins. Dev Dyn (2009) 1.14

Molecular disruptions of the panglial syncytium block potassium siphoning and axonal saltatory conduction: pertinence to neuromyelitis optica and other demyelinating diseases of the central nervous system. Neuroscience (2009) 1.13

A new look at electrolyte transport in the distal tubule. Annu Rev Physiol (2011) 1.13

Connexins and pannexins: Coordinating cellular communication in the testis and epididymis. Spermatogenesis (2011) 1.13

Mefloquine blockade of Pannexin1 currents: resolution of a conflict. Cell Commun Adhes (2009) 1.12

Identification and characterization of pannexin expression in the mammalian cochlea. J Comp Neurol (2009) 1.10

Genetic ablation of Pannexin1 protects retinal neurons from ischemic injury. PLoS One (2012) 1.10

Structural and functional similarities of calcium homeostasis modulator 1 (CALHM1) ion channel with connexins, pannexins, and innexins. J Biol Chem (2013) 1.10

Gap junctions and hemichannels in signal transmission, function and development of bone. Biochim Biophys Acta (2011) 1.08

Direct observation of ATP-induced conformational changes in single P2X(4) receptors. PLoS Biol (2009) 1.06

Both sides now: multiple interactions of ATP with pannexin-1 hemichannels. Focus on "A permeant regulating its permeation pore: inhibition of pannexin 1 channels by ATP". Am J Physiol Cell Physiol (2009) 1.06

Expression and roles of pannexins in ATP release in the pituitary gland. Endocrinology (2011) 1.04

Pannexin1 and pannexin3 delivery, cell surface dynamics, and cytoskeletal interactions. J Biol Chem (2010) 1.03

Posttranslational modifications in connexins and pannexins. J Membr Biol (2012) 1.00

Intrarenal localization of the plasma membrane ATP channel pannexin1. Am J Physiol Renal Physiol (2012) 0.99

P2Y2 receptor activation opens pannexin-1 channels in rat carotid body type II cells: potential role in amplifying the neurotransmitter ATP. J Physiol (2012) 0.98

What is hidden in the pannexin treasure trove: the sneak peek and the guesswork. J Cell Mol Med (2006) 0.98

ATP released from cardiac fibroblasts via connexin hemichannels activates profibrotic P2Y2 receptors. FASEB J (2012) 0.98

P2 receptor-mediated signaling in mast cell biology. Purinergic Signal (2009) 0.98

Promises and pitfalls of a Pannexin1 transgenic mouse line. Front Pharmacol (2013) 0.97

Expression of pannexin isoforms in the systemic murine arterial network. J Vasc Res (2012) 0.95

Neuroglial ATP release through innexin channels controls microglial cell movement to a nerve injury. J Gen Physiol (2010) 0.95

Is pannexin the pore associated with the P2X7 receptor? Naunyn Schmiedebergs Arch Pharmacol (2013) 0.95

Interactions of connexins with other membrane channels and transporters. Prog Biophys Mol Biol (2007) 0.93

Nature of plasmalemmal functional "hemichannels". Biochim Biophys Acta (2011) 0.93

Contribution of pannexin1 to experimental autoimmune encephalomyelitis. PLoS One (2013) 0.91

Gap junctions and hemichannels composed of connexins: potential therapeutic targets for neurodegenerative diseases. Front Cell Neurosci (2014) 0.91

Testicular connexin 43, a precocious molecular target for the effect of environmental toxicants on male fertility. Spermatogenesis (2011) 0.90

Possible involvement of different connexin43 domains in plasma membrane permeabilization induced by ischemia-reperfusion. J Membr Biol (2007) 0.90

Gap junctions in the ovary of Drosophila melanogaster: localization of innexins 1, 2, 3 and 4 and evidence for intercellular communication via innexin-2 containing channels. BMC Dev Biol (2008) 0.90

Characterization of nonjunctional hemichannels in caterpillar cells. J Insect Sci (2011) 0.90

Pannexin 2 protein expression is not restricted to the CNS. Front Cell Neurosci (2014) 0.89

Pannexin protein expression in the rat middle cerebral artery. J Vasc Res (2012) 0.89

Large-conductance channel formation mediated by P2X7 receptor activation is regulated through distinct intracellular signaling pathways in peritoneal macrophages and 2BH4 cells. Naunyn Schmiedebergs Arch Pharmacol (2010) 0.89

How do taste cells lacking synapses mediate neurotransmission? CALHM1, a voltage-gated ATP channel. Bioessays (2013) 0.86

Characterization of novel Pannexin 1 isoforms from rat pituitary cells and their association with ATP-gated P2X channels. Gen Comp Endocrinol (2011) 0.86

Angiotensin II mobilizes intracellular calcium and activates pannexin-1 channels in rat carotid body type II cells via AT1 receptors. J Physiol (2014) 0.85

Ryanodine receptors selectively contribute to the formation of taste-evoked calcium signals in mouse taste cells. Eur J Neurosci (2010) 0.85

Revisiting the stimulus-secretion coupling in the adrenal medulla: role of gap junction-mediated intercellular communication. Mol Neurobiol (2009) 0.84

Role of Pannexin-1 hemichannels and purinergic receptors in the pathogenesis of human diseases. Front Physiol (2014) 0.83

Amplification of human platelet activation by surface pannexin-1 channels. J Thromb Haemost (2014) 0.83

CNQX and AMPA inhibit electrical synaptic transmission: a potential interaction between electrical and glutamatergic synapses. Brain Res (2008) 0.81

Inactivation and Anion Selectivity of Volume-regulated Anion Channels (VRACs) Depend on C-terminal Residues of the First Extracellular Loop. J Biol Chem (2016) 0.81

Bioelectric patterning during oogenesis: stage-specific distribution of membrane potentials, intracellular pH and ion-transport mechanisms in Drosophila ovarian follicles. BMC Dev Biol (2015) 0.79

Patterns of heterogeneous expression of pannexin 1 and pannexin 2 transcripts in the olfactory epithelium and olfactory bulb. J Mol Histol (2012) 0.79

Pannexin1-mediated ATP release provides signal transmission between Neuro2A cells. Neurochem Res (2012) 0.79

Assessing a potential role of host Pannexin 1 during Chlamydia trachomatis infection. PLoS One (2013) 0.78

Structural order in Pannexin 1 cytoplasmic domains. Channels (Austin) (2014) 0.78

Probenecid as a sensitizer of bisphosphonate-mediated effects in breast cancer cells. Mol Cancer (2014) 0.77

Recognition and control of the progression of age-related hearing loss. Rejuvenation Res (2013) 0.76

Pannexin 3 and connexin 43 modulate skeletal development through their distinct functions and expression patterns. J Cell Sci (2016) 0.76

Pannexin-1 and P2X7-Receptor Are Required for Apoptotic Osteocytes in Fatigued Bone to Trigger RANKL Production in Neighboring Bystander Osteocytes. J Bone Miner Res (2016) 0.76

Pore positioning: current concepts in Pannexin channel trafficking. Channels (Austin) (2013) 0.76

Interactions of Pannexin1 channels with purinergic and NMDA receptor channels. Biochim Biophys Acta (2017) 0.75

Pannexin channels mediate the acquisition of myogenic commitment in C2C12 reserve cells promoted by P2 receptor activation. Front Cell Dev Biol (2015) 0.75

Connexins, Pannexins, and Their Channels in Fibroproliferative Diseases. J Membr Biol (2016) 0.75

Pannexin1 Channels Are Required for Chemokine-Mediated Migration of CD4+ T Lymphocytes: Role in Inflammation and Experimental Autoimmune Encephalomyelitis. J Immunol (2016) 0.75

Loss of Panx1 Impairs Mammary Gland Development at Lactation: Implications for Breast Tumorigenesis. PLoS One (2016) 0.75

The double life of connexin channels: single is a treat. J Invest Dermatol (2015) 0.75

Role of connexins and pannexins during ontogeny, regeneration, and pathologies of bone. BMC Cell Biol (2016) 0.75

Expression and function of pannexins in the inner ear and hearing. BMC Cell Biol (2016) 0.75

Large Pore Ion and Metabolite-Permeable Channel Regulation of Postnatal Ventricular Zone Neural Stem and Progenitor Cells: Interplay between Aquaporins, Connexins, and Pannexins? Stem Cells Int (2012) 0.75

Pannexins, a family of gap junction proteins expressed in brain. Proc Natl Acad Sci U S A (2003) 3.96

Pharmacological properties of homomeric and heteromeric pannexin hemichannels expressed in Xenopus oocytes. J Neurochem (2005) 3.87

Recruitment of parvalbumin-positive interneurons determines hippocampal function and associated behavior. Neuron (2007) 3.67

CKAMP44: a brain-specific protein attenuating short-term synaptic plasticity in the dentate gyrus. Science (2010) 3.17

Fast synaptic inhibition promotes synchronized gamma oscillations in hippocampal interneuron networks. Proc Natl Acad Sci U S A (2002) 2.92

New insights into the classification and nomenclature of cortical GABAergic interneurons. Nat Rev Neurosci (2013) 2.65

In vivo labeling of parvalbumin-positive interneurons and analysis of electrical coupling in identified neurons. J Neurosci (2002) 2.38

Targeted whole-cell recordings in the mammalian brain in vivo. Neuron (2003) 2.35

Hippocampal theta rhythm and its coupling with gamma oscillations require fast inhibition onto parvalbumin-positive interneurons. Proc Natl Acad Sci U S A (2009) 2.34

Connexin36 mediates spike synchrony in olfactory bulb glomeruli. Neuron (2005) 2.26

NMDA receptor ablation on parvalbumin-positive interneurons impairs hippocampal synchrony, spatial representations, and working memory. Neuron (2010) 2.21

High-frequency network oscillations in cerebellar cortex. Neuron (2008) 2.12

Functional characterization of intrinsic cholinergic interneurons in the cortex. J Neurosci (2007) 2.08

A novel network of multipolar bursting interneurons generates theta frequency oscillations in neocortex. Neuron (2003) 2.05

ATP release through connexin hemichannels and gap junction transfer of second messengers propagate Ca2+ signals across the inner ear. Proc Natl Acad Sci U S A (2008) 2.01

Differential involvement of oriens/pyramidale interneurones in hippocampal network oscillations in vitro. J Physiol (2004) 2.00

Parvalbumin-containing fast-spiking basket cells generate the field potential oscillations induced by cholinergic receptor activation in the hippocampus. J Neurosci (2010) 1.93

Ca2+ buffer saturation underlies paired pulse facilitation in calbindin-D28k-containing terminals. Neuron (2003) 1.88

A role for fast rhythmic bursting neurons in cortical gamma oscillations in vitro. Proc Natl Acad Sci U S A (2004) 1.80

GABAergic interneurons shape the functional maturation of the cortex. Neuron (2013) 1.79

Neurogenesis and widespread forebrain migration of distinct GABAergic neurons from the postnatal subventricular zone. Proc Natl Acad Sci U S A (2008) 1.78

Contribution of hippocampal and extra-hippocampal NR2B-containing NMDA receptors to performance on spatial learning tasks. Neuron (2008) 1.78

Orthogonal arrangement of rhythm-generating microcircuits in the hippocampus. Proc Natl Acad Sci U S A (2005) 1.71

Tumor-suppressive effects of pannexin 1 in C6 glioma cells. Cancer Res (2007) 1.70

Role of olivary electrical coupling in cerebellar motor learning. Neuron (2008) 1.67

Pannexin1 and Pannexin2 expression in the developing and mature rat brain. Brain Res Mol Brain Res (2005) 1.67

Connexin-dependent inter-cellular communication increases invasion and dissemination of Shigella in epithelial cells. Nat Cell Biol (2003) 1.66

Long-range-projecting GABAergic neurons modulate inhibition in hippocampus and entorhinal cortex. Science (2012) 1.58

Pannexins in ischemia-induced neurodegeneration. Proc Natl Acad Sci U S A (2011) 1.55

Specific gene transfer to neurons, endothelial cells and hematopoietic progenitors with lentiviral vectors. Nat Methods (2010) 1.48

Open source clinical science for emerging infections. Lancet Infect Dis (2014) 1.47

The integrity of cholinergic basal forebrain neurons depends on expression of Nkx2-1. Eur J Neurosci (2011) 1.46

Excitotoxicity in vitro by NR2A- and NR2B-containing NMDA receptors. Neuropharmacology (2007) 1.44

Contrasting roles of axonal (pyramidal cell) and dendritic (interneuron) electrical coupling in the generation of neuronal network oscillations. Proc Natl Acad Sci U S A (2003) 1.38

Serotonin 3A receptor subtype as an early and protracted marker of cortical interneuron subpopulations. Cereb Cortex (2010) 1.33

Electrical synapses: a dynamic signaling system that shapes the activity of neuronal networks. Biochim Biophys Acta (2004) 1.31

GABAergic excitation in the basolateral amygdala. J Neurosci (2006) 1.30

A molecular basis of analgesic tolerance to cannabinoids. J Neurosci (2007) 1.28

Two calretinin-positive GABAergic cell types in layer 2/3 of the mouse neocortex provide different forms of inhibition. Cereb Cortex (2008) 1.28

Connexin36 mediates gap junctional coupling of alpha-ganglion cells in mouse retina. J Comp Neurol (2005) 1.26

Connexin30 mutations responsible for hidrotic ectodermal dysplasia cause abnormal hemichannel activity. Hum Mol Genet (2004) 1.23

Effects of electrically coupled inhibitory networks on local neuronal responses to intracortical microstimulation. J Neurophysiol (2006) 1.22

The N-terminal region of reelin regulates postnatal dendritic maturation of cortical pyramidal neurons. Proc Natl Acad Sci U S A (2009) 1.22

Expression of connexin36 in cone pedicles and OFF-cone bipolar cells of the mouse retina. J Neurosci (2004) 1.18

Bergmann glial AMPA receptors are required for fine motor coordination. Science (2012) 1.18

Transient depression of excitatory synapses on interneurons contributes to epileptiform bursts during gamma oscillations in the mouse hippocampal slice. J Neurophysiol (2005) 1.18

Diazepam binding inhibitor promotes progenitor proliferation in the postnatal SVZ by reducing GABA signaling. Cell Stem Cell (2012) 1.17

Sharp wave-like activity in the hippocampus in vitro in mice lacking the gap junction protein connexin 36. J Neurophysiol (2003) 1.16

Features of neuronal synchrony in mouse visual cortex. J Neurophysiol (2003) 1.16

Pathogenetic role of the deafness-related M34T mutation of Cx26. Hum Mol Genet (2006) 1.14

Regulation of body temperature and neuroprotection by endogenous interleukin-6 in cerebral ischemia. J Cereb Blood Flow Metab (2003) 1.13

Efficient assembly and secretion of recombinant subviral particles of the four dengue serotypes using native prM and E proteins. PLoS One (2009) 1.13

Two variants of the rat brain sodium-driven chloride bicarbonate exchanger (NCBE): developmental expression and addition of a PDZ motif. Eur J Neurosci (2003) 1.10

Virtual cloning, functional expression, and gating analysis of human connexin31.9. Am J Physiol Cell Physiol (2002) 1.10

Hearing loss: frequency and functional studies of the most common connexin26 alleles. Biochem Biophys Res Commun (2002) 1.09

The long and short of GABAergic neurons. Curr Opin Neurobiol (2013) 1.09

H5-type influenza virus hemagglutinin is functionally recognized by the natural killer-activating receptor NKp44. J Virol (2007) 1.08

Hemichannels in cerebral ischemia. Curr Mol Med (2009) 1.07

Gene expression analysis of in vivo fluorescent cells. PLoS One (2007) 1.06

Increased subventricular zone-derived cortical neurogenesis after ischemic lesion. Exp Neurol (2010) 1.05

Cell coupling and Cx43 expression in embryonic mouse neural progenitor cells. J Cell Sci (2002) 1.05

Cleavage of the SARS coronavirus spike glycoprotein by airway proteases enhances virus entry into human bronchial epithelial cells in vitro. PLoS One (2009) 1.05

Analysis of the effects of cannabinoids on identified synaptic connections in the caudate-putamen by paired recordings in transgenic mice. J Physiol (2006) 1.04

Modulation of perch connexin35 hemi-channels by cyclic AMP requires a protein kinase A phosphorylation site. J Neurosci Res (2003) 1.04

Class II ADP-ribosylation factors are required for efficient secretion of dengue viruses. J Biol Chem (2011) 1.02

The SARS coronavirus E protein interacts with PALS1 and alters tight junction formation and epithelial morphogenesis. Mol Biol Cell (2010) 1.01

Input-output features of anatomically identified CA3 neurons during hippocampal sharp wave/ripple oscillation in vitro. J Neurosci (2013) 1.00

Functional outcome of pannexin-deficient mice after cerebral ischemia. Channels (Austin) (2012) 0.99

The role of electrical signaling via gap junctions in the generation of fast network oscillations. Brain Res Bull (2003) 0.99

A BCR-JAK2 fusion gene as the result of a t(9;22)(p24;q11) in a patient with acute myeloid leukemia. Cancer Genet Cytogenet (2008) 0.99

Thyroid hormone is required for hypothalamic neurons regulating cardiovascular functions. J Clin Invest (2012) 0.98

A reporter allele for investigating connexin 26 gene expression in the mouse brain. Eur J Neurosci (2003) 0.96

Mice with genetically altered glutamate receptors as models of schizophrenia: a comprehensive review. Neurosci Biobehav Rev (2009) 0.94

Major signaling pathways in migrating neuroblasts. Front Mol Neurosci (2009) 0.94

Molecular diversity of neocortical GABAergic interneurones. J Physiol (2004) 0.93

EphA4 preserves postnatal and adult neural stem cells in an undifferentiated state in vivo. J Cell Sci (2011) 0.93

Augmented hippocampal ripple oscillations in mice with reduced fast excitation onto parvalbumin-positive cells. J Neurosci (2009) 0.93

Anti-severe acute respiratory syndrome coronavirus spike antibodies trigger infection of human immune cells via a pH- and cysteine protease-independent FcγR pathway. J Virol (2011) 0.93

Gap junctions between interneurons are required for normal spatial coding in the hippocampus and short-term spatial memory. J Neurosci (2011) 0.92

Endocannabinoid-mediated long-term depression of afferent excitatory synapses in hippocampal pyramidal cells and GABAergic interneurons. J Neurosci (2012) 0.92

Molecular cloning and functional expression of zfCx52.6: a novel connexin with hemichannel-forming properties expressed in horizontal cells of the zebrafish retina. J Biol Chem (2003) 0.91

In vivo evidence for the involvement of the carboxy terminal domain in assembling connexin 36 at the electrical synapse. Mol Cell Neurosci (2010) 0.90

Expression of Pannexin1 in the outer plexiform layer of the mouse retina and physiological impact of its knockout. J Comp Neurol (2013) 0.89

A single residue substitution in the receptor-binding domain of H5N1 hemagglutinin is critical for packaging into pseudotyped lentiviral particles. PLoS One (2012) 0.89

A versatile system for the neuronal subtype specific expression of lentiviral vectors. FASEB J (2009) 0.89

Ezrin interacts with the SARS coronavirus Spike protein and restrains infection at the entry stage. PLoS One (2012) 0.88

"Small axonless neurons": postnatally generated neocortical interneurons with delayed functional maturation. J Neurosci (2011) 0.88

Somato-dendritic nicotinic receptor responses recorded in vitro from the medial septal diagonal band complex of the rodent. J Physiol (2004) 0.87

5-HT(3A) receptor-bearing white matter interstitial GABAergic interneurons are functionally integrated into cortical and subcortical networks. J Neurosci (2011) 0.87

Connexins, innexins and pannexins: bridging the communication gap. Biochim Biophys Acta (2005) 0.86

Selective defects in channel permeability associated with Cx32 mutations causing X-linked Charcot-Marie-Tooth disease. Neurobiol Dis (2006) 0.85

Subventricular zone-derived neuroblasts use vasculature as a scaffold to migrate radially to the cortex in neonatal mice. Cereb Cortex (2011) 0.85

Connective tissue growth factor regulates interneuron survival and information processing in the olfactory bulb. Neuron (2013) 0.85

HMGA2 overexpression in polycythemia vera with t(12;21)(q14;q22). Cancer Genet Cytogenet (2007) 0.85

GluN2B-containing NMDA receptors promote wiring of adult-born neurons into olfactory bulb circuits. J Neurosci (2012) 0.84

Masked Philadelphia chromosome due to atypical BCR/ABL localization on the 9q34 band and duplication of the der(9) in a case of chronic myelogenous leukemia. Cancer Genet Cytogenet (2005) 0.84

Synaptic NR2A- but not NR2B-Containing NMDA Receptors Increase with Blockade of Ionotropic Glutamate Receptors. Front Mol Neurosci (2009) 0.83

Signaling involved in neurite outgrowth of postnatally born subventricular zone neurons in vitro. BMC Neurosci (2010) 0.83