PubRank

Leonie K Ashman

Author PubWeight™ 30.93‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Juxtamembrane mutant V560GKit is more sensitive to Imatinib (STI571) compared with wild-type c-kit whereas the kinase domain mutant D816VKit is resistant. Mol Cancer Ther 2002 2.68
2 Essential requirement for PP2A inhibition by the oncogenic receptor c-KIT suggests PP2A reactivation as a strategy to treat c-KIT+ cancers. Cancer Res 2010 2.06
3 Characterization of mice lacking the tetraspanin superfamily member CD151. Mol Cell Biol 2004 1.57
4 alpha3beta1 integrin-CD151, a component of the cadherin-catenin complex, regulates PTPmu expression and cell-cell adhesion. J Cell Biol 2003 1.49
5 A critical role for tetraspanin CD151 in alpha3beta1 and alpha6beta4 integrin-dependent tumor cell functions on laminin-5. Mol Biol Cell 2006 1.47
6 Deletion of CD151 results in a strain-dependent glomerular disease due to severe alterations of the glomerular basement membrane. Am J Pathol 2008 1.36
7 Colocalization of the tetraspanins, CO-029 and CD151, with integrins in human pancreatic adenocarcinoma: impact on cell motility. Clin Cancer Res 2005 1.27
8 Wound healing is defective in mice lacking tetraspanin CD151. J Invest Dermatol 2006 1.22
9 CD151 protein expression predicts the clinical outcome of low-grade primary prostate cancer better than histologic grading: a new prognostic indicator? Cancer Epidemiol Biomarkers Prev 2004 1.19
10 The tetraspanin superfamily member CD151 regulates outside-in integrin alphaIIbbeta3 signaling and platelet function. Blood 2004 1.14
11 Overexpression of P-glycoprotein in K562 cells does not confer resistance to the growth inhibitory effects of imatinib (STI571) in vitro. Blood 2003 1.06
12 Resistance to c-KIT kinase inhibitors conferred by V654A mutation. Mol Cancer Ther 2007 1.03
13 Src family kinases are involved in the differential signaling from two splice forms of c-Kit. J Biol Chem 2003 1.02
14 An in vivo tumor model exploiting metabolic response as a biomarker for targeted drug development. Cancer Res 2005 1.02
15 Identification of Tspan9 as a novel platelet tetraspanin and the collagen receptor GPVI as a component of tetraspanin microdomains. Biochem J 2009 1.00
16 Constitutively active mutant D816VKit induces megakayocyte and mast cell differentiation of early haemopoietic cells from murine foetal liver. Leuk Res 2003 0.90
17 The role of the tetraspanin CD151 in primary keratinocyte and fibroblast functions: implications for wound healing. Exp Cell Res 2008 0.89
18 Physical proximity and functional interplay of PECAM-1 with the Fc receptor Fc gamma RIIa on the platelet plasma membrane. Blood 2003 0.89
19 The migration and invasion of human prostate cancer cell lines involves CD151 expression. Oncol Rep 2010 0.86
20 Genetic ablation of the tetraspanin CD151 reduces spontaneous metastatic spread of prostate cancer in the TRAMP model. Mol Cancer Res 2012 0.85
21 Probing the interaction of tetraspanin CD151 with integrin alpha 3 beta 1 using a panel of monoclonal antibodies with distinct reactivities toward the CD151-integrin alpha 3 beta 1 complex. Biochem J 2008 0.82
22 Evidence for the involvement of PECAM-1 in a receptor mediated signal-transduction pathway regulating capacitation-associated tyrosine phosphorylation in human spermatozoa. J Cell Sci 2005 0.82
23 Colony stimulating factor-1 receptor as a target for small molecule inhibitors. Bioorg Med Chem 2010 0.81
24 Early myeloid cells expressing c-KIT isoforms differ in signal transduction, survival and chemotactic responses to Stem Cell Factor. Cell Signal 2007 0.80
25 Knockout of the tetraspanin Cd9 in the TRAMP model of de novo prostate cancer increases spontaneous metastases in an organ-specific manner. Int J Cancer 2013 0.78
26 KIT gene mutations in gastrointestinal stromal tumors: more complex than previously recognized? Am J Pathol 2002 0.76
27 Deletion of Cd151 reduces mammary tumorigenesis in the MMTV/PyMT mouse model. BMC Cancer 2014 0.76
28 Role of c-KIT expression level and phosphatidylinositol 3-kinase activation in survival and proliferative responses of early myeloid cells. Cell Signal 2005 0.75
29 Expression of biologically active human colony stimulating factor-1 in Pichia pastoris. Protein Expr Purif 2012 0.75