Published in Am J Hum Genet on March 17, 2006
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nat Genet (2007) 12.62
What can genome-wide association studies tell us about the genetics of common disease? PLoS Genet (2008) 2.35
Rapid and accurate multiple testing correction and power estimation for millions of correlated markers. PLoS Genet (2009) 2.30
Genome-wide association studies and beyond. Annu Rev Public Health (2010) 1.73
Power analysis for genome-wide association studies. BMC Genet (2007) 1.72
Evaluating cost efficiency of SNP chips in genome-wide association studies. Genet Epidemiol (2008) 1.60
Mathematical properties of the r2 measure of linkage disequilibrium. Theor Popul Biol (2008) 1.51
Identification of new SLE-associated genes with a two-step Bayesian study design. Genes Immun (2009) 1.07
Imputation-based genomic coverage assessments of current human genotyping arrays. G3 (Bethesda) (2013) 1.06
Methodological Issues in Multistage Genome-wide Association Studies. Stat Sci (2009) 1.06
Efficient association study design via power-optimized tag SNP selection. Ann Hum Genet (2008) 1.01
Information capture using SNPs from HapMap and whole-genome chips differs in a sample of inflammatory and cardiovascular gene-centric regions from genome-wide estimates. Genome Res (2007) 0.96
The impact of improved microarray coverage and larger sample sizes on future genome-wide association studies. Genet Epidemiol (2013) 0.94
FTO influences on longitudinal BMI over childhood and adulthood and modulation on relationship between birth weight and longitudinal BMI. Hum Genet (2010) 0.92
New tools for functional genomic analysis. Drug Discov Today (2009) 0.84
One thousand genomes imputation in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium aggressive prostate cancer genome-wide association study. Prostate (2012) 0.83
Windfalls and pitfalls: Applications of population genetics to the search for disease genes. Evol Med Public Health (2013) 0.78
Genome-wide association studies and cancer. Hawaii Med J (2010) 0.75
Influences of FTO gene on onset age of adult overweight. Hum Genet (2012) 0.75
Genetic contributors to variation in alcohol consumption vary by race/ethnicity in a large multi-ethnic genome-wide association study. Mol Psychiatry (2017) 0.75
A haplotype map of the human genome. Nature (2005) 105.70
The ENCODE (ENCyclopedia Of DNA Elements) Project. Science (2004) 38.24
Whole-genome patterns of common DNA variation in three human populations. Science (2005) 21.22
Linkage disequilibrium in humans: models and data. Am J Hum Genet (2001) 14.97
Variation is the spice of life. Nat Genet (2001) 7.62
Sample size requirements for association studies of gene-gene interaction. Am J Epidemiol (2002) 6.09
The relative power of family-based and case-control designs for linkage disequilibrium studies of complex human diseases I. DNA pooling. Genome Res (1998) 5.11
Haplotype diversity across 100 candidate genes for inflammation, lipid metabolism, and blood pressure regulation in two populations. Am J Hum Genet (2004) 3.91
The impact of SNP density on fine-scale patterns of linkage disequilibrium. Hum Mol Genet (2004) 2.78
Assessing the performance of the haplotype block model of linkage disequilibrium. Am J Hum Genet (2003) 2.59
Ethnicity and human genetic linkage maps. Am J Hum Genet (2004) 1.50
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet (2013) 8.02
Point: population stratification: a problem for case-control studies of candidate-gene associations? Cancer Epidemiol Biomarkers Prev (2002) 6.00
RNASEL Arg462Gln variant is implicated in up to 13% of prostate cancer cases. Nat Genet (2002) 3.87
Genetic dissection of complex traits with chromosome substitution strains of mice. Science (2004) 3.57
The landscape of recombination in African Americans. Nature (2011) 3.06
Comprehensive approach to analyzing rare genetic variants. PLoS One (2010) 2.93
The Scientific Foundation for personal genomics: recommendations from a National Institutes of Health-Centers for Disease Control and Prevention multidisciplinary workshop. Genet Med (2009) 2.91
Multiple prostate cancer risk variants on 8q24. Nat Genet (2007) 2.76
Genome-wide association study of prostate cancer in men of African ancestry identifies a susceptibility locus at 17q21. Nat Genet (2011) 2.70
Enriching the analysis of genomewide association studies with hierarchical modeling. Am J Hum Genet (2007) 2.32
VALID: visualization of association study results and linkage disequilibrium. Genet Epidemiol (2009) 2.18
Hierarchical modeling of linkage disequilibrium: genetic structure and spatial relations. Am J Hum Genet (2003) 2.05
A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. Nat Genet (2013) 1.82
Using hierarchical modeling in genetic association studies with multiple markers: application to a case-control study of bladder cancer. Cancer Epidemiol Biomarkers Prev (2004) 1.72
A gene-centric approach to genome-wide association studies. Nat Rev Genet (2006) 1.72
8q24 and prostate cancer: association with advanced disease and meta-analysis. Eur J Hum Genet (2008) 1.72
Characterizing genetic risk at known prostate cancer susceptibility loci in African Americans. PLoS Genet (2011) 1.54
Nonsteroidal antiinflammatory drugs and decreased risk of advanced prostate cancer: modification by lymphotoxin alpha. Am J Epidemiol (2006) 1.53
Impact of meat consumption, preparation, and mutagens on aggressive prostate cancer. PLoS One (2011) 1.52
A genome-wide association study identifies novel loci for paclitaxel-induced sensory peripheral neuropathy in CALGB 40101. Clin Cancer Res (2012) 1.50
Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry. PLoS Genet (2011) 1.47
Next generation analytic tools for large scale genetic epidemiology studies of complex diseases. Genet Epidemiol (2011) 1.47
Podocalyxin variants and risk of prostate cancer and tumor aggressiveness. Hum Mol Genet (2006) 1.46
Toll-like receptor 4 genetic variation and advanced prostate cancer risk. Cancer Epidemiol Biomarkers Prev (2007) 1.45
Diacylglycerol kinase K variants impact hypospadias in a California study population. J Urol (2012) 1.43
Haplotype tagging single nucleotide polymorphisms and association studies. Hum Hered (2003) 1.29
Socioeconomic status and prostate cancer incidence and mortality rates among the diverse population of California. Cancer Causes Control (2009) 1.28
Dissecting effects of complex mixtures: who's afraid of informative priors? Epidemiology (2007) 1.21
The Covariate's Dilemma. PLoS Genet (2012) 1.19
DNA repair gene XRCC1 and XPD polymorphisms and risk of prostate cancer. Cancer Epidemiol Biomarkers Prev (2004) 1.19
Turning of COGS moves forward findings for hormonally mediated cancers. Nat Genet (2013) 1.18
Prostatitis, sexually transmitted diseases, and prostate cancer: the California Men's Health Study. PLoS One (2010) 1.16
A genome-wide association study (GWAS) for bronchopulmonary dysplasia. Pediatrics (2013) 1.15
Dietary omega-3 fatty acids, cyclooxygenase-2 genetic variation, and aggressive prostate cancer risk. Clin Cancer Res (2009) 1.13
Prostate cancer aggressiveness locus on chromosome 7q32-q33 identified by linkage and allelic imbalance studies. Neoplasia (2002) 1.11
Role of androgen metabolism genes CYP1B1, PSA/KLK3, and CYP11alpha in prostate cancer risk and aggressiveness. Cancer Epidemiol Biomarkers Prev (2005) 1.09
Relation of serum insulin-like growth factor-I (IGF-I) and IGF binding protein-3 to risk of prostate cancer (United States). Cancer Causes Control (2003) 1.07
Carboxypeptidase 4 gene variants and early-onset intermediate-to-high risk prostate cancer. BMC Cancer (2009) 1.07
Increased power for case-control studies of single nucleotide polymorphisms through incorporation of family history and genetic constraints. Genet Epidemiol (2004) 1.06
Prostate cancer susceptibility variants confer increased risk of disease progression. Cancer Epidemiol Biomarkers Prev (2010) 1.06
Androgen receptor CAG repeats and prostate cancer. Am J Epidemiol (2002) 1.05
The association between a Darc gene polymorphism and clinical outcomes in African American patients with acute lung injury. Chest (2011) 1.02
Association of the innate immunity and inflammation pathway with advanced prostate cancer risk. PLoS One (2012) 1.01
Polymorphisms in polycyclic aromatic hydrocarbon metabolism and conjugation genes, interactions with smoking and prostate cancer risk. Cancer Epidemiol Biomarkers Prev (2006) 0.99
Association of prostate cancer risk and aggressiveness to androgen pathway genes: SRD5A2, CYP17, and the AR. Prostate (2004) 0.98
Copy number alterations in prostate tumors and disease aggressiveness. Genes Chromosomes Cancer (2011) 0.97
A genetic signature of spina bifida risk from pathway-informed comprehensive gene-variant analysis. PLoS One (2011) 0.96
Generalizability of established prostate cancer risk variants in men of African ancestry. Int J Cancer (2014) 0.96
CYP3A4 and CYP3A5 genotypes, haplotypes, and risk of prostate cancer. Cancer Epidemiol Biomarkers Prev (2003) 0.96
Novel missense mutations of the Deleted-in-AZoospermia-Like (DAZL) gene in infertile women and men. Reprod Biol Endocrinol (2006) 0.95
The impact of improved microarray coverage and larger sample sizes on future genome-wide association studies. Genet Epidemiol (2013) 0.94
Co-regulatory expression quantitative trait loci mapping: method and application to endometrial cancer. BMC Med Genomics (2011) 0.94
Polymorphisms in estrogen bioactivation, detoxification and oxidative DNA base excision repair genes and prostate cancer risk. Carcinogenesis (2006) 0.94
Hierarchical modeling identifies novel lung cancer susceptibility variants in inflammation pathways among 10,140 cases and 11,012 controls. Hum Genet (2013) 0.93
Acute lung injury and the coagulation pathway: Potential role of gene polymorphisms in the protein C and fibrinolytic pathways. Intensive Care Med (2006) 0.92
Impact of consumption of vegetable, fruit, grain, and high glycemic index foods on aggressive prostate cancer risk. Nutr Cancer (2011) 0.92
Vitamin D receptor genotypes/haplotypes and prostate cancer risk. Cancer Epidemiol Biomarkers Prev (2006) 0.92
Variants in Deleted in AZoospermia-Like (DAZL) are correlated with reproductive parameters in men and women. Hum Genet (2005) 0.91
No association between genetic polymorphisms in IGF-I and IGFBP-3 and prostate cancer. Cancer Epidemiol Biomarkers Prev (2004) 0.89
Hierarchical modeling in association studies of multiple phenotypes. BMC Genet (2005) 0.89
Genetic Analysis Workshop 15: gene expression analysis and approaches to detecting multiple functional loci. BMC Proc (2007) 0.89
Comprehensive evaluation of the association between prostate cancer and genotypes/haplotypes in CYP17A1, CYP3A4, and SRD5A2. Eur J Hum Genet (2004) 0.89
Nutrient pathways and neural tube defects: a semi-Bayesian hierarchical analysis. Epidemiology (2009) 0.88
Omega-3 fatty acids, genetic variants in COX-2 and prostate cancer. J Nutrigenet Nutrigenomics (2009) 0.88
Prostate cancer aggressiveness locus on chromosome segment 19q12-q13.1 identified by linkage and allelic imbalance studies. Genes Chromosomes Cancer (2003) 0.88
Hypospadias and genes related to genital tubercle and early urethral development. J Urol (2013) 0.85
MIC1 and IL1RN genetic variation and advanced prostate cancer risk. Cancer Epidemiol Biomarkers Prev (2007) 0.84
Genome-wide association studies of cancer. Future Oncol (2007) 0.84
Joint association testing of common and rare genetic variants using hierarchical modeling. Genet Epidemiol (2012) 0.84
Relationship between methylenetetrahydrofolate reductase C677T and A1298C genotypes and haplotypes and prostate cancer risk and aggressiveness. Cancer Epidemiol Biomarkers Prev (2004) 0.83
National Cancer Institute Prostate Cancer Genetics Workshop. Cancer Res (2011) 0.82
Antioxidant and vitamin E transport genes and risk of high-grade prostate cancer and prostate cancer recurrence. Prostate (2013) 0.82
Selenoprotein and antioxidant genes and the risk of high-grade prostate cancer and prostate cancer recurrence. Prostate (2014) 0.82
No association between genetic polymorphisms in insulin and insulin receptor substrate-1 and prostate cancer. Cancer Epidemiol Biomarkers Prev (2005) 0.81
Trans-fatty acid intake and increased risk of advanced prostate cancer: modification by RNASEL R462Q variant. Carcinogenesis (2007) 0.81
Does accounting for gene-environment interactions help uncover association between rare variants and complex diseases? Hum Hered (2013) 0.81
No association between a tetranucleotide repeat polymorphism of CYP19 and prostate cancer. Cancer Epidemiol Biomarkers Prev (2004) 0.80
Copy number variation in bronchopulmonary dysplasia. Am J Med Genet A (2014) 0.79
Comparison of missing data approaches in linkage analysis. BMC Genet (2003) 0.79
Plasminogen activator inhibitor type-1 (PAI-1) polymorphism 4G/5G is associated with prostate cancer among men with a positive family history. Prostate (2007) 0.79
Fine-mapping of prostate cancer aggressiveness loci on chromosome 7q22-35. Prostate (2010) 0.78
Impact of polymorphisms in drug pathway genes on disease-free survival in adults with acute myeloid leukemia. J Hum Genet (2013) 0.78
Maternal smoking, xenobiotic metabolizing enzyme gene variants, and gastroschisis risk. Am J Med Genet A (2014) 0.78
Population genetic simulations of complex phenotypes with implications for rare variant association tests. Genet Epidemiol (2014) 0.77
Relationship between body size and prostate cancer in a sibling based case-control study. J Urol (2005) 0.76
Analysis of mutational spectra: locating hotspots and clusters of mutations using recursive segmentation. Stat Med (2002) 0.76
Association of testis derived transcript gene variants and prostate cancer risk. J Urol (2007) 0.76
Segmentation and estimation for SNP microarrays: a Bayesian multiple change-point approach. Biometrics (2010) 0.75
An empirical evaluation of the common disease-common variant hypothesis. BMC Proc (2007) 0.75
Non-Steroidal Anti-Inflammatory Drugs, Variation in Inflammatory Genes, and Aggressive Prostate Cancer. Pharmaceuticals (Basel) (2010) 0.75
Host genetic predictors of the kynurenine pathway of tryptophan catabolism among treated HIV-infected Ugandans. AIDS (2016) 0.75
Current Challenges and New Opportunities for Gene-Environment Interaction Studies of Complex Diseases. Am J Epidemiol (2017) 0.75
Update on the State of the Science for Analytical Methods for Gene-Environment Interactions. Am J Epidemiol (2017) 0.75
Case-control analyses: Geneopardy! Genet Epidemiol (2005) 0.75
The role of genetic variation in Toll-like receptor 4 in prostate cancer susceptibility: a review. Expert Opin Med Diagn (2008) 0.75
Of models and methods. Cancer Epidemiol Biomarkers Prev (2011) 0.75
Parametric linkage analysis. Methods Mol Biol (2002) 0.75
Conference Scene: Lessons learned from the 5th Statistical Analysis Workshop of the Pharmacogenetics Research Network. Pharmacogenomics (2010) 0.75
Genome-wide association analyses of expression phenotypes. Genet Epidemiol (2007) 0.75