Published in Oncogene on May 01, 2006
CPEB regulation of human cellular senescence, energy metabolism, and p53 mRNA translation. Genes Dev (2008) 1.66
Upregulation of Nox4 in the aging vasculature and its association with smooth muscle cell polyploidy. Cell Cycle (2009) 1.63
p53 regulates a non-apoptotic death induced by ROS. Cell Death Differ (2013) 1.25
Regulation of Chk1 by its C-terminal domain. Mol Biol Cell (2008) 1.03
Cancer cell survival following DNA damage-mediated premature senescence is regulated by mammalian target of rapamycin (mTOR)-dependent Inhibition of sirtuin 1. J Biol Chem (2011) 1.00
Identification of potential therapeutic targets in malignant mesothelioma using cell-cycle gene expression analysis. Am J Pathol (2009) 0.96
Turning off the G2 DNA damage checkpoint. DNA Repair (Amst) (2007) 0.91
Cutting edge: Chk1 directs senescence and mitotic catastrophe in recovery from G₂ checkpoint arrest. J Cell Mol Med (2011) 0.89
The mismatch repair system modulates curcumin sensitivity through induction of DNA strand breaks and activation of G2-M checkpoint. Mol Cancer Ther (2010) 0.83
Sp1 is involved in H2O2-induced PUMA gene expression and apoptosis in colorectal cancer cells. J Exp Clin Cancer Res (2008) 0.78
Murine sarcoma and leukemia viruses: assay using clonal lines of contact-inhibited mouse cells. J Virol (1969) 11.78
In vitro cultivation of human tumors: establishment of cell lines derived from a series of solid tumors. J Natl Cancer Inst (1973) 11.26
Development of 3T3-like lines from Balb-c mouse embryo cultures: transformation susceptibility to SV40. J Cell Physiol (1968) 10.54
Simian sarcoma virus onc gene, v-sis, is derived from the gene (or genes) encoding a platelet-derived growth factor. Science (1983) 9.06
Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product. Science (1991) 8.68
A rapid in vitro assay for quantitating the invasive potential of tumor cells. Cancer Res (1987) 7.43
Induction of murine C-type viruses from clonal lines of virus-free BALB-3T3 cells. Science (1971) 6.71
Amplification of a novel v-erbB-related gene in a human mammary carcinoma. Science (1985) 6.56
erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells. Science (1987) 6.36
Expression of cellular homologues of retroviral onc genes in human hematopoietic cells. Proc Natl Acad Sci U S A (1982) 5.80
Overexpression of the human EGF receptor confers an EGF-dependent transformed phenotype to NIH 3T3 cells. Cell (1987) 5.11
Cellular genes analogous to retroviral onc genes are transcribed in human tumour cells. Nature (1982) 5.11
Purification and characterization of a newly identified growth factor specific for epithelial cells. Proc Natl Acad Sci U S A (1989) 5.10
Characterization of murine sarcoma virus (Kirsten) transformation of mouse and human cells. J Gen Virol (1971) 5.01
Human KGF is FGF-related with properties of a paracrine effector of epithelial cell growth. Science (1989) 4.79
T24 human bladder carcinoma oncogene is an activated form of the normal human homologue of BALB- and Harvey-MSV transforming genes. Nature (1982) 4.54
Determination of ligand-binding specificity by alternative splicing: two distinct growth factor receptors encoded by a single gene. Proc Natl Acad Sci U S A (1992) 4.50
Independent segregation of loci for activation of biologically distinguishable RNA C-type viruses in mouse cells. Proc Natl Acad Sci U S A (1973) 4.39
Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow. Nat Cell Biol (2001) 4.38
Differential expression of the amv gene in human hematopoietic cells. Proc Natl Acad Sci U S A (1982) 4.37
PDGF induction of tyrosine phosphorylation of GTPase activating protein. Nature (1989) 4.36
Acquisition of transforming properties by alternative point mutations within c-bas/has human proto-oncogene. Nature (1983) 4.34
Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasis. J Cell Biol (2000) 4.33
Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: evidence for overexpression in a subset of human mammary tumors. Proc Natl Acad Sci U S A (1989) 4.17
gag Gene of mammalian type-C RNA tumour viruses. Nature (1976) 4.11
Cooperative signaling of ErbB3 and ErbB2 in neoplastic transformation and human mammary carcinomas. Oncogene (1995) 4.10
Basis for the acquisition of malignant potential by mouse cells cultivated in vitro. Science (1968) 4.00
Accuracy of fecal occult blood screening for colorectal neoplasia. A prospective study using Hemoccult and HemoQuant tests. JAMA (1993) 3.91
Nonproducer clones of murine sarcoma virus transformed BALB-3T3 cells. Virology (1970) 3.85
Ultralong single-wall carbon nanotubes. Nat Mater (2004) 3.83
Separation of murine cellular and murine leukaemia virus DNA polymerases. Nat New Biol (1971) 3.71
Metabolism of vitamin D3-3H in human subjects: distribution in blood, bile, feces, and urine. J Clin Invest (1967) 3.69
Expression cDNA cloning of the KGF receptor by creation of a transforming autocrine loop. Science (1991) 3.69
Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbl oncogene product. Nature (1991) 3.68
Microsatellite instability and 8p allelic imbalance in stage B2 and C colorectal cancers. J Natl Cancer Inst (1999) 3.46
Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes. Cell Death Differ (2009) 3.44
Biochemical modulation of fluorouracil: evidence of significant improvement of survival and quality of life in patients with advanced colorectal carcinoma. J Clin Oncol (1989) 3.44
High-dose vitamin C versus placebo in the treatment of patients with advanced cancer who have had no prior chemotherapy. A randomized double-blind comparison. N Engl J Med (1985) 3.36
Microsatellite instability in colorectal cancer: different mutator phenotypes and the principal involvement of hMLH1. Cancer Res (1998) 3.36
RNA-dependent DNA polymerase activity in five RNA viruses: divalent cation requirements. Proc Natl Acad Sci U S A (1970) 3.25
Nucleotide sequence evidence for relationship of AIDS retrovirus to lentiviruses. Nature (1985) 3.13
Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes. Nat Med (2001) 3.07
Cellular transformation and guanine nucleotide exchange activity are catalyzed by a common domain on the dbl oncogene product. J Biol Chem (1994) 3.03
Structural and immunological similarities between simian sarcoma virus gene product(s) and human platelet-derived growth factor. Nature (1983) 3.01
Oncogenes in solid human tumours. Nature (1982) 3.00
Characterization of murine leukaemia virus-specific DNA present in normal mouse cells. Nat New Biol (1973) 2.98
Treatment of neuroendocrine carcinomas with combined etoposide and cisplatin. Evidence of major therapeutic activity in the anaplastic variants of these neoplasms. Cancer (1991) 2.98
Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c-Jun towards cyclin D1. EMBO J (2001) 2.97
Endogenous type-C RNA viruses of mammalian cells. Biochim Biophys Acta (1976) 2.95
Nucleotide sequence of the simian sarcoma virus genome: demonstration that its acquired cellular sequences encode the transforming gene product p28sis. Proc Natl Acad Sci U S A (1983) 2.95
Nucleotide sequence analysis of the transforming region and large terminal redundancies of Moloney murine sarcoma virus. Proc Natl Acad Sci U S A (1980) 2.93
Radiommunoassays for the 70,000-molecular-weight glycoproteins of endogenous mouse type C viruses: viral antigen expression in normal mouse tissues and sera. J Virol (1976) 2.82
Isolation of temperature-sensitive mutants of murine leukemia virus. Virology (1972) 2.78
Phytochelatin synthase genes from Arabidopsis and the yeast Schizosaccharomyces pombe. Plant Cell (1999) 2.74
Molecular cloning of integrated simian sarcoma virus: genome organization of infectious DNA clones. Proc Natl Acad Sci U S A (1981) 2.74
Immunological characterization of primate C-type virus reverse transcriptases. Nat New Biol (1972) 2.73
Treatment of the malignant carcinoid syndrome. Evaluation of a long-acting somatostatin analogue. N Engl J Med (1986) 2.70
Mouse leukemia virus: "spontaneous" release by mouse embryo cells after long-term in vitro cultivation. Proc Natl Acad Sci U S A (1969) 2.68
Immunological relationships of reverse transcriptases from ribonucleic acid tumor viruses. J Virol (1972) 2.65
Failure of high-dose vitamin C (ascorbic acid) therapy to benefit patients with advanced cancer. A controlled trial. N Engl J Med (1979) 2.63
Neoplastic transformation of mast cells by Abelson-MuLV: abrogation of IL-3 dependence by a nonautocrine mechanism. Cell (1985) 2.59
Impact of number of nodes retrieved on outcome in patients with rectal cancer. J Clin Oncol (2001) 2.54
Complete nucleotide sequence and organization of the Moloney murine sarcoma virus genome. Science (1981) 2.51
BRCA1 regulates p53-dependent gene expression. Proc Natl Acad Sci U S A (1998) 2.50
Development of a highly efficient expression cDNA cloning system: application to oncogene isolation. Proc Natl Acad Sci U S A (1991) 2.48
Nature and distribution of feline sarcoma virus nucleotide sequences. J Virol (1979) 2.47
Novel source of 1,2-diacylglycerol elevated in cells transformed by Ha-ras oncogene. Nature (1987) 2.46
Incidence of high blood lead levels in Chicago children. Pediatrics (1969) 2.46
Properties of clonal lines of murine sarcoma virus transformed Balb-3T3 cells. Virology (1969) 2.40
Laparoscopic resection of gastric diverticulum. J Laparoendosc Adv Surg Tech A (1999) 2.39
RNA dependent DNA polymerase activity in mammalian cells. Nature (1971) 2.37
Genetic factors influencing C-type RNA virus induction. J Exp Med (1972) 2.36
Purification and molecular cloning of a secreted, Frizzled-related antagonist of Wnt action. Proc Natl Acad Sci U S A (1997) 2.36
Abelson murine leukemia virus: molecular cloning of infectious integrated proviral DNA. Proc Natl Acad Sci U S A (1981) 2.34
Signal transduction through the EGF receptor transfected in IL-3-dependent hematopoietic cells. Science (1988) 2.29
Major pol gene progenitors in the evolution of oncoviruses. Science (1984) 2.28
Widespread natural occurrence of high titers of neutralizing antibodies to a specific class of endogenous mouse type-C virus. Proc Natl Acad Sci U S A (1974) 2.27
Molecular cloning of Moloney murine sarcoma virus: arrangement of virus-related sequences within the normal mouse genome. Proc Natl Acad Sci U S A (1979) 2.27
Incremental costs of enrolling cancer patients in clinical trials: a population-based study. J Natl Cancer Inst (1999) 2.25
Neoplastic transformation of human epidermal keratinocytes by AD12-SV40 and Kirsten sarcoma viruses. Science (1985) 2.23
The 5' untranslated sequence of the c-sis/platelet-derived growth factor 2 transcript is a potent translational inhibitor. Mol Cell Biol (1988) 2.22
IRS-1: essential for insulin- and IL-4-stimulated mitogenesis in hematopoietic cells. Science (1993) 2.21
Nucleotide sequence analysis of equine infectious anemia virus proviral DNA. Virology (1987) 2.19
Restriction enzyme analysis of mouse cellular type C viral DNA: emergence of new viral sequences in spontaneous AKR/J lymphomas. Proc Natl Acad Sci U S A (1979) 2.18
Segregation of loci for C-type virus induction in strains of mice with high and low incidence of leukemia. Science (1973) 2.17
Amplification and/or overexpression of platelet-derived growth factor receptors and epidermal growth factor receptor in human glial tumors. Cancer Res (1992) 2.17
BALB and Kirsten murine sarcoma viruses alter growth and differentiation of EGF-dependent balb/c mouse epidermal keratinocyte lines. Cell (1983) 2.17
Isolation and biochemical characterization of the human Dkk-1 homologue, a novel inhibitor of mammalian Wnt signaling. J Biol Chem (1999) 2.12
Diverse tumorigenesis associated with aberrant development in mice overexpressing hepatocyte growth factor/scatter factor. Proc Natl Acad Sci U S A (1997) 2.12
Endoscopic resection of submucosal tumor of the esophagus: results in 62 patients. Endoscopy (1997) 2.11
Recommendation for caution with irinotecan, fluorouracil, and leucovorin for colorectal cancer. N Engl J Med (2001) 2.09
Assessment of genetic changes in hepatocellular carcinoma by comparative genomic hybridization analysis: relationship to disease stage, tumor size, and cirrhosis. Am J Pathol (1999) 2.07
Distribution of three classes of endogenous type-C RNA viruses among inbred strains of mice. Virology (1975) 2.07
MyoD induces growth arrest independent of differentiation in normal and transformed cells. Proc Natl Acad Sci U S A (1990) 2.07
Interaction of frizzled related protein (FRP) with Wnt ligands and the frizzled receptor suggests alternative mechanisms for FRP inhibition of Wnt signaling. J Biol Chem (1999) 2.05
Characterization of temperature-sensitive mutants of murine leukemia virus. Virology (1973) 2.05
Transforming genes of human hematopoietic tumors: frequent detection of ras-related oncogenes whose activation appears to be independent of tumor phenotype. Proc Natl Acad Sci U S A (1983) 2.04
Activated oncogenes in B6C3F1 mouse liver tumors: implications for risk assessment. Science (1987) 2.03
Brain metastases from colorectal carcinoma. The long term survivors. Cancer (1996) 2.01