Published in Mol Cell Biol on June 01, 2006
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A cathepsin L isoform that is devoid of a signal peptide localizes to the nucleus in S phase and processes the CDP/Cux transcription factor. Mol Cell (2004) 2.44
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Cathepsin L-deficient mice exhibit abnormal skin and bone development and show increased resistance to osteoporosis following ovariectomy. Int J Exp Pathol (2004) 1.04
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The serpin SQN-5 is a dual mechanistic-class inhibitor of serine and cysteine proteinases. Biochemistry (2002) 0.97
Senescence-initiated reversal of drug resistance: specific role of cathepsin L. Cancer Res (2004) 0.95
Epigenetic heterochromatin markers distinguish terminally differentiated leukocytes from incompletely differentiated leukemia cells in human blood. Exp Hematol (2006) 0.93
Mice that express enzymatically inactive cathepsin L exhibit abnormal spermatogenesis. Biol Reprod (2003) 0.92
Insulation of the chicken beta-globin chromosomal domain from a chromatin-condensing protein, MENT. Mol Cell Biol (2003) 0.84
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Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation. J Cell Biol (2009) 5.27
H2A.Z alters the nucleosome surface to promote HP1alpha-mediated chromatin fiber folding. Mol Cell (2004) 2.63
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A new fluorescence resonance energy transfer approach demonstrates that the histone variant H2AZ stabilizes the histone octamer within the nucleosome. J Biol Chem (2004) 2.33
RNA interference demonstrates a novel role for H2A.Z in chromosome segregation. Nat Struct Mol Biol (2004) 2.33
New insights into nucleosome and chromatin structure: an ordered state or a disordered affair? Nat Rev Mol Cell Biol (2012) 2.14
The replacement histone H2A.Z in a hyperacetylated form is a feature of active genes in the chicken. Nucleic Acids Res (2005) 2.08
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Nucleosomes containing the histone variant H2A.Bbd organize only 118 base pairs of DNA. EMBO J (2004) 1.67
The X and Y chromosomes assemble into H2A.Z-containing [corrected] facultative heterochromatin [corrected] following meiosis. Mol Cell Biol (2006) 1.64
MeCP2-chromatin interactions include the formation of chromatosome-like structures and are altered in mutations causing Rett syndrome. J Biol Chem (2007) 1.60
H2A.Z contributes to the unique 3D structure of the centromere. Proc Natl Acad Sci U S A (2006) 1.45
Inhibition of arginase I activity by RNA interference attenuates IL-13-induced airways hyperresponsiveness. J Immunol (2006) 1.40
Acetylation of H2A.Z is a key epigenetic modification associated with gene deregulation and epigenetic remodeling in cancer. Genome Res (2011) 1.39
Dynamic histone variant exchange accompanies gene induction in T cells. Mol Cell Biol (2009) 1.31
Unique residues on the H2A.Z containing nucleosome surface are important for Xenopus laevis development. J Biol Chem (2004) 1.21
Role of the M-loop and reactive center loop domains in the folding and bridging of nucleosome arrays by MENT. J Biol Chem (2003) 1.18
Inhibitory activity of a heterochromatin-associated serpin (MENT) against papain-like cysteine proteinases affects chromatin structure and blocks cell proliferation. J Biol Chem (2002) 1.17
Chromatin condensation in terminally differentiating mouse erythroblasts does not involve special architectural proteins but depends on histone deacetylation. Chromosome Res (2009) 1.16
Newborn screening and diagnosis of mucopolysaccharidoses. Mol Genet Metab (2013) 1.13
A unique H2A histone variant occupies the transcriptional start site of active genes. Nat Struct Mol Biol (2011) 1.12
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Proteomic assessment of a cell model of spinal muscular atrophy. BMC Neurosci (2011) 1.05
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Specific patterns of histone marks accompany X chromosome inactivation in a marsupial. Chromosome Res (2009) 0.97
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X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation. EMBO J (2006) 0.94
Chondroitin 6-Sulfate as a Novel Biomarker for Mucopolysaccharidosis IVA and VII. JIMD Rep (2014) 0.93
Epigenetic heterochromatin markers distinguish terminally differentiated leukocytes from incompletely differentiated leukemia cells in human blood. Exp Hematol (2006) 0.93
DNA accelerates the inhibition of human cathepsin V by serpins. J Biol Chem (2007) 0.92
Evolution of placentally expressed cathepsins. Biochem Biophys Res Commun (2002) 0.92
Dexamethasone-loaded block copolymer nanoparticles induce leukemia cell death and enhance therapeutic efficacy: a novel application in pediatric nanomedicine. Mol Pharm (2012) 0.91
Histone-mediated transduction as an efficient means for gene delivery. Mol Ther (2007) 0.89
Efficient differentiation of mouse embryonic stem cells into motor neurons. J Vis Exp (2012) 0.87
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Insulation of the chicken beta-globin chromosomal domain from a chromatin-condensing protein, MENT. Mol Cell Biol (2003) 0.84
Developmentally regulated linker histone H1c promotes heterochromatin condensation and mediates structural integrity of rod photoreceptors in mouse retina. J Biol Chem (2013) 0.82
Quantitative analysis of HP1alpha binding to nucleosomal arrays. Methods (2007) 0.82
Induction of cell death in neuroblastoma by inhibition of cathepsins B and L. Cancer Lett (2010) 0.80
Di-sulfated Keratan Sulfate as a Novel Biomarker for Mucopolysaccharidosis II, IVA, and IVB. JIMD Rep (2015) 0.80
Conformational change in the chromatin remodelling protein MENT. PLoS One (2009) 0.78
Identification of the phosphorylation sites in the survival motor neuron protein by protein kinase A. Biochim Biophys Acta (2011) 0.77
Defining the substrate specificity of mouse cathepsin P. Arch Biochem Biophys (2005) 0.76
Inhibitors of cathepsins B and L induce autophagy and cell death in neuroblastoma cells. Invest New Drugs (2012) 0.76
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Development of a specific inhibitor for the placental protease, cathepsin P. Arch Biochem Biophys (2007) 0.75