Published in J Mol Med (Berl) on May 17, 2006
Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review. Exp Gerontol (2008) 1.41
Re-sequencing of the APOAI promoter region and the genetic association of the -75G > A polymorphism with increased cholesterol and low density lipoprotein levels among a sample of the Kuwaiti population. BMC Med Genet (2013) 0.83
Gene-gene combination effect and interactions among ABCA1, APOA1, SR-B1, and CETP polymorphisms for serum high-density lipoprotein-cholesterol in the Japanese population. PLoS One (2013) 0.82
Apolipoprotein C3 polymorphisms, cognitive function and diabetes in Caribbean origin Hispanics. PLoS One (2009) 0.77
Vitamin D dependent effects of APOA5 polymorphisms on HDL cholesterol. Atherosclerosis (2012) 0.77
Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. Circulation (2002) 76.93
Empirical threshold values for quantitative trait mapping. Genetics (1994) 46.95
A comprehensive review of genetic association studies. Genet Med (2002) 16.75
CARDIA: study design, recruitment, and some characteristics of the examined subjects. J Clin Epidemiol (1988) 15.40
Empirical bayes methods and false discovery rates for microarrays. Genet Epidemiol (2002) 10.56
The landscape of genetic complexity across 5,700 gene expression traits in yeast. Proc Natl Acad Sci U S A (2005) 9.66
A combinatorial partitioning method to identify multilocus genotypic partitions that predict quantitative trait variation. Genome Res (2001) 6.06
An Icelandic example of the impact of population structure on association studies. Nat Genet (2004) 5.53
Trends and disparities in coronary heart disease, stroke, and other cardiovascular diseases in the United States: findings of the national conference on cardiovascular disease prevention. Circulation (2000) 5.41
Categorization of humans in biomedical research: genes, race and disease. Genome Biol (2002) 4.84
Enzymatic methods for quantification of lipoprotein lipids. Methods Enzymol (1986) 3.31
Sex differences in coronary heart disease. Why are women so superior? The 1995 Ancel Keys Lecture. Circulation (1997) 2.74
Population structure, admixture, and aging-related phenotypes in African American adults: the Cardiovascular Health Study. Am J Hum Genet (2005) 2.41
Genes, environment, and cardiovascular disease. Arterioscler Thromb Vasc Biol (2003) 2.04
Modulation of lipoprotein lipase activity by apolipoproteins. Effect of apolipoprotein C-III. J Clin Invest (1985) 1.79
Linkage disequilibrium patterns vary substantially among populations. Eur J Hum Genet (2005) 1.73
Meta-analysis. Unresolved issues and future developments. BMJ (1998) 1.69
Health behaviors of adults: United States, 1999-2001. Vital Health Stat 10 (2004) 1.63
Regional disparities in the incidence of elevated blood pressure among young adults: the CARDIA study. Circulation (1997) 1.58
Ethnicity and human genetic linkage maps. Am J Hum Genet (2004) 1.50
Plasma high-density lipoproteins. N Engl J Med (1978) 1.44
Apolipoproteins of HDL can directly mediate binding to the scavenger receptor SR-BI, an HDL receptor that mediates selective lipid uptake. J Lipid Res (1997) 1.30
High density lipoprotein structure. Front Biosci (2003) 1.22
The apoAI-CIII-AIV gene cluster. Atherosclerosis (2001) 1.20
Contribution of apolipoprotein C-III gene variants to determination of triglyceride levels and interaction with smoking in middle-aged men. Arterioscler Thromb Vasc Biol (2000) 1.12
The effects of scale: variation in the APOA1/C3/A4/A5 gene cluster. Hum Genet (2004) 1.07
Genetic architecture of inter-individual variability in apolipoprotein, lipoprotein and lipid phenotypes. Ciba Found Symp (1987) 1.03
Evidence for consistent intragenic and intergenic interactions between SNP effects in the APOA1/C3/A4/A5 gene cluster. Hum Hered (2006) 1.01
The emperor's new methods. Am J Hum Genet (2003) 0.99
Genetic determinants of low high-density lipoprotein cholesterol. Curr Opin Cardiol (2004) 0.94
Genetic association of five apolipoprotein polymorphisms with serum lipoprotein-lipid levels in African blacks. Genet Epidemiol (1999) 0.93
Haplotype analysis of two APOA1/MspI polymorphisms in relation to plasma levels of apo A-I and HDL-cholesterol. Atherosclerosis (1996) 0.91
Gender related association between genetic variations of APOC-III gene and lipid and lipoprotein variables in northern France. Atherosclerosis (2000) 0.89
High-density lipoprotein metabolism and progression of atherosclerosis: new insights from the HDL Atherosclerosis Treatment Study. Curr Opin Cardiol (2004) 0.88
Evidence for non-additive influence of single nucleotide polymorphisms within the apolipoprotein E gene. Ann Hum Genet (2004) 0.88
Genetic influences on lipid metabolism trait variability within the Stanislas Cohort. J Lipid Res (2001) 0.87
Effects of apolipoprotein A-I genetic variations on plasma apolipoprotein, serum lipoprotein and glucose levels. Clin Genet (2002) 0.84
Differences in cardiovascular disease risk factors in black and white young adults: comparisons among five communities of the CARDIA and the Bogalusa heart studies. Coronary Artery Risk Development In Young Adults. Ann Epidemiol (1998) 0.81
An association analysis between ApoA1 polymorphisms and the high-density lipoprotein (HDL) cholesterol level and myocardial infarction (MI) in Japanese. J Hum Genet (2004) 0.81
Genetic epidemiology: some special contributions of birth cohorts. Paediatr Perinat Epidemiol (2004) 0.81
Prevalence of the APOC3 promoter polymorphisms T-455C and C-482T in Asian-Indians. Am J Cardiol (2001) 0.80
Variation at the lipoprotein lipase and apolipoprotein AI-CIII gene loci are associated with fasting lipid and lipoprotein traits in a population sample from Iceland: interaction between genotype, gender, and smoking status. Genet Epidemiol (1997) 0.79
Comparison of commercial kits for apoprotein A-I and apoprotein B with standardized apoprotein A-I and B radioimmunoassays performed at the Northwest Lipid Research Center. J Lipid Res (1988) 0.77
The sequence of the human genome. Science (2001) 101.55
DNA sequence diversity in a 9.7-kb region of the human lipoprotein lipase gene. Nat Genet (1998) 11.70
Sequence variation in the human angiotensin converting enzyme. Nat Genet (1999) 10.12
A cladistic analysis of phenotypic associations with haplotypes inferred from restriction endonuclease mapping and DNA sequence data. III. Cladogram estimation. Genetics (1992) 10.09
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nat Genet (2013) 9.46
Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus. Nat Genet (2000) 8.33
VNTR allele frequency distributions under the stepwise mutation model: a computer simulation approach. Genetics (1993) 8.22
Haplotype diversity and linkage disequilibrium at human G6PD: recent origin of alleles that confer malarial resistance. Science (2001) 7.87
Haplotype structure and population genetic inferences from nucleotide-sequence variation in human lipoprotein lipase. Am J Hum Genet (1998) 7.56
A genome-wide search for human non-insulin-dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2. Nat Genet (1996) 6.58
A combinatorial partitioning method to identify multilocus genotypic partitions that predict quantitative trait variation. Genome Res (2001) 6.06
Apolipoprotein E polymorphism and atherosclerosis. Arteriosclerosis (1988) 6.01
The use of measured genotype information in the analysis of quantitative phenotypes in man. I. Models and analytical methods. Ann Hum Genet (1986) 5.02
Population structure in admixed populations: effect of admixture dynamics on the pattern of linkage disequilibrium. Am J Hum Genet (2000) 4.74
Assessing genetic linkage and association with robust components of variance approaches. Ann Hum Genet (1996) 4.41
Circulating adhesion molecules VCAM-1, ICAM-1, and E-selectin in carotid atherosclerosis and incident coronary heart disease cases: the Atherosclerosis Risk In Communities (ARIC) study. Circulation (1997) 4.41
Evolutionary EST analysis identifies rapidly evolving male reproductive proteins in Drosophila. Proc Natl Acad Sci U S A (2001) 4.15
Genetic and environmental contributions to cardiovascular risk factors in Mexican Americans. The San Antonio Family Heart Study. Circulation (1996) 4.10
Role of the apolipoprotein E polymorphism in determining normal plasma lipid and lipoprotein variation. Am J Hum Genet (1985) 3.81
Local rates of recombination are positively correlated with GC content in the human genome. Mol Biol Evol (2001) 3.39
A major quantitative trait locus determining serum leptin levels and fat mass is located on human chromosome 2. Nat Genet (1997) 3.37
Relation of serum lipoprotein(a) concentration and apolipoprotein(a) phenotype to coronary heart disease in patients with familial hypercholesterolemia. N Engl J Med (1990) 3.17
Measurement of gastrointestinal pH profiles in normal ambulant human subjects. Gut (1988) 3.14
Polymorphism at the self-incompatibility locus in Solanaceae predates speciation. Proc Natl Acad Sci U S A (1990) 2.91
Recombinational and mutational hotspots within the human lipoprotein lipase gene. Am J Hum Genet (2000) 2.83
The structure of human mitochondrial DNA variation. J Mol Evol (1991) 2.78
The unit of selection in Drosophila mercatorum. I. The interation of selection and meiosis in parthenogenetic strains. Genetics (1976) 2.71
A cladistic analysis of phenotype associations with haplotypes inferred from restriction endonuclease mapping. II. The analysis of natural populations. Genetics (1988) 2.68
A novel measure of genetic distance for highly polymorphic tandem repeat loci. Mol Biol Evol (1995) 2.65
Apolipoprotein E variation at the sequence haplotype level: implications for the origin and maintenance of a major human polymorphism. Am J Hum Genet (2000) 2.62
The population genetics of parthenogenetic strains of Drosophila mercatorium. II The capacity for parthenogenesis in a natural, bisexual population. Genetics (1976) 2.56
Comparisons of ape and human sequences that regulate mitochondrial DNA transcription and D-loop DNA synthesis. Nucleic Acids Res (1988) 2.54
Sequence diversity and large-scale typing of SNPs in the human apolipoprotein E gene. Genome Res (2000) 2.53
A cladistic analysis of phenotypic associations with haplotypes inferred from restriction endonuclease mapping. IV. Nested analyses with cladogram uncertainty and recombination. Genetics (1993) 2.52
Mapping and sequence of the gene for the pseudorabies virus glycoprotein which accumulates in the medium of infected cells. J Virol (1985) 2.43
Analysis of multilocus genetic systems in Tecumseh, Michigan. II. Consideration of the correlation between nonalleles in gametes. Am J Hum Genet (1972) 2.32
Validity of the aldosterone-renin ratio used to screen for primary aldosteronism. Mayo Clin Proc (2001) 2.19
Allelic variation in human mitochondrial genes based on patterns of restriction site polymorphism. Proc Natl Acad Sci U S A (1986) 2.13
Identification of five new genes on the Y chromosome of Drosophila melanogaster. Proc Natl Acad Sci U S A (2001) 2.09
Feature (gene) selection in gene expression-based tumor classification. Mol Genet Metab (2001) 2.08
Molecular population genetics of male accessory gland proteins in Drosophila. Genetics (2000) 2.02
A model for analysis of population structure. Genetics (1974) 2.02
Natural selection with nuclear and cytoplasmic transmission. I. A deterministic model. Genetics (1984) 1.99
Y chromosomal fertility factors kl-2 and kl-3 of Drosophila melanogaster encode dynein heavy chain polypeptides. Proc Natl Acad Sci U S A (2000) 1.97
Genetic conflicts, multiple paternity and the evolution of genomic imprinting. Genetics (1998) 1.97
Intron size and natural selection. Nature (1999) 1.96
Alternative splicing switches potassium channel sensitivity to protein phosphorylation. J Biol Chem (2001) 1.95
Sequence variation and linkage disequilibrium in the human T-cell receptor beta (TCRB) locus. Am J Hum Genet (2001) 1.91
The apolipoprotein E polymorphism: a comparison of allele frequencies and effects in nine populations. Am J Hum Genet (1991) 1.88
Short tandem-repeat polymorphism/alu haplotype variation at the PLAT locus: implications for modern human origins. Am J Hum Genet (2000) 1.85
Genome-wide linkage analyses of systolic blood pressure using highly discordant siblings. Circulation (1999) 1.81
High-throughput multiplex SNP genotyping with MALDI-TOF mass spectrometry: practice, problems and promise. Hum Mutat (2001) 1.80
Species differences in the inhibition of glutathione S-aryltransferase by phthaleins and dicarboxylic acids. Biochem J (1967) 1.79
Cross-species comparison of Drosophila male accessory gland protein genes. Genetics (2005) 1.71
Anticipation in myotonic dystrophy. I. Statistical verification based on clinical and haplotype findings. Neurology (1992) 1.70
Familial thoracic aortic aneurysms and dissections: genetic heterogeneity with a major locus mapping to 5q13-14. Circulation (2001) 1.69
The size distribution of homozygous segments in the human genome. Am J Hum Genet (1999) 1.68
Molecular basis of apolipoprotein (a) isoform size heterogeneity as revealed by pulsed-field gel electrophoresis. J Clin Invest (1991) 1.68
Variation in the region of the angiotensin-converting enzyme gene influences interindividual differences in blood pressure levels in young white males. Circulation (1998) 1.65
Bias of the contribution of single-locus effects to the variance of a quantitative trait. Am J Hum Genet (1986) 1.65
Sexually antagonistic cytonuclear fitness interactions in Drosophila melanogaster. Genetics (2001) 1.65
Plasma lipid, lipoprotein cholesterol, and apoprotein distributions in selected US communities. The Atherosclerosis Risk in Communities (ARIC) Study. Arterioscler Thromb (1993) 1.65
Constraints on intron evolution in the gene encoding the myosin alkali light chain in Drosophila. Genetics (1995) 1.64
Cladistic structure within the human Lipoprotein lipase gene and its implications for phenotypic association studies. Genetics (2000) 1.64
Microsatellite variation in North American populations of Drosophila melanogaster. Nucleic Acids Res (1995) 1.63
Differential selection after duplication in mammalian developmental genes. Mol Biol Evol (2001) 1.63
Genetics of atherosclerosis risk factors in Mexican Americans. Nutr Rev (1999) 1.61
Some genetic programs to supplement self-instruction in FORTRAN. Am J Hum Genet (1967) 1.60
Effects of the apolipoprotein(a) size polymorphism on the lipoprotein(a) concentration in 7 ethnic groups. Hum Genet (1991) 1.59
Negotiating the transition to middle school: the role of self-regulatory processes. Child Dev (2001) 1.59
APOE genotype and cognitive decline in a middle-aged cohort. Neurology (2005) 1.54
Natural selection and Y-linked polymorphism. Genetics (1987) 1.47
Studies on genetic selection in a completely ascertained caucasian population. II. Family analyses of 11 blood group systems. Am J Hum Genet (1971) 1.46
Computational methods for gene expression-based tumor classification. Biotechniques (2000) 1.45
Studies on genetic selection in a completely ascertained caucasian population. I. Frequencies, age and sex effects, and phenotype associations for 12 blood group systems. Am J Hum Genet (1971) 1.44
Comparison of model-free linkage mapping strategies for the study of a complex trait. Genet Epidemiol (1997) 1.44
Analysis of genetic and environmental sources of variation in serum cholesterol in Tecumseh, Michigan. III. Identification of genetic effects using 12 polymorphic genetic blood marker systems. Am J Hum Genet (1976) 1.42
Ribosomal DNA and Stellate gene copy number variation on the Y chromosome of Drosophila melanogaster. Proc Natl Acad Sci U S A (1989) 1.41
Evidence for recurrent paralogous gene conversion and exceptional allelic divergence in the Attacin genes of Drosophila melanogaster. Genetics (2001) 1.40
Cardiovascular instability requiring treatment after intravenous heparin for cardiopulmonary bypass. Anesth Analg (2000) 1.39
Studies of isozyme patterns in nullisomic-tetrasomic combinations of hexaploid wheat. Proc Natl Acad Sci U S A (1969) 1.38
Non-Mendelian segregation of sex chromosomes in heterospecific Drosophila males. Genetics (2000) 1.37