Published in Proc Natl Acad Sci U S A on June 05, 2006
Diverse type VI secretion phospholipases are functionally plastic antibacterial effectors. Nature (2013) 2.11
Outer membrane adhesion factor multivalent adhesion molecule 7 initiates host cell binding during infection by gram-negative pathogens. Proc Natl Acad Sci U S A (2011) 1.97
A new Vibrio cholerae sRNA modulates colonization and affects release of outer membrane vesicles. Mol Microbiol (2008) 1.83
Specificity and complexity of the Caenorhabditis elegans innate immune response. Mol Cell Biol (2007) 1.78
A quorum-sensing antagonist targets both membrane-bound and cytoplasmic receptors and controls bacterial pathogenicity. Mol Cell (2009) 1.55
Quorum sensing regulation of the two hcp alleles in Vibrio cholerae O1 strains. PLoS One (2009) 1.37
Hypoxia and the hypoxic response pathway protect against pore-forming toxins in C. elegans. PLoS Pathog (2009) 1.35
RAB-5- and RAB-11-dependent vesicle-trafficking pathways are required for plasma membrane repair after attack by bacterial pore-forming toxin. Cell Host Microbe (2011) 1.35
Caenorhabditis elegans genomic response to soil bacteria predicts environment-specific genetic effects on life history traits. PLoS Genet (2009) 1.31
Regulatory targets of quorum sensing in Vibrio cholerae: evidence for two distinct HapR-binding motifs. Nucleic Acids Res (2009) 1.28
Proteomic analysis of the Vibrio cholerae type II secretome reveals new proteins, including three related serine proteases. J Biol Chem (2011) 1.20
Pathoadaptive conditional regulation of the type VI secretion system in Vibrio cholerae O1 strains. Infect Immun (2011) 1.20
Genomic and proteomic analyses of the coral pathogen Vibrio coralliilyticus reveal a diverse virulence repertoire. ISME J (2011) 1.14
Comparative genomics of clinical and environmental Vibrio mimicus. Proc Natl Acad Sci U S A (2010) 1.13
Environmental reservoirs and mechanisms of persistence of Vibrio cholerae. Front Microbiol (2013) 1.13
Role of melanin pigment in expression of Vibrio cholerae virulence factors. Infect Immun (2008) 1.11
An experimental study of the population and evolutionary dynamics of Vibrio cholerae O1 and the bacteriophage JSF4. Proc Biol Sci (2010) 1.00
Role of the Vibrio cholerae matrix protein Bap1 in cross-resistance to antimicrobial peptides. PLoS Pathog (2013) 0.99
Levels of the secreted Vibrio cholerae attachment factor GbpA are modulated by quorum-sensing-induced proteolysis. J Bacteriol (2009) 0.98
Quorum sensing negatively regulates hemolysin transcriptionally and posttranslationally in Vibrio cholerae. Infect Immun (2009) 0.93
Studies on a novel serine protease of a ΔhapAΔprtV Vibrio cholerae O1 strain and its role in hemorrhagic response in the rabbit ileal loop model. PLoS One (2010) 0.90
The metalloprotease PrtV from Vibrio cholerae. FEBS J (2008) 0.89
NOD-like receptor activation by outer membrane vesicles from Vibrio cholerae non-O1 non-O139 strains is modulated by the quorum-sensing regulator HapR. Infect Immun (2011) 0.89
Vibrio cholerae hemolysin is required for lethality, developmental delay, and intestinal vacuolation in Caenorhabditis elegans. PLoS One (2010) 0.88
Genomic analysis of immune response against Vibrio cholerae hemolysin in Caenorhabditis elegans. PLoS One (2012) 0.88
Outer membrane vesicles mediate transport of biologically active Vibrio cholerae cytolysin (VCC) from V. cholerae strains. PLoS One (2014) 0.87
Vibrio cholerae cytolysin causes an inflammatory response in human intestinal epithelial cells that is modulated by the PrtV protease. PLoS One (2009) 0.87
Synergistic effect of various virulence factors leading to high toxicity of environmental V. cholerae non-O1/ non-O139 isolates lacking ctx gene : comparative study with clinical strains. PLoS One (2013) 0.85
Alkaline pH Is a signal for optimal production and secretion of the heat labile toxin, LT in enterotoxigenic Escherichia coli (ETEC). PLoS One (2013) 0.85
Interaction between Vibrio mimicus and Acanthamoeba castellanii. Environ Microbiol Rep (2010) 0.84
Cranberry extract standardized for proanthocyanidins promotes the immune response of Caenorhabditis elegans to Vibrio cholerae through the p38 MAPK pathway and HSF-1. PLoS One (2014) 0.84
Quorum sensing-regulated chitin metabolism provides grazing resistance to Vibrio cholerae biofilms. ISME J (2015) 0.82
Relative contributions of Vibrio polysaccharide and quorum sensing to the resistance of Vibrio cholerae to predation by heterotrophic protists. PLoS One (2013) 0.82
Calcium binding by the PKD1 domain regulates interdomain flexibility in Vibrio cholerae metalloprotease PrtV. FEBS Open Bio (2013) 0.82
Outer Membrane Vesicle-Mediated Export of Processed PrtV Protease from Vibrio cholerae. PLoS One (2015) 0.82
Neuronal Goα and CAPS regulate behavioral and immune responses to bacterial pore-forming toxins. PLoS One (2013) 0.81
Characterization of the secretomes of two vibrios pathogenic to mollusks. PLoS One (2014) 0.81
The VrrA sRNA controls a stationary phase survival factor Vrp of Vibrio cholerae. RNA Biol (2015) 0.80
The microcosm mediates the persistence of shiga toxin-producing Escherichia coli in freshwater ecosystems. Appl Environ Microbiol (2013) 0.80
Quorum sensing regulatory cascades control Vibrio fluvialis pathogenesis. J Bacteriol (2013) 0.80
"Quorum Non-Sensing": Social Cheating and Deception in Vibrio cholerae. Appl Environ Microbiol (2015) 0.80
Staying Alive: Vibrio cholerae's Cycle of Environmental Survival, Transmission, and Dissemination. Microbiol Spectr (2016) 0.79
Environmental proteomics, biodiversity statistics and food-web structure. Trends Ecol Evol (2012) 0.79
A metalloprotease secreted by the type II secretion system links Vibrio cholerae with collagen. J Bacteriol (2015) 0.79
Structure of the N-terminal domain of the metalloprotease PrtV from Vibrio cholerae. Protein Sci (2015) 0.78
Comparative proteomics of two Vibrio anguillarum serotype O1 strains with different virulence phenotypes. Curr Microbiol (2012) 0.77
Bacteria can mobilize nematode-trapping fungi to kill nematodes. Nat Commun (2014) 0.76
Cytotoxic and Inflammatory Responses Induced by Outer Membrane Vesicle-Associated Biologically Active Proteases from Vibrio cholerae. Infect Immun (2016) 0.76
Molecular and chemical dialogues in bacteria-protozoa interactions. Sci Rep (2015) 0.76
Induction of immunomodulatory miR-146a and miR-155 in small intestinal epithelium of Vibrio cholerae infected patients at acute stage of cholera. PLoS One (2017) 0.75
An Enterotoxin-like Binary Protein from Pseudomonas protegens with Potent Nematicidal Activity. Appl Environ Microbiol (2017) 0.75
Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci U S A (1979) 365.71
The genetics of Caenorhabditis elegans. Genetics (1974) 102.14
Survival strategies of bacteria in the natural environment. Microbiol Rev (1987) 18.16
Cholera. Clin Microbiol Rev (1995) 12.33
The Comprehensive Microbial Resource. Nucleic Acids Res (2001) 11.19
Global climate and infectious disease: the cholera paradigm. Science (1996) 10.08
Identification of a conserved bacterial protein secretion system in Vibrio cholerae using the Dictyostelium host model system. Proc Natl Acad Sci U S A (2006) 7.99
Ecological relationships between Vibrio cholerae and planktonic crustacean copepods. Appl Environ Microbiol (1983) 7.52
Quorum-sensing regulators control virulence gene expression in Vibrio cholerae. Proc Natl Acad Sci U S A (2002) 6.10
Positive selection vectors for allelic exchange. Gene (1996) 5.97
Parallel quorum sensing systems converge to regulate virulence in Vibrio cholerae. Cell (2002) 5.12
Pseudomonas aeruginosa killing of Caenorhabditis elegans used to identify P. aeruginosa virulence factors. Proc Natl Acad Sci U S A (1999) 5.10
Quorum sensing-dependent biofilms enhance colonization in Vibrio cholerae. Dev Cell (2003) 4.42
Significance of predation by protists in aquatic microbial food webs. Antonie Van Leeuwenhoek (2002) 4.29
Salmonella typhimurium proliferates and establishes a persistent infection in the intestine of Caenorhabditis elegans. Curr Biol (2000) 3.31
Detection of Vibrio cholerae O1 in the aquatic environment by fluorescent-monoclonal antibody and culture methods. Appl Environ Microbiol (1990) 3.21
Lethal paralysis of Caenorhabditis elegans by Pseudomonas aeruginosa. Proc Natl Acad Sci U S A (1999) 3.19
Critical factors influencing the occurrence of Vibrio cholerae in the environment of Bangladesh. Appl Environ Microbiol (2005) 3.17
Environmental reservoir of Vibrio cholerae. The causative agent of cholera. Ann N Y Acad Sci (1994) 2.92
Virulence factors of the human opportunistic pathogen Serratia marcescens identified by in vivo screening. EMBO J (2003) 2.87
Regulation of virulence gene expression in Vibrio cholerae by quorum sensing: HapR functions at the aphA promoter. Mol Microbiol (2002) 2.69
Off the hook--how bacteria survive protozoan grazing. Trends Microbiol (2005) 2.59
Caenorhabditis elegans is a model host for Salmonella typhimurium. Curr Biol (2000) 2.48
Biofilm formation and phenotypic variation enhance predation-driven persistence of Vibrio cholerae. Proc Natl Acad Sci U S A (2005) 2.15
Predictability of Vibrio cholerae in Chesapeake Bay. Appl Environ Microbiol (2003) 2.15
Initial clinical studies of CVD 112 Vibrio cholerae O139 live oral vaccine: safety and efficacy against experimental challenge. J Infect Dis (1995) 2.10
Characterization of mediators of microbial virulence and innate immunity using the Caenorhabditis elegans host-pathogen model. Cell Microbiol (2003) 1.70
Environmental signals controlling production of hemagglutinin/protease in Vibrio cholerae. Infect Immun (2001) 1.61
Microcolonies, quorum sensing and cytotoxicity determine the survival of Pseudomonas aeruginosa biofilms exposed to protozoan grazing. Environ Microbiol (2004) 1.52
Tackling both sides of the host-pathogen equation with Caenorhabditis elegans. Microbes Infect (2002) 1.44
Transcriptional regulation of Vibrio cholerae hemagglutinin/protease by the cyclic AMP receptor protein and RpoS. J Bacteriol (2004) 1.41
Microbial diversity: the importance of exploration and conservation. J Ind Microbiol Biotechnol (1997) 1.18
Interaction with decay-accelerating factor facilitates coxsackievirus B infection of polarized epithelial cells. J Virol (2002) 1.14
Characterization of the Vibrio cholerae El Tor lipase operon lipAB and a protease gene downstream of the hly region. J Bacteriol (1997) 1.11
Effects of hydrophobic and electrostatic cell surface properties of bacteria on feeding rates of heterotrophic nanoflagellates. Appl Environ Microbiol (2001) 1.09
Pseudomonas aeruginosa protease IV degrades surfactant proteins and inhibits surfactant host defense and biophysical functions. Am J Physiol Lung Cell Mol Physiol (2004) 1.06
A review of the current status of enteric vaccines. P N G Med J (1995) 1.02
Cloning and genetic analysis of the Vibrio cholerae aminopeptidase gene. Infect Immun (1996) 1.00
Induction of interleukin-8 in T84 cells by Vibrio cholerae. Infect Immun (2004) 0.89
Characteristics of Vibrio cholerae proteinases: potential, candidate vaccine antigens. Vaccine (2004) 0.80
Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med (2009) 39.97
Apixaban versus warfarin in patients with atrial fibrillation. N Engl J Med (2011) 23.50
Genetics of gene expression and its effect on disease. Nature (2008) 21.35
Mapping the genetic architecture of gene expression in human liver. PLoS Biol (2008) 19.44
Variations in DNA elucidate molecular networks that cause disease. Nature (2008) 12.04
An integrative genomics approach to infer causal associations between gene expression and disease. Nat Genet (2005) 11.40
Apixaban in patients with atrial fibrillation. N Engl J Med (2011) 9.97
Dronedarone in high-risk permanent atrial fibrillation. N Engl J Med (2011) 8.93
MicroRNA-mediated feedback and feedforward loops are recurrent network motifs in mammals. Mol Cell (2007) 5.67
Early versus delayed invasive intervention in acute coronary syndromes. N Engl J Med (2009) 4.83
Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages. PLoS Pathog (2007) 4.73
Arsenic degrades PML or PML-RARalpha through a SUMO-triggered RNF4/ubiquitin-mediated pathway. Nat Cell Biol (2008) 4.68
A generalized combinatorial approach for detecting gene-by-gene and gene-by-environment interactions with application to nicotine dependence. Am J Hum Genet (2007) 4.46
Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease. Cell (2013) 4.45
Vesicle-mediated export and assembly of pore-forming oligomers of the enterobacterial ClyA cytotoxin. Cell (2003) 3.88
Genetic heterogeneity of diffuse large B-cell lymphoma. Proc Natl Acad Sci U S A (2013) 3.25
Bortezomib-based therapy for newly diagnosed mantle-cell lymphoma. N Engl J Med (2015) 3.18
Glucose-insulin-potassium therapy in patients with ST-segment elevation myocardial infarction. JAMA (2007) 3.09
A survey of the genetics of stomach, liver, and adipose gene expression from a morbidly obese cohort. Genome Res (2011) 3.00
Validation of candidate causal genes for obesity that affect shared metabolic pathways and networks. Nat Genet (2009) 2.97
Eradication of acute promyelocytic leukemia-initiating cells through PML-RARA degradation. Nat Med (2008) 2.85
BioMagResBank database with sets of experimental NMR constraints corresponding to the structures of over 1400 biomolecules deposited in the Protein Data Bank. J Biomol NMR (2003) 2.74
The Long-Term Multicenter Observational Study of Dabigatran Treatment in Patients With Atrial Fibrillation (RELY-ABLE) Study. Circulation (2013) 2.64
China's facility-based birth strategy and neonatal mortality: a population-based epidemiological study. Lancet (2011) 2.64
Integrating QTL and high-density SNP analyses in mice to identify Insig2 as a susceptibility gene for plasma cholesterol levels. Genomics (2005) 2.61
QTLNetwork: mapping and visualizing genetic architecture of complex traits in experimental populations. Bioinformatics (2008) 2.57
CsrA and three redundant small RNAs regulate quorum sensing in Vibrio cholerae. Mol Microbiol (2005) 2.56
Dabigatran versus warfarin: effects on ischemic and hemorrhagic strokes and bleeding in Asians and non-Asians with atrial fibrillation. Stroke (2013) 2.52
Association analyses identify six new psoriasis susceptibility loci in the Chinese population. Nat Genet (2010) 2.41
ToxR regulon of Vibrio cholerae and its expression in vibrios shed by cholera patients. Proc Natl Acad Sci U S A (2003) 2.29
Mapping the genetic architecture of complex traits in experimental populations. Bioinformatics (2007) 2.27
A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II. Mol Cell (2004) 2.27
Presence of bacteria and innate immunity of intestinal epithelium in childhood celiac disease. Am J Gastroenterol (2004) 2.25
Prevalence of and risk factors for fatty liver in a general population of Shanghai, China. J Hepatol (2005) 2.21
Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. Blood (2010) 2.15
A paired-end sequencing strategy to map the complex landscape of transcription initiation. Nat Methods (2010) 2.14
Diverse type VI secretion phospholipases are functionally plastic antibacterial effectors. Nature (2013) 2.11
Paradoxical coexpression of proinflammatory and down-regulatory cytokines in intestinal T cells in childhood celiac disease. Gastroenterology (2002) 2.11
Detection of minor drug-resistant populations by parallel allele-specific sequencing. Nat Methods (2007) 2.09
Systematic genetic and genomic analysis of cytochrome P450 enzyme activities in human liver. Genome Res (2010) 2.06
Nuclear export and retention signals in the RS domain of SR proteins. Mol Cell Biol (2002) 2.04
Elucidating the murine brain transcriptional network in a segregating mouse population to identify core functional modules for obesity and diabetes. J Neurochem (2006) 2.00
Bidirectional control of social hierarchy by synaptic efficacy in medial prefrontal cortex. Science (2011) 1.97
Metabolism of bile salts in mice influences spore germination in Clostridium difficile. PLoS One (2010) 1.87
Disentangling molecular relationships with a causal inference test. BMC Genet (2009) 1.84
A new Vibrio cholerae sRNA modulates colonization and affects release of outer membrane vesicles. Mol Microbiol (2008) 1.83
Alkylresorcinols as biomarkers of whole-grain wheat and rye intake: plasma concentration and intake estimated from dietary records. Am J Clin Nutr (2008) 1.83
Genetic and phenotypic diversity of quorum-sensing systems in clinical and environmental isolates of Vibrio cholerae. Infect Immun (2006) 1.82
Multi-tissue coexpression networks reveal unexpected subnetworks associated with disease. Genome Biol (2009) 1.77
Cancer cell dependence on unsaturated fatty acids implicates stearoyl-CoA desaturase as a target for cancer therapy. Mol Cancer Res (2011) 1.76
Forkhead transcription factor foxq1 promotes epithelial-mesenchymal transition and breast cancer metastasis. Cancer Res (2011) 1.71
Distribution of putative adhesins in different seropathotypes of Shiga toxin-producing Escherichia coli. J Clin Microbiol (2004) 1.70
Long-range polony haplotyping of individual human chromosome molecules. Nat Genet (2006) 1.69
Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC. Nat Genet (2010) 1.69
Multiplex PCR assay for identification of human diarrheagenic Escherichia coli. J Clin Microbiol (2003) 1.66
A Bayesian partition method for detecting pleiotropic and epistatic eQTL modules. PLoS Comput Biol (2010) 1.66
PML nuclear bodies and apoptosis. Oncogene (2004) 1.66
ASNA-1 positively regulates insulin secretion in C. elegans and mammalian cells. Cell (2007) 1.64
Mucosal penetration primes Vibrio cholerae for host colonization by repressing quorum sensing. Proc Natl Acad Sci U S A (2008) 1.63
Defects in tRNA modification associated with neurological and developmental dysfunctions in Caenorhabditis elegans elongator mutants. PLoS Genet (2009) 1.62
Transcription factor AtMYB103 is required for anther development by regulating tapetum development, callose dissolution and exine formation in Arabidopsis. Plant J (2007) 1.58
A combinatorial approach to detecting gene-gene and gene-environment interactions in family studies. Am J Hum Genet (2008) 1.57
Surface-plasmon-enhanced GaN-LED based on a multilayered M-shaped nano-grating. Opt Express (2013) 1.56
Bile acids stimulate biofilm formation in Vibrio cholerae. Mol Microbiol (2006) 1.56
Antibiotic resistance conferred by a class I integron and SXT constin in Vibrio cholerae O1 strains isolated in Laos. Antimicrob Agents Chemother (2004) 1.56
A splicing-independent function of SF2/ASF in microRNA processing. Mol Cell (2010) 1.55
Association between green tea intake and coronary artery disease in a Chinese population. Circ J (2009) 1.54
RUPTURED POLLEN GRAIN1, a member of the MtN3/saliva gene family, is crucial for exine pattern formation and cell integrity of microspores in Arabidopsis. Plant Physiol (2008) 1.54
Characterization of endogenous human promyelocytic leukemia isoforms. Cancer Res (2006) 1.52
A constitutively active variant of the quorum-sensing regulator LuxO affects protease production and biofilm formation in Vibrio cholerae. Infect Immun (2003) 1.50
Cross-talk between JNK/SAPK and ERK/MAPK pathways: sustained activation of JNK blocks ERK activation by mitogenic factors. J Biol Chem (2003) 1.49
Genome-wide interaction-based association analysis identified multiple new susceptibility Loci for common diseases. PLoS Genet (2011) 1.46
Ultrastructural evidence of mitochondrial abnormalities in postresuscitation myocardial dysfunction. Resuscitation (2011) 1.46
Active cytotoxic necrotizing factor 1 associated with outer membrane vesicles from uropathogenic Escherichia coli. Infect Immun (2006) 1.45
Prediabetes and short-term outcomes in nondiabetic patients after acute ST-elevation myocardial infarction. Cardiology (2013) 1.44
Rho and ROCK signaling in VEGF-induced microvascular endothelial hyperpermeability. Microcirculation (2006) 1.44
Highly efficient extraction of serum peptides by ordered mesoporous carbon. Angew Chem Int Ed Engl (2011) 1.43
Exploration of human, rat, and rabbit embryonic cardiomyocytes suggests K-channel block as a common teratogenic mechanism. Cardiovasc Res (2012) 1.42
Significance of 14-3-3 self-dimerization for phosphorylation-dependent target binding. Mol Biol Cell (2003) 1.42
Type VI secretion modulates quorum sensing and stress response in Vibrio anguillarum. Environ Microbiol (2009) 1.41
Transcription initiation patterns indicate divergent strategies for gene regulation at the chromatin level. PLoS Genet (2011) 1.41
The iron-binding protein Dps confers hydrogen peroxide stress resistance to Campylobacter jejuni. J Bacteriol (2003) 1.41
Release of the type I secreted alpha-haemolysin via outer membrane vesicles from Escherichia coli. Mol Microbiol (2006) 1.41
PfSETvs methylation of histone H3K36 represses virulence genes in Plasmodium falciparum. Nature (2013) 1.40
Lobelane analogues as novel ligands for the vesicular monoamine transporter-2. Bioorg Med Chem (2005) 1.38
Quorum sensing regulation of the two hcp alleles in Vibrio cholerae O1 strains. PLoS One (2009) 1.37
Characterization of a pore-forming cytotoxin expressed by Salmonella enterica serovars typhi and paratyphi A. Infect Immun (2002) 1.36
Subtype-selective nicotinic receptor antagonists: potential as tobacco use cessation agents. Bioorg Med Chem Lett (2004) 1.36
S6K links cell fate, cell cycle and nutrient response in C. elegans germline stem/progenitor cells. Development (2012) 1.35
The HcrVf2 gene from a wild apple confers scab resistance to a transgenic cultivated variety. Proc Natl Acad Sci U S A (2004) 1.32
Nitrogen-doped graphene: beyond single substitution and enhanced molecular sensing. Sci Rep (2012) 1.31
Construction of regulatory networks using expression time-series data of a genotyped population. Proc Natl Acad Sci U S A (2011) 1.31