Published in Structure on June 01, 2006
Stabilization of RAD-51-DNA filaments via an interaction domain in Caenorhabditis elegans BRCA2. Proc Natl Acad Sci U S A (2007) 1.30
Two modules in the BRC repeats of BRCA2 mediate structural and functional interactions with the RAD51 recombinase. Nucleic Acids Res (2009) 1.21
A human XRCC4-XLF complex bridges DNA. Nucleic Acids Res (2012) 1.15
Structural transitions within human Rad51 nucleoprotein filaments. Proc Natl Acad Sci U S A (2009) 1.06
A novel Fanconi anaemia subtype associated with a dominant-negative mutation in RAD51. Nat Commun (2015) 0.98
Helical filaments of human Dmc1 protein on single-stranded DNA: a cautionary tale. J Mol Biol (2010) 0.96
Structure of the hDmc1-ssDNA filament reveals the principles of its architecture. PLoS One (2010) 0.95
Fission yeast Swi5-Sfr1 protein complex, an activator of Rad51 recombinase, forms an extremely elongated dogleg-shaped structure. J Biol Chem (2011) 0.92
Synergistic action of the Saccharomyces cerevisiae homologous recombination factors Rad54 and Rad51 in chromatin remodeling. DNA Repair (Amst) (2007) 0.91
Biochemistry of eukaryotic homologous recombination. Top Curr Genet (2007) 0.91
Conservation of a conformational switch in RadA recombinase from Methanococcus maripaludis. Acta Crystallogr D Biol Crystallogr (2009) 0.86
Cleavage of bacteriophage lambda cI repressor involves the RecA C-terminal domain. J Mol Biol (2008) 0.85
Assembly-driven activation of the AIM2 foreign-dsDNA sensor provides a polymerization template for downstream ASC. Nat Commun (2015) 0.83
Association of Rad51 polymorphism with DNA repair in BRCA1 mutation carriers and sporadic breast cancer risk. BMC Cancer (2011) 0.83
Monomer networking activates recombinases. Structure (2006) 0.82
Three new structures of left-handed RADA helical filaments: structural flexibility of N-terminal domain is critical for recombinase activity. PLoS One (2009) 0.82
The ATP-mediated regulation of KaiB-KaiC interaction in the cyanobacterial circadian clock. PLoS One (2013) 0.82
Structure of a hexameric form of RadA recombinase from Methanococcus voltae. Acta Crystallogr Sect F Struct Biol Cryst Commun (2012) 0.80
Problems in fitting high resolution structures into electron microscopic reconstructions. HFSP J (2008) 0.80
The RecB nuclease domain binds to RecA-DNA filaments: implications for filament loading. J Mol Biol (2009) 0.78
ATP half-sites in RadA and RAD51 recombinases bind nucleotides. FEBS Open Bio (2016) 0.76
Rad51 inhibition sensitizes breast cancer stem cells to PARP inhibitor in triple-negative breast cancer. Chin J Cancer (2017) 0.76
TP53 Binding to BRCA1 and RAD51 in MCF7 and MDA-MB-468 Breast Cancer Cell Lines In vivo and In vitro. Avicenna J Med Biotechnol (2015) 0.75
pH-dependent activities and structural stability of loop-2-anchoring helix of RadA recombinase from Methanococcus voltae. Protein Pept Lett (2014) 0.75
The Metagenome of Utricularia gibba's Traps: Into the Microbial Input to a Carnivorous Plant. PLoS One (2016) 0.75
Targeting Cell Cycle Proteins in Breast Cancer Cells with siRNA by Using Lipid-Substituted Polyethylenimines. Front Bioeng Biotechnol (2015) 0.75
Structure of a filament of stacked octamers of human DMC1 recombinase. Acta Crystallogr Sect F Struct Biol Cryst Commun (2013) 0.75
Protein splicing of a recombinase intein induced by ssDNA and DNA damage. Genes Dev (2016) 0.75
Cryo-EM structures of human RAD51 recombinase filaments during catalysis of DNA-strand exchange. Nat Struct Mol Biol (2016) 0.75
RadB acts in homologous recombination in the archaeon Haloferax volcanii, consistent with a role as recombination mediator. DNA Repair (Amst) (2017) 0.75
Defects in recombination activity caused by somatic and germline mutations in the multimerization/BRCA2 binding region of human RAD51 protein. DNA Repair (Amst) (2017) 0.75
VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. Nature (2005) 15.57
Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis. Nature (2006) 6.56
Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1. Nat Med (2002) 5.50
IMGT, the international ImMunoGeneTics information system. Nucleic Acids Res (2008) 5.42
Structural basis of membrane invagination by F-BAR domains. Cell (2008) 5.41
Cytokine-mediated deployment of SDF-1 induces revascularization through recruitment of CXCR4+ hemangiocytes. Nat Med (2006) 5.22
Engraftment and reconstitution of hematopoiesis is dependent on VEGFR2-mediated regeneration of sinusoidal endothelial cells. Cell Stem Cell (2009) 4.52
Outcome of the first electron microscopy validation task force meeting. Structure (2012) 4.35
Blocking neuropilin-1 function has an additive effect with anti-VEGF to inhibit tumor growth. Cancer Cell (2007) 4.11
Placental growth factor reconstitutes hematopoiesis by recruiting VEGFR1(+) stem cells from bone-marrow microenvironment. Nat Med (2002) 4.00
PirB is a functional receptor for myelin inhibitors of axonal regeneration. Science (2008) 3.86
Homologous recombination in DNA repair and DNA damage tolerance. Cell Res (2008) 3.86
Alternate pathways involving Sgs1/Top3, Mus81/ Mms4, and Srs2 prevent formation of toxic recombination intermediates from single-stranded gaps created by DNA replication. Proc Natl Acad Sci U S A (2002) 3.70
Complete and specific inhibition of adult lymphatic regeneration by a novel VEGFR-3 neutralizing antibody. J Natl Cancer Inst (2005) 3.58
Stabilization of RAD51 nucleoprotein filaments by the C-terminal region of BRCA2. Nat Struct Mol Biol (2007) 3.45
Type IV pilus structure by cryo-electron microscopy and crystallography: implications for pilus assembly and functions. Mol Cell (2006) 3.36
A specificity map for the PDZ domain family. PLoS Biol (2008) 3.16
Importance of cellular microenvironment and circulatory dynamics in B cell immunotherapy. J Immunol (2005) 3.00
Novel pro- and anti-recombination activities of the Bloom's syndrome helicase. Genes Dev (2007) 2.82
Peritumoral neutrophils link inflammatory response to disease progression by fostering angiogenesis in hepatocellular carcinoma. J Hepatol (2010) 2.71
Limb remote ischemic preconditioning attenuates lung injury after pulmonary resection under propofol-remifentanil anesthesia: a randomized controlled study. Anesthesiology (2014) 2.66
Macroscopic invisibility cloaking of visible light. Nat Commun (2011) 2.61
Atomic model of a myosin filament in the relaxed state. Nature (2005) 2.49
Effects of glucosinolate-rich broccoli sprouts on urinary levels of aflatoxin-DNA adducts and phenanthrene tetraols in a randomized clinical trial in He Zuo township, Qidong, People's Republic of China. Cancer Epidemiol Biomarkers Prev (2005) 2.45
Inhibition of VEGFR-3 activation with the antagonistic antibody more potently suppresses lymph node and distant metastases than inactivation of VEGFR-2. Cancer Res (2006) 2.40
Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA. Nat Struct Mol Biol (2010) 2.37
Rad54, a Swi2/Snf2-like recombinational repair protein, disassembles Rad51:dsDNA filaments. Mol Cell (2002) 2.35
Blocking neuropilin-2 function inhibits tumor cell metastasis. Cancer Cell (2008) 2.35
Expression and function of vascular endothelial growth factor receptor-1 on human colorectal cancer cells. Oncogene (2005) 2.24
The stalk region of dynamin drives the constriction of dynamin tubes. Nat Struct Mol Biol (2004) 2.20
Registry and survival study in chinese patients with idiopathic and familial pulmonary arterial hypertension. Chest (2007) 2.19
Helical structure of the needle of the type III secretion system of Shigella flexneri. J Biol Chem (2003) 2.15
A two-in-one antibody against HER3 and EGFR has superior inhibitory activity compared with monospecific antibodies. Cancer Cell (2011) 2.14
Amelioration of type 2 diabetes by antibody-mediated activation of fibroblast growth factor receptor 1. Sci Transl Med (2011) 2.10
Rad54: the Swiss Army knife of homologous recombination? Nucleic Acids Res (2006) 2.09
Vascular endothelial growth factor receptor-1 activation mediates epithelial to mesenchymal transition in human pancreatic carcinoma cells. Cancer Res (2006) 1.99
The crystal structure of the yeast Hsp40 Ydj1 complexed with its peptide substrate. Structure (2003) 1.97
The persistent circulation of enterovirus 71 in People's Republic of China: causing emerging nationwide epidemics since 2008. PLoS One (2011) 1.96
Structure and disassembly of filaments formed by the ESCRT-III subunit Vps24. Structure (2008) 1.95
Oral hygiene care for critically ill patients to prevent ventilator-associated pneumonia. Cochrane Database Syst Rev (2013) 1.91
Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice. J Clin Invest (2009) 1.89
Structural polymorphism in F-actin. Nat Struct Mol Biol (2010) 1.89
Ectonucleotidases of CD39 family modulate vascular inflammation and thrombosis in transplantation. Semin Thromb Hemost (2005) 1.86
Assembly of Weibel-Palade body-like tubules from N-terminal domains of von Willebrand factor. Proc Natl Acad Sci U S A (2008) 1.81
Nonvascular VEGF receptor 3 expression by corneal epithelium maintains avascularity and vision. Proc Natl Acad Sci U S A (2006) 1.81
ATP-mediated conformational changes in the RecA filament. Structure (2003) 1.79
Processing of joint molecule intermediates by structure-selective endonucleases during homologous recombination in eukaryotes. Chromosoma (2011) 1.78
Effect of molecular therapeutics on liver regeneration in a murine model. J Clin Oncol (2008) 1.76
A therapeutic antibody targeting BACE1 inhibits amyloid-β production in vivo. Sci Transl Med (2011) 1.75
Tumor-derived hyaluronan induces formation of immunosuppressive macrophages through transient early activation of monocytes. Blood (2007) 1.74
Substance abuse vaccines. Ann N Y Acad Sci (2008) 1.74
NADH-coupled microplate photometric assay for kinetic studies of ATP-hydrolyzing enzymes with low and high specific activities. Anal Biochem (2003) 1.74
Halting the interaction between vascular endothelial growth factor and its receptors attenuates liver carcinogenesis in mice. Hepatology (2004) 1.73
Quantitative quality control in microarray experiments and the application in data filtering, normalization and false positive rate prediction. Bioinformatics (2003) 1.73
Neuropilin-1 binds to VEGF121 and regulates endothelial cell migration and sprouting. J Biol Chem (2007) 1.73
Anti-IL-33 antibody treatment inhibits airway inflammation in a murine model of allergic asthma. Biochem Biophys Res Commun (2009) 1.71
A new internal mode in F-actin helps explain the remarkable evolutionary conservation of actin's sequence and structure. Curr Biol (2002) 1.70
Actin-destabilizing factors disrupt filaments by means of a time reversal of polymerization. Proc Natl Acad Sci U S A (2004) 1.70
CD39/ENTPD1 expression by CD4+Foxp3+ regulatory T cells promotes hepatic metastatic tumor growth in mice. Gastroenterology (2010) 1.69
Activated monocytes in peritumoral stroma of hepatocellular carcinoma promote expansion of memory T helper 17 cells. Hepatology (2010) 1.69
ADF/cofilin use an intrinsic mode of F-actin instability to disrupt actin filaments. J Cell Biol (2003) 1.68
BRCA2 BRC motifs bind RAD51-DNA filaments. Proc Natl Acad Sci U S A (2005) 1.68
The structure of bacterial ParM filaments. Nat Struct Mol Biol (2007) 1.66
Crystal structure of archaeal recombinase RADA: a snapshot of its extended conformation. Mol Cell (2004) 1.65
Salutary effects of adiponectin on colon cancer: in vivo and in vitro studies in mice. Gut (2012) 1.65
Vascular endothelial growth factor receptor-1 promotes migration and invasion in pancreatic carcinoma cell lines. Cancer (2005) 1.64
Remodeling of actin filaments by ADF/cofilin proteins. Proc Natl Acad Sci U S A (2011) 1.60
Sublethal heat treatment promotes epithelial-mesenchymal transition and enhances the malignant potential of hepatocellular carcinoma. Hepatology (2013) 1.59
High-resolution cryo-EM structure of the F-actin-fimbrin/plastin ABD2 complex. Proc Natl Acad Sci U S A (2008) 1.59
Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2. Nat Struct Mol Biol (2010) 1.55
Predictive factors of type 2 diabetes mellitus remission following bariatric surgery: a meta-analysis. Obes Surg (2015) 1.55
Filaggrin deficiency confers a paracellular barrier abnormality that reduces inflammatory thresholds to irritants and haptens. J Allergy Clin Immunol (2009) 1.52
PCNA is required for initiation of recombination-associated DNA synthesis by DNA polymerase delta. Mol Cell (2009) 1.52
IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39. Nat Immunol (2013) 1.50
Overexpression of wild-type breast cancer resistance protein mediates methotrexate resistance. Cancer Res (2002) 1.50
Flexibility of the rings: structural asymmetry in the DnaB hexameric helicase. J Mol Biol (2002) 1.48
Targeting autocrine and paracrine VEGF receptor pathways inhibits human lymphoma xenografts in vivo. Blood (2004) 1.46
Divergence of quaternary structures among bacterial flagellar filaments. Science (2008) 1.46
A comparative analysis of Dmc1 and Rad51 nucleoprotein filaments. Nucleic Acids Res (2008) 1.46
Risk factors for predicting postoperative complications after open infrarenal abdominal aortic aneurysm repair: results from a single vascular center in China. J Clin Anesth (2013) 1.46
Selective targeting of angiogenic tumor vasculature by vascular endothelial-cadherin antibody inhibits tumor growth without affecting vascular permeability. Cancer Res (2002) 1.45
Saccharomyces cerevisiae Mus81-Mms4 is a catalytic, DNA structure-selective endonuclease. Nucleic Acids Res (2008) 1.44
Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding. EMBO J (2007) 1.43
Trends in red blood cell transfusion and 30-day mortality among hospitalized patients. Transfusion (2014) 1.43
Urodynamic investigation of cyclophosphamide-induced overactive bladder in conscious rats. Chin Med J (Engl) (2012) 1.42
A pilot study of intense pulsed light in the treatment of Riehl's melanosis. Dermatol Surg (2010) 1.42
Helicity in electron microscopy images-a comment on Wang TF, Chen LT and Wang AH 2008 BioEssays 30:48-56. Bioessays (2008) 1.41
The crystal structures of yeast Get3 suggest a mechanism for tail-anchored protein membrane insertion. PLoS One (2009) 1.39
Mapping the cellular response to small molecules using chemogenomic fitness signatures. Science (2014) 1.39