Published in Am J Physiol Heart Circ Physiol on July 01, 2006
Molecular Mechanisms of Mitral Regurgitation—Aim 2 (P1A2) | NCT01052532
A randomized controlled phase IIb trial of beta(1)-receptor blockade for chronic degenerative mitral regurgitation. J Am Coll Cardiol (2012) 1.69
Cardiac innervation and sudden cardiac death. Circ Res (2015) 1.29
Sympathetic activation causes focal adhesion signaling alteration in early compensated volume overload attributable to isolated mitral regurgitation in the dog. Circ Res (2008) 1.07
Dissociation between cardiomyocyte function and remodeling with beta-adrenergic receptor blockade in isolated canine mitral regurgitation. Am J Physiol Heart Circ Physiol (2008) 1.05
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Increased sarcolipin expression and adrenergic drive in humans with preserved left ventricular ejection fraction and chronic isolated mitral regurgitation. Circ Heart Fail (2013) 0.87
Remodeling of intrinsic cardiac neurons: effects of β-adrenergic receptor blockade in guinea pig models of chronic heart disease. Am J Physiol Regul Integr Comp Physiol (2012) 0.86
Activated cranial cervical cord neurons affect left ventricular infarct size and the potential for sudden cardiac death. Auton Neurosci (2012) 0.81
Vagus nerve stimulation mitigates intrinsic cardiac neuronal and adverse myocyte remodeling postmyocardial infarction. Am J Physiol Heart Circ Physiol (2015) 0.81
Chronic β1-adrenergic blockade enhances myocardial β3-adrenergic coupling with nitric oxide-cGMP signaling in a canine model of chronic volume overload: new insight into mechanisms of cardiac benefit with selective β1-blocker therapy. Basic Res Cardiol (2014) 0.79
The multiple mechanistic faces of a pure volume overload: implications for therapy. Am J Med Sci (2014) 0.78
Volume overload induces autophagic degradation of procollagen in cardiac fibroblasts. J Mol Cell Cardiol (2015) 0.77
Desmin Loss and Mitochondrial Damage Precede Left Ventricular Systolic Failure in Volume Overload Heart Failure. Am J Physiol Heart Circ Physiol (2017) 0.75
Heart failure, chronic diuretic use, and increase in mortality and hospitalization: an observational study using propensity score methods. Eur Heart J (2006) 4.55
Effects of dietary sodium reduction on blood pressure in subjects with resistant hypertension: results from a randomized trial. Hypertension (2009) 4.26
Valganciclovir for symptomatic congenital cytomegalovirus disease. N Engl J Med (2015) 3.75
Magnetic resonance imaging with 3-dimensional analysis of left ventricular remodeling in isolated mitral regurgitation: implications beyond dimensions. Circulation (2012) 2.37
Left ventricular eccentric remodeling and matrix loss are mediated by bradykinin and precede cardiomyocyte elongation in rats with volume overload. J Am Coll Cardiol (2007) 2.21
Refractory hypertension: definition, prevalence, and patient characteristics. J Clin Hypertens (Greenwich) (2011) 2.11
Capacitative calcium entry contributes to nuclear factor of activated T-cells nuclear translocation and hypertrophy in cardiomyocytes. J Biol Chem (2002) 1.89
Isolated systolic hypertension and incident heart failure in older adults: a propensity-matched study. Hypertension (2009) 1.88
Rapid reversal of left ventricular hypertrophy and intracardiac volume overload in patients with resistant hypertension and hyperaldosteronism: a prospective clinical study. Hypertension (2010) 1.85
Apocynin attenuates tubular apoptosis and tubulointerstitial fibrosis in transgenic mice independent of hypertension. Kidney Int (2008) 1.78
Effects of right ventricular ejection fraction on outcomes in chronic systolic heart failure. Circulation (2010) 1.73
A randomized controlled phase IIb trial of beta(1)-receptor blockade for chronic degenerative mitral regurgitation. J Am Coll Cardiol (2012) 1.69
Characterization of resistant hypertension: association between resistant hypertension, aldosterone, and persistent intravascular volume expansion. Arch Intern Med (2008) 1.68
Angiotensin II receptor blockade does not improve left ventricular function and remodeling in subacute mitral regurgitation in the dog. J Am Coll Cardiol (2002) 1.65
c-kit is required for cardiomyocyte terminal differentiation. Circ Res (2008) 1.58
Attenuation of interstitial fibrosis and tubular apoptosis in db/db transgenic mice overexpressing catalase in renal proximal tubular cells. Diabetes (2007) 1.57
Absence of obesity paradox in patients with chronic heart failure and diabetes mellitus: a propensity-matched study. Eur J Heart Fail (2010) 1.55
Increased oxidative stress and cardiomyocyte myofibrillar degeneration in patients with chronic isolated mitral regurgitation and ejection fraction >60%. J Am Coll Cardiol (2010) 1.52
Routine, self-administered, touch-screen, computer-based suicidal ideation assessment linked to automated response team notification in an HIV primary care setting. Clin Infect Dis (2010) 1.51
Relative efficiency and sample size for cluster randomized trials with variable cluster sizes. Clin Trials (2010) 1.50
A propensity-matched study of the effect of diabetes on the natural history of heart failure: variations by sex and age. Heart (2007) 1.46
Evaluation of a new in-clinic method for the detection of canine heartworm antigen. Vet Parasitol (2010) 1.46
Automated multidetector computed tomography evaluation of subacutely infarcted myocardium. J Cardiovasc Comput Tomogr (2007) 1.41
Microarray identifies extensive downregulation of noncollagen extracellular matrix and profibrotic growth factor genes in chronic isolated mitral regurgitation in the dog. Circulation (2009) 1.39
Tachykinin agonists modulate cholinergic neurotransmission at guinea-pig intracardiac Ganglia. J Pharmacol Sci (2005) 1.38
Mechanism of allosteric regulation of transglutaminase 2 by GTP. Proc Natl Acad Sci U S A (2006) 1.38
Association between hyperuricemia and incident heart failure among older adults: a propensity-matched study. Int J Cardiol (2009) 1.38
A history of atrial fibrillation and outcomes in chronic advanced systolic heart failure: a propensity-matched study. Eur Heart J (2009) 1.34
Cardiac mast cell- and chymase-mediated matrix metalloproteinase activity and left ventricular remodeling in mitral regurgitation in the dog. J Mol Cell Cardiol (2003) 1.32
A dual propagation contours technique for semi-automated assessment of systolic and diastolic cardiac function by CMR. J Cardiovasc Magn Reson (2009) 1.29
Protection from adverse myocardial remodeling secondary to chronic volume overload in mast cell deficient rats. J Mol Cell Cardiol (2008) 1.27
Mast cell chymase limits the cardiac efficacy of Ang I-converting enzyme inhibitor therapy in rodents. J Clin Invest (2010) 1.26
A propensity-matched study of elevated jugular venous pressure and outcomes in chronic heart failure. Am J Cardiol (2009) 1.24
Overexpression of angiotensinogen increases tubular apoptosis in diabetes. J Am Soc Nephrol (2007) 1.22
Renin-angiotensin inhibition in systolic heart failure and chronic kidney disease. Am J Med (2012) 1.22
A thrombospondin-1 antagonist of transforming growth factor-beta activation blocks cardiomyopathy in rats with diabetes and elevated angiotensin II. Am J Pathol (2007) 1.20
Activation of the hexosamine biosynthesis pathway and protein O-GlcNAcylation modulate hypertrophic and cell signaling pathways in cardiomyocytes from diabetic mice. Amino Acids (2010) 1.20
Relation of baseline systolic blood pressure and long-term outcomes in ambulatory patients with chronic mild to moderate heart failure. Am J Cardiol (2011) 1.19
Differential genomic responses in old vs. young humans despite similar levels of modest muscle damage after resistance loading. Physiol Genomics (2009) 1.18
Involvement of chymase-mediated angiotensin II generation in blood pressure regulation. J Clin Invest (2004) 1.18
Changes in lipoproteins associated with methotrexate or combination therapy in early rheumatoid arthritis: results from the treatment of early rheumatoid arthritis trial. Arthritis Rheum (2013) 1.18
Network interactions within the canine intrinsic cardiac nervous system: implications for reflex control of regional cardiac function. J Physiol (2013) 1.17
Relation of dietary salt and aldosterone to urinary protein excretion in subjects with resistant hypertension. Hypertension (2007) 1.14
Beta1-adrenergic receptor blockade attenuates angiotensin II-mediated catecholamine release into the cardiac interstitium in mitral regurgitation. Circulation (2003) 1.11
Inflammation, oxidation and venous neointimal hyperplasia precede vascular injury from AVF creation in CKD patients. J Vasc Access (2012) 1.09
Status of the thymectomy trial for nonthymomatous myasthenia gravis patients receiving prednisone. Ann N Y Acad Sci (2008) 1.08
Impact of baseline systolic blood pressure on long-term outcomes in patients with advanced chronic systolic heart failure (insights from the BEST trial). Am J Cardiol (2010) 1.08
Cardiac kallikrein-kinin system is upregulated in chronic volume overload and mediates an inflammatory induced collagen loss. PLoS One (2012) 1.08
Dynamic molecular and histopathological changes in the extracellular matrix and inflammation in the transition to heart failure in isolated volume overload. Am J Physiol Heart Circ Physiol (2011) 1.07
Sympathetic activation causes focal adhesion signaling alteration in early compensated volume overload attributable to isolated mitral regurgitation in the dog. Circ Res (2008) 1.07
Neurally released pituitary adenylate cyclase-activating polypeptide enhances guinea pig intrinsic cardiac neurone excitability. J Physiol (2007) 1.05
Interactions within the intrinsic cardiac nervous system contribute to chronotropic regulation. Am J Physiol Regul Integr Comp Physiol (2003) 1.05
Dissociation between cardiomyocyte function and remodeling with beta-adrenergic receptor blockade in isolated canine mitral regurgitation. Am J Physiol Heart Circ Physiol (2008) 1.05
Dorsal spinal cord stimulation obtunds the capacity of intrathoracic extracardiac neurons to transduce myocardial ischemia. Am J Physiol Regul Integr Comp Physiol (2009) 1.04
Patient reported outcomes in routine care: advancing data capture for HIV cohort research. Clin Infect Dis (2011) 1.04
Dissecting the role of chymase in angiotensin II formation and heart and blood vessel diseases. Curr Opin Cardiol (2002) 1.04
Reactive oxygen species blockade and action of insulin on expression of angiotensinogen gene in proximal tubular cells. J Endocrinol (2004) 1.04
A despecialization step underlying evolution of a family of serine proteases. Mol Cell (2003) 1.03
Darunavir outcomes study: comparative effectiveness of virologic suppression, regimen durability, and discontinuation reasons for three-class experienced patients at 48 weeks. AIDS Res Hum Retroviruses (2010) 1.03
Increased plasma chymase concentration and mast cell chymase expression in venous neointimal lesions of patients with CKD and ESRD. Semin Dial (2011) 1.02
Mild hyperkalemia and outcomes in chronic heart failure: a propensity matched study. Int J Cardiol (2009) 1.01
Autonomic Regulation Therapy in Heart Failure. Curr Heart Fail Rep (2015) 1.01
Spinal cord stimulation suppresses bradycardias and atrial tachyarrhythmias induced by mediastinal nerve stimulation in dogs. Am J Physiol Regul Integr Comp Physiol (2006) 1.01
GTP cyclohydrolase I phosphorylation and interaction with GTP cyclohydrolase feedback regulatory protein provide novel regulation of endothelial tetrahydrobiopterin and nitric oxide. Circ Res (2009) 1.00
Alpha-adrenoceptor blockade modifies neurally induced atrial arrhythmias. Am J Physiol Regul Integr Comp Physiol (2008) 1.00
Mitochondrial genetic background modulates bioenergetics and susceptibility to acute cardiac volume overload. Biochem J (2013) 0.99
Calcitonin gene-related peptide in vivo positive inotropy is attributable to regional sympatho-stimulation and is blunted in congestive heart failure. Circ Res (2004) 0.99
Remodeling of cardiac cholinergic innervation and control of heart rate in mice with streptozotocin-induced diabetes. Auton Neurosci (2011) 0.99
Experimental avoidance as a mediator of the effects of adolescent sexual victimization on negative adult outcomes. Violence Vict (2004) 0.99
Spatially divergent cardiac responses to nicotinic stimulation of ganglionated plexus neurons in the canine heart. Auton Neurosci (2008) 0.98
Parasympathetic control of the heart. II. A novel interganglionic intrinsic cardiac circuit mediates neural control of heart rate. J Appl Physiol (1985) (2004) 0.98
Short-acting beta-adrenergic antagonist esmolol given at reperfusion improves survival after prolonged ventricular fibrillation. Circulation (2004) 0.97