Published in JAMA on July 12, 2006
Short-course Out-patient Pulmonary Rehabilitation and COPD Exacerbations | NCT02471235
Short sleep duration and weight gain: a systematic review. Obesity (Silver Spring) (2008) 7.40
A systematic review of the evidence for Canada's Physical Activity Guidelines for Adults. Int J Behav Nutr Phys Act (2010) 4.05
Amount of time spent in sedentary behaviors and cause-specific mortality in US adults. Am J Clin Nutr (2012) 3.95
Why is late-life disability declining? Milbank Q (2008) 2.81
Barriers to self-management and quality-of-life outcomes in seniors with multimorbidities. Ann Fam Med (2007) 2.37
Leisure-time physical activity and all-cause mortality in an elderly cohort. Epidemiology (2009) 2.29
Activity energy expenditure and incident cognitive impairment in older adults. Arch Intern Med (2011) 2.07
Low-intensity physical activity is associated with reduced risk of incident type 2 diabetes in older adults: evidence from the English Longitudinal Study of Ageing. Diabetologia (2010) 1.91
Improving self-reports of active and sedentary behaviors in large epidemiologic studies. Exerc Sport Sci Rev (2012) 1.75
Use of accelerometry to measure physical activity in older adults at risk for mobility disability. J Aging Phys Act (2008) 1.73
Validation of an armband to measure daily energy expenditure in older adults. J Gerontol A Biol Sci Med Sci (2011) 1.56
Assessment of wear/nonwear time classification algorithms for triaxial accelerometer. Med Sci Sports Exerc (2012) 1.54
Patterns of ambulatory activity in subjects with and without intermittent claudication. J Vasc Surg (2007) 1.47
Comparing the 7-day physical activity recall with a triaxial accelerometer for measuring time in exercise. Med Sci Sports Exerc (2009) 1.41
Taking up physical activity in later life and healthy ageing: the English longitudinal study of ageing. Br J Sports Med (2013) 1.39
Intrinsic aerobic capacity sets a divide for aging and longevity. Circ Res (2011) 1.33
Light-intensity activities are important for estimating physical activity energy expenditure using uniaxial and triaxial accelerometers. Eur J Appl Physiol (2008) 1.29
Energy expenditure does not predict weight change in either Nigerian or African American women. Am J Clin Nutr (2008) 1.24
Everyday physical activity as a predictor of late-life mortality. Gerontologist (2008) 1.24
Changes in cognition and mortality in relation to exercise in late life: a population based study. PLoS One (2008) 1.22
8-Oxo-7,8-dihydroguanine: links to gene expression, aging, and defense against oxidative stress. Free Radic Biol Med (2010) 1.20
Depressive symptoms, physical inactivity and risk of cardiovascular mortality in older adults: the Cardiovascular Health Study. Heart (2011) 1.19
Physical activity in obesity and metabolic syndrome. Ann N Y Acad Sci (2012) 1.16
Experience and management of chronic pain among patients with other complex chronic conditions. Clin J Pain (2009) 1.14
Adverse events among high-risk participants in a home-based walking study: a descriptive study. Int J Behav Nutr Phys Act (2007) 1.11
Recommendations for standardizing validation procedures assessing physical activity of older persons by monitoring body postures and movements. Sensors (Basel) (2014) 1.09
Activity energy expenditure and change in body composition in late life. Am J Clin Nutr (2009) 1.09
Associations of objectively assessed physical activity and sedentary time with all-cause mortality in US adults: the NHANES study. PLoS One (2015) 1.09
Maintaining physical activity among older adults: six-month outcomes of the Keep Active Minnesota randomized controlled trial. Prev Med (2007) 1.08
Energy expenditure and aging. Ageing Res Rev (2009) 1.05
Associations of sitting behaviours with all-cause mortality over a 16-year follow-up: the Whitehall II study. Int J Epidemiol (2015) 1.04
Energy expenditure in adults living in developing compared with industrialized countries: a meta-analysis of doubly labeled water studies. Am J Clin Nutr (2010) 1.04
Combined impact of traditional and non-traditional health behaviors on mortality: a national prospective cohort study in Spanish older adults. BMC Med (2013) 1.04
Levels of physical activity among a nationally representative sample of people in early old age: results of objective and self-reported assessments. Int J Behav Nutr Phys Act (2014) 1.03
Impact of exercise in community-dwelling older adults. PLoS One (2009) 1.03
Effect of exercise and calorie restriction on biomarkers of aging in mice. Am J Physiol Regul Integr Comp Physiol (2008) 1.03
The effects of daily weather on accelerometer-measured physical activity. J Phys Act Health (2011) 1.03
Activity energy expenditure and mobility limitation in older adults: differential associations by sex. Am J Epidemiol (2009) 1.02
Dietary factors in relation to daily activity energy expenditure and mortality among older adults. J Nutr Health Aging (2009) 1.02
Physical activity is a predictor of all-cause mortality in patients with intermittent claudication. J Vasc Surg (2008) 1.01
Objectively measured physical activity and mortality in older adults. JAMA (2006) 1.00
Mitohormesis: Promoting Health and Lifespan by Increased Levels of Reactive Oxygen Species (ROS). Dose Response (2014) 1.00
Mortality Benefits for Replacing Sitting Time with Different Physical Activities. Med Sci Sports Exerc (2015) 0.99
Association between lifestyle and physical activity level in the elderly: a study using doubly labeled water and simplified physical activity record. Eur J Appl Physiol (2013) 0.96
Objective measures of activity level and mortality in older men. J Am Geriatr Soc (2014) 0.96
Physical activity and older adults: expert consensus for a new research agenda. Gerontologist (2011) 0.96
Influence of life course socioeconomic position on older women's health behaviors: findings from the British Women's Heart and Health Study. Am J Public Health (2008) 0.94
Long-term voluntary exercise, representing habitual exercise, lowers visceral fat and alters plasma amino acid levels in mice. Environ Health Prev Med (2011) 0.93
Functional performance in community-dwelling and institutionalized elderly women. Wien Klin Wochenschr (2009) 0.92
Fat or fit: what is more important? Diabetes Care (2009) 0.92
Effect of a nutrition supplement and physical activity program on pneumonia and walking capacity in Chilean older people: a factorial cluster randomized trial. PLoS Med (2011) 0.92
Activity monitoring in chronic obstructive pulmonary disease. J Cardiopulm Rehabil Prev (2009) 0.91
Predicting daily physical activity in patients with chronic obstructive pulmonary disease. PLoS One (2012) 0.91
Referral from primary care to a physical activity programme: establishing long-term adherence? A randomized controlled trial. Rationale and study design. BMC Public Health (2009) 0.90
Age, affective experience, and television use. Am J Prev Med (2010) 0.90
Estimating energy expenditure from heart rate in older adults: a case for calibration. PLoS One (2014) 0.90
Recreational physical activity in postmenopausal women is stable over 8 years of follow-up. J Phys Act Health (2012) 0.89
Mitochondrial-nuclear epistasis: implications for human aging and longevity. Ageing Res Rev (2010) 0.89
Television viewing, computer use, time driving and all-cause mortality: the SUN cohort. J Am Heart Assoc (2014) 0.88
Total daily activity measured with actigraphy and motor function in community-dwelling older persons with and without dementia. Alzheimer Dis Assoc Disord (2012) 0.87
Non-leisure time physical activity is an independent predictor of longevity for a Taiwanese elderly population: an eight-year follow-up study. BMC Public Health (2011) 0.86
Physical activity and years of healthy life in older adults: results from the cardiovascular health study. J Aging Phys Act (2010) 0.86
Pilot study: can older inactive adults learn how to reach the required intensity of physical activity guideline? Clin Interv Aging (2013) 0.85
Effects of an 8-month exercise training program on off-exercise physical activity. Med Sci Sports Exerc (2011) 0.85
Determinants of gait speed in COPD. Chest (2014) 0.83
Health Coaching and Chronic Obstructive Pulmonary Disease Rehospitalization. A Randomized Study. Am J Respir Crit Care Med (2016) 0.82
Diabetes family history: a metabolic storm you should not sit out. Diabetes (2010) 0.82
Leisure-time physical activity, cardiovascular risk factors and mortality during a 34-year follow-up in men. Eur J Epidemiol (2010) 0.81
Serum lipid profiles and cancer risk in the context of obesity: four meta-analyses. J Cancer Epidemiol (2013) 0.81
Mitochondrial DNA sequence variation associated with dementia and cognitive function in the elderly. J Alzheimers Dis (2012) 0.81
Housework reduces all-cause and cancer mortality in Chinese men. PLoS One (2013) 0.81
Physical activity in non-frail and frail older adults. PLoS One (2015) 0.81
Accuracy of a combined heart rate and motion sensor for assessing energy expenditure in free-living adults during a double-blind crossover caffeine trial using doubly labeled water as the reference method. Eur J Clin Nutr (2014) 0.80
Changing behavioral patterns to promote physical activity with motivational signs. Environ Health Prev Med (2008) 0.80
Intensity of physical activity in the energy expenditure of older adults. J Aging Phys Act (2013) 0.80
Designing Phase II B trials in sarcopenia: the best target population. J Nutr Health Aging (2011) 0.80
Patterns and correlates of objectively measured free-living physical activity in adults in rural and urban Cameroon. J Epidemiol Community Health (2015) 0.80
Life-space mobility and mortality in older men: a prospective cohort study. J Am Geriatr Soc (2014) 0.80
Potential for intensive volunteering to promote the health of older adults in fair health. J Urban Health (2009) 0.80
Validation of Web-based physical activity measurement systems using doubly labeled water. J Med Internet Res (2012) 0.80
Pathways to aging: the mitochondrion at the intersection of biological and psychosocial sciences. J Aging Res (2011) 0.80
Impact of pain characteristics and fear-avoidance beliefs on physical activity levels among older adults with chronic pain: a population-based, longitudinal study. BMC Geriatr (2016) 0.79
European ancestry and resting metabolic rate in older African Americans. Eur J Clin Nutr (2011) 0.79
[Measurement of physical activity in older adults. Correlation between the PRISCUS-PAQ and accelerometry]. Z Gerontol Geriatr (2012) 0.79
Arterial elasticity in American Indian and Caucasian children, adolescents, and young adults. Vasc Med (2011) 0.79
Mitochondrial DNA sequence variation is associated with free-living activity energy expenditure in the elderly. Biochim Biophys Acta (2012) 0.79
Physical activity in older age: perspectives for healthy ageing and frailty. Biogerontology (2016) 0.79
Examining Non-Linear Associations between Accelerometer-Measured Physical Activity, Sedentary Behavior, and All-Cause Mortality Using Segmented Cox Regression. Front Physiol (2016) 0.79
Physical inactivity and arterial stiffness in COPD. Int J Chron Obstruct Pulmon Dis (2015) 0.78
Evaluation of physical activity programmes for the elderly - exploring the lessons from other sectors and examining the general characteristics of the programmes. BMC Res Notes (2011) 0.78
Physical activity and the pelvic floor. Am J Obstet Gynecol (2015) 0.78
State variations of chronic disease risk factors in older Americans. Prev Chronic Dis (2012) 0.78
Physical activity and the frequency of acute exacerbations in patients with chronic obstructive pulmonary disease. Lung (2014) 0.78
Physical activity and all-cause mortality among older Brazilian adults: 11-year follow-up of the Bambuí Health and Aging Study. Clin Interv Aging (2015) 0.77
Associations of Accelerometry-Assessed and Self-Reported Physical Activity and Sedentary Behavior With All-Cause and Cardiovascular Mortality Among US Adults. Am J Epidemiol (2016) 0.77
Sestrin2, a Regulator of Thermogenesis and Mitohormesis in Brown Adipose Tissue. Front Endocrinol (Lausanne) (2015) 0.76
Cost-effectiveness of a symptom management intervention: improving physical activity in older women following coronary artery bypass surgery. Nurs Econ (2012) 0.76
Primary prevention of heart failure. ISRN Cardiol (2012) 0.76
The relationship between academic performance and recreation use among first-year medical students. Med Educ Online (2015) 0.76
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
Overweight, obesity, and mortality in a large prospective cohort of persons 50 to 71 years old. N Engl J Med (2006) 16.17
Gait speed and survival in older adults. JAMA (2011) 15.01
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Effects of continuing or stopping alendronate after 5 years of treatment: the Fracture Intervention Trial Long-term Extension (FLEX): a randomized trial. JAMA (2006) 12.47
Genome-wide association study of blood pressure and hypertension. Nat Genet (2009) 11.54
Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA (2010) 9.52
Prolonged therapy of advanced chronic hepatitis C with low-dose peginterferon. N Engl J Med (2008) 9.33
Common genetic determinants of vitamin D insufficiency: a genome-wide association study. Lancet (2010) 8.89
Expending our physical activity (measurement) budget wisely. J Appl Physiol (1985) (2011) 8.49
Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium: Design of prospective meta-analyses of genome-wide association studies from 5 cohorts. Circ Cardiovasc Genet (2009) 8.42
Structure of dietary measurement error: results of the OPEN biomarker study. Am J Epidemiol (2003) 8.25
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
Using intake biomarkers to evaluate the extent of dietary misreporting in a large sample of adults: the OPEN study. Am J Epidemiol (2003) 7.68
The loss of skeletal muscle strength, mass, and quality in older adults: the health, aging and body composition study. J Gerontol A Biol Sci Med Sci (2006) 7.38
Dietary and supplemental calcium intake and cardiovascular disease mortality: the National Institutes of Health-AARP diet and health study. JAMA Intern Med (2013) 7.30
Association of long-distance corridor walk performance with mortality, cardiovascular disease, mobility limitation, and disability. JAMA (2006) 6.93
The burden of selected digestive diseases in the United States. Gastroenterology (2002) 6.79
Prognostic value of usual gait speed in well-functioning older people--results from the Health, Aging and Body Composition Study. J Am Geriatr Soc (2005) 6.54
Bisphosphonates and fractures of the subtrochanteric or diaphyseal femur. N Engl J Med (2010) 6.47
Muscle mass, muscle strength, and muscle fat infiltration as predictors of incident mobility limitations in well-functioning older persons. J Gerontol A Biol Sci Med Sci (2005) 6.42
Intra-individual change over time in DNA methylation with familial clustering. JAMA (2008) 6.17
Strength, but not muscle mass, is associated with mortality in the health, aging and body composition study cohort. J Gerontol A Biol Sci Med Sci (2006) 6.08
Diabetes increases the risk of chronic liver disease and hepatocellular carcinoma. Gastroenterology (2004) 5.83
New loci associated with kidney function and chronic kidney disease. Nat Genet (2010) 5.58
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet (2012) 5.48
Association of plasma beta-amyloid level and cognitive reserve with subsequent cognitive decline. JAMA (2011) 5.21
Subclinical hypothyroidism and the risk of coronary heart disease and mortality. JAMA (2010) 5.20
Comparisons of percentage body fat, body mass index, waist circumference, and waist-stature ratio in adults. Am J Clin Nutr (2008) 5.01
High-trauma fractures and low bone mineral density in older women and men. JAMA (2007) 5.00
Determinants of the association of overweight with elevated serum alanine aminotransferase activity in the United States. Gastroenterology (2003) 4.95
Des-gamma-carboxy prothrombin and alpha-fetoprotein as biomarkers for the early detection of hepatocellular carcinoma. Gastroenterology (2009) 4.90
Multiple loci associated with indices of renal function and chronic kidney disease. Nat Genet (2009) 4.78
The prevalence of celiac disease in the United States. Am J Gastroenterol (2012) 4.77
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet (2012) 4.73
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science (2013) 4.71
Inflammatory markers and onset of cardiovascular events: results from the Health ABC study. Circulation (2003) 4.67
Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies. Lancet (2012) 4.63
Leg muscle mass and composition in relation to lower extremity performance in men and women aged 70 to 79: the health, aging and body composition study. J Am Geriatr Soc (2002) 4.55
A comparison of a food frequency questionnaire with a 24-hour recall for use in an epidemiological cohort study: results from the biomarker-based Observing Protein and Energy Nutrition (OPEN) study. Int J Epidemiol (2003) 4.39
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nat Genet (2012) 4.37
Sleep curtailment is accompanied by increased intake of calories from snacks. Am J Clin Nutr (2008) 4.33
Deficiency of subsarcolemmal mitochondria in obesity and type 2 diabetes. Diabetes (2005) 4.31
Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. Nat Genet (2009) 4.28
Peginterferon alfa-2a and ribavirin in patients with chronic hepatitis C who have failed prior treatment. Gastroenterology (2004) 4.27
Hearing loss and cognitive decline in older adults. JAMA Intern Med (2013) 4.25
Association between regional adipose tissue distribution and both type 2 diabetes and impaired glucose tolerance in elderly men and women. Diabetes Care (2003) 4.23
Obesity, regional body fat distribution, and the metabolic syndrome in older men and women. Arch Intern Med (2005) 4.11
Sarcopenia: alternative definitions and associations with lower extremity function. J Am Geriatr Soc (2003) 4.02
Relationship of interleukin-6 and tumor necrosis factor-alpha with muscle mass and muscle strength in elderly men and women: the Health ABC Study. J Gerontol A Biol Sci Med Sci (2002) 4.00
Common variants in KCNN3 are associated with lone atrial fibrillation. Nat Genet (2010) 3.97
Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children. PLoS Med (2011) 3.94
Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits. PLoS Genet (2011) 3.92
Personalized epigenomic signatures that are stable over time and covary with body mass index. Sci Transl Med (2010) 3.81
Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry. Nat Genet (2009) 3.80
Genome-wide association study of PR interval. Nat Genet (2010) 3.73
Meta-analysis identifies six new susceptibility loci for atrial fibrillation. Nat Genet (2012) 3.71
Therapy modifications in response to poorly controlled hypertension, dyslipidemia, and diabetes mellitus. Ann Intern Med (2006) 3.71
Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. Circulation (2011) 3.68
Association of plasma leptin levels with incident Alzheimer disease and MRI measures of brain aging. JAMA (2009) 3.62
Cognitive function, gait speed decline, and comorbidities: the health, aging and body composition study. J Gerontol A Biol Sci Med Sci (2007) 3.61
Reduced neutrophil count in people of African descent is due to a regulatory variant in the Duffy antigen receptor for chemokines gene. PLoS Genet (2009) 3.60
Subclinical hypothyroidism and the risk of heart failure, other cardiovascular events, and death. Arch Intern Med (2005) 3.56
Estimating the changes in energy flux that characterize the rise in obesity prevalence. Am J Clin Nutr (2009) 3.56
Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction. Nat Genet (2010) 3.55
Cytokines, insulin-like growth factor 1, sarcopenia, and mortality in very old community-dwelling men and women: the Framingham Heart Study. Am J Med (2003) 3.54
Sarcopenic obesity: definition, cause and consequences. Curr Opin Clin Nutr Metab Care (2008) 3.54
Limited literacy and mortality in the elderly: the health, aging, and body composition study. J Gen Intern Med (2006) 3.51
Coffee intake is associated with lower rates of liver disease progression in chronic hepatitis C. Hepatology (2009) 3.50
Evolution of the HALT-C Trial: pegylated interferon as maintenance therapy for chronic hepatitis C in previous interferon nonresponders. Control Clin Trials (2004) 3.46
Longitudinal study of muscle strength, quality, and adipose tissue infiltration. Am J Clin Nutr (2009) 3.44
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet (2011) 3.40
Adipose tissue in muscle: a novel depot similar in size to visceral adipose tissue. Am J Clin Nutr (2005) 3.40
Nontraumatic fracture risk with diabetes mellitus and impaired fasting glucose in older white and black adults: the health, aging, and body composition study. Arch Intern Med (2005) 3.39
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet (2010) 3.37
Adiposity in relation to vitamin D status and parathyroid hormone levels: a population-based study in older men and women. J Clin Endocrinol Metab (2005) 3.36
Genetic ancestry in lung-function predictions. N Engl J Med (2010) 3.30
Association between hypoglycemia and dementia in a biracial cohort of older adults with diabetes mellitus. JAMA Intern Med (2013) 3.25
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet (2013) 3.25
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
Change in muscle strength explains accelerated decline of physical function in older women with high interleukin-6 serum levels. J Am Geriatr Soc (2002) 3.21