Published in Cell on August 10, 2006
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iPS cells produce viable mice through tetraploid complementation. Nature (2009) 6.51
Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells. Hepatology (2010) 6.40
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Direct conversion of human fibroblasts to multilineage blood progenitors. Nature (2010) 5.35
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Generation of germline-competent induced pluripotent stem cells. Nature (2007) 32.77
Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat Biotechnol (2007) 21.93
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Generation of mouse induced pluripotent stem cells without viral vectors. Science (2008) 15.25
Generation of pluripotent stem cells from adult mouse liver and stomach cells. Science (2008) 10.55
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Variation in the safety of induced pluripotent stem cell lines. Nat Biotechnol (2009) 6.39
Hypoxia enhances the generation of induced pluripotent stem cells. Cell Stem Cell (2009) 4.38
Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage. Nat Biotechnol (2011) 3.97
mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells. Mol Cell Biol (2004) 3.72
Reactivation of the paternal X chromosome in early mouse embryos. Science (2004) 3.59
Directed and systematic differentiation of cardiovascular cells from mouse induced pluripotent stem cells. Circulation (2008) 3.11
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells. Nature (2003) 3.08
Broader implications of defining standards for the pluripotency of iPSCs. Cell Stem Cell (2009) 3.03
Drug screening for ALS using patient-specific induced pluripotent stem cells. Sci Transl Med (2012) 2.80
Generation of retinal cells from mouse and human induced pluripotent stem cells. Neurosci Lett (2009) 2.75
Therapeutic potential of appropriately evaluated safe-induced pluripotent stem cells for spinal cord injury. Proc Natl Acad Sci U S A (2010) 2.52
Transcriptional repression and DNA hypermethylation of a small set of ES cell marker genes in male germline stem cells. BMC Dev Biol (2006) 2.50
Distinct signaling events downstream of mTOR cooperate to mediate the effects of amino acids and insulin on initiation factor 4E-binding proteins. Mol Cell Biol (2005) 2.47
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Modeling Alzheimer's disease with iPSCs reveals stress phenotypes associated with intracellular Aβ and differential drug responsiveness. Cell Stem Cell (2013) 2.32
Modeling familial Alzheimer's disease with induced pluripotent stem cells. Hum Mol Genet (2011) 2.26
An efficient nonviral method to generate integration-free human-induced pluripotent stem cells from cord blood and peripheral blood cells. Stem Cells (2013) 2.18
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Grafted human-induced pluripotent stem-cell-derived neurospheres promote motor functional recovery after spinal cord injury in mice. Proc Natl Acad Sci U S A (2011) 2.09
Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells. J Exp Med (2010) 2.08
Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability. Proc Natl Acad Sci U S A (2009) 2.00
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Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture. Dis Model Mech (2011) 1.87
Steps toward safe cell therapy using induced pluripotent stem cells. Circ Res (2013) 1.80
Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells. Proc Natl Acad Sci U S A (2012) 1.78
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Complete genetic correction of ips cells from Duchenne muscular dystrophy. Mol Ther (2009) 1.74
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Induced pluripotent stem cell-derived hepatocytes have the functional and proliferative capabilities needed for liver regeneration in mice. J Clin Invest (2010) 1.66
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Differential membrane localization of ERas and Rheb, two Ras-related proteins involved in the phosphatidylinositol 3-kinase/mTOR pathway. J Biol Chem (2005) 1.64
Multiple functions of Jab1 are required for early embryonic development and growth potential in mice. J Biol Chem (2004) 1.58
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Direct comparison of autologous and allogeneic transplantation of iPSC-derived neural cells in the brain of a non-human primate. Stem Cell Reports (2013) 1.48
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Magnesium supplementation prevents experimental chronic cyclosporine a nephrotoxicity via renin-angiotensin system independent mechanism. Transplantation (2002) 1.45
The effects of cardioactive drugs on cardiomyocytes derived from human induced pluripotent stem cells. Biochem Biophys Res Commun (2009) 1.45
In vitro pharmacologic testing using human induced pluripotent stem cell-derived cardiomyocytes. Biochem Biophys Res Commun (2009) 1.44
Adipogenic differentiation of human induced pluripotent stem cells: comparison with that of human embryonic stem cells. FEBS Lett (2009) 1.43
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Derivation conditions impact X-inactivation status in female human induced pluripotent stem cells. Cell Stem Cell (2012) 1.35
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Induction and enhancement of cardiac cell differentiation from mouse and human induced pluripotent stem cells with cyclosporin-A. PLoS One (2011) 1.33
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Bioengineered myocardium derived from induced pluripotent stem cells improves cardiac function and attenuates cardiac remodeling following chronic myocardial infarction in rats. Stem Cells Transl Med (2012) 1.30
Human induced pluripotent stem cells on autologous feeders. PLoS One (2009) 1.28
Generation of human melanocytes from induced pluripotent stem cells. PLoS One (2011) 1.27
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Anti-Aβ drug screening platform using human iPS cell-derived neurons for the treatment of Alzheimer's disease. PLoS One (2011) 1.23
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Cell line-dependent differentiation of induced pluripotent stem cells into cardiomyocytes in mice. Cardiovasc Res (2010) 1.21
Pre-evaluated safe human iPSC-derived neural stem cells promote functional recovery after spinal cord injury in common marmoset without tumorigenicity. PLoS One (2012) 1.20
Specific lectin biomarkers for isolation of human pluripotent stem cells identified through array-based glycomic analysis. Cell Res (2011) 1.17
iPS cell technologies: significance and applications to CNS regeneration and disease. Mol Brain (2014) 1.14
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Induced pluripotent stem cells from CINCA syndrome patients as a model for dissecting somatic mosaicism and drug discovery. Blood (2012) 1.01
To be immunogenic, or not to be: that's the iPSC question. Cell Stem Cell (2013) 0.98
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Transplantation of mouse induced pluripotent stem cells into the cochlea. Neuroreport (2009) 0.96
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G(i)-coupled GPCR signaling controls the formation and organization of human pluripotent colonies. PLoS One (2009) 0.95
Induced pluripotent stem cells from patients with human fibrodysplasia ossificans progressiva show increased mineralization and cartilage formation. Orphanet J Rare Dis (2013) 0.94