Published in Nature on August 20, 2006
Mast cell interleukin-10 drives localized tolerance in chronic bladder infection. Immunity (2013) 1.80
Lymphocytes, neuropeptides, and genes involved in alopecia areata. J Clin Invest (2007) 1.56
CD19 regulates skin and lung fibrosis via Toll-like receptor signaling in a model of bleomycin-induced scleroderma. Am J Pathol (2008) 1.23
The pathogenesis of primary cicatricial alopecias. Am J Pathol (2010) 1.09
Tolerance: an overview and perspectives. Nat Rev Nephrol (2010) 0.95
Abnormal interactions between perifollicular mast cells and CD8+ T-cells may contribute to the pathogenesis of alopecia areata. PLoS One (2014) 0.92
Leukocytes in glomerular injury. Semin Immunopathol (2007) 0.90
Mast cells are essential intermediaries in regulatory T-cell tolerance. Nature (2006) 5.49
Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes. N Engl J Med (2005) 10.16
Plasticity of Foxp3(+) T cells reflects promiscuous Foxp3 expression in conventional T cells but not reprogramming of regulatory T cells. Immunity (2012) 4.98
Heterogeneity of natural Foxp3+ T cells: a committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity. Proc Natl Acad Sci U S A (2009) 4.25
Clinical evidence of a graft-versus-Hodgkin's-lymphoma effect after reduced-intensity allogeneic transplantation. Lancet (2005) 4.09
Induction of foxP3+ regulatory T cells in the periphery of T cell receptor transgenic mice tolerized to transplants. J Immunol (2004) 3.62
Identification of regulatory T cells in tolerated allografts. J Exp Med (2002) 3.60
High incidence of cytomegalovirus infection after nonmyeloablative stem cell transplantation: potential role of Campath-1H in delaying immune reconstitution. Blood (2002) 2.96
Lymphocyte homeostasis following therapeutic lymphocyte depletion in multiple sclerosis. Eur J Immunol (2005) 2.74
Limiting transplantation-related mortality following unrelated donor stem cell transplantation by using a nonmyeloablative conditioning regimen. Blood (2002) 2.56
The window of therapeutic opportunity in multiple sclerosis: evidence from monoclonal antibody therapy. J Neurol (2005) 2.44
Infectious tolerance via the consumption of essential amino acids and mTOR signaling. Proc Natl Acad Sci U S A (2009) 2.22
The plasticity and stability of regulatory T cells. Nat Rev Immunol (2013) 2.15
Mouse glucocorticoid-induced tumor necrosis factor receptor ligand is costimulatory for T cells. Proc Natl Acad Sci U S A (2003) 2.14
Specific subsets of murine dendritic cells acquire potent T cell regulatory functions following CTLA4-mediated induction of indoleamine 2,3 dioxygenase. Int Immunol (2004) 2.13
Autoimmune diabetes onset results from qualitative rather than quantitative age-dependent changes in pathogenic T-cells. Diabetes (2005) 2.10
Both CD4(+)CD25(+) and CD4(+)CD25(-) regulatory cells mediate dominant transplantation tolerance. J Immunol (2002) 1.85
Activated regulatory T cells are the major T cell type emigrating from the skin during a cutaneous immune response in mice. J Clin Invest (2010) 1.83
Critical influence of natural regulatory CD25+ T cells on the fate of allografts in the absence of immunosuppression. Transplantation (2005) 1.66
Dominant transplantation tolerance impairs CD8+ T cell function but not expansion. Nat Immunol (2002) 1.55
Accelerated memory cell homeostasis during T cell depletion and approaches to overcome it. J Immunol (2006) 1.51
Sustained suppression by Foxp3+ regulatory T cells is vital for infectious transplantation tolerance. J Exp Med (2011) 1.43
Transient Epstein-Barr virus reactivation in CD3 monoclonal antibody-treated patients. Blood (2009) 1.37
Embryonic stem cell-derived tissues are immunogenic but their inherent immune privilege promotes the induction of tolerance. Proc Natl Acad Sci U S A (2007) 1.34
Immune privilege induced by regulatory T cells in transplantation tolerance. Immunol Rev (2006) 1.27
A key role for TGF-beta signaling to T cells in the long-term acceptance of allografts. J Immunol (2007) 1.27
Regulatory T cells and dendritic cells in transplantation tolerance: molecular markers and mechanisms. Immunol Rev (2003) 1.26
Regulatory T cells overexpress a subset of Th2 gene transcripts. J Immunol (2002) 1.25
The role of Sp1 and NF-kappa B in regulating CD40 gene expression. J Biol Chem (2001) 1.23
Alemtuzumab (CAMPATH 1H) induction therapy in cadaveric kidney transplantation--efficacy and safety at five years. Am J Transplant (2005) 1.22
mTOR signalling and metabolic regulation of T cell differentiation. Curr Opin Immunol (2010) 1.20
IL-10-conditioned dendritic cells, decommissioned for recruitment of adaptive immunity, elicit innate inflammatory gene products in response to danger signals. J Immunol (2004) 1.18
Connecting the mechanisms of T-cell regulation: dendritic cells as the missing link. Immunol Rev (2010) 1.17
Generation of anti-inflammatory adenosine by leukocytes is regulated by TGF-β. Eur J Immunol (2011) 1.16
The nuclear orphan receptor Nr4a2 induces Foxp3 and regulates differentiation of CD4+ T cells. Nat Commun (2011) 1.15
Induction of regulatory T cells and dominant tolerance by dendritic cells incapable of full activation. J Immunol (2007) 1.12
Donor-specific transplantation tolerance: the paradoxical behavior of CD4+CD25+ T cells. Proc Natl Acad Sci U S A (2004) 1.11
A novel strategy to reduce the immunogenicity of biological therapies. J Immunol (2010) 1.10
The vaccinia virus C12L protein inhibits mouse IL-18 and promotes virus virulence in the murine intranasal model. J Gen Virol (2002) 1.10
Enhanced production of IL-10 by dendritic cells deficient in CIITA. J Immunol (2005) 1.09
Dominant tolerance: activation thresholds for peripheral generation of regulatory T cells. Trends Immunol (2005) 1.07
Generation of anergic and regulatory T cells following prolonged exposure to a harmless antigen. J Immunol (2004) 1.06
In vivo kinetics of GITR and GITR ligand expression and their functional significance in regulating viral immunopathology. J Virol (2005) 1.06
CD8+ lymphocytes do not mediate protection against acute superinfection 20 days after vaccination with a live attenuated simian immunodeficiency virus. J Virol (2005) 1.05
Tmem176B and Tmem176A are associated with the immature state of dendritic cells. J Leukoc Biol (2010) 1.05
Embryonic stem cells: overcoming the immunological barriers to cell replacement therapy. Curr Stem Cell Res Ther (2009) 1.04
TGF-β-mediated Foxp3 gene expression is cooperatively regulated by Stat5, Creb, and AP-1 through CNS2. J Immunol (2013) 1.02
Morbidity and mortality in rheumatoid arthritis patients with prolonged therapy-induced lymphopenia: twelve-year outcomes. Arthritis Rheum (2008) 1.01
Expression of human GITRL on myeloid dendritic cells enhances their immunostimulatory function but does not abrogate the suppressive effect of CD4+CD25+ regulatory T cells. J Leukoc Biol (2007) 0.97
Pharmacokinetics and antibody responses to the CD3 antibody otelixizumab used in the treatment of type 1 diabetes. J Clin Pharmacol (2010) 0.96
Human CD3 transgenic mice: preclinical testing of antibodies promoting immune tolerance. Sci Transl Med (2011) 0.96
Harnessing FOXP3+ regulatory T cells for transplantation tolerance. J Clin Invest (2014) 0.95
Neutralizing tumor necrosis factor activity leads to remission in patients with refractory noninfectious posterior uveitis. Arch Ophthalmol (2004) 0.95
Biomarkers of transplantation tolerance: more hopeful than helpful? Front Immunol (2011) 0.94
TGF-β in transplantation tolerance. Curr Opin Immunol (2011) 0.93
Embryonic stem cells and the challenge of transplantation tolerance. Trends Immunol (2004) 0.93
Induction of immunological tolerance/hyporesponsiveness in baboons with a nondepleting CD4 antibody. J Immunol (2004) 0.92
Loss of the TGFβ-activating integrin αvβ8 on dendritic cells protects mice from chronic intestinal parasitic infection via control of type 2 immunity. PLoS Pathog (2013) 0.92
Anti-CD45 monoclonal antibody YAML568: A promising radioimmunoconjugate for targeted therapy of acute leukemia. J Nucl Med (2006) 0.92
Structural basis for ligand-mediated mouse GITR activation. Proc Natl Acad Sci U S A (2008) 0.92
Exacerbation of delayed-type hypersensitivity responses in EBV-induced gene-3 (EBI-3)-deficient mice. Immunol Lett (2010) 0.91
Generation of immunogenic dendritic cells from human embryonic stem cells without serum and feeder cells. Regen Med (2009) 0.91
Key role of the GITR/GITRLigand pathway in the development of murine autoimmune diabetes: a potential therapeutic target. PLoS One (2009) 0.90
Infectious tolerance: therapeutic potential. Curr Opin Immunol (2010) 0.90
Dominant transplantation tolerance. Opinion. Curr Opin Immunol (2003) 0.90
Enhanced efficacy from gene therapy in Pompe disease using coreceptor blockade. Hum Gene Ther (2015) 0.90
Induction of dominant transplantation tolerance by an altered peptide ligand of the male antigen Dby. J Clin Invest (2004) 0.89
Immune reconstitution at 6 months following T-cell depleted hematopoietic stem cell transplantation is predictive for treatment outcome. Transplantation (2002) 0.89
Partial and transient modulation of the CD3-T-cell receptor complex, elicited by low-dose regimens of monoclonal anti-CD3, is sufficient to induce disease remission in non-obese diabetic mice. Immunology (2010) 0.89
MS4A4B is a GITR-associated membrane adapter, expressed by regulatory T cells, which modulates T cell activation. J Immunol (2009) 0.89
Co-receptor and co-stimulation blockade for mixed chimerism and tolerance without myelosuppressive conditioning. BMC Immunol (2006) 0.88
Expansion of Foxp3(+) T-cell populations by Candida albicans enhances both Th17-cell responses and fungal dissemination after intravenous challenge. Eur J Immunol (2014) 0.87
A role for regulatory T cells in acceptance of ESC-derived tissues transplanted across an major histocompatibility complex barrier. Stem Cells (2010) 0.87
Resistance of regulatory T cells to glucocorticoid-induced [corrected] TNFR family-related protein (GITR) during Plasmodium yoelii infection. Eur J Immunol (2005) 0.87
T-cell depletion with Campath-1H "in the bag" for matched related allogeneic peripheral blood stem cell transplantation is associated with reduced graft-versus-host disease, rapid immune constitution and improved survival. Br J Haematol (2003) 0.86
Embryonic stem cells: protecting pluripotency from alloreactivity. Curr Opin Immunol (2007) 0.86
Reduced-intensity transplantation with in vivo T-cell depletion and adjuvant dose-escalating donor lymphocyte infusions for chemotherapy-sensitive myeloma: limited efficacy of graft-versus-tumor activity. Biol Blood Marrow Transplant (2003) 0.86
Regulatory cells and transplantation tolerance. Cold Spring Harb Perspect Med (2013) 0.86
Regulatory T cells in the induction and maintenance of peripheral transplantation tolerance. Transpl Int (2003) 0.86
Alemtuzumab (CAMPATH-1H) for the treatment of acute rejection in kidney transplant recipients: long-term follow-up. Transplantation (2009) 0.85
Induction of Immunological Tolerance as a Therapeutic Procedure. Microbiol Spectr (2016) 0.83
Tolerogenicity is not an absolute property of a dendritic cell. Eur J Immunol (2010) 0.82
Antibody-induced transplantation tolerance: the role of dominant regulation. Immunol Res (2003) 0.82
Enhancement of humoral and cellular immunity with an anti-glucocorticoid-induced tumour necrosis factor receptor monoclonal antibody. Immunology (2010) 0.82
Foxp3 expression is required for the induction of therapeutic tissue tolerance. J Immunol (2012) 0.81
Ectopic transplantation of tissues under the kidney capsule. Methods Mol Biol (2007) 0.80
CD3 monoclonal antibodies: a first step towards operational immune tolerance in the clinic. Rev Diabet Stud (2012) 0.80
Embryonic stem cells: a novel source of dendritic cells for clinical applications. Int Immunopharmacol (2005) 0.80
Secreted and transmembrane 1A is a novel co-stimulatory ligand. PLoS One (2013) 0.79
Enhanced murine contact hypersensitivity by depletion of endogenous regulatory T cells in the sensitization phase. J Dermatol Sci (2010) 0.79
Cell replacement therapy and the evasion of destructive immunity. Stem Cell Rev (2005) 0.78
Regulatory T cells and transplantation tolerance. Immunotherapy (2013) 0.78
Probing dendritic cell function by guiding the differentiation of embryonic stem cells. Methods Enzymol (2003) 0.78
Serial analysis of gene expression provides new insights into regulatory T cells. Semin Immunol (2003) 0.78
Gene expression in the Gitr locus is regulated by NF-κB and Foxp3 through an enhancer. J Immunol (2014) 0.78
Reprogramming the immune system using antibodies. Methods Mol Biol (2006) 0.77
The new immunosuppression: just kill the T cell. Nat Med (2003) 0.76