Published in Liver Int on October 01, 2006
Antagonism of the chemokine Ccl5 ameliorates experimental liver fibrosis in mice. J Clin Invest (2010) 2.87
Fast food diet mouse: novel small animal model of NASH with ballooning, progressive fibrosis, and high physiological fidelity to the human condition. Am J Physiol Gastrointest Liver Physiol (2011) 1.85
Hepatic stellate cell transdifferentiation involves genome-wide remodeling of the DNA methylation landscape. J Hepatol (2015) 1.49
Experimental liver fibrosis research: update on animal models, legal issues and translational aspects. Fibrogenesis Tissue Repair (2013) 1.27
The role of mouse strain differences in the susceptibility to fibrosis: a systematic review. Fibrogenesis Tissue Repair (2013) 1.13
Stress signaling in the methionine-choline-deficient model of murine fatty liver disease. Gastroenterology (2010) 1.13
New insights from rodent models of fatty liver disease. Antioxid Redox Signal (2011) 1.03
An experimental assessment of in silico haplotype association mapping in laboratory mice. BMC Genet (2009) 0.99
In vitro and in vivo models of non-alcoholic fatty liver disease (NAFLD). Int J Mol Sci (2013) 0.97
The genetic architecture of NAFLD among inbred strains of mice. Elife (2015) 0.92
Dissociation of hepatic insulin resistance from susceptibility of nonalcoholic fatty liver disease induced by a high-fat and high-carbohydrate diet in mice. Am J Physiol Gastrointest Liver Physiol (2014) 0.84
Haplotype Association Mapping Identifies a Candidate Gene Region in Mice Infected With Staphylococcus aureus. G3 (Bethesda) (2012) 0.83
Specific Macronutrients Exert Unique Influences on the Adipose-Liver Axis to Promote Hepatic Steatosis in Mice. Cell Mol Gastroenterol Hepatol (2017) 0.83
An improved mouse model that rapidly develops fibrosis in non-alcoholic steatohepatitis. Int J Exp Pathol (2013) 0.81
Quantitative trait loci affecting liver fat content in mice. G3 (Bethesda) (2012) 0.79
Identification of eQTLs for hepatic Xbp1s and Socs3 gene expression in mice fed a high-fat, high-caloric diet. G3 (Bethesda) (2015) 0.75
The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nat Genet (2004) 9.37
Association between sustained virological response and all-cause mortality among patients with chronic hepatitis C and advanced hepatic fibrosis. JAMA (2012) 7.62
Phase II study of bevacizumab plus temozolomide during and after radiation therapy for patients with newly diagnosed glioblastoma multiforme. J Clin Oncol (2010) 4.23
The nature and identification of quantitative trait loci: a community's view. Nat Rev Genet (2003) 3.96
The methionine-choline deficient dietary model of steatohepatitis does not exhibit insulin resistance. J Hepatol (2004) 2.96
Non-selective betablocker therapy decreases intestinal permeability and serum levels of LBP and IL-6 in patients with cirrhosis. J Hepatol (2012) 2.93
A genome-wide association scan identifies the hepatic cholesterol transporter ABCG8 as a susceptibility factor for human gallstone disease. Nat Genet (2007) 2.75
Patients with acute on chronic liver failure display "sepsis-like" immune paralysis. J Hepatol (2005) 2.66
Ursodeoxycholic acid aggravates bile infarcts in bile duct-ligated and Mdr2 knockout mice via disruption of cholangioles. Gastroenterology (2002) 2.64
Mechanisms of hepatic steatosis in mice fed a lipogenic methionine choline-deficient diet. J Lipid Res (2008) 2.21
Complement factor 5 is a quantitative trait gene that modifies liver fibrogenesis in mice and humans. Nat Genet (2005) 2.20
Obese and diabetic db/db mice develop marked liver fibrosis in a model of nonalcoholic steatohepatitis: role of short-form leptin receptors and osteopontin. Am J Physiol Gastrointest Liver Physiol (2004) 2.10
Regurgitation of bile acids from leaky bile ducts causes sclerosing cholangitis in Mdr2 (Abcb4) knockout mice. Gastroenterology (2004) 2.02
Massive and submassive pulmonary embolism: experience with an algorithm for catheter-directed mechanical thrombectomy. Ann Vasc Surg (2011) 1.98
Upregulation of osteopontin expression is involved in the development of nonalcoholic steatohepatitis in a dietary murine model. Am J Physiol Gastrointest Liver Physiol (2004) 1.86
Intrahepatic cholestasis of pregnancy: Amelioration of pruritus by UDCA is associated with decreased progesterone disulphates in urine. Hepatology (2008) 1.82
Percutaneous angioplasty and stenting of the superficial femoral artery. J Vasc Surg (2005) 1.77
Genetic variation in the PNPLA3 gene is associated with alcoholic liver injury in caucasians. Hepatology (2010) 1.65
Characteristics of oesophageal bolus transport in patients with mild oesophagitis. Eur J Gastroenterol Hepatol (2005) 1.64
Ezetimibe prevents cholesterol gallstone formation in mice. Liver Int (2008) 1.62
Carotid artery stenting in elderly patients: importance of case selection. Catheter Cardiovasc Interv (2008) 1.61
Hemodynamic benefits of regional anesthesia for carotid endarterectomy. J Vasc Surg (2002) 1.61
Biliary cast syndrome in sclerosing cholangitis. Dig Liver Dis (2010) 1.55
Hyperglycemia at admission to the intensive care unit is associated with elevated serum concentrations of interleukin-6 and reduced ex vivo secretion of tumor necrosis factor-alpha. Crit Care Med (2004) 1.55
Genetic and environmental influences on symptomatic gallstone disease: a Swedish study of 43,141 twin pairs. Hepatology (2005) 1.55
International retrospective study of over 1000 adults with anaplastic oligodendroglial tumors. Neuro Oncol (2011) 1.53
Genetic and functional identification of the likely causative variant for cholesterol gallstone disease at the ABCG5/8 lithogenic locus. Hepatology (2013) 1.53
One-year clinical outcomes, midterm survival, and predictors of mortality after carotid stenting in elderly patients. Circulation (2009) 1.50
Standards of practice: carotid angioplasty and stenting. J Vasc Surg (2004) 1.49
Antifibrotic effects of CXCL9 and its receptor CXCR3 in livers of mice and humans. Gastroenterology (2009) 1.47
Phytosterol and cholesterol precursor levels indicate increased cholesterol excretion and biosynthesis in gallstone disease. Hepatology (2012) 1.47
Functional variants of the central bile acid sensor FXR identified in intrahepatic cholestasis of pregnancy. Gastroenterology (2007) 1.46
Endoleak management following endovascular aneurysm repair. J Vasc Interv Radiol (2008) 1.36
Intrahepatic cholestasis of pregnancy: a randomized controlled trial comparing dexamethasone and ursodeoxycholic acid. Hepatology (2005) 1.35
Safety of anticoagulation use and bevacizumab in patients with glioma. Neuro Oncol (2008) 1.25
The genetics of complex cholestatic disorders. Gastroenterology (2013) 1.24
Genome-wide analysis of hepatic fibrosis in inbred mice identifies the susceptibility locus Hfib1 on chromosome 15. Gastroenterology (2002) 1.21
The etiology of liver damage imparts cytokines transforming growth factor beta1 or interleukin-13 as driving forces in fibrogenesis. Hepatology (2009) 1.21
Nucleotide-binding oligomerization domain containing 2 (NOD2) variants are genetic risk factors for death and spontaneous bacterial peritonitis in liver cirrhosis. Hepatology (2010) 1.20
Pentoxifylline attenuates steatohepatitis induced by the methionine choline deficient diet. J Hepatol (2004) 1.19
Atorvastatin attenuates hepatic fibrosis in rats after bile duct ligation via decreased turnover of hepatic stellate cells. J Hepatol (2010) 1.18
Structural and mechanistic studies of Escherichia coli nitroreductase with the antibiotic nitrofurazone. Reversed binding orientations in different redox states of the enzyme. J Biol Chem (2005) 1.16
Hepatic overexpression of murine Abcb11 increases hepatobiliary lipid secretion and reduces hepatic steatosis. J Biol Chem (2003) 1.15
Increased gallstone risk in humans conferred by common variant of hepatic ATP-binding cassette transporter for cholesterol. Hepatology (2007) 1.15
The PNPLA3 rs738409 148M/M genotype is a risk factor for liver cancer in alcoholic cirrhosis but shows no or weak association in hepatitis C cirrhosis. PLoS One (2011) 1.13
Gc-globulin: roles in response to injury. Clin Chem (2006) 1.12
Pentoxifylline for the treatment of non-alcoholic steatohepatitis: a randomized controlled trial. Ann Hepatol (2011) 1.11
Interacting QTLs for cholesterol gallstones and gallbladder mucin in AKR and SWR strains of mice. Physiol Genomics (2002) 1.11
Interleukin-6 regulates hepatic transporters during acute-phase response. Biochem Biophys Res Commun (2004) 1.11
Rosette-forming glioneuronal tumor: a pineal region case with IDH1 and IDH2 mutation analyses and literature review of 43 cases. J Neurooncol (2010) 1.11
Variant adiponutrin (PNPLA3) represents a common fibrosis risk gene: non-invasive elastography-based study in chronic liver disease. J Hepatol (2010) 1.10
Correlating carotid artery stenosis detected by panoramic radiography with clinically relevant carotid artery stenosis determined by duplex ultrasound. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2002) 1.09
Complement C5 mediates experimental tubulointerstitial fibrosis. J Am Soc Nephrol (2007) 1.08
Transforming growth factor-beta1 gene polymorphisms are associated with progression of liver fibrosis in Caucasians with chronic hepatitis C infection. World J Gastroenterol (2005) 1.07
The fractalkine receptor CX3CR1 is involved in liver fibrosis due to chronic hepatitis C infection. J Hepatol (2007) 1.06
Rotational muscle flap closure for acute groin wound infections following vascular surgery. Ann Vasc Surg (2004) 1.06
IGF2 mRNA binding protein p62/IMP2-2 in hepatocellular carcinoma: antiapoptotic action is independent of IGF2/PI3K signaling. Am J Physiol Gastrointest Liver Physiol (2012) 1.06
The aldo-keto reductase AKR1C3 contributes to 7,12-dimethylbenz(a)anthracene-3,4-dihydrodiol mediated oxidative DNA damage in myeloid cells: implications for leukemogenesis. Mutat Res (2008) 1.04
FOXO transcription factors regulate innate immune mechanisms in respiratory epithelial cells. J Immunol (2013) 1.03
Hemodynamic effects of urotensin II and its specific receptor antagonist palosuran in cirrhotic rats. Hepatology (2008) 1.03
Genetic determinants in hepatic fibrosis: from experimental models to fibrogenic gene signatures in humans. Clin Liver Dis (2008) 1.03
Combined bezafibrate and medroxyprogesterone acetate: potential novel therapy for acute myeloid leukaemia. PLoS One (2009) 1.03
Cytokine-dependent regulation of hepatic organic anion transporter gene transactivators in mouse liver. Am J Physiol Gastrointest Liver Physiol (2005) 1.03
Gallstones: environment, lifestyle and genes. Dig Dis (2011) 1.02
Internal carotid artery pseudoaneurysms: treatment with the Wallgraft endoprosthesis. J Endovasc Ther (2003) 1.01
NASH--hepatic metabolism and not simply the metabolic syndrome. Hepatology (2003) 1.01
Variation of the gene encoding the nuclear bile salt receptor FXR and gallstone susceptibility in mice and humans. J Hepatol (2007) 1.00
Dysregulation of the unfolded protein response in db/db mice with diet-induced steatohepatitis. Hepatology (2011) 1.00
Vitamin D in chronic liver disease. Liver Int (2013) 1.00
Atorvastatin inhibits proliferation and apoptosis, but induces senescence in hepatic myofibroblasts and thereby attenuates hepatic fibrosis in rats. Lab Invest (2012) 0.99
Parenchyma-preserving hepatic resection for colorectal liver metastases. Langenbecks Arch Surg (2011) 0.99
Genome-wide association studies and genetic risk assessment of liver diseases. Nat Rev Gastroenterol Hepatol (2010) 0.99
Common variants of ABCB4 and ABCB11 and plasma lipid levels: a study in sib pairs with gallstones, and controls. Lipids (2009) 0.98
Haplotype-tagging RANTES gene variants influence response to antiviral therapy in chronic hepatitis C. Hepatology (2004) 0.98
Dissecting the genetic heterogeneity of gallbladder stone formation. Semin Liver Dis (2011) 0.97
Common genetic variation in vitamin D metabolism is associated with liver stiffness. Hepatology (2012) 0.96
PNPLA3-associated steatohepatitis: toward a gene-based classification of fatty liver disease. Semin Liver Dis (2013) 0.96
Homocysteine supplementation attenuates the unfolded protein response in a murine nutritional model of steatohepatitis. J Biol Chem (2009) 0.96
Cystic fibrosis-associated liver disease. Best Pract Res Clin Gastroenterol (2010) 0.96
Magnetic resonance imaging and magnetic resonance cholangiopancreaticography for diagnosis and pre-interventional evaluation of a fluid thoracic mass. Eur J Gastroenterol Hepatol (2003) 0.95
Association of familial colorectal cancer with variants in the E-cadherin (CDH1) and cyclin D1 (CCND1) genes. Int J Colorectal Dis (2007) 0.95
Innovative immunohistochemistry identifies MMP-9 expressing macrophages at the invasive front of murine HCC. World J Hepatol (2010) 0.95
Interleukin-6 plays a crucial role in the hepatic expression of SOCS3 during acute inflammatory processes in vivo. J Hepatol (2005) 0.95
A chronic high-cholesterol diet paradoxically suppresses hepatic CYP7A1 expression in FVB/NJ mice. J Lipid Res (2010) 0.94
Hepatobiliary organic anion transporters are differentially regulated in acute toxic liver injury induced by carbon tetrachloride. J Hepatol (2002) 0.94
Impedance characteristics of normal oesophageal motor function. Eur J Gastroenterol Hepatol (2003) 0.93
Serum vitamin B12 not reflecting vitamin B12 status in patients with type 2 diabetes. Biochimie (2012) 0.93
Optimal operative strategies in repair of juxtarenal abdominal aortic aneurysms. Ann Vasc Surg (2003) 0.93
Are plasma lipid levels related to ABCG5/ABCG8 polymorphisms? A preliminary study in siblings with gallstones. Eur J Intern Med (2006) 0.93
Initial treatment patterns over time for anaplastic oligodendroglial tumors. Neuro Oncol (2012) 0.92
Characterization of fasted-state human intestinal fluids collected from duodenum and jejunum. J Pharm Pharmacol (2006) 0.92
Consequences of bile duct obstruction on intestinal expression and function of multidrug resistance-associated protein 2. Gastroenterology (2004) 0.92
TACE plus sorafenib for the treatment of hepatocellular carcinoma: results of the multicenter, phase II SOCRATES trial. Cancer Chemother Pharmacol (2014) 0.91
Common heterozygous hemochromatosis gene mutations are risk factors for inflammation and fibrosis in chronic hepatitis C. Liver Int (2004) 0.91
The unfolded protein response in fatty liver disease. Semin Liver Dis (2013) 0.91
A frequent variant in the human bile salt export pump gene ABCB11 is associated with hepatitis C virus infection, but not liver stiffness in a German population. BMC Gastroenterol (2012) 0.90
Changes of the hepatic proteome in murine models for toxically induced fibrogenesis and sclerosing cholangitis. Proteomics (2006) 0.90
Technical considerations for late removal of aortic endografts. J Vasc Surg (2002) 0.89
Hemodynamics of distal revascularization-interval ligation. Ann Vasc Surg (2005) 0.89